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The map label for this gene is yqhD [H]

Identifier: 59712285

GI number: 59712285

Start: 1888956

End: 1890104

Strand: Direct

Name: yqhD [H]

Synonym: VF_1678

Alternate gene names: 59712285

Gene position: 1888956-1890104 (Clockwise)

Preceding gene: 59712283

Following gene: 59712289

Centisome position: 65.19

GC content: 40.3

Gene sequence:

>1149_bases
ATGAAATTCTCTTACGTTAACCCTACTCTAATCCATTTTGGCCAAGGTCAAATCGAAGCTATCGCAACATCTATTCCACA
AGACCAAAAAGTGCTTGTCATTTATGGTGGCGGTTCTATTAAACACAATGGTGTTTACGATCAAGTTGTCGCTGCTTTAT
CCAATCATACATGGCTTGAATTTTCAGGCGTAGAACCAAATCCAACAGTAGAAACATTAGATAAAGCGGTCACTATCGCT
AAAGAAGAAAACGTAGATTACATTCTTGCTGTTGGTGGTGGCTCAGTTATTGATGGCTCAAAATATGTTGCAGCAGCAAC
CAAATATGACGGTAATGGTTGGGATATCTTAATTGGTAAACACACAGTGACCGAAGCCGTTCCACTTGGCGCTATTTTAA
CGCTACCTGCAACGGGTTCAGAATCTAACTCTGGTGCTGTAATTACTCAAAAATCAACACAAACCAAACTGCCTTTCATG
GCTTCAGCAGTACAACCAAAATTTGCGGTTCTTGATCCTGATTCAATGAAGACATTACCAGAACGCCAATTAATTAACGG
GATTGTTGATGCTTGGGTTCATACTTGTGAGCAATATTTAACTATGCCAACTGGTGCAATGATACAGGATGGCTATGCCG
AAACCCTACTACGCAACTTACTGACTCTCGGTGCTCAATACGATGACCGTGACAATAATGAGTGGCGCTCAAACCTAATG
TGGACAGCTAACCAAGCGCTAAATGGCTTGATTGGTACAGGTGTTCCTCACGATTGGGCAACACATATGATTGGTCATGA
GTTAACTGCGCTTTATAACGTAGATCACGCACGCTCTTTATCTATCGTTCAACCGTCTTTACTTCGTAATCAAATCGAAG
CAAAACGAGCTAAATTAGAACAAATGGGTAAGAATGTATTTGGGCTTGTTTATACCGATGATTTAGCAGAACGTACTATC
ATTGAAATTGAAAACTTCTACCACAGCTTAAACTCTCCAACTGAGTTAACGGAGCATGGTAATGATAAAGCATCTACTAT
TGATGCCATTATCAAACAGCTTGAAGCTCACGGAATGGTTGCTTTAGGTGAACATCAGGCAATTACACCTGATGTATCAC
GTAAAATTCTTGAAGACGCTGTAAAATAA

Upstream 100 bases:

>100_bases
TTCGCCTTTATAGATCGCATACTAGCTACTAATATGCACTTATTGAAATAATAAGCTCTAGAAAATAGAGCATCCTTTTT
GGAAGAAATGAGGTACAACA

Downstream 100 bases:

>100_bases
CCGTCTAAATACTGACTCAGAATAATGTGTTCTGAGTCAGTATGATTTTACAAACTAGCTTATTGTTGTTTAAAGAAATC
AAAGCCTGTTAAATGCTCAG

Product: alcohol dehydrogenase, NAD(P)-dependent

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKFSYVNPTLIHFGQGQIEAIATSIPQDQKVLVIYGGGSIKHNGVYDQVVAALSNHTWLEFSGVEPNPTVETLDKAVTIA
KEENVDYILAVGGGSVIDGSKYVAAATKYDGNGWDILIGKHTVTEAVPLGAILTLPATGSESNSGAVITQKSTQTKLPFM
ASAVQPKFAVLDPDSMKTLPERQLINGIVDAWVHTCEQYLTMPTGAMIQDGYAETLLRNLLTLGAQYDDRDNNEWRSNLM
WTANQALNGLIGTGVPHDWATHMIGHELTALYNVDHARSLSIVQPSLLRNQIEAKRAKLEQMGKNVFGLVYTDDLAERTI
IEIENFYHSLNSPTELTEHGNDKASTIDAIIKQLEAHGMVALGEHQAITPDVSRKILEDAVK

Sequences:

>Translated_382_residues
MKFSYVNPTLIHFGQGQIEAIATSIPQDQKVLVIYGGGSIKHNGVYDQVVAALSNHTWLEFSGVEPNPTVETLDKAVTIA
KEENVDYILAVGGGSVIDGSKYVAAATKYDGNGWDILIGKHTVTEAVPLGAILTLPATGSESNSGAVITQKSTQTKLPFM
ASAVQPKFAVLDPDSMKTLPERQLINGIVDAWVHTCEQYLTMPTGAMIQDGYAETLLRNLLTLGAQYDDRDNNEWRSNLM
WTANQALNGLIGTGVPHDWATHMIGHELTALYNVDHARSLSIVQPSLLRNQIEAKRAKLEQMGKNVFGLVYTDDLAERTI
IEIENFYHSLNSPTELTEHGNDKASTIDAIIKQLEAHGMVALGEHQAITPDVSRKILEDAVK
>Mature_382_residues
MKFSYVNPTLIHFGQGQIEAIATSIPQDQKVLVIYGGGSIKHNGVYDQVVAALSNHTWLEFSGVEPNPTVETLDKAVTIA
KEENVDYILAVGGGSVIDGSKYVAAATKYDGNGWDILIGKHTVTEAVPLGAILTLPATGSESNSGAVITQKSTQTKLPFM
ASAVQPKFAVLDPDSMKTLPERQLINGIVDAWVHTCEQYLTMPTGAMIQDGYAETLLRNLLTLGAQYDDRDNNEWRSNLM
WTANQALNGLIGTGVPHDWATHMIGHELTALYNVDHARSLSIVQPSLLRNQIEAKRAKLEQMGKNVFGLVYTDDLAERTI
IEIENFYHSLNSPTELTEHGNDKASTIDAIIKQLEAHGMVALGEHQAITPDVSRKILEDAVK

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789386, Length=384, Percent_Identity=50.5208333333333, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI48994951, Length=255, Percent_Identity=25.8823529411765, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789163, Length=315, Percent_Identity=25.3968253968254, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787493, Length=372, Percent_Identity=24.1935483870968, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17537053, Length=149, Percent_Identity=30.8724832214765, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321181, Length=340, Percent_Identity=24.1176470588235, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 41658; Mature: 41658

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSYVNPTLIHFGQGQIEAIATSIPQDQKVLVIYGGGSIKHNGVYDQVVAALSNHTWLE
CCCCCCCCEEEEECCCHHHHHHHCCCCCCEEEEEECCCCEECCCHHHHHHHHHCCCCEEE
FSGVEPNPTVETLDKAVTIAKEENVDYILAVGGGSVIDGSKYVAAATKYDGNGWDILIGK
EECCCCCCHHHHHHHHHEEEECCCCCEEEEECCCCEECCCCEEEEEEEECCCCEEEEEEC
HTVTEAVPLGAILTLPATGSESNSGAVITQKSTQTKLPFMASAVQPKFAVLDPDSMKTLP
CHHHHHCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHCCCCEEEECCHHHHHCC
ERQLINGIVDAWVHTCEQYLTMPTGAMIQDGYAETLLRNLLTLGAQYDDRDNNEWRSNLM
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHCEE
WTANQALNGLIGTGVPHDWATHMIGHELTALYNVDHARSLSIVQPSLLRNQIEAKRAKLE
EEHHHHHCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHH
QMGKNVFGLVYTDDLAERTIIEIENFYHSLNSPTELTEHGNDKASTIDAIIKQLEAHGMV
HHCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCE
ALGEHQAITPDVSRKILEDAVK
EECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKFSYVNPTLIHFGQGQIEAIATSIPQDQKVLVIYGGGSIKHNGVYDQVVAALSNHTWLE
CCCCCCCCEEEEECCCHHHHHHHCCCCCCEEEEEECCCCEECCCHHHHHHHHHCCCCEEE
FSGVEPNPTVETLDKAVTIAKEENVDYILAVGGGSVIDGSKYVAAATKYDGNGWDILIGK
EECCCCCCHHHHHHHHHEEEECCCCCEEEEECCCCEECCCCEEEEEEEECCCCEEEEEEC
HTVTEAVPLGAILTLPATGSESNSGAVITQKSTQTKLPFMASAVQPKFAVLDPDSMKTLP
CHHHHHCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHCCCCEEEECCHHHHHCC
ERQLINGIVDAWVHTCEQYLTMPTGAMIQDGYAETLLRNLLTLGAQYDDRDNNEWRSNLM
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHCEE
WTANQALNGLIGTGVPHDWATHMIGHELTALYNVDHARSLSIVQPSLLRNQIEAKRAKLE
EEHHHHHCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHH
QMGKNVFGLVYTDDLAERTIIEIENFYHSLNSPTELTEHGNDKASTIDAIIKQLEAHGMV
HHCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCE
ALGEHQAITPDVSRKILEDAVK
EECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]