Click here to switch to the map view.

The map label for this gene is csgA [H]

Identifier: 59712265

GI number: 59712265

Start: 1869968

End: 1870660

Strand: Direct

Name: csgA [H]

Synonym: VF_1658

Alternate gene names: 59712265

Gene position: 1869968-1870660 (Clockwise)

Preceding gene: 59712263

Following gene: 59712268

Centisome position: 64.54

GC content: 38.38

Gene sequence:

>693_bases
ATGAAACACATTTTCATTACAGGCGCTAACCGTGGTATTGGCTTATCTTTTGTAAAATACTATTTGCAGCAGGGCCATCA
AGTCAGTGCGACTTATCGTGATACCTCAACGGCTCAAGAGCTTCTTCAACTTGAAAATGACAATCCTGAACTTTCTTTGT
ATCAATTAGAACTGACTAATTACACTGCCATACAAGATGTAGCAAAAACGCTTTGCCATACTCCTATAGATATTCTAATT
AATAATGCCGGTTATTATGGCCCTAAAGGTTATGGTTTTGGGCACTGTGATGTTGAGGAATGGAAGAAAGTATTTGAAAT
CAATGCTATTGCACCACAAAAGCTCGTAGAAGCGCTCTACCCTAGCTTGCAATTAAGCCGTGATAAAACCATCGTATGTA
TTTCTTCTAAAGTCGGCAGCATGACAGAGAACACTTCAGGTGGAGGTTATATTTATCGTTCATCTAAGGCTGCATTAAAC
TCTGTAGTAAAAAGCTTAAGTAATGATTTAAAACCAGAAGGATTTACTGTTATTGCGATGCACCCAGGTTGGGTTCAAAC
AGAGATGGGCGGACCAAATGCTTTAATTTCAACAGAAGAGTCTGTGAAGGGATTAACGAAAGTCATTGCCCAACTATCCA
TTGAAAATAGTGGGCAATTTTTAAATTTTGATGGTACTGAATTACCTTGGTAG

Upstream 100 bases:

>100_bases
AGATGAGGCTATAGGCTCAAGGATTAACGTCTAAAATATAGAAACAATTTGTTTACATCTAAAAACACAACTTTTCCGTG
TAACAACATAAGGGATATTC

Downstream 100 bases:

>100_bases
TGGTTCTAAAATTCCGTTTCTTACCAAGCCACGTCGTACGTTTTTACACAGTTTAGCGAACTTATCAATCTCAGAGAAAT
TGGGCGTTTCACCACGCTCA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKHIFITGANRGIGLSFVKYYLQQGHQVSATYRDTSTAQELLQLENDNPELSLYQLELTNYTAIQDVAKTLCHTPIDILI
NNAGYYGPKGYGFGHCDVEEWKKVFEINAIAPQKLVEALYPSLQLSRDKTIVCISSKVGSMTENTSGGGYIYRSSKAALN
SVVKSLSNDLKPEGFTVIAMHPGWVQTEMGGPNALISTEESVKGLTKVIAQLSIENSGQFLNFDGTELPW

Sequences:

>Translated_230_residues
MKHIFITGANRGIGLSFVKYYLQQGHQVSATYRDTSTAQELLQLENDNPELSLYQLELTNYTAIQDVAKTLCHTPIDILI
NNAGYYGPKGYGFGHCDVEEWKKVFEINAIAPQKLVEALYPSLQLSRDKTIVCISSKVGSMTENTSGGGYIYRSSKAALN
SVVKSLSNDLKPEGFTVIAMHPGWVQTEMGGPNALISTEESVKGLTKVIAQLSIENSGQFLNFDGTELPW
>Mature_230_residues
MKHIFITGANRGIGLSFVKYYLQQGHQVSATYRDTSTAQELLQLENDNPELSLYQLELTNYTAIQDVAKTLCHTPIDILI
NNAGYYGPKGYGFGHCDVEEWKKVFEINAIAPQKLVEALYPSLQLSRDKTIVCISSKVGSMTENTSGGGYIYRSSKAALN
SVVKSLSNDLKPEGFTVIAMHPGWVQTEMGGPNALISTEESVKGLTKVIAQLSIENSGQFLNFDGTELPW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Escherichia coli, GI1787820, Length=187, Percent_Identity=31.5508021390374, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787335, Length=190, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17558990, Length=254, Percent_Identity=31.8897637795276, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17541382, Length=260, Percent_Identity=32.3076923076923, Blast_Score=103, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI193207563, Length=244, Percent_Identity=32.3770491803279, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17559964, Length=248, Percent_Identity=33.0645161290323, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17559962, Length=248, Percent_Identity=32.258064516129, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17558994, Length=244, Percent_Identity=30.7377049180328, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17558996, Length=251, Percent_Identity=29.8804780876494, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17532177, Length=241, Percent_Identity=31.1203319502075, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI72001658, Length=250, Percent_Identity=33.6, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17558992, Length=241, Percent_Identity=31.9502074688797, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17542178, Length=243, Percent_Identity=29.2181069958848, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=211, Percent_Identity=30.8056872037915, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322779, Length=246, Percent_Identity=33.739837398374, Blast_Score=112, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=30.1507537688442, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322226, Length=193, Percent_Identity=30.5699481865285, Blast_Score=62, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24640547, Length=248, Percent_Identity=33.4677419354839, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24643142, Length=193, Percent_Identity=32.1243523316062, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25303; Mature: 25303

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIFITGANRGIGLSFVKYYLQQGHQVSATYRDTSTAQELLQLENDNPELSLYQLELTN
CCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEEEEECC
YTAIQDVAKTLCHTPIDILINNAGYYGPKGYGFGHCDVEEWKKVFEINAIAPQKLVEALY
CHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHC
PSLQLSRDKTIVCISSKVGSMTENTSGGGYIYRSSKAALNSVVKSLSNDLKPEGFTVIAM
CCCEECCCCEEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEE
HPGWVQTEMGGPNALISTEESVKGLTKVIAQLSIENSGQFLNFDGTELPW
CCCEEEECCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCC
>Mature Secondary Structure
MKHIFITGANRGIGLSFVKYYLQQGHQVSATYRDTSTAQELLQLENDNPELSLYQLELTN
CCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEEEEECC
YTAIQDVAKTLCHTPIDILINNAGYYGPKGYGFGHCDVEEWKKVFEINAIAPQKLVEALY
CHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHC
PSLQLSRDKTIVCISSKVGSMTENTSGGGYIYRSSKAALNSVVKSLSNDLKPEGFTVIAM
CCCEECCCCEEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEE
HPGWVQTEMGGPNALISTEESVKGLTKVIAQLSIENSGQFLNFDGTELPW
CCCEEEECCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]