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The map label for this gene is tcpI [H]

Identifier: 59712259

GI number: 59712259

Start: 1861952

End: 1863838

Strand: Direct

Name: tcpI [H]

Synonym: VF_1652

Alternate gene names: 59712259

Gene position: 1861952-1863838 (Clockwise)

Preceding gene: 59712258

Following gene: 59712262

Centisome position: 64.26

GC content: 33.12

Gene sequence:

>1887_bases
ATGAATCTAACATTAAAAAATACAGTTTTTATATCCACATTTTCACTGTTATTTATAATATCAATAATTTTAACAGGAAC
AGGATATTTTACATTTAAAAATTACAACATTAACTCTACTGAAGAACATAAAAAAAATATTGGTGCTTTATTAGCTATCT
CATTAGAAGAGAACATAAACAGTTATTTTACTGCTATGGAAGCCTTATCTATCGATTTCGATAGCAATGGAAATATCAGT
GATATAAAACAAGCAACAACGAGTTTAGAATTATTACGTAAAAGTACGAATGTACCTTTAGTCTCTATTGGACTTAAGAA
TGGGTTAACGTTTGAAAATGGTGCTTTTATCCCTAATTTCAATGCAAAGGAAATGAAGAGAGAATGGTATCAGCGTACAT
TCAATGGTGAAACTAAAGTTATCACACAAGCTTATAACGATGCCGCAACTAACCGTACTGTTTTCGCCTTTTCAAGTCCC
CTTTATAAAAACAATGAAATTATTGCTGCAGTAGTTATTACAATTGAATTAGATACAATTAAAGAATTCATTAGTAAACT
TACACCTGAGAATCAGGTTTTTGTCTACGACAACAGTGGATATATTGTCTCTGCTCGTAGGGACCACTTAATCGGTAAAA
ATATATTTTCTGAACGTCCTGAATATAAAAGCTTTATTAATAATGAACTAAATTACAGCATTGATAATCGATATGTATCA
GCGTATAAAATAGAAGCACCATCAATAAATTGGAATGTTGTAAGTTATGAATGGGACGATGTTATTGCTCAACCAAGTAA
AGACATGTTAATTGATTCAATAATATTATTTGTTATCGTATTAAGTATCGCCCTGATTCTTGTTCACTTTTTATTAATAA
GATTAATTTATGCACCAATAGGTGGAGAGCCCGCTTATATTTCTTCTATTCTATCAAATATCGCAAATGGTAACCTATCT
GAAAAATTCACAATTACAGGCAAGGAAACAGGGATTTACGCATCCGCTATTGCCCTTAATCAAAAGTTATCATCAATAAT
CAAAAATAGCTTATTACTTTCTGATAGCGTGTCTTCGGCTTCCGAAGAACTAACACTAGTGATGAATGACACTTCAAACA
ACTCTCAACAAGAGTTAACCCAAGTTGAAGCTATCTCAACAGCGATAAACGAACTTTCGAGTACATCAAAAGAAGTGAGT
ATCAATGCGCTGCATGCGGAAAATGAAACACAAAACGCAATCAATAATGTGACGAAAGGATTAGAGGTTCTTAATTCTTC
GATTTCGCTAGCTAGCAATATCAATGATTCTGTTCAGCAAACAGCGGACATGATCTCAGAGCTTAAAATTAACTCTAACA
ATATTGGAGAAGTAACAACGGTTATCAGCTCTATTTCAGAACAAACTAACTTACTTGCACTAAACGCAGCAATCGAAGCT
GCTCGTGCTGGAGAGCAAGGACGAGGCTTTGCTGTTGTCGCTGATGAAGTCCGAAATTTAGCGGCAAAAACTCAAGAATC
GACAAAAAACATTCAAGAAATCATTCTTAAATTACAAGAGCAATCTGAAATTGCCAATACGAATATTGCTTCGAATGTTG
TTGCTATTCAAGAGTATATAAATCTGTCTGAAGATGTAAAAACTTCATTTGATAACATCGTTCTTTCTGTTCAATCTATC
TCTGATGTTAATACTCTTGTGGCAACAGCTTCACAAGAACAGTTAGCGGTAACAGAAAATATTGCTCAAAATACAACGGC
TACTTTTGATTTAGTACACCAAAACGTATCGGCAATAAACCAAACACAACAAGCTGCTGCTGAACTTTCGCAATTAGCTG
TATCACAAAAAAATGAGTTATCTTTCTTTTTAATAGATGATAAATAA

Upstream 100 bases:

>100_bases
AATTAACAACTCCCAAAGAAAGATAAATAAAGTCAAAAAGCCCCAGCTCAATTATAAATAAATTAAATATATTATTAATT
TTACCTAAGATGATCACATC

Downstream 100 bases:

>100_bases
TACAAAGAAGTGACAATAAGATATTTAAAGCCCTAACAGAGATGCTAGGGCTTTTTATATATGCGGGTAATTATTTTTGC
TTCGCAATCCACTGTTTAAC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MNLTLKNTVFISTFSLLFIISIILTGTGYFTFKNYNINSTEEHKKNIGALLAISLEENINSYFTAMEALSIDFDSNGNIS
DIKQATTSLELLRKSTNVPLVSIGLKNGLTFENGAFIPNFNAKEMKREWYQRTFNGETKVITQAYNDAATNRTVFAFSSP
LYKNNEIIAAVVITIELDTIKEFISKLTPENQVFVYDNSGYIVSARRDHLIGKNIFSERPEYKSFINNELNYSIDNRYVS
AYKIEAPSINWNVVSYEWDDVIAQPSKDMLIDSIILFVIVLSIALILVHFLLIRLIYAPIGGEPAYISSILSNIANGNLS
EKFTITGKETGIYASAIALNQKLSSIIKNSLLLSDSVSSASEELTLVMNDTSNNSQQELTQVEAISTAINELSSTSKEVS
INALHAENETQNAINNVTKGLEVLNSSISLASNINDSVQQTADMISELKINSNNIGEVTTVISSISEQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRNLAAKTQESTKNIQEIILKLQEQSEIANTNIASNVVAIQEYINLSEDVKTSFDNIVLSVQSI
SDVNTLVATASQEQLAVTENIAQNTTATFDLVHQNVSAINQTQQAAAELSQLAVSQKNELSFFLIDDK

Sequences:

>Translated_628_residues
MNLTLKNTVFISTFSLLFIISIILTGTGYFTFKNYNINSTEEHKKNIGALLAISLEENINSYFTAMEALSIDFDSNGNIS
DIKQATTSLELLRKSTNVPLVSIGLKNGLTFENGAFIPNFNAKEMKREWYQRTFNGETKVITQAYNDAATNRTVFAFSSP
LYKNNEIIAAVVITIELDTIKEFISKLTPENQVFVYDNSGYIVSARRDHLIGKNIFSERPEYKSFINNELNYSIDNRYVS
AYKIEAPSINWNVVSYEWDDVIAQPSKDMLIDSIILFVIVLSIALILVHFLLIRLIYAPIGGEPAYISSILSNIANGNLS
EKFTITGKETGIYASAIALNQKLSSIIKNSLLLSDSVSSASEELTLVMNDTSNNSQQELTQVEAISTAINELSSTSKEVS
INALHAENETQNAINNVTKGLEVLNSSISLASNINDSVQQTADMISELKINSNNIGEVTTVISSISEQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRNLAAKTQESTKNIQEIILKLQEQSEIANTNIASNVVAIQEYINLSEDVKTSFDNIVLSVQSI
SDVNTLVATASQEQLAVTENIAQNTTATFDLVHQNVSAINQTQQAAAELSQLAVSQKNELSFFLIDDK
>Mature_628_residues
MNLTLKNTVFISTFSLLFIISIILTGTGYFTFKNYNINSTEEHKKNIGALLAISLEENINSYFTAMEALSIDFDSNGNIS
DIKQATTSLELLRKSTNVPLVSIGLKNGLTFENGAFIPNFNAKEMKREWYQRTFNGETKVITQAYNDAATNRTVFAFSSP
LYKNNEIIAAVVITIELDTIKEFISKLTPENQVFVYDNSGYIVSARRDHLIGKNIFSERPEYKSFINNELNYSIDNRYVS
AYKIEAPSINWNVVSYEWDDVIAQPSKDMLIDSIILFVIVLSIALILVHFLLIRLIYAPIGGEPAYISSILSNIANGNLS
EKFTITGKETGIYASAIALNQKLSSIIKNSLLLSDSVSSASEELTLVMNDTSNNSQQELTQVEAISTAINELSSTSKEVS
INALHAENETQNAINNVTKGLEVLNSSISLASNINDSVQQTADMISELKINSNNIGEVTTVISSISEQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRNLAAKTQESTKNIQEIILKLQEQSEIANTNIASNVVAIQEYINLSEDVKTSFDNIVLSVQSI
SDVNTLVATASQEQLAVTENIAQNTTATFDLVHQNVSAINQTQQAAAELSQLAVSQKNELSFFLIDDK

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=312, Percent_Identity=30.4487179487179, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788194, Length=361, Percent_Identity=31.3019390581717, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI2367378, Length=304, Percent_Identity=29.6052631578947, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1787690, Length=344, Percent_Identity=27.0348837209302, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789453, Length=160, Percent_Identity=36.25, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 69002; Mature: 69002

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTLKNTVFISTFSLLFIISIILTGTGYFTFKNYNINSTEEHKKNIGALLAISLEENIN
CCEEECHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCEEEEEEEHHHHH
SYFTAMEALSIDFDSNGNISDIKQATTSLELLRKSTNVPLVSIGLKNGLTFENGAFIPNF
HHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCCC
NAKEMKREWYQRTFNGETKVITQAYNDAATNRTVFAFSSPLYKNNEIIAAVVITIELDTI
CHHHHHHHHHHHHCCCCCEEEEEHHCCCCCCCEEEEECCCCCCCCCEEEEEEEEEEHHHH
KEFISKLTPENQVFVYDNSGYIVSARRDHLIGKNIFSERPEYKSFINNELNYSIDNRYVS
HHHHHHCCCCCEEEEEECCCEEEEECCCHHHCCHHHHCCCHHHHHHCCCCCEEECCEEEE
AYKIEAPSINWNVVSYEWDDVIAQPSKDMLIDSIILFVIVLSIALILVHFLLIRLIYAPI
EEEEECCCCCEEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GGEPAYISSILSNIANGNLSEKFTITGKETGIYASAIALNQKLSSIIKNSLLLSDSVSSA
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHEECCCCCCC
SEELTLVMNDTSNNSQQELTQVEAISTAINELSSTSKEVSINALHAENETQNAINNVTKG
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHH
LEVLNSSISLASNINDSVQQTADMISELKINSNNIGEVTTVISSISEQTNLLALNAAIEA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHH
ARAGEQGRGFAVVADEVRNLAAKTQESTKNIQEIILKLQEQSEIANTNIASNVVAIQEYI
HHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NLSEDVKTSFDNIVLSVQSISDVNTLVATASQEQLAVTENIAQNTTATFDLVHQNVSAIN
CCCHHHHHHHHHHEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QTQQAAAELSQLAVSQKNELSFFLIDDK
HHHHHHHHHHHHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MNLTLKNTVFISTFSLLFIISIILTGTGYFTFKNYNINSTEEHKKNIGALLAISLEENIN
CCEEECHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCEEEEEEEHHHHH
SYFTAMEALSIDFDSNGNISDIKQATTSLELLRKSTNVPLVSIGLKNGLTFENGAFIPNF
HHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCCC
NAKEMKREWYQRTFNGETKVITQAYNDAATNRTVFAFSSPLYKNNEIIAAVVITIELDTI
CHHHHHHHHHHHHCCCCCEEEEEHHCCCCCCCEEEEECCCCCCCCCEEEEEEEEEEHHHH
KEFISKLTPENQVFVYDNSGYIVSARRDHLIGKNIFSERPEYKSFINNELNYSIDNRYVS
HHHHHHCCCCCEEEEEECCCEEEEECCCHHHCCHHHHCCCHHHHHHCCCCCEEECCEEEE
AYKIEAPSINWNVVSYEWDDVIAQPSKDMLIDSIILFVIVLSIALILVHFLLIRLIYAPI
EEEEECCCCCEEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GGEPAYISSILSNIANGNLSEKFTITGKETGIYASAIALNQKLSSIIKNSLLLSDSVSSA
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHEECCCCCCC
SEELTLVMNDTSNNSQQELTQVEAISTAINELSSTSKEVSINALHAENETQNAINNVTKG
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHH
LEVLNSSISLASNINDSVQQTADMISELKINSNNIGEVTTVISSISEQTNLLALNAAIEA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHH
ARAGEQGRGFAVVADEVRNLAAKTQESTKNIQEIILKLQEQSEIANTNIASNVVAIQEYI
HHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NLSEDVKTSFDNIVLSVQSISDVNTLVATASQEQLAVTENIAQNTTATFDLVHQNVSAIN
CCCHHHHHHHHHHEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QTQQAAAELSQLAVSQKNELSFFLIDDK
HHHHHHHHHHHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]