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The map label for this gene is dsbB

Identifier: 59712242

GI number: 59712242

Start: 1838855

End: 1839364

Strand: Direct

Name: dsbB

Synonym: VF_1635

Alternate gene names: 59712242

Gene position: 1838855-1839364 (Clockwise)

Preceding gene: 59712241

Following gene: 59712244

Centisome position: 63.46

GC content: 40.0

Gene sequence:

>510_bases
ATGCAAGCCCTTAATCACTTCTCACGCATTCGCCTATCTTGGTTTCTGCTACTACTTTGTATTATTTTTTTCGAAGCCTC
CGCACTGACCTTTCAACACATAATGAAACTTCCACCTTGTGTTATGTGTATTTATGAGCGTGTTGCAATGATGGGGATTG
GTGGCGCCGCTATTATTGGATTATTAAATCCAAATAACCTTATTATCCGCTGGTGTGGTTTCATTGCATGGGGGATCAGT
GCTGGGTGGGGGCTTAAGCTTGCACTTGAGCATGTTGATTTCCAATTAAATCCTTCACCATTTTCAACCTGCGATTTATT
TGTAACCTTCCCTTCATGGGCCCCATTAAATAAATGGGCACCGTGGATGTTTGAAGCTTATGGTGATTGCAGCAAAATCG
TATGGCAATTCTTAACGCTAACGATGCCTCAGTGGTTAGTTATTATTTTTGCGGGTAACTTAATTGCTTTGGCTATTTTT
GTTATCGCACAATTCTTCAATAAAAAATAA

Upstream 100 bases:

>100_bases
GTGCAACTTCTGCGATTTCTAGTGGTCATTAATAAGGTAAACTACTTTTGATAGCAAAGGCTCTGTAGATACGGGGCCTT
TATTTTTATAAGGAATAAAA

Downstream 100 bases:

>100_bases
TAGCAATATTGCTAATAGTAAAAAGCCACCACTAATTACGAATTAGTGATGGCTTTTTTATTTTTAGTGCTTTATTTACC
ACAACATTGTTTAAATTTCT

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MQALNHFSRIRLSWFLLLLCIIFFEASALTFQHIMKLPPCVMCIYERVAMMGIGGAAIIGLLNPNNLIIRWCGFIAWGIS
AGWGLKLALEHVDFQLNPSPFSTCDLFVTFPSWAPLNKWAPWMFEAYGDCSKIVWQFLTLTMPQWLVIIFAGNLIALAIF
VIAQFFNKK

Sequences:

>Translated_169_residues
MQALNHFSRIRLSWFLLLLCIIFFEASALTFQHIMKLPPCVMCIYERVAMMGIGGAAIIGLLNPNNLIIRWCGFIAWGIS
AGWGLKLALEHVDFQLNPSPFSTCDLFVTFPSWAPLNKWAPWMFEAYGDCSKIVWQFLTLTMPQWLVIIFAGNLIALAIF
VIAQFFNKK
>Mature_169_residues
MQALNHFSRIRLSWFLLLLCIIFFEASALTFQHIMKLPPCVMCIYERVAMMGIGGAAIIGLLNPNNLIIRWCGFIAWGIS
AGWGLKLALEHVDFQLNPSPFSTCDLFVTFPSWAPLNKWAPWMFEAYGDCSKIVWQFLTLTMPQWLVIIFAGNLIALAIF
VIAQFFNKK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family

Homologues:

Organism=Escherichia coli, GI1787433, Length=169, Percent_Identity=46.7455621301775, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBB_VIBF1 (Q5E4B6)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_205018.1
- ProteinModelPortal:   Q5E4B6
- SMR:   Q5E4B6
- STRING:   Q5E4B6
- GeneID:   3278902
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_1635
- NMPDR:   fig|312309.3.peg.1635
- eggNOG:   COG1495
- HOGENOM:   HBG637909
- OMA:   ALYFQHV
- PhylomeDB:   Q5E4B6
- ProtClustDB:   PRK01749
- BioCyc:   VFIS312309:VF1635-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00286
- InterPro:   IPR003752
- InterPro:   IPR022920

Pfam domain/function: PF02600 DsbB

EC number: NA

Molecular weight: Translated: 19265; Mature: 19265

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x117d104c)-; HASH(0x11b5bf68)-; HASH(0x11554998)-; HASH(0xb55b504)-;

Cys/Met content:

3.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALNHFSRIRLSWFLLLLCIIFFEASALTFQHIMKLPPCVMCIYERVAMMGIGGAAIIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHEEE
LLNPNNLIIRWCGFIAWGISAGWGLKLALEHVDFQLNPSPFSTCDLFVTFPSWAPLNKWA
EECCCHHHHHHHHHHHHHHCCCCCHHEEHHHCCEEECCCCCCEEEEEEECCCCCCCCCCC
PWMFEAYGDCSKIVWQFLTLTMPQWLVIIFAGNLIALAIFVIAQFFNKK
CHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MQALNHFSRIRLSWFLLLLCIIFFEASALTFQHIMKLPPCVMCIYERVAMMGIGGAAIIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHEEE
LLNPNNLIIRWCGFIAWGISAGWGLKLALEHVDFQLNPSPFSTCDLFVTFPSWAPLNKWA
EECCCHHHHHHHHHHHHHHCCCCCHHEEHHHCCEEECCCCCCEEEEEEECCCCCCCCCCC
PWMFEAYGDCSKIVWQFLTLTMPQWLVIIFAGNLIALAIFVIAQFFNKK
CHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA