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The map label for this gene is queC [H]

Identifier: 59712187

GI number: 59712187

Start: 1767795

End: 1768478

Strand: Direct

Name: queC [H]

Synonym: VF_1580

Alternate gene names: 59712187

Gene position: 1767795-1768478 (Clockwise)

Preceding gene: 59712186

Following gene: 59712190

Centisome position: 61.01

GC content: 39.33

Gene sequence:

>684_bases
ATGTCGACTGCAATCGTTGTATTTAGTGGCGGACAAGATTCCACCACTTGTTTAATTCAAGCATTAACTCAATATGATCA
TGTTCATTGTATTACTTTTGATTATGGCCAACGTCATAATCAAGAAATTGAAGTAGCGAAAAAAGTCTCGATTGAACTTG
GTGCAGCTTCTCATAAAGTCATGGATGTCGGCTTATTAAATGAATTAGCCGTGAGTTCACTTACTCGTGACAACATTCCT
GTTTCTCATGAGCTTCAAGAAAATGGCCTGCCAAACTCTTTCGTCCCAGGTCGTAATATTCTCTTCTTAACGCTTGCTGG
CATCTATGCGTATCAATTAGGCGCTGAAGCTGTCATTACAGGTGTCTGTGAGACAGATTTCTCAGGTTACCCAGATTGTC
GCGATGAGTTCGTAAAATCCATTAACCAATCTCTTGTTCTTGGTATGGATCGCCAACTTGAAATTAAAACACCACTAATG
TGGTTAAATAAAGCCGAAACATGGGCTCTTGCTGATAAGTATGGCAAATTAGATTATGTTCGTAATCATACTCTAACCTG
TTATAACGGTGTGATTGGTGACGGTTGTGGCGATTGCCCATCGTGTGATTTGCGCAAAAATGGCTTAGATGCTTACCTAG
AAAATAAAGAACCTGTAATGGCTGATTTAGAATCTAAACTCTAA

Upstream 100 bases:

>100_bases
GCTTAACACCATTTATTGGTATTAACCGCAAAGCCATCGATTATCGATGGCTTTTTTATTACAATATCAATAAATAACTC
TACTGAGATTTCCTATTATT

Downstream 100 bases:

>100_bases
AAAGCGTTATCTCTTTTAAAAATAAAAAGGCCACCACGATTAAGTGATGGCCTTTTTATTTACTTAAAAACCAATATTAA
TGGGAAATTCGCCCTTTAAT

Product: queuosine biosynthesis protein QueC

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSTAIVVFSGGQDSTTCLIQALTQYDHVHCITFDYGQRHNQEIEVAKKVSIELGAASHKVMDVGLLNELAVSSLTRDNIP
VSHELQENGLPNSFVPGRNILFLTLAGIYAYQLGAEAVITGVCETDFSGYPDCRDEFVKSINQSLVLGMDRQLEIKTPLM
WLNKAETWALADKYGKLDYVRNHTLTCYNGVIGDGCGDCPSCDLRKNGLDAYLENKEPVMADLESKL

Sequences:

>Translated_227_residues
MSTAIVVFSGGQDSTTCLIQALTQYDHVHCITFDYGQRHNQEIEVAKKVSIELGAASHKVMDVGLLNELAVSSLTRDNIP
VSHELQENGLPNSFVPGRNILFLTLAGIYAYQLGAEAVITGVCETDFSGYPDCRDEFVKSINQSLVLGMDRQLEIKTPLM
WLNKAETWALADKYGKLDYVRNHTLTCYNGVIGDGCGDCPSCDLRKNGLDAYLENKEPVMADLESKL
>Mature_226_residues
STAIVVFSGGQDSTTCLIQALTQYDHVHCITFDYGQRHNQEIEVAKKVSIELGAASHKVMDVGLLNELAVSSLTRDNIPV
SHELQENGLPNSFVPGRNILFLTLAGIYAYQLGAEAVITGVCETDFSGYPDCRDEFVKSINQSLVLGMDRQLEIKTPLMW
LNKAETWALADKYGKLDYVRNHTLTCYNGVIGDGCGDCPSCDLRKNGLDAYLENKEPVMADLESKL

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=227, Percent_Identity=70.0440528634361, Blast_Score=346, Evalue=6e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 25013; Mature: 24881

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAIVVFSGGQDSTTCLIQALTQYDHVHCITFDYGQRHNQEIEVAKKVSIELGAASHKV
CCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHEEEEECCCCCCE
MDVGLLNELAVSSLTRDNIPVSHELQENGLPNSFVPGRNILFLTLAGIYAYQLGAEAVIT
EEHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHCCHHEEE
GVCETDFSGYPDCRDEFVKSINQSLVLGMDRQLEIKTPLMWLNKAETWALADKYGKLDYV
EECCCCCCCCCCHHHHHHHHHHHHEEECCCCEEEECCCEEEECCCCCEEHHHHCCCCHHH
RNHTLTCYNGVIGDGCGDCPSCDLRKNGLDAYLENKEPVMADLESKL
HCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHCC
>Mature Secondary Structure 
STAIVVFSGGQDSTTCLIQALTQYDHVHCITFDYGQRHNQEIEVAKKVSIELGAASHKV
CEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHEEEEECCCCCCE
MDVGLLNELAVSSLTRDNIPVSHELQENGLPNSFVPGRNILFLTLAGIYAYQLGAEAVIT
EEHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHCCHHEEE
GVCETDFSGYPDCRDEFVKSINQSLVLGMDRQLEIKTPLMWLNKAETWALADKYGKLDYV
EECCCCCCCCCCHHHHHHHHHHHHEEECCCCEEEECCCEEEECCCCCEEHHHHCCCCHHH
RNHTLTCYNGVIGDGCGDCPSCDLRKNGLDAYLENKEPVMADLESKL
HCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA