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The map label for this gene is cdd

Identifier: 59712092

GI number: 59712092

Start: 1643290

End: 1644183

Strand: Direct

Name: cdd

Synonym: VF_1485

Alternate gene names: 59712092

Gene position: 1643290-1644183 (Clockwise)

Preceding gene: 59712091

Following gene: 59712094

Centisome position: 56.71

GC content: 41.95

Gene sequence:

>894_bases
ATGACAAGACTACAACAACGCTTAGAAGAAGCCCTAGCGAACTTACCTGACGCCCTGCGTACTTCATTAACACCAATTAT
TAATACTGAATTTAAAGGGGTAATTAGCAAGGAACAATTTCAATCACTGCAAGCTGACAGCCAGTTAAGCGATAAAGAAT
TACGTTTAGCTTTATTACCTCTTGCTGCTGCTTTCTCTGTTGCTCCTATTTCCAATTTTTATGTCGGTGCGATTGCTCGT
GGTTTGACTGGTAACCTTTATTTTGGCGCAAACATGGAATACAACGATGTTCAACTTGGCCAAACTATTCACGCTGAACA
GTCGGCAATTAGCCATGCATGGATCCAAGGTGAAACGGGTATTTCTAACATTACGATCAACTTCAGCCCTTGTGGTCACT
GTCGTCAATTTATGAATGAGCTAACAACCGCTGATTCTTTAATGGTTCAACTTCCTGAGCGTAATGAAAAATCACTGCAA
GAATACTTACCTGAGTCTTTTGGTCCTAAAGATTTAGGCATTGAAGGCGGATTACTTGCTCCTCTTTCGCACAACTTAGC
GTTAGAAACTGAGTCTCCACTGCTACGTAAAGCATTAGAAGCGGCAAACCGCAGTCACGCGCCTTACTCACATAATTTAA
GTGGTATTGCGCTTGAGATGGAAAGTGGTGAAGTGTATTACGGTATGTATGCTGAAAATGCGGCGTTTAACCCAAGCTTA
CCACCACTGCAAGTGGCGCTGGTTCATGCAAATATGTCTCGTGAAGACATCTTAACGGTTAAATCAGCTGCGCTAGTTGA
AGATCACAAAGGCGCTATTAGCCACCTTGCGATTACACAAAGCACATTAGAAGCACTAAATCCGGATGTAACATTAGAAT
ACGCTTCTTTATAA

Upstream 100 bases:

>100_bases
TTTATGTAACTTTACATCAATGAGTGTGATTTTGATCTATGTTTCCAGCTCAATTGTCACTAAAATGATCCTATAAGAAC
TTAAAAGGATCACCCTACTC

Downstream 100 bases:

>100_bases
GAATCAGGGTTTACTCTTTAAATAGATGACTTAAAAGGAGGCTTTATTGGCCTCCTTTTTATTTGATTAACATTTTTAAT
GTCTATTGATTGCCTTTCCA

Product: cytidine deaminase

Products: NA

Alternate protein names: Cytidine aminohydrolase; CDA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTRLQQRLEEALANLPDALRTSLTPIINTEFKGVISKEQFQSLQADSQLSDKELRLALLPLAAAFSVAPISNFYVGAIAR
GLTGNLYFGANMEYNDVQLGQTIHAEQSAISHAWIQGETGISNITINFSPCGHCRQFMNELTTADSLMVQLPERNEKSLQ
EYLPESFGPKDLGIEGGLLAPLSHNLALETESPLLRKALEAANRSHAPYSHNLSGIALEMESGEVYYGMYAENAAFNPSL
PPLQVALVHANMSREDILTVKSAALVEDHKGAISHLAITQSTLEALNPDVTLEYASL

Sequences:

>Translated_297_residues
MTRLQQRLEEALANLPDALRTSLTPIINTEFKGVISKEQFQSLQADSQLSDKELRLALLPLAAAFSVAPISNFYVGAIAR
GLTGNLYFGANMEYNDVQLGQTIHAEQSAISHAWIQGETGISNITINFSPCGHCRQFMNELTTADSLMVQLPERNEKSLQ
EYLPESFGPKDLGIEGGLLAPLSHNLALETESPLLRKALEAANRSHAPYSHNLSGIALEMESGEVYYGMYAENAAFNPSL
PPLQVALVHANMSREDILTVKSAALVEDHKGAISHLAITQSTLEALNPDVTLEYASL
>Mature_296_residues
TRLQQRLEEALANLPDALRTSLTPIINTEFKGVISKEQFQSLQADSQLSDKELRLALLPLAAAFSVAPISNFYVGAIARG
LTGNLYFGANMEYNDVQLGQTIHAEQSAISHAWIQGETGISNITINFSPCGHCRQFMNELTTADSLMVQLPERNEKSLQE
YLPESFGPKDLGIEGGLLAPLSHNLALETESPLLRKALEAANRSHAPYSHNLSGIALEMESGEVYYGMYAENAAFNPSLP
PLQVALVHANMSREDILTVKSAALVEDHKGAISHLAITQSTLEALNPDVTLEYASL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family

Homologues:

Organism=Escherichia coli, GI1788465, Length=284, Percent_Identity=48.2394366197183, Blast_Score=244, Evalue=4e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDD_VIBF1 (Q5E4R6)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_204868.1
- ProteinModelPortal:   Q5E4R6
- SMR:   Q5E4R6
- STRING:   Q5E4R6
- GeneID:   3277632
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_1485
- NMPDR:   fig|312309.3.peg.1485
- eggNOG:   COG0295
- HOGENOM:   HBG591160
- OMA:   NRSHAPY
- PhylomeDB:   Q5E4R6
- ProtClustDB:   PRK09027
- BioCyc:   VFIS312309:VF1485-MONOMER
- HAMAP:   MF_01558
- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013171
- InterPro:   IPR006263
- InterPro:   IPR016193
- InterPro:   IPR020797
- PIRSF:   PIRSF006334
- TIGRFAMs:   TIGR01355

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF08211 dCMP_cyt_deam_2; SSF53927 Cytidine_deaminase-like

EC number: =3.5.4.5

Molecular weight: Translated: 32347; Mature: 32216

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: ACT_SITE 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLQQRLEEALANLPDALRTSLTPIINTEFKGVISKEQFQSLQADSQLSDKELRLALLP
CCHHHHHHHHHHHCCCHHHHHHCCHHHCCHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHH
LAAAFSVAPISNFYVGAIARGLTGNLYFGANMEYNDVQLGQTIHAEQSAISHAWIQGETG
HHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCCCCEECCCHHHHHHHHHHHHEEECCCC
ISNITINFSPCGHCRQFMNELTTADSLMVQLPERNEKSLQEYLPESFGPKDLGIEGGLLA
CEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHCHHCCCCCCCCCCCCEEC
PLSHNLALETESPLLRKALEAANRSHAPYSHNLSGIALEMESGEVYYGMYAENAAFNPSL
CCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCCC
PPLQVALVHANMSREDILTVKSAALVEDHKGAISHLAITQSTLEALNPDVTLEYASL
CCEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECC
>Mature Secondary Structure 
TRLQQRLEEALANLPDALRTSLTPIINTEFKGVISKEQFQSLQADSQLSDKELRLALLP
CHHHHHHHHHHHCCCHHHHHHCCHHHCCHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHH
LAAAFSVAPISNFYVGAIARGLTGNLYFGANMEYNDVQLGQTIHAEQSAISHAWIQGETG
HHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCCCCEECCCHHHHHHHHHHHHEEECCCC
ISNITINFSPCGHCRQFMNELTTADSLMVQLPERNEKSLQEYLPESFGPKDLGIEGGLLA
CEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHCHHCCCCCCCCCCCCEEC
PLSHNLALETESPLLRKALEAANRSHAPYSHNLSGIALEMESGEVYYGMYAENAAFNPSL
CCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCCC
PPLQVALVHANMSREDILTVKSAALVEDHKGAISHLAITQSTLEALNPDVTLEYASL
CCEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA