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The map label for this gene is rbsC [H]

Identifier: 59712053

GI number: 59712053

Start: 1596784

End: 1597770

Strand: Direct

Name: rbsC [H]

Synonym: VF_1446

Alternate gene names: 59712053

Gene position: 1596784-1597770 (Clockwise)

Preceding gene: 59712052

Following gene: 59712054

Centisome position: 55.11

GC content: 43.87

Gene sequence:

>987_bases
ATGAGCACCAAATCAATGACTTCAACTGAAACACAACAAAAGAAAGGCGGCATTTTTTCTAAAGAGTGGCTGATTGAACA
AAAATCATTAATCGCGCTATTGCTTTTGATTGTCGTGGTATCCTTTTTGAACGACAACTTTTTTACTGTCGACAACATCC
TAAACATCCTACGTCAAACCTCAGTTAACGCGATTATTGCGGTAGGTATGACGTTAGTTATCTTAACGGCAGGTATCGAC
TTAAGCGTTGGCTCTGTATTAGCCCTTTGTGGTGCTTTTGCGGCAACCATGATTGGCCTTGAAATTCCGGTGATGATTGC
GGTTCCAACAGCACTACTTGCTGGTGCAGCTCTAGGTGCAATCAGCGGTATTATTATCGCAAAAGGTAAAGTTCAAGCAT
TCATTGCGACGCTAGTAACCATGACGTTATTACGTGGTGTGACAATGGTTTACACAGAAGGTCGCCCTATCTCTACTGGT
TTTACTGATGTTGCTGACAGCTTTGCATGGTTCGGTACAGGTTACGCGCTTGGTATCCCAGTTCCTATCTGGCTAATGGT
TATCGTGTTTGCATCTGTATGGTACTTACTAAACCACACACGTTTTGGTCGCTACGTTTATGCTCTAGGTGGCAATGAAT
CAGCAACTCGCCTATCTGGTATCAATGTGGATCGCGTTAAGATCGGTGTTTACGCTATCTGTGGTCTACTTGCTGCACTG
GCTGGTTTAATCGTAACGTCTCGTCTTTCTTCAGCTCAACCAACAGCAGGTATGGGCTACGAGCTAGACGCTATCGCAGC
GGTTGTACTTGGTGGTACAAGCCTTGCGGGTGGTAAAGGTCGCATCATGGGTACATTAATTGGTGCGCTTATCATCGGCT
TCTTAAACAACGCTCTGAACTTATTAGATGTTTCTTCTTACTACCAAATGATTGCCAAAGCAGTGGTTATCCTACTGGCA
GTATTAGTGGACAACAAAAACAAGTAA

Upstream 100 bases:

>100_bases
GCCGTATTAGTGGCGAATTCATGGCAAAAGATGCCGACCAAGAAAAATTATTGGCTTGTGCAGTAGGTAAAACTGTTGAG
CAAAATGTAGAGGTAACAGC

Downstream 100 bases:

>100_bases
CACCTTATTATTTATACAATAACTTATTACGAATACCCCTATAAATTCGTTTGCTGTTAACACAAAAATAGGCACAACCA
GACGTACCATGTTTGACTTG

Product: ribose ABC transporter permease protein

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSTKSMTSTETQQKKGGIFSKEWLIEQKSLIALLLLIVVVSFLNDNFFTVDNILNILRQTSVNAIIAVGMTLVILTAGID
LSVGSVLALCGAFAATMIGLEIPVMIAVPTALLAGAALGAISGIIIAKGKVQAFIATLVTMTLLRGVTMVYTEGRPISTG
FTDVADSFAWFGTGYALGIPVPIWLMVIVFASVWYLLNHTRFGRYVYALGGNESATRLSGINVDRVKIGVYAICGLLAAL
AGLIVTSRLSSAQPTAGMGYELDAIAAVVLGGTSLAGGKGRIMGTLIGALIIGFLNNALNLLDVSSYYQMIAKAVVILLA
VLVDNKNK

Sequences:

>Translated_328_residues
MSTKSMTSTETQQKKGGIFSKEWLIEQKSLIALLLLIVVVSFLNDNFFTVDNILNILRQTSVNAIIAVGMTLVILTAGID
LSVGSVLALCGAFAATMIGLEIPVMIAVPTALLAGAALGAISGIIIAKGKVQAFIATLVTMTLLRGVTMVYTEGRPISTG
FTDVADSFAWFGTGYALGIPVPIWLMVIVFASVWYLLNHTRFGRYVYALGGNESATRLSGINVDRVKIGVYAICGLLAAL
AGLIVTSRLSSAQPTAGMGYELDAIAAVVLGGTSLAGGKGRIMGTLIGALIIGFLNNALNLLDVSSYYQMIAKAVVILLA
VLVDNKNK
>Mature_327_residues
STKSMTSTETQQKKGGIFSKEWLIEQKSLIALLLLIVVVSFLNDNFFTVDNILNILRQTSVNAIIAVGMTLVILTAGIDL
SVGSVLALCGAFAATMIGLEIPVMIAVPTALLAGAALGAISGIIIAKGKVQAFIATLVTMTLLRGVTMVYTEGRPISTGF
TDVADSFAWFGTGYALGIPVPIWLMVIVFASVWYLLNHTRFGRYVYALGGNESATRLSGINVDRVKIGVYAICGLLAALA
GLIVTSRLSSAQPTAGMGYELDAIAAVVLGGTSLAGGKGRIMGTLIGALIIGFLNNALNLLDVSSYYQMIAKAVVILLAV
LVDNKNK

Specific function: Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790191, Length=323, Percent_Identity=70.8978328173375, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1790524, Length=330, Percent_Identity=39.6969696969697, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1788896, Length=324, Percent_Identity=36.4197530864198, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI145693152, Length=330, Percent_Identity=38.1818181818182, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1789992, Length=356, Percent_Identity=36.2359550561798, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI87082395, Length=297, Percent_Identity=39.7306397306397, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788471, Length=343, Percent_Identity=35.5685131195335, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI145693214, Length=249, Percent_Identity=38.5542168674699, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1787793, Length=289, Percent_Identity=31.1418685121107, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787794, Length=281, Percent_Identity=31.6725978647687, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 34412; Mature: 34281

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKSMTSTETQQKKGGIFSKEWLIEQKSLIALLLLIVVVSFLNDNFFTVDNILNILRQT
CCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHH
SVNAIIAVGMTLVILTAGIDLSVGSVLALCGAFAATMIGLEIPVMIAVPTALLAGAALGA
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ISGIIIAKGKVQAFIATLVTMTLLRGVTMVYTEGRPISTGFTDVADSFAWFGTGYALGIP
HHHHEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEECCC
VPIWLMVIVFASVWYLLNHTRFGRYVYALGGNESATRLSGINVDRVKIGVYAICGLLAAL
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHHH
AGLIVTSRLSSAQPTAGMGYELDAIAAVVLGGTSLAGGKGRIMGTLIGALIIGFLNNALN
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLDVSSYYQMIAKAVVILLAVLVDNKNK
HHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
STKSMTSTETQQKKGGIFSKEWLIEQKSLIALLLLIVVVSFLNDNFFTVDNILNILRQT
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHH
SVNAIIAVGMTLVILTAGIDLSVGSVLALCGAFAATMIGLEIPVMIAVPTALLAGAALGA
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ISGIIIAKGKVQAFIATLVTMTLLRGVTMVYTEGRPISTGFTDVADSFAWFGTGYALGIP
HHHHEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEECCC
VPIWLMVIVFASVWYLLNHTRFGRYVYALGGNESATRLSGINVDRVKIGVYAICGLLAAL
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHHH
AGLIVTSRLSSAQPTAGMGYELDAIAAVVLGGTSLAGGKGRIMGTLIGALIIGFLNNALN
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLDVSSYYQMIAKAVVILLAVLVDNKNK
HHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]