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The map label for this gene is czcR [H]

Identifier: 59711985

GI number: 59711985

Start: 1524221

End: 1525114

Strand: Direct

Name: czcR [H]

Synonym: VF_1378

Alternate gene names: 59711985

Gene position: 1524221-1525114 (Clockwise)

Preceding gene: 59711973

Following gene: 59711991

Centisome position: 52.6

GC content: 38.81

Gene sequence:

>894_bases
ATGCTCAATTTAAAACAGCTGGAAACGTTTGTCTGGATAGCGCATTTGGGGAGTTTTCGCCAAGCAGCAAAGCATTTATG
TACAACACAGCCTGCCATCTCTACGCGTATTGCAAATCTCGAAGAAACACTTAATACGGCATTGTTTTATCGTGATACTG
GTTCAATTTCATTAACAGCCAAAGGACGTGAATTATTACCTTTAGCCGAAAAGTTATTGAGCAACGCCGATCAATTACAA
GTTTTAGCAAACAGTGCTGAAGCAATATCTGGGATTTTACGGATTGGAGTTTCTGAAACGGTTGTACATACATGGTTACC
GCACTACTTAGCGCTTATTCATCAGAATTTACCTCACTTAGAGGTAGAGCTTATCGTTGATGCCACCATAAATTTACGAA
AAGAATTGCTAGCACGAAATATTGATATCGCGATTTTATTAGGAGTAGTTGATGAACCGAATGTGGTTAGTCAAGCCATC
TGTAATTACGATTTACACTGGGTGGCAAGCCCTGCATTACAACAAACACAAAAGAATAAAGTACTTAACTTTGCTCAGTG
GCCATTGATTACCTACGCCCGAAACACGTCACCATACTATGAAATAGAACGTTATTTTAATACGCACAATAATCAAGCAA
CACGCTTCTACTCTGCAAGTTCTCTATCCGCTAGTATTAGACTCGCTGAGAGTGGCATTGGTATCGCTATCCTACCTAAA
GAAGTCATACATACTTCTCTACAAAACAATACGCTAGAAATAATTGAAGCAGACTGGTCACCAAGTCCGCTTCAATTTTC
TGTTGCTTATATTGATACGCCAGTAAATCTGATGACAATGGAGTCAGTTAAACTTACTTTTGAGGCCGTGAAACAATATA
AAAACGTTAACTAA

Upstream 100 bases:

>100_bases
ACATTACTGCTTATTTATATAATGTCTATTCGTATTTTTCTGCTATTCTTGATAAAAAAAATTTATCACCCCTCAACAAA
TTAATAAAAGAGAGGCTTAA

Downstream 100 bases:

>100_bases
TTTAACAAAGAAGGATATCCCCAACCGTTTTCATTTTTTATCACTTTTTCTTCGGTTAAATATTGATACAGTGTTGGAGC
TAAAGAACCGTTCTCTTCAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MLNLKQLETFVWIAHLGSFRQAAKHLCTTQPAISTRIANLEETLNTALFYRDTGSISLTAKGRELLPLAEKLLSNADQLQ
VLANSAEAISGILRIGVSETVVHTWLPHYLALIHQNLPHLEVELIVDATINLRKELLARNIDIAILLGVVDEPNVVSQAI
CNYDLHWVASPALQQTQKNKVLNFAQWPLITYARNTSPYYEIERYFNTHNNQATRFYSASSLSASIRLAESGIGIAILPK
EVIHTSLQNNTLEIIEADWSPSPLQFSVAYIDTPVNLMTMESVKLTFEAVKQYKNVN

Sequences:

>Translated_297_residues
MLNLKQLETFVWIAHLGSFRQAAKHLCTTQPAISTRIANLEETLNTALFYRDTGSISLTAKGRELLPLAEKLLSNADQLQ
VLANSAEAISGILRIGVSETVVHTWLPHYLALIHQNLPHLEVELIVDATINLRKELLARNIDIAILLGVVDEPNVVSQAI
CNYDLHWVASPALQQTQKNKVLNFAQWPLITYARNTSPYYEIERYFNTHNNQATRFYSASSLSASIRLAESGIGIAILPK
EVIHTSLQNNTLEIIEADWSPSPLQFSVAYIDTPVNLMTMESVKLTFEAVKQYKNVN
>Mature_297_residues
MLNLKQLETFVWIAHLGSFRQAAKHLCTTQPAISTRIANLEETLNTALFYRDTGSISLTAKGRELLPLAEKLLSNADQLQ
VLANSAEAISGILRIGVSETVVHTWLPHYLALIHQNLPHLEVELIVDATINLRKELLARNIDIAILLGVVDEPNVVSQAI
CNYDLHWVASPALQQTQKNKVLNFAQWPLITYARNTSPYYEIERYFNTHNNQATRFYSASSLSASIRLAESGIGIAILPK
EVIHTSLQNNTLEIIEADWSPSPLQFSVAYIDTPVNLMTMESVKLTFEAVKQYKNVN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=248, Percent_Identity=28.2258064516129, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788481, Length=255, Percent_Identity=26.2745098039216, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788297, Length=244, Percent_Identity=27.4590163934426, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790399, Length=146, Percent_Identity=32.8767123287671, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790208, Length=279, Percent_Identity=24.7311827956989, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=146, Percent_Identity=27.3972602739726, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788887, Length=244, Percent_Identity=23.7704918032787, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082132, Length=172, Percent_Identity=26.1627906976744, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790262, Length=247, Percent_Identity=24.2914979757085, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787128, Length=296, Percent_Identity=23.6486486486486, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786713, Length=74, Percent_Identity=47.2972972972973, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=22.9965156794425, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789639, Length=271, Percent_Identity=23.9852398523985, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787806, Length=252, Percent_Identity=19.8412698412698, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788626, Length=251, Percent_Identity=25.8964143426295, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33261; Mature: 33261

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLKQLETFVWIAHLGSFRQAAKHLCTTQPAISTRIANLEETLNTALFYRDTGSISLTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCEEEEE
KGRELLPLAEKLLSNADQLQVLANSAEAISGILRIGVSETVVHTWLPHYLALIHQNLPHL
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCE
EVELIVDATINLRKELLARNIDIAILLGVVDEPNVVSQAICNYDLHWVASPALQQTQKNK
EEEEEEECHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCCEEECHHHHHHHHHH
VLNFAQWPLITYARNTSPYYEIERYFNTHNNQATRFYSASSLSASIRLAESGIGIAILPK
CCCHHCCCEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCEEEECH
EVIHTSLQNNTLEIIEADWSPSPLQFSVAYIDTPVNLMTMESVKLTFEAVKQYKNVN
HHHHHHHCCCEEEEEECCCCCCCEEEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLNLKQLETFVWIAHLGSFRQAAKHLCTTQPAISTRIANLEETLNTALFYRDTGSISLTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCEEEEE
KGRELLPLAEKLLSNADQLQVLANSAEAISGILRIGVSETVVHTWLPHYLALIHQNLPHL
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCE
EVELIVDATINLRKELLARNIDIAILLGVVDEPNVVSQAICNYDLHWVASPALQQTQKNK
EEEEEEECHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCCEEECHHHHHHHHHH
VLNFAQWPLITYARNTSPYYEIERYFNTHNNQATRFYSASSLSASIRLAESGIGIAILPK
CCCHHCCCEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCEEEECH
EVIHTSLQNNTLEIIEADWSPSPLQFSVAYIDTPVNLMTMESVKLTFEAVKQYKNVN
HHHHHHHCCCEEEEEECCCCCCCEEEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA