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The map label for this gene is ybgJ [H]

Identifier: 59711982

GI number: 59711982

Start: 1521754

End: 1522482

Strand: Reverse

Name: ybgJ [H]

Synonym: VF_1375

Alternate gene names: 59711982

Gene position: 1522482-1521754 (Counterclockwise)

Preceding gene: 59711983

Following gene: 59711981

Centisome position: 52.54

GC content: 36.9

Gene sequence:

>729_bases
ATGAAAATATCCGCTGTCAATGAATCGACTTTGTTACTTACCTTTGCTGATAAAGTCAGTCCTGAAGTCGCTGATATGAT
TGCTGAATCAGTCACTCTTTTTACTCAAGAGATCGGTTCACTTATTGTCGATATTGTTCCTTCATACACATCTATATTAA
TCACATATGATACCTCTAGTGTAGATTTACGCCGCTTTATGATGCAGTTACATCAGTGTATACCTTCTGATTTACAGAAG
ATGCAATCGAGTAAGTCTACAGTAGAAATAGAACTGCCAGTCTATTATGGAAAAGAAGTGTCACTTGATGCTGATGAGAT
TTGTGACCACACAGGATTAAGTTTTGAAGAGGTGATATCAATACATTCATCTCAAACGTACCGAGTTTATGCCATAGGCT
TTGCTCCCGGATTTGCTTATTTAGGAAATACTGATTCTAGAATTCATGTCCCTAGAAAAAGCACACCACGTTTAATGGTG
CCAGCTGGAAGTTTAGCTATTGCAGAACAACAAACAGCTATATATCCAAAGTCATCACCTGGTGGTTGGCAAATAATAGG
AAGAACGCCTGTCAACCTTATTGATTTTAATCGTAAAAACTTAACCTTGTTTGAGATGGGAGCGAAAGTAACATTTGTTT
CAATTTCTCGTGAAACCTATATTGAAATGGGTGGTGAATTACCTTGTGAATCAGAATCTATGAGGGATACAAATGACTTT
ACGAATTAA

Upstream 100 bases:

>100_bases
AAATACACGCAGATACATTGTGTATTCATGGGGACGGACCATTTGCTGTCTCTACGGCTGAATATCTACGAAAAAAATTA
AAATCAAAGTCGGAGTCATG

Downstream 100 bases:

>100_bases
TAGCACAGGCCCATTAGCACTACTTCAAGATAAAGGACGATTTGGTCACCAGTCCGTTGGTGTAACTCCGGGTGGTCCAA
TGGATGAACATGCGTTTGAT

Product: allophanate hydrolase subunit 1

Products: NA

Alternate protein names: Sporulation inhibitor kipI [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKISAVNESTLLLTFADKVSPEVADMIAESVTLFTQEIGSLIVDIVPSYTSILITYDTSSVDLRRFMMQLHQCIPSDLQK
MQSSKSTVEIELPVYYGKEVSLDADEICDHTGLSFEEVISIHSSQTYRVYAIGFAPGFAYLGNTDSRIHVPRKSTPRLMV
PAGSLAIAEQQTAIYPKSSPGGWQIIGRTPVNLIDFNRKNLTLFEMGAKVTFVSISRETYIEMGGELPCESESMRDTNDF
TN

Sequences:

>Translated_242_residues
MKISAVNESTLLLTFADKVSPEVADMIAESVTLFTQEIGSLIVDIVPSYTSILITYDTSSVDLRRFMMQLHQCIPSDLQK
MQSSKSTVEIELPVYYGKEVSLDADEICDHTGLSFEEVISIHSSQTYRVYAIGFAPGFAYLGNTDSRIHVPRKSTPRLMV
PAGSLAIAEQQTAIYPKSSPGGWQIIGRTPVNLIDFNRKNLTLFEMGAKVTFVSISRETYIEMGGELPCESESMRDTNDF
TN
>Mature_242_residues
MKISAVNESTLLLTFADKVSPEVADMIAESVTLFTQEIGSLIVDIVPSYTSILITYDTSSVDLRRFMMQLHQCIPSDLQK
MQSSKSTVEIELPVYYGKEVSLDADEICDHTGLSFEEVISIHSSQTYRVYAIGFAPGFAYLGNTDSRIHVPRKSTPRLMV
PAGSLAIAEQQTAIYPKSSPGGWQIIGRTPVNLIDFNRKNLTLFEMGAKVTFVSISRETYIEMGGELPCESESMRDTNDF
TN

Specific function: Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase

COG id: COG2049

COG function: function code E; Allophanate hydrolase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786929, Length=141, Percent_Identity=42.5531914893617, Blast_Score=124, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003833
- InterPro:   IPR020899
- InterPro:   IPR010016
- InterPro:   IPR002130 [H]

Pfam domain/function: PF02682 AHS1 [H]

EC number: NA

Molecular weight: Translated: 26857; Mature: 26857

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISAVNESTLLLTFADKVSPEVADMIAESVTLFTQEIGSLIVDIVPSYTSILITYDTSS
CEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
VDLRRFMMQLHQCIPSDLQKMQSSKSTVEIELPVYYGKEVSLDADEICDHTGLSFEEVIS
HHHHHHHHHHHHHCHHHHHHHHCCCCEEEEEEEEEECCEECCCHHHHHCCCCCCHHHHHH
IHSSQTYRVYAIGFAPGFAYLGNTDSRIHVPRKSTPRLMVPAGSLAIAEQQTAIYPKSSP
HCCCCEEEEEEEEECCCEEEECCCCCEEECCCCCCCEEEECCCCEEEECCCEEECCCCCC
GGWQIIGRTPVNLIDFNRKNLTLFEMGAKVTFVSISRETYIEMGGELPCESESMRDTNDF
CCEEEEECCCCEEEECCCCCEEEEECCCEEEEEEECCHHHHHCCCCCCCCCCCCCCCCCC
TN
CC
>Mature Secondary Structure
MKISAVNESTLLLTFADKVSPEVADMIAESVTLFTQEIGSLIVDIVPSYTSILITYDTSS
CEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
VDLRRFMMQLHQCIPSDLQKMQSSKSTVEIELPVYYGKEVSLDADEICDHTGLSFEEVIS
HHHHHHHHHHHHHCHHHHHHHHCCCCEEEEEEEEEECCEECCCHHHHHCCCCCCHHHHHH
IHSSQTYRVYAIGFAPGFAYLGNTDSRIHVPRKSTPRLMVPAGSLAIAEQQTAIYPKSSP
HCCCCEEEEEEEEECCCEEEECCCCCEEECCCCCCCEEEECCCCEEEECCCEEECCCCCC
GGWQIIGRTPVNLIDFNRKNLTLFEMGAKVTFVSISRETYIEMGGELPCESESMRDTNDF
CCEEEEECCCCEEEECCCCCEEEEECCCEEEEEEECCHHHHHCCCCCCCCCCCCCCCCCC
TN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]