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The map label for this gene is hlyB [H]

Identifier: 59711976

GI number: 59711976

Start: 1514881

End: 1516914

Strand: Reverse

Name: hlyB [H]

Synonym: VF_1369

Alternate gene names: 59711976

Gene position: 1516914-1514881 (Counterclockwise)

Preceding gene: 59711977

Following gene: 59711975

Centisome position: 52.35

GC content: 41.49

Gene sequence:

>2034_bases
ATGTGCGTCGAATGTTATATGATGCGTTGTGTAACTATTTGTTTCAATTATGAGATATATGTCAGTAAACCGTGGTTGGC
TAGGTTCGTTTTACTGTTTCCGCATATATCACCAATTAAAATTATTAGAAGTAGACGTATTATGCATCTAACATTAAAAA
CTAAACTCGTGTTGACGAGTCTTGCGCTTATTGTATTAACCATTGTATCTCTTGGTACTTTCTCGTATCAGACAATGAAA
ACTCAAGCCTGGGATGCCATTCAAAGTGAAAGTGGAAATACAGCGAAGGCTTATAGCTTAGGTATTGGCGATTGGTTTAA
AGGTCGCCAAGATGCGATTGTTGCTATGAAAGAAGCAATAGAGCGAGATCCTAACTTAGATATGGTCGCTCATTTAAAGC
AAACATTCACATCAGGTGGTTTTGGCTTAAGTTATTACGGTGACGAAAATGCTGTGATGCAACGCCAAGATCCATCGTTA
AACAAAGCCGGTTATGATCCGCGAACTCGTGGCTGGTACAAAGAAACATTGGCAGCTAATAAGGGTATAACAACAAAGCC
TTATGTTAGTCATACGATGCAAGCTCTTGTTGTTACCTTAACTGAACCCGTTCGTGAAAATGGGCGTATTGTCGGTGTGA
CTGCATCTAACTTGGCATTAGGGGCATTAATTGATGATGTTCTTGATATTCCAGTTCCAGGTAATGGTTATGCCATGCTA
CTGGATGTGAGTAATAAAATCGTTGTTGCTCACCCAAATGAGAAAATGGCGTTAAAACCAATTTCAGAACTTGGTAATGG
ATTCGATGCTAACAATTTAAGTAATGAAATTGCATCTGATGGTTTTTTCTTTACCGAAGAGAATGGGAAAGAGAAAGCGG
TCATGATCACGGCGGTTCCAAATACCAATTGGGCAATTACCTTGGTGATGGACAAAGAGACATTAGAAGCGCCATTAAAT
TCAATGCTTTTTGAATTGCTGTCCATTGGAGTGTTAATCTTACTGTTTGTATCTATGTTCACAGGATGGCTTGTTACTCG
TCAATTACGAGAACTTGGCACAGTTTCGGATGCATTAGCGGATATCGCAAATGGCGAAGGCGACCTTACGGTTCGTATTA
ATGTTAAATCGGATGATGAAGTGGGTAAGTTAGCAGATAACTTCAACCAGTTCGTATCACGCTTGCATGCGATGGCATCA
AATTTACGTGAAATAACTTTTGAGTTAAATCGCTCAGCAGCAGAAAGTGCAGATTCAGCCGTTCAACGCAGTCAAAATAT
TCGTCATCAACAAGATGAAATCACCATGGTTGCTACTGCAGTAACTGAGATGGCGAGTGCGACACAAGAGATTGCTGGAA
ATGCTGAAAACACTGCTAAATCGGCAGAGCAAGCGGTGGGATTAACACAAACAGGTCACGATCAAGCAAATCAAAGCCAA
GCATCTATCGGAAATCTTGCTCGTGAGGTAAATAGTGCGGTGGGCATCATTGAAGATCTTAACGGACACGCACTCAAAAT
CAGTTCAATTTTGGCCACCATTCGTTCGATAGCCGAGCAAACAAACTTACTCGCATTAAACGCAGCAATCGAAGCGGCAC
GTGCTGGCGAACAAGGTCGAGGATTTGCGGTTGTGGCTGATGAAGTTCGAGTTTTGTCTCAACGAACCCATACTTCAACA
GAAGAGATTCAAGCCATGATAGAAACGCTTCAATCAACAACACAAGAAGCGGTTTCAGTCATGTCGGACAGTCATCACTT
GGCAGAAACAAGCGTAAAAGATGTCGATGAAGCGGGAGTCAGTATTGGGAATATTGCTGCGCAAATTAATGTGATTAGCG
ATATGGCGACTCAAATTGCTTCTGCTGCAGAAGAGCAGTCAAGTGTTACGGCTGAAATTAGTCGAAATACAGAAGGGGTT
CAGGAAGTAGCAAACCAAATGGCGCATGAGGCTGAGACCGCAGCACTGCAGGCTGAGTCATTAAAATCGTTAGCTGATTC
ATTAGAAGAAGAAATTAAACGATATAAACTGTAA

Upstream 100 bases:

>100_bases
AAGAATAATGTTAATTGTTCTTAGGTTTTTTTATGCCTGAAGAAATTATAAGAGATTTAACGAGATAGACAGTTAAGTTT
GTGAAAATGAACACATTTTG

Downstream 100 bases:

>100_bases
CTTATTAATAAACAGTAAAAAACCGTCCAATAGTGACGGTTTTTTTACGTCAAAAAAGTGTGATTTTGTTTCCAATGTTG
TGTAAGGCAACACCTTGTAA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MCVECYMMRCVTICFNYEIYVSKPWLARFVLLFPHISPIKIIRSRRIMHLTLKTKLVLTSLALIVLTIVSLGTFSYQTMK
TQAWDAIQSESGNTAKAYSLGIGDWFKGRQDAIVAMKEAIERDPNLDMVAHLKQTFTSGGFGLSYYGDENAVMQRQDPSL
NKAGYDPRTRGWYKETLAANKGITTKPYVSHTMQALVVTLTEPVRENGRIVGVTASNLALGALIDDVLDIPVPGNGYAML
LDVSNKIVVAHPNEKMALKPISELGNGFDANNLSNEIASDGFFFTEENGKEKAVMITAVPNTNWAITLVMDKETLEAPLN
SMLFELLSIGVLILLFVSMFTGWLVTRQLRELGTVSDALADIANGEGDLTVRINVKSDDEVGKLADNFNQFVSRLHAMAS
NLREITFELNRSAAESADSAVQRSQNIRHQQDEITMVATAVTEMASATQEIAGNAENTAKSAEQAVGLTQTGHDQANQSQ
ASIGNLAREVNSAVGIIEDLNGHALKISSILATIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLSQRTHTST
EEIQAMIETLQSTTQEAVSVMSDSHHLAETSVKDVDEAGVSIGNIAAQINVISDMATQIASAAEEQSSVTAEISRNTEGV
QEVANQMAHEAETAALQAESLKSLADSLEEEIKRYKL

Sequences:

>Translated_677_residues
MCVECYMMRCVTICFNYEIYVSKPWLARFVLLFPHISPIKIIRSRRIMHLTLKTKLVLTSLALIVLTIVSLGTFSYQTMK
TQAWDAIQSESGNTAKAYSLGIGDWFKGRQDAIVAMKEAIERDPNLDMVAHLKQTFTSGGFGLSYYGDENAVMQRQDPSL
NKAGYDPRTRGWYKETLAANKGITTKPYVSHTMQALVVTLTEPVRENGRIVGVTASNLALGALIDDVLDIPVPGNGYAML
LDVSNKIVVAHPNEKMALKPISELGNGFDANNLSNEIASDGFFFTEENGKEKAVMITAVPNTNWAITLVMDKETLEAPLN
SMLFELLSIGVLILLFVSMFTGWLVTRQLRELGTVSDALADIANGEGDLTVRINVKSDDEVGKLADNFNQFVSRLHAMAS
NLREITFELNRSAAESADSAVQRSQNIRHQQDEITMVATAVTEMASATQEIAGNAENTAKSAEQAVGLTQTGHDQANQSQ
ASIGNLAREVNSAVGIIEDLNGHALKISSILATIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLSQRTHTST
EEIQAMIETLQSTTQEAVSVMSDSHHLAETSVKDVDEAGVSIGNIAAQINVISDMATQIASAAEEQSSVTAEISRNTEGV
QEVANQMAHEAETAALQAESLKSLADSLEEEIKRYKL
>Mature_677_residues
MCVECYMMRCVTICFNYEIYVSKPWLARFVLLFPHISPIKIIRSRRIMHLTLKTKLVLTSLALIVLTIVSLGTFSYQTMK
TQAWDAIQSESGNTAKAYSLGIGDWFKGRQDAIVAMKEAIERDPNLDMVAHLKQTFTSGGFGLSYYGDENAVMQRQDPSL
NKAGYDPRTRGWYKETLAANKGITTKPYVSHTMQALVVTLTEPVRENGRIVGVTASNLALGALIDDVLDIPVPGNGYAML
LDVSNKIVVAHPNEKMALKPISELGNGFDANNLSNEIASDGFFFTEENGKEKAVMITAVPNTNWAITLVMDKETLEAPLN
SMLFELLSIGVLILLFVSMFTGWLVTRQLRELGTVSDALADIANGEGDLTVRINVKSDDEVGKLADNFNQFVSRLHAMAS
NLREITFELNRSAAESADSAVQRSQNIRHQQDEITMVATAVTEMASATQEIAGNAENTAKSAEQAVGLTQTGHDQANQSQ
ASIGNLAREVNSAVGIIEDLNGHALKISSILATIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLSQRTHTST
EEIQAMIETLQSTTQEAVSVMSDSHHLAETSVKDVDEAGVSIGNIAAQINVISDMATQIASAAEEQSSVTAEISRNTEGV
QEVANQMAHEAETAALQAESLKSLADSLEEEIKRYKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=354, Percent_Identity=29.9435028248588, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI2367378, Length=301, Percent_Identity=30.2325581395349, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI1788195, Length=261, Percent_Identity=32.183908045977, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788194, Length=377, Percent_Identity=26.525198938992, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1789453, Length=347, Percent_Identity=26.2247838616715, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73536; Mature: 73536

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCVECYMMRCVTICFNYEIYVSKPWLARFVLLFPHISPIKIIRSRRIMHLTLKTKLVLTS
CCHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCHHHHHHCCCEEEEHHHHHHHHHH
LALIVLTIVSLGTFSYQTMKTQAWDAIQSESGNTAKAYSLGIGDWFKGRQDAIVAMKEAI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCHHHHHHHHHHH
ERDPNLDMVAHLKQTFTSGGFGLSYYGDENAVMQRQDPSLNKAGYDPRTRGWYKETLAAN
HCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHCC
KGITTKPYVSHTMQALVVTLTEPVRENGRIVGVTASNLALGALIDDVLDIPVPGNGYAML
CCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCEEE
LDVSNKIVVAHPNEKMALKPISELGNGFDANNLSNEIASDGFFFTEENGKEKAVMITAVP
EECCCEEEEECCCCCCEECCHHHHCCCCCCCCCHHHHCCCCCEEECCCCCCEEEEEEEEC
NTNWAITLVMDKETLEAPLNSMLFELLSIGVLILLFVSMFTGWLVTRQLRELGTVSDALA
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIANGEGDLTVRINVKSDDEVGKLADNFNQFVSRLHAMASNLREITFELNRSAAESADSA
HHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VQRSQNIRHQQDEITMVATAVTEMASATQEIAGNAENTAKSAEQAVGLTQTGHDQANQSQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHH
ASIGNLAREVNSAVGIIEDLNGHALKISSILATIRSIAEQTNLLALNAAIEAARAGEQGR
HHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCC
GFAVVADEVRVLSQRTHTSTEEIQAMIETLQSTTQEAVSVMSDSHHLAETSVKDVDEAGV
CEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
SIGNIAAQINVISDMATQIASAAEEQSSVTAEISRNTEGVQEVANQMAHEAETAALQAES
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LKSLADSLEEEIKRYKL
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MCVECYMMRCVTICFNYEIYVSKPWLARFVLLFPHISPIKIIRSRRIMHLTLKTKLVLTS
CCHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCHHHHHHCCCEEEEHHHHHHHHHH
LALIVLTIVSLGTFSYQTMKTQAWDAIQSESGNTAKAYSLGIGDWFKGRQDAIVAMKEAI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCHHHHHHHHHHH
ERDPNLDMVAHLKQTFTSGGFGLSYYGDENAVMQRQDPSLNKAGYDPRTRGWYKETLAAN
HCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHCC
KGITTKPYVSHTMQALVVTLTEPVRENGRIVGVTASNLALGALIDDVLDIPVPGNGYAML
CCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCEEE
LDVSNKIVVAHPNEKMALKPISELGNGFDANNLSNEIASDGFFFTEENGKEKAVMITAVP
EECCCEEEEECCCCCCEECCHHHHCCCCCCCCCHHHHCCCCCEEECCCCCCEEEEEEEEC
NTNWAITLVMDKETLEAPLNSMLFELLSIGVLILLFVSMFTGWLVTRQLRELGTVSDALA
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIANGEGDLTVRINVKSDDEVGKLADNFNQFVSRLHAMASNLREITFELNRSAAESADSA
HHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VQRSQNIRHQQDEITMVATAVTEMASATQEIAGNAENTAKSAEQAVGLTQTGHDQANQSQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHH
ASIGNLAREVNSAVGIIEDLNGHALKISSILATIRSIAEQTNLLALNAAIEAARAGEQGR
HHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCC
GFAVVADEVRVLSQRTHTSTEEIQAMIETLQSTTQEAVSVMSDSHHLAETSVKDVDEAGV
CEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
SIGNIAAQINVISDMATQIASAAEEQSSVTAEISRNTEGVQEVANQMAHEAETAALQAES
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LKSLADSLEEEIKRYKL
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]