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The map label for this gene is prc [H]

Identifier: 59711887

GI number: 59711887

Start: 1422645

End: 1424666

Strand: Direct

Name: prc [H]

Synonym: VF_1280

Alternate gene names: 59711887

Gene position: 1422645-1424666 (Clockwise)

Preceding gene: 59711886

Following gene: 59711888

Centisome position: 49.1

GC content: 37.69

Gene sequence:

>2022_bases
ATGAATTGTCGATTTAGAGTCTCGCTGATTGCTGCTGGCGTTATGCTAGCAGCATCTGCACACGCACTTGAAGCTAAGGT
ATTAGACGCCAAGTTTTCCGAAACTGACTTACCAGTATTAGCCGCAGAAACGCAGCATGCCACTGCAAGTAAGCGCGTTA
CTTCTCGTTTTACACGTTCTCATTATAAGCATTTCTCATTAGATGATGACTTTTCAGTTGCCATTTATGAGCGATATTTA
GATATGCTTGATTATAATCGAAACGTGTTTATACAAGCAGACCTTGCTTCGTTCGCCCCATTATCAACTCAATTAGATGA
CCAATTAAAAGTTGGTGACACCAAAGCCGCTTTTGATATTTATAACTTATCTTTAAAACGTCGTTTTGAACGATATGTTT
ATGCATTGTCATTATTAGATAAAGAATTTGACTACACAGTAGACGAATCTATTGAACTTGATCGCTCTGAAGCGGCTTGG
CCAAAAGATGAAGCTGAGTTAAATGAACTTTGGCGTAAACGTGTTAAATATGATGCACTTAACTTGTCTATGGCAGGTAA
AGATTGGCCTGAAATCCAAGAGATGTTAGGCAAGCGTTATAATAATGCGCTTAAGCGTTTAACTCAAAGTCACAATGAAG
ATGCGTTCCAACTTTACATTAATGCGTTTGCACGTGAAGTTGATCCTCATACAAGTTATTTATCTCCACGTAATGCAGAA
CAATTCCAATCAGAAATGAATTTATCATTAGAGGGGATTGGTGCTGTGTTACAAGCAACGGATGACTATACTGTTATTCG
TTCTCTGGTTGCTGGTGGACCGGCATTAACAAGTAAAAAATTGTCTGAAGGCGACCGAATTATCGGTGTTGGCCAAGAAG
GTGAAAAAATTGTTGATGTTATTGGATGGCGTTTAGATGACGTTGTTCAACTTATTAAAGGACCAAAAGGGACAAAAGTG
AAGCTTGAGATCTTACCTGAAGGTAAGGATTCAAAAAGTCACACTGTCACAATTGTTCGAGATAAGATCCGTTTAGAAGA
CAGAGCAGTAAAATCTGAAGTGATTGAACAGAATGGCAAGAAAATTGGTGTACTAGAAGTACCAAGTTTCTATGTTGGTC
TTGCTGAAGATACGAAAAAAGAAATTGCTGAGCTAAAAGAGAAAGATATCTCAGGTATTATTGTTGATTTACGCAATAAT
GGTGGTGGGGCATTAACCGAAGCAACTGCGTTATCTGGCTTATTTATTACTGCAGGACCTGTTGTTCAGGTGCGTGATAG
TTATGGTCGAGTTAATGTAAATGCGGATACTGATGGTGAAATTTCATATACTGGCCCAATGACGGTTCTTGTTAATCGTT
ATAGTGCGTCAGCATCTGAGATTTTTGCTGCAGCAATGCAAGATTATGGTCGTGCGGTTATCTTGGGTGAAAACTCATTT
GGTAAAGGTACGGTTCAACAACATAGATCATTAAATCATATCTATGACTTGTTTGATAAACCACTTGGTCATGTTCAATA
CACAATTCAGAAATTCTACCGTATCAATGGTGGTAGTACTCAGAATTTAGGTGTTGTGCCTGATATTGCTTTCCCAACAG
CTATCGATCCAAAAGATACTGGTGAGAGTGTTGAAGATAACGCACTTCCATGGGATAGCATTAAAGCTGCTGATTATGCT
AAAACAAATCAAATCGCAGAAACGATTGAACCATTAGCGAAAAAACATGTTGAACGAATCAAAACCGATGAAGAGTTTGG
TTTTATTCAAGAAGACATTGCTCGTTATAAAGCTGAAAAAGACATTACTTCTATTTCATTGAATAAAAAAGTTCGTGAGA
AAGAGAGTGATGATGCAGATGCTCGTCGTCTAACTCGTGTAAATGAGAGACAAAAATTACTTGGAAAAGAAGAGTTTAAA
ACACTTGATGATATTCCAAAAGATTACGAAGTGCCTGATGCTTATTTAGATGAAGCGGTTTCAATTACGATTGATTTAGC
ACTAATGAATCAGAAAAAGTAA

Upstream 100 bases:

>100_bases
TTGAAATTAACAAGGATGATGTACGAATTCGCTTATCGAACGGCCTACAAATGGTTGTTAAAGCGGAGAATCTTCGTTCA
TAAAGGAGCACTCCCGACGC

Downstream 100 bases:

>100_bases
TCTCAATTTGAATTATTTTAAAACAGAAGTCATGATGGCTTCTGTTTTTTTATGTCTAAAAAACGGCAAATCATTGAATT
TACAACTAGGCTTAACATAG

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 673; Mature: 673

Protein sequence:

>673_residues
MNCRFRVSLIAAGVMLAASAHALEAKVLDAKFSETDLPVLAAETQHATASKRVTSRFTRSHYKHFSLDDDFSVAIYERYL
DMLDYNRNVFIQADLASFAPLSTQLDDQLKVGDTKAAFDIYNLSLKRRFERYVYALSLLDKEFDYTVDESIELDRSEAAW
PKDEAELNELWRKRVKYDALNLSMAGKDWPEIQEMLGKRYNNALKRLTQSHNEDAFQLYINAFAREVDPHTSYLSPRNAE
QFQSEMNLSLEGIGAVLQATDDYTVIRSLVAGGPALTSKKLSEGDRIIGVGQEGEKIVDVIGWRLDDVVQLIKGPKGTKV
KLEILPEGKDSKSHTVTIVRDKIRLEDRAVKSEVIEQNGKKIGVLEVPSFYVGLAEDTKKEIAELKEKDISGIIVDLRNN
GGGALTEATALSGLFITAGPVVQVRDSYGRVNVNADTDGEISYTGPMTVLVNRYSASASEIFAAAMQDYGRAVILGENSF
GKGTVQQHRSLNHIYDLFDKPLGHVQYTIQKFYRINGGSTQNLGVVPDIAFPTAIDPKDTGESVEDNALPWDSIKAADYA
KTNQIAETIEPLAKKHVERIKTDEEFGFIQEDIARYKAEKDITSISLNKKVREKESDDADARRLTRVNERQKLLGKEEFK
TLDDIPKDYEVPDAYLDEAVSITIDLALMNQKK

Sequences:

>Translated_673_residues
MNCRFRVSLIAAGVMLAASAHALEAKVLDAKFSETDLPVLAAETQHATASKRVTSRFTRSHYKHFSLDDDFSVAIYERYL
DMLDYNRNVFIQADLASFAPLSTQLDDQLKVGDTKAAFDIYNLSLKRRFERYVYALSLLDKEFDYTVDESIELDRSEAAW
PKDEAELNELWRKRVKYDALNLSMAGKDWPEIQEMLGKRYNNALKRLTQSHNEDAFQLYINAFAREVDPHTSYLSPRNAE
QFQSEMNLSLEGIGAVLQATDDYTVIRSLVAGGPALTSKKLSEGDRIIGVGQEGEKIVDVIGWRLDDVVQLIKGPKGTKV
KLEILPEGKDSKSHTVTIVRDKIRLEDRAVKSEVIEQNGKKIGVLEVPSFYVGLAEDTKKEIAELKEKDISGIIVDLRNN
GGGALTEATALSGLFITAGPVVQVRDSYGRVNVNADTDGEISYTGPMTVLVNRYSASASEIFAAAMQDYGRAVILGENSF
GKGTVQQHRSLNHIYDLFDKPLGHVQYTIQKFYRINGGSTQNLGVVPDIAFPTAIDPKDTGESVEDNALPWDSIKAADYA
KTNQIAETIEPLAKKHVERIKTDEEFGFIQEDIARYKAEKDITSISLNKKVREKESDDADARRLTRVNERQKLLGKEEFK
TLDDIPKDYEVPDAYLDEAVSITIDLALMNQKK
>Mature_673_residues
MNCRFRVSLIAAGVMLAASAHALEAKVLDAKFSETDLPVLAAETQHATASKRVTSRFTRSHYKHFSLDDDFSVAIYERYL
DMLDYNRNVFIQADLASFAPLSTQLDDQLKVGDTKAAFDIYNLSLKRRFERYVYALSLLDKEFDYTVDESIELDRSEAAW
PKDEAELNELWRKRVKYDALNLSMAGKDWPEIQEMLGKRYNNALKRLTQSHNEDAFQLYINAFAREVDPHTSYLSPRNAE
QFQSEMNLSLEGIGAVLQATDDYTVIRSLVAGGPALTSKKLSEGDRIIGVGQEGEKIVDVIGWRLDDVVQLIKGPKGTKV
KLEILPEGKDSKSHTVTIVRDKIRLEDRAVKSEVIEQNGKKIGVLEVPSFYVGLAEDTKKEIAELKEKDISGIIVDLRNN
GGGALTEATALSGLFITAGPVVQVRDSYGRVNVNADTDGEISYTGPMTVLVNRYSASASEIFAAAMQDYGRAVILGENSF
GKGTVQQHRSLNHIYDLFDKPLGHVQYTIQKFYRINGGSTQNLGVVPDIAFPTAIDPKDTGESVEDNALPWDSIKAADYA
KTNQIAETIEPLAKKHVERIKTDEEFGFIQEDIARYKAEKDITSISLNKKVREKESDDADARRLTRVNERQKLLGKEEFK
TLDDIPKDYEVPDAYLDEAVSITIDLALMNQKK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=679, Percent_Identity=57.879234167894, Blast_Score=796, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 75351; Mature: 75351

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCRFRVSLIAAGVMLAASAHALEAKVLDAKFSETDLPVLAAETQHATASKRVTSRFTRS
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHH
HYKHFSLDDDFSVAIYERYLDMLDYNRNVFIQADLASFAPLSTQLDDQLKVGDTKAAFDI
HCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCCCCCCEECCCCHHHHHH
YNLSLKRRFERYVYALSLLDKEFDYTVDESIELDRSEAAWPKDEAELNELWRKRVKYDAL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHE
NLSMAGKDWPEIQEMLGKRYNNALKRLTQSHNEDAFQLYINAFAREVDPHTSYLSPRNAE
EEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHH
QFQSEMNLSLEGIGAVLQATDDYTVIRSLVAGGPALTSKKLSEGDRIIGVGQEGEKIVDV
HHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHCCCCEEEEECCCCHHHHHH
IGWRLDDVVQLIKGPKGTKVKLEILPEGKDSKSHTVTIVRDKIRLEDRAVKSEVIEQNGK
HCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCC
KIGVLEVPSFYVGLAEDTKKEIAELKEKDISGIIVDLRNNGGGALTEATALSGLFITAGP
EEEEEECCHHEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCEEEECCC
VVQVRDSYGRVNVNADTDGEISYTGPMTVLVNRYSASASEIFAAAMQDYGRAVILGENSF
EEEEECCCCEEEECCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCC
GKGTVQQHRSLNHIYDLFDKPLGHVQYTIQKFYRINGGSTQNLGVVPDIAFPTAIDPKDT
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCC
GESVEDNALPWDSIKAADYAKTNQIAETIEPLAKKHVERIKTDEEFGFIQEDIARYKAEK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHC
DITSISLNKKVREKESDDADARRLTRVNERQKLLGKEEFKTLDDIPKDYEVPDAYLDEAV
CCCEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCHHHHCCCE
SITIDLALMNQKK
EEEEEEEECCCCC
>Mature Secondary Structure
MNCRFRVSLIAAGVMLAASAHALEAKVLDAKFSETDLPVLAAETQHATASKRVTSRFTRS
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHH
HYKHFSLDDDFSVAIYERYLDMLDYNRNVFIQADLASFAPLSTQLDDQLKVGDTKAAFDI
HCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCCCCCCEECCCCHHHHHH
YNLSLKRRFERYVYALSLLDKEFDYTVDESIELDRSEAAWPKDEAELNELWRKRVKYDAL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHE
NLSMAGKDWPEIQEMLGKRYNNALKRLTQSHNEDAFQLYINAFAREVDPHTSYLSPRNAE
EEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHH
QFQSEMNLSLEGIGAVLQATDDYTVIRSLVAGGPALTSKKLSEGDRIIGVGQEGEKIVDV
HHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHCCCCEEEEECCCCHHHHHH
IGWRLDDVVQLIKGPKGTKVKLEILPEGKDSKSHTVTIVRDKIRLEDRAVKSEVIEQNGK
HCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCC
KIGVLEVPSFYVGLAEDTKKEIAELKEKDISGIIVDLRNNGGGALTEATALSGLFITAGP
EEEEEECCHHEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCEEEECCC
VVQVRDSYGRVNVNADTDGEISYTGPMTVLVNRYSASASEIFAAAMQDYGRAVILGENSF
EEEEECCCCEEEECCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCC
GKGTVQQHRSLNHIYDLFDKPLGHVQYTIQKFYRINGGSTQNLGVVPDIAFPTAIDPKDT
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCC
GESVEDNALPWDSIKAADYAKTNQIAETIEPLAKKHVERIKTDEEFGFIQEDIARYKAEK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHC
DITSISLNKKVREKESDDADARRLTRVNERQKLLGKEEFKTLDDIPKDYEVPDAYLDEAV
CCCEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCHHHHCCCE
SITIDLALMNQKK
EEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]