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The map label for this gene is ssnA [H]

Identifier: 59711871

GI number: 59711871

Start: 1404944

End: 1406380

Strand: Direct

Name: ssnA [H]

Synonym: VF_1264

Alternate gene names: 59711871

Gene position: 1404944-1406380 (Clockwise)

Preceding gene: 59711870

Following gene: 59711872

Centisome position: 48.49

GC content: 40.43

Gene sequence:

>1437_bases
ATGAAGCTTAAAAGCTTGGTATTGAGTGTTAGCGCTGTCTTGCTATCTGGTTGTGGAACAATGGCAAAACAACAAGAATA
TAATGCAGATTTGATCATTAATAACGGACAAGTGTTAACCGTCAACGCCGATATGCAAGTGATTGATGATGGTGTCGTGG
TGGTTAAAAACGATAAAATAATTGCTGTTGGTGACGAAAAACTACTAGAGCAATATTATGCACCAAAAAACATTGATGCT
AATGACGGTATTGTGATGCCAGGAATGATTAATGCTCACAACCATCTTCCGATGATCGCATTTCGTGGTTTAGGTGAAGA
AGGCATTTCTAATCGATTATTTGCTTATTTTTTCCCGTTAGAAGCACAAAAGTTAAGCCGTGAGCTGATTTATAATGCCA
CTAAGCTTGGTGCTATCGACTTAGCCCAGAGTGGCGTTACCACTTATGCTGATATGTATTATCACATGGATGAAATGGCT
AAAGCGACCAAAGAGGTTGGGTTAAGAGCCGTACTTGGTGAAACGGTTATTAAGTTCCCTGTGGTGGATGCAAAACAACC
GTATGGTGGAATTCAATATGCCAAGCCATTTATTGAAGAGTATCAAAATGATCCGTTAATTACGCCAGCTTATGCACCTC
ATGCCGTGTATACGGTAAGTAAAGAAAAGCTTCAAGAGATCAATCAGCTTTCAGAAGATTACGATGTACCTGTTTTAATC
CATGTTGCTGAGTTTCCAAATGAAGAGGCAAGAATTAAAGATCCAACTAAAGCGACATCTCCTGTTGAGTATCTAGAAGA
GATTGGTGTACTGGACGAGCGTATGGTGATTGCTCACGGTATTCATTTGTCCCAACATGATCAAGCGTTATTAAAACAAG
CGGATGCGGGAGTGGTTTATAACCCAATGGCGAATGTGAAAGGGGCAACAGGCATTGCTCCTGCTTGGGATATGTTTCGT
GCGGATATGCGAGTTGGTTTAGGAACGGATGGACCAATGAGTTCAAACCAAGTGGATTTGTGGCGCACCTTAAGTTATGC
CGCAAATATGCAGCGTTTAAAACACTCAGACAGAACCATTATGATCCCAGAACAAGTGATTGAAATGGCAACCATTGGTG
GTGCAAAAGCATTGCATATGGAGGATGAGATCGGCTCTTTAGAAGTCGGAAAGAAAGCGGATATCATTATTGTTGAAACT
CAATCAGCGAACATGATGCCAAGTTATGATCCATACGCAACATTGGTTTATCAAGCCAACCCAAGTAATGTGGATACAAC
GATTGTAAATGGCAAAGTGGTTATGGAACAGCGCCAGATGAAGACGATTCAATTAGATGATATTCGACAAAGTGTTGAAG
CGTTTGAATCAGATATCGCCGATTTTGCAAAAGAACTATCCAAAAAAGCGATAAAATCCAAAAGTTTAATGGATTAG

Upstream 100 bases:

>100_bases
ATCTCGTAATCGTTATATTTATCAATTAAATTAATTAAGAAGAAGCATTCTCCCCAATGCTTCTTTTTTTTATTTTCGGG
GGCATGATTAAGGTTTAGGA

Downstream 100 bases:

>100_bases
TTTTATACAAAAAGCCTGATTTTTAGATGTTGAGTCAGGCTTTAAAAGATTCTCATATTTTGGATAGAATGAGACGATCG
ATTCCCTTATTATTCGACCT

Product: chlorohydrolase/aminohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase 1 [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MKLKSLVLSVSAVLLSGCGTMAKQQEYNADLIINNGQVLTVNADMQVIDDGVVVVKNDKIIAVGDEKLLEQYYAPKNIDA
NDGIVMPGMINAHNHLPMIAFRGLGEEGISNRLFAYFFPLEAQKLSRELIYNATKLGAIDLAQSGVTTYADMYYHMDEMA
KATKEVGLRAVLGETVIKFPVVDAKQPYGGIQYAKPFIEEYQNDPLITPAYAPHAVYTVSKEKLQEINQLSEDYDVPVLI
HVAEFPNEEARIKDPTKATSPVEYLEEIGVLDERMVIAHGIHLSQHDQALLKQADAGVVYNPMANVKGATGIAPAWDMFR
ADMRVGLGTDGPMSSNQVDLWRTLSYAANMQRLKHSDRTIMIPEQVIEMATIGGAKALHMEDEIGSLEVGKKADIIIVET
QSANMMPSYDPYATLVYQANPSNVDTTIVNGKVVMEQRQMKTIQLDDIRQSVEAFESDIADFAKELSKKAIKSKSLMD

Sequences:

>Translated_478_residues
MKLKSLVLSVSAVLLSGCGTMAKQQEYNADLIINNGQVLTVNADMQVIDDGVVVVKNDKIIAVGDEKLLEQYYAPKNIDA
NDGIVMPGMINAHNHLPMIAFRGLGEEGISNRLFAYFFPLEAQKLSRELIYNATKLGAIDLAQSGVTTYADMYYHMDEMA
KATKEVGLRAVLGETVIKFPVVDAKQPYGGIQYAKPFIEEYQNDPLITPAYAPHAVYTVSKEKLQEINQLSEDYDVPVLI
HVAEFPNEEARIKDPTKATSPVEYLEEIGVLDERMVIAHGIHLSQHDQALLKQADAGVVYNPMANVKGATGIAPAWDMFR
ADMRVGLGTDGPMSSNQVDLWRTLSYAANMQRLKHSDRTIMIPEQVIEMATIGGAKALHMEDEIGSLEVGKKADIIIVET
QSANMMPSYDPYATLVYQANPSNVDTTIVNGKVVMEQRQMKTIQLDDIRQSVEAFESDIADFAKELSKKAIKSKSLMD
>Mature_478_residues
MKLKSLVLSVSAVLLSGCGTMAKQQEYNADLIINNGQVLTVNADMQVIDDGVVVVKNDKIIAVGDEKLLEQYYAPKNIDA
NDGIVMPGMINAHNHLPMIAFRGLGEEGISNRLFAYFFPLEAQKLSRELIYNATKLGAIDLAQSGVTTYADMYYHMDEMA
KATKEVGLRAVLGETVIKFPVVDAKQPYGGIQYAKPFIEEYQNDPLITPAYAPHAVYTVSKEKLQEINQLSEDYDVPVLI
HVAEFPNEEARIKDPTKATSPVEYLEEIGVLDERMVIAHGIHLSQHDQALLKQADAGVVYNPMANVKGATGIAPAWDMFR
ADMRVGLGTDGPMSSNQVDLWRTLSYAANMQRLKHSDRTIMIPEQVIEMATIGGAKALHMEDEIGSLEVGKKADIIIVET
QSANMMPSYDPYATLVYQANPSNVDTTIVNGKVVMEQRQMKTIQLDDIRQSVEAFESDIADFAKELSKKAIKSKSLMD

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=390, Percent_Identity=23.3333333333333, Blast_Score=99, Evalue=8e-21,
Organism=Escherichia coli, GI1789249, Length=407, Percent_Identity=23.3415233415233, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082177, Length=421, Percent_Identity=25.1781472684086, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17540282, Length=388, Percent_Identity=23.1958762886598, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319963, Length=347, Percent_Identity=25.6484149855908, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24643849, Length=389, Percent_Identity=25.4498714652956, Blast_Score=112, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 52795; Mature: 52795

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKSLVLSVSAVLLSGCGTMAKQQEYNADLIINNGQVLTVNADMQVIDDGVVVVKNDKI
CCHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEECCEEEEEECCEEEECCCEEEEECCEE
IAVGDEKLLEQYYAPKNIDANDGIVMPGMINAHNHLPMIAFRGLGEEGISNRLFAYFFPL
EEECCHHHHHHHCCCCCCCCCCCEECCCEECCCCCCCEEEECCCCCCCCCCCEEEEEECC
EAQKLSRELIYNATKLGAIDLAQSGVTTYADMYYHMDEMAKATKEVGLRAVLGETVIKFP
CHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VVDAKQPYGGIQYAKPFIEEYQNDPLITPAYAPHAVYTVSKEKLQEINQLSEDYDVPVLI
CCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCEEEEECHHHHHHHHHHHHCCCCCEEE
HVAEFPNEEARIKDPTKATSPVEYLEEIGVLDERMVIAHGIHLSQHDQALLKQADAGVVY
EEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCEEE
NPMANVKGATGIAPAWDMFRADMRVGLGTDGPMSSNQVDLWRTLSYAANMQRLKHSDRTI
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
MIPEQVIEMATIGGAKALHMEDEIGSLEVGKKADIIIVETQSANMMPSYDPYATLVYQAN
ECHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECC
PSNVDTTIVNGKVVMEQRQMKTIQLDDIRQSVEAFESDIADFAKELSKKAIKSKSLMD
CCCCCEEEECCEEEEEHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLKSLVLSVSAVLLSGCGTMAKQQEYNADLIINNGQVLTVNADMQVIDDGVVVVKNDKI
CCHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEECCEEEEEECCEEEECCCEEEEECCEE
IAVGDEKLLEQYYAPKNIDANDGIVMPGMINAHNHLPMIAFRGLGEEGISNRLFAYFFPL
EEECCHHHHHHHCCCCCCCCCCCEECCCEECCCCCCCEEEECCCCCCCCCCCEEEEEECC
EAQKLSRELIYNATKLGAIDLAQSGVTTYADMYYHMDEMAKATKEVGLRAVLGETVIKFP
CHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VVDAKQPYGGIQYAKPFIEEYQNDPLITPAYAPHAVYTVSKEKLQEINQLSEDYDVPVLI
CCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCEEEEECHHHHHHHHHHHHCCCCCEEE
HVAEFPNEEARIKDPTKATSPVEYLEEIGVLDERMVIAHGIHLSQHDQALLKQADAGVVY
EEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCEEE
NPMANVKGATGIAPAWDMFRADMRVGLGTDGPMSSNQVDLWRTLSYAANMQRLKHSDRTI
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
MIPEQVIEMATIGGAKALHMEDEIGSLEVGKKADIIIVETQSANMMPSYDPYATLVYQAN
ECHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECC
PSNVDTTIVNGKVVMEQRQMKTIQLDDIRQSVEAFESDIADFAKELSKKAIKSKSLMD
CCCCCEEEECCEEEEEHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA