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The map label for this gene is cpdP [H]

Identifier: 59711863

GI number: 59711863

Start: 1397914

End: 1398906

Strand: Direct

Name: cpdP [H]

Synonym: VF_1256

Alternate gene names: 59711863

Gene position: 1397914-1398906 (Clockwise)

Preceding gene: 59711859

Following gene: 59711865

Centisome position: 48.24

GC content: 36.35

Gene sequence:

>993_bases
ATGTTTAAAAATAAATTAGCAGTGTTATTTACGTGTTTGTCTGTTTTTTCTTTTTCGGCTCAATCTGGGAGTTTTGATAC
CGTTACGTTAGGGAGTAAAGGTGGGATCCAAGATGGTAATTTAACGGCTTTTTTAATTAAAAGTGAGGCGGATTCTAATT
TTGTTATGCTTGATGCAGGCTCTGTTGTTAATGGATTAATTGTTTCAGAGCAGAAAGGAGCGTTTAAAGATATTACCGTG
CCAGACAGTTCTCCTTACACCAAAGTAGGTTACCTATTAAAGGATAAGATTAAGGGTTACTTTATCAGCCATGCTCATTT
AGATCATGTTGCCGGTTTAATTATCTCTTCTCCTGATGACAGTAAAAAACCGATATATGGATTAGCAGCGACAAATAAAG
ATCTCATGAAGAATTACTTTAATTGGTCAGCATGGCCTAATTTTGGTAACAAAGGTGAAGGCTTTAAACTGAACAAATAC
AATTATGTGGATCTTCAACCGGGCGTTTGGAGTCCGATAGCTGAAACAACAATGAGTGTGATGTCATTGCCTTTGTCTCA
TTCTGGTGGGCAATCTACGGTATTTATTCTAAAAGACAGTGAAGGGGATGTATTTGCTTATTTTGGTGATACAGGGCCAG
ATGAAGTAGAGAAAAGTTCGGCAATGAAAACGGCGTGGTCTGCTTTAGCTCCTTTTGTAAAACAAGGGAAGTTAAAGGGG
ATTATTATTGAAGTTTCTTTTACCAACGAAACCCCAGATAAATCTTTATTTGGACATTTAACGCCAAACTGGTTAGTTAA
AGAATTAAGTGTGCTTGAAGACATGAATGGCAAGGGTTCTTTAAATGATCTAAATGTAGCCATCAGTCACATCAAATACA
GCTTAAAGAACAGTGAAGATCCTAAAGTAATTATTAAAAAGCAGTTAGCAGAAGCAAATGACTTAGGTGTAAATTTCATT
TTTCCTGAGCAAGGTGATTCACTGCAGTTTTAA

Upstream 100 bases:

>100_bases
CCTTCTTATTAATAGTCTTAAATATTTAATACATCATTCATTTATCTCATTGTATTATCTGATTGAGCACAAGGGTGTGC
AGTATTATTTAAGGTTGGAT

Downstream 100 bases:

>100_bases
AAAAGTTATTGTAAAAATGGATATGGTCAATACAAAGACCATATCCACTCCACGCATTTGTTTTTTATCTCTTAAATCGT
CGTCTCTATTTTTTTAAGTA

Product: 3',5'-cyclic-nucleotide phosphodiesterase

Products: NA

Alternate protein names: 3':5'-CNP; PDEase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MFKNKLAVLFTCLSVFSFSAQSGSFDTVTLGSKGGIQDGNLTAFLIKSEADSNFVMLDAGSVVNGLIVSEQKGAFKDITV
PDSSPYTKVGYLLKDKIKGYFISHAHLDHVAGLIISSPDDSKKPIYGLAATNKDLMKNYFNWSAWPNFGNKGEGFKLNKY
NYVDLQPGVWSPIAETTMSVMSLPLSHSGGQSTVFILKDSEGDVFAYFGDTGPDEVEKSSAMKTAWSALAPFVKQGKLKG
IIIEVSFTNETPDKSLFGHLTPNWLVKELSVLEDMNGKGSLNDLNVAISHIKYSLKNSEDPKVIIKKQLAEANDLGVNFI
FPEQGDSLQF

Sequences:

>Translated_330_residues
MFKNKLAVLFTCLSVFSFSAQSGSFDTVTLGSKGGIQDGNLTAFLIKSEADSNFVMLDAGSVVNGLIVSEQKGAFKDITV
PDSSPYTKVGYLLKDKIKGYFISHAHLDHVAGLIISSPDDSKKPIYGLAATNKDLMKNYFNWSAWPNFGNKGEGFKLNKY
NYVDLQPGVWSPIAETTMSVMSLPLSHSGGQSTVFILKDSEGDVFAYFGDTGPDEVEKSSAMKTAWSALAPFVKQGKLKG
IIIEVSFTNETPDKSLFGHLTPNWLVKELSVLEDMNGKGSLNDLNVAISHIKYSLKNSEDPKVIIKKQLAEANDLGVNFI
FPEQGDSLQF
>Mature_330_residues
MFKNKLAVLFTCLSVFSFSAQSGSFDTVTLGSKGGIQDGNLTAFLIKSEADSNFVMLDAGSVVNGLIVSEQKGAFKDITV
PDSSPYTKVGYLLKDKIKGYFISHAHLDHVAGLIISSPDDSKKPIYGLAATNKDLMKNYFNWSAWPNFGNKGEGFKLNKY
NYVDLQPGVWSPIAETTMSVMSLPLSHSGGQSTVFILKDSEGDVFAYFGDTGPDEVEKSSAMKTAWSALAPFVKQGKLKG
IIIEVSFTNETPDKSLFGHLTPNWLVKELSVLEDMNGKGSLNDLNVAISHIKYSLKNSEDPKVIIKKQLAEANDLGVNFI
FPEQGDSLQF

Specific function: Seems to allow the organism to grow on cAMP [H]

COG id: COG5212

COG function: function code T; Low-affinity cAMP phosphodiesterase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cAMP phosphodiesterase class-II family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321189, Length=255, Percent_Identity=30.9803921568627, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR000396 [H]

Pfam domain/function: PF02112 PDEase_II [H]

EC number: =3.1.4.17 [H]

Molecular weight: Translated: 35981; Mature: 35981

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00607 PDEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKNKLAVLFTCLSVFSFSAQSGSFDTVTLGSKGGIQDGNLTAFLIKSEADSNFVMLDAG
CCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEECC
SVVNGLIVSEQKGAFKDITVPDSSPYTKVGYLLKDKIKGYFISHAHLDHVAGLIISSPDD
CHHEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHEEEEECCCC
SKKPIYGLAATNKDLMKNYFNWSAWPNFGNKGEGFKLNKYNYVDLQPGVWSPIAETTMSV
CCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCEEECCEEEEEECCCCCCHHHHHHHHH
MSLPLSHSGGQSTVFILKDSEGDVFAYFGDTGPDEVEKSSAMKTAWSALAPFVKQGKLKG
HHCCCCCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IIIEVSFTNETPDKSLFGHLTPNWLVKELSVLEDMNGKGSLNDLNVAISHIKYSLKNSED
EEEEEEECCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHEEHHEEECCCCCC
PKVIIKKQLAEANDLGVNFIFPEQGDSLQF
CHHHHHHHHCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MFKNKLAVLFTCLSVFSFSAQSGSFDTVTLGSKGGIQDGNLTAFLIKSEADSNFVMLDAG
CCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEECC
SVVNGLIVSEQKGAFKDITVPDSSPYTKVGYLLKDKIKGYFISHAHLDHVAGLIISSPDD
CHHEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHEEEEECCCC
SKKPIYGLAATNKDLMKNYFNWSAWPNFGNKGEGFKLNKYNYVDLQPGVWSPIAETTMSV
CCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCEEECCEEEEEECCCCCCHHHHHHHHH
MSLPLSHSGGQSTVFILKDSEGDVFAYFGDTGPDEVEKSSAMKTAWSALAPFVKQGKLKG
HHCCCCCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IIIEVSFTNETPDKSLFGHLTPNWLVKELSVLEDMNGKGSLNDLNVAISHIKYSLKNSED
EEEEEEECCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHEEHHEEECCCCCC
PKVIIKKQLAEANDLGVNFIFPEQGDSLQF
CHHHHHHHHCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8393003 [H]