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The map label for this gene is aroH [H]

Identifier: 59711848

GI number: 59711848

Start: 1380359

End: 1381411

Strand: Reverse

Name: aroH [H]

Synonym: VF_1241

Alternate gene names: 59711848

Gene position: 1381411-1380359 (Counterclockwise)

Preceding gene: 59711850

Following gene: 59711847

Centisome position: 47.68

GC content: 42.45

Gene sequence:

>1053_bases
ATGCCATTTCAAACAGATGAACTTCGTACTCAGCCTCTAGGCCCAATGCCAACGCCAGCTGAGCTTACGACTGCTCACCC
TATTACGGACGATGTTGCTGAACATATCGAGCAATCTCGTGCGCAGGTTGAAGCAATTTTAACTGGCAAAGATAAGCGCC
TTTTAGTTGTTGTGGGACCATGCTCTGTACACGATACAGAAGCAGCATTGGATTACGCACAACGCTTAGCAAACATTCAA
GAACAGTATAAAGATGAGCTTTTCATCGTTATGCGTACTTATTTTGAAAAACCGCGCACGATTGTGGGCTGGAAAGGCTT
AATTACAGATCCTAATTTAGATGGCAGCTATGCACTTGAAGCTGGCTTACATAAGGCTCGTAAACTACTCCTTGATATCA
ACAAACTGGGTTTAGCTACAGCGACTGAGTTTTTAGATATGATCACAGGTCAGTATATTGCTGATTTGATCACTTGGGGT
GCTGTTGGCGCTCGTACAACTGAATCTCAAATCCACCGTGAAATGGCATCTGCATTATCATGCCCTGTCGGTTTCAAAAA
CGGTACAAATGGTAATATTCAAATTGCTATGGATGCGATTCGTGCAGCGAAAGCTTCTCACTTTTTCTACTCGCCAGATA
AACAAGGCCGTATGACAGTTTACCGCACTGCGGGTAACCCATTTGGTCATGTGATCCTTCGTGGTGGTAATGATAAGCCT
AACTTCGATATCGATTCAGTGACAGATGCCTGTCAACGTTTAGCGGATGTTGATTTGCCTCCTCACCTAATCGTTGACTT
TAGTCATGCTAACTGTCAGAAAAAACACCGCCGCCAACTCGATGTAGCCAAAGATATTTGTGCTCAAATCGAATCTGGTA
GCAATAAAGTTGTTGGTATTATGGCTGAAAGCTTCATTGTTGAAGGCAACCAACCAATGACGGATTTAAATAACCTAACT
TATGGTCAATCTATTACAGACCCATGTTTAAGTTGGGAAGATACCGTGGCTATGTTAGACATGTTATCGAATACTATTAA
AACATCTCGTTAA

Upstream 100 bases:

>100_bases
TACTTATTGTGGCTAACAATAAAAGTTTTGGGTTTCATCCCCTCTCGTTTTCCGTTATCTTATCGGTGTGTATTAAAAAA
GAATTAACAGGCGAACTTTT

Downstream 100 bases:

>100_bases
TTTAAGGATTAAAACTATGCCTGCTTTTGATATTGTCTCTGAAGTTGATAATGTAGAACTGAAGAATGCGGTTGATAACG
CAACACGTGAACTTGCAACT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MPFQTDELRTQPLGPMPTPAELTTAHPITDDVAEHIEQSRAQVEAILTGKDKRLLVVVGPCSVHDTEAALDYAQRLANIQ
EQYKDELFIVMRTYFEKPRTIVGWKGLITDPNLDGSYALEAGLHKARKLLLDINKLGLATATEFLDMITGQYIADLITWG
AVGARTTESQIHREMASALSCPVGFKNGTNGNIQIAMDAIRAAKASHFFYSPDKQGRMTVYRTAGNPFGHVILRGGNDKP
NFDIDSVTDACQRLADVDLPPHLIVDFSHANCQKKHRRQLDVAKDICAQIESGSNKVVGIMAESFIVEGNQPMTDLNNLT
YGQSITDPCLSWEDTVAMLDMLSNTIKTSR

Sequences:

>Translated_350_residues
MPFQTDELRTQPLGPMPTPAELTTAHPITDDVAEHIEQSRAQVEAILTGKDKRLLVVVGPCSVHDTEAALDYAQRLANIQ
EQYKDELFIVMRTYFEKPRTIVGWKGLITDPNLDGSYALEAGLHKARKLLLDINKLGLATATEFLDMITGQYIADLITWG
AVGARTTESQIHREMASALSCPVGFKNGTNGNIQIAMDAIRAAKASHFFYSPDKQGRMTVYRTAGNPFGHVILRGGNDKP
NFDIDSVTDACQRLADVDLPPHLIVDFSHANCQKKHRRQLDVAKDICAQIESGSNKVVGIMAESFIVEGNQPMTDLNNLT
YGQSITDPCLSWEDTVAMLDMLSNTIKTSR
>Mature_349_residues
PFQTDELRTQPLGPMPTPAELTTAHPITDDVAEHIEQSRAQVEAILTGKDKRLLVVVGPCSVHDTEAALDYAQRLANIQE
QYKDELFIVMRTYFEKPRTIVGWKGLITDPNLDGSYALEAGLHKARKLLLDINKLGLATATEFLDMITGQYIADLITWGA
VGARTTESQIHREMASALSCPVGFKNGTNGNIQIAMDAIRAAKASHFFYSPDKQGRMTVYRTAGNPFGHVILRGGNDKPN
FDIDSVTDACQRLADVDLPPHLIVDFSHANCQKKHRRQLDVAKDICAQIESGSNKVVGIMAESFIVEGNQPMTDLNNLTY
GQSITDPCLSWEDTVAMLDMLSNTIKTSR

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787996, Length=345, Percent_Identity=63.4782608695652, Blast_Score=483, Evalue=1e-138,
Organism=Escherichia coli, GI1786969, Length=350, Percent_Identity=52.2857142857143, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1788953, Length=323, Percent_Identity=50.1547987616099, Blast_Score=329, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6319726, Length=347, Percent_Identity=44.956772334294, Blast_Score=308, Evalue=8e-85,
Organism=Saccharomyces cerevisiae, GI6320240, Length=352, Percent_Identity=42.8977272727273, Blast_Score=292, Evalue=5e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38615; Mature: 38484

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFQTDELRTQPLGPMPTPAELTTAHPITDDVAEHIEQSRAQVEAILTGKDKRLLVVVGP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEEECC
CSVHDTEAALDYAQRLANIQEQYKDELFIVMRTYFEKPRTIVGWKGLITDPNLDGSYALE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHH
AGLHKARKLLLDINKLGLATATEFLDMITGQYIADLITWGAVGARTTESQIHREMASALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
CPVGFKNGTNGNIQIAMDAIRAAKASHFFYSPDKQGRMTVYRTAGNPFGHVILRGGNDKP
CCCCCCCCCCCCEEEEHHHHHHHHHCCCEECCCCCCCEEEEEECCCCCEEEEEECCCCCC
NFDIDSVTDACQRLADVDLPPHLIVDFSHANCQKKHRRQLDVAKDICAQIESGSNKVVGI
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
MAESFIVEGNQPMTDLNNLTYGQSITDPCLSWEDTVAMLDMLSNTIKTSR
EEEEEEECCCCCCHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PFQTDELRTQPLGPMPTPAELTTAHPITDDVAEHIEQSRAQVEAILTGKDKRLLVVVGP
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEEECC
CSVHDTEAALDYAQRLANIQEQYKDELFIVMRTYFEKPRTIVGWKGLITDPNLDGSYALE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHH
AGLHKARKLLLDINKLGLATATEFLDMITGQYIADLITWGAVGARTTESQIHREMASALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
CPVGFKNGTNGNIQIAMDAIRAAKASHFFYSPDKQGRMTVYRTAGNPFGHVILRGGNDKP
CCCCCCCCCCCCEEEEHHHHHHHHHCCCEECCCCCCCEEEEEECCCCCEEEEEECCCCCC
NFDIDSVTDACQRLADVDLPPHLIVDFSHANCQKKHRRQLDVAKDICAQIESGSNKVVGI
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
MAESFIVEGNQPMTDLNNLTYGQSITDPCLSWEDTVAMLDMLSNTIKTSR
EEEEEEECCCCCCHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]