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The map label for this gene is pepF1 [H]

Identifier: 59711846

GI number: 59711846

Start: 1377994

End: 1379778

Strand: Direct

Name: pepF1 [H]

Synonym: VF_1239

Alternate gene names: 59711846

Gene position: 1377994-1379778 (Clockwise)

Preceding gene: 59711845

Following gene: 59711849

Centisome position: 47.56

GC content: 41.06

Gene sequence:

>1785_bases
ATGACAGCACCAAGCTGGGATCTTTCTATCGCATTCCAATCACTTCAAGATCCAAAATTAAAACAGACCATTTCTCAATT
AGAGCAACAGATTGCCGATTTCCCACAGTTAGACTCTGATGCCGCTGTATCGCAATTGCAGCACGCTATTTTAATGAAAG
AAGCTATCACTGTGAATCTTGCAACCGTGGCCAGCTATGCAAACTGCATTGCCTCGGTTGATTCTGCGAATAACGAAGCA
AAAGCCTTAGTTAATCACATGACAAAGCTAGGCTCTGCATTATCACAAGTATTCAGCCCATTTTTAGATAGTATCGTAAA
TTCACCTCTTGAACAGTTTGAGCAGATCATTTCAGAAAATGAAGAACTGAATGCACATCGTTTTCTGCTTGAAGAAGAGC
GCAAGCTTGTTGAAAACCGCTTAAGTGTAAAAGAAGAGCAATTGCTGTCTGCGATGAGTGTTGATGGTAAAAATGCATGG
GGTAAGTTATACGATAATATAACAGGCTCTATGAAGGTCACATTGGTACTGGCTGATGGTACAGAAGAAGTGATGGGACT
GTCACAAGCAGCAAGCATTTTATACGGCAGTGATACCTTACGTAGAGAACCTGCGTGGCGAGCGATTCAACAAGGTATGA
AACAGAATCAAGAGAGTTTCTCTGCCATCTTAAATGCGTTAGCGGGTTGGCGTTTAACGGAATATCAAAAGCGCAGTAAA
GAAAAATCGGTTCACTTTCTTGAGCCAAGTTTACATGGCAGCCGAATCGAACAAGCGACACTAGATAGTATGATGTCTGT
GGCGAAAAAGAATCGAGAAGTAGGACAAAAAGCTGGGCGATTAATGGCCAAAATGTTTGGAGCAGAGCAGCTAACGCCTT
GGGATCAACTTGCATCAATGCCACCATTAGTTGGAGAGGCTTCTAATTATAGTTTTGATGAAGCCATTGATATCATAAAA
GATGCATTTTCAGGTGTATCACAAGAGATGGCTGATTTTGTTGATGTAATGGTGAAAAACGGTTGGATAGATGCCGCACC
ACAAGAAACCAAACGTCTTGGTGCTTACTGCACAAAGTTTGCTGACTCACGTACGCCATTGGTCTTCATGACGTGGGGTG
ACAGCATGTCTGATGTGCTTACTCTTGCTCACGAACTCGGTCATGCGTTTCATAACTGGGTAATGCGAGATATGCCATTG
TGCACGACACGCTACCCAATGACACTTGCCGAGACAGCATCTATATTTGCTGAAAACGTAGTACGTGATGCTTTGCTTGC
AAAAGCGAAAACCAAAGAAGATAAAATTGAAATGTTATGGGAAGAGTTGTCATCAGCATTAGCATTGACGATTAATATTC
CAGTTCGTTATGAGTTTGAAAAAGCATTTTATGAGCAGCGTTCATCAAAAGAGCTTGGTGCTGAAGGTTTATCTGAGCTA
ATGCGTGTCACTTGGGAAGAGTGGTATGGTAACTCAATGAGTGAAGCAGATTCACTTTTCTGGGCAAGCAAATTGCATTT
CAGTATTCCTGAAGTAAGTTTCTACAACTACCCATACTTATTTGGTTATTTATTCAGTATTGGTGTGTACGCACAAAGAG
AAGCGAAAGGGGCTGATTTCTATGGAGATTATATTAATCTTTTAAGAGATACAGGAACCATGCGAGCTGAAGAAGTGGTA
CAAAAACACCTACAAATGGACTTAACACAAGAGACATTTTGGCAGCAGAGTTTGGATAGAGTTAGTAATCAAATTGACGA
ATTTGAACGTTTGATTAGTGAATAG

Upstream 100 bases:

>100_bases
AATATGCTTATCTGTCTTATAAATTGAGTCGATGAAGTGGAAGGCTTTACCTTGGACAGTAGCTTGATATGATAGAGAAA
AAATAAATAAGGGCACTATT

Downstream 100 bases:

>100_bases
AATTGAACAGTAAATAATAAAAAGCGCCTCACTGAAAAGTAGAGGCGCTTTTTTTATCTATCAAACTTAAACTAACAGTA
ATTAGTCACGGAAGTTAGTG

Product: oligoendopeptidase F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MTAPSWDLSIAFQSLQDPKLKQTISQLEQQIADFPQLDSDAAVSQLQHAILMKEAITVNLATVASYANCIASVDSANNEA
KALVNHMTKLGSALSQVFSPFLDSIVNSPLEQFEQIISENEELNAHRFLLEEERKLVENRLSVKEEQLLSAMSVDGKNAW
GKLYDNITGSMKVTLVLADGTEEVMGLSQAASILYGSDTLRREPAWRAIQQGMKQNQESFSAILNALAGWRLTEYQKRSK
EKSVHFLEPSLHGSRIEQATLDSMMSVAKKNREVGQKAGRLMAKMFGAEQLTPWDQLASMPPLVGEASNYSFDEAIDIIK
DAFSGVSQEMADFVDVMVKNGWIDAAPQETKRLGAYCTKFADSRTPLVFMTWGDSMSDVLTLAHELGHAFHNWVMRDMPL
CTTRYPMTLAETASIFAENVVRDALLAKAKTKEDKIEMLWEELSSALALTINIPVRYEFEKAFYEQRSSKELGAEGLSEL
MRVTWEEWYGNSMSEADSLFWASKLHFSIPEVSFYNYPYLFGYLFSIGVYAQREAKGADFYGDYINLLRDTGTMRAEEVV
QKHLQMDLTQETFWQQSLDRVSNQIDEFERLISE

Sequences:

>Translated_594_residues
MTAPSWDLSIAFQSLQDPKLKQTISQLEQQIADFPQLDSDAAVSQLQHAILMKEAITVNLATVASYANCIASVDSANNEA
KALVNHMTKLGSALSQVFSPFLDSIVNSPLEQFEQIISENEELNAHRFLLEEERKLVENRLSVKEEQLLSAMSVDGKNAW
GKLYDNITGSMKVTLVLADGTEEVMGLSQAASILYGSDTLRREPAWRAIQQGMKQNQESFSAILNALAGWRLTEYQKRSK
EKSVHFLEPSLHGSRIEQATLDSMMSVAKKNREVGQKAGRLMAKMFGAEQLTPWDQLASMPPLVGEASNYSFDEAIDIIK
DAFSGVSQEMADFVDVMVKNGWIDAAPQETKRLGAYCTKFADSRTPLVFMTWGDSMSDVLTLAHELGHAFHNWVMRDMPL
CTTRYPMTLAETASIFAENVVRDALLAKAKTKEDKIEMLWEELSSALALTINIPVRYEFEKAFYEQRSSKELGAEGLSEL
MRVTWEEWYGNSMSEADSLFWASKLHFSIPEVSFYNYPYLFGYLFSIGVYAQREAKGADFYGDYINLLRDTGTMRAEEVV
QKHLQMDLTQETFWQQSLDRVSNQIDEFERLISE
>Mature_593_residues
TAPSWDLSIAFQSLQDPKLKQTISQLEQQIADFPQLDSDAAVSQLQHAILMKEAITVNLATVASYANCIASVDSANNEAK
ALVNHMTKLGSALSQVFSPFLDSIVNSPLEQFEQIISENEELNAHRFLLEEERKLVENRLSVKEEQLLSAMSVDGKNAWG
KLYDNITGSMKVTLVLADGTEEVMGLSQAASILYGSDTLRREPAWRAIQQGMKQNQESFSAILNALAGWRLTEYQKRSKE
KSVHFLEPSLHGSRIEQATLDSMMSVAKKNREVGQKAGRLMAKMFGAEQLTPWDQLASMPPLVGEASNYSFDEAIDIIKD
AFSGVSQEMADFVDVMVKNGWIDAAPQETKRLGAYCTKFADSRTPLVFMTWGDSMSDVLTLAHELGHAFHNWVMRDMPLC
TTRYPMTLAETASIFAENVVRDALLAKAKTKEDKIEMLWEELSSALALTINIPVRYEFEKAFYEQRSSKELGAEGLSELM
RVTWEEWYGNSMSEADSLFWASKLHFSIPEVSFYNYPYLFGYLFSIGVYAQREAKGADFYGDYINLLRDTGTMRAEEVVQ
KHLQMDLTQETFWQQSLDRVSNQIDEFERLISE

Specific function: Hydrolyzes peptides containing between 7 and 17 amino acids with a rather wide specificity [H]

COG id: COG1164

COG function: function code E; Oligoendopeptidase F

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567
- InterPro:   IPR004438
- InterPro:   IPR013647 [H]

Pfam domain/function: PF01432 Peptidase_M3; PF08439 Peptidase_M3_N [H]

EC number: NA

Molecular weight: Translated: 67031; Mature: 66899

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPSWDLSIAFQSLQDPKLKQTISQLEQQIADFPQLDSDAAVSQLQHAILMKEAITVNL
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ATVASYANCIASVDSANNEAKALVNHMTKLGSALSQVFSPFLDSIVNSPLEQFEQIISEN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EELNAHRFLLEEERKLVENRLSVKEEQLLSAMSVDGKNAWGKLYDNITGSMKVTLVLADG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEEEECC
TEEVMGLSQAASILYGSDTLRREPAWRAIQQGMKQNQESFSAILNALAGWRLTEYQKRSK
HHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHH
EKSVHFLEPSLHGSRIEQATLDSMMSVAKKNREVGQKAGRLMAKMFGAEQLTPWDQLASM
HCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCC
PPLVGEASNYSFDEAIDIIKDAFSGVSQEMADFVDVMVKNGWIDAAPQETKRLGAYCTKF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
ADSRTPLVFMTWGDSMSDVLTLAHELGHAFHNWVMRDMPLCTTRYPMTLAETASIFAENV
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
VRDALLAKAKTKEDKIEMLWEELSSALALTINIPVRYEFEKAFYEQRSSKELGAEGLSEL
HHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEECCEEEHHHHHHHHHHHHHHHCHHHHHHH
MRVTWEEWYGNSMSEADSLFWASKLHFSIPEVSFYNYPYLFGYLFSIGVYAQREAKGADF
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCH
YGDYINLLRDTGTMRAEEVVQKHLQMDLTQETFWQQSLDRVSNQIDEFERLISE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAPSWDLSIAFQSLQDPKLKQTISQLEQQIADFPQLDSDAAVSQLQHAILMKEAITVNL
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ATVASYANCIASVDSANNEAKALVNHMTKLGSALSQVFSPFLDSIVNSPLEQFEQIISEN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EELNAHRFLLEEERKLVENRLSVKEEQLLSAMSVDGKNAWGKLYDNITGSMKVTLVLADG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEEEECC
TEEVMGLSQAASILYGSDTLRREPAWRAIQQGMKQNQESFSAILNALAGWRLTEYQKRSK
HHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHH
EKSVHFLEPSLHGSRIEQATLDSMMSVAKKNREVGQKAGRLMAKMFGAEQLTPWDQLASM
HCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCC
PPLVGEASNYSFDEAIDIIKDAFSGVSQEMADFVDVMVKNGWIDAAPQETKRLGAYCTKF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
ADSRTPLVFMTWGDSMSDVLTLAHELGHAFHNWVMRDMPLCTTRYPMTLAETASIFAENV
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
VRDALLAKAKTKEDKIEMLWEELSSALALTINIPVRYEFEKAFYEQRSSKELGAEGLSEL
HHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEECCEEEHHHHHHHHHHHHHHHCHHHHHHH
MRVTWEEWYGNSMSEADSLFWASKLHFSIPEVSFYNYPYLFGYLFSIGVYAQREAKGADF
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCH
YGDYINLLRDTGTMRAEEVVQKHLQMDLTQETFWQQSLDRVSNQIDEFERLISE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7798200; 9209029 [H]