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The map label for this gene is astE [H]

Identifier: 59711845

GI number: 59711845

Start: 1376903

End: 1377895

Strand: Direct

Name: astE [H]

Synonym: VF_1238

Alternate gene names: 59711845

Gene position: 1376903-1377895 (Clockwise)

Preceding gene: 59711844

Following gene: 59711846

Centisome position: 47.52

GC content: 37.26

Gene sequence:

>993_bases
ATGGATCGCATTGCATTTATTAAAGACACACTGGATTTCTCTAAGCCAATAAAGAGCACAACTTGGTTATTAAGCAATGG
AACGCAAGTTAACCATTTAGCTAGAGGAATCATCGAAATTGTTCCTAAAAATCCATCAAGTAAAGCAATCGTTTTATCTT
CAGGTATTCATGGAAATGAAACATCACCAATTGAAATCCTTAATGACATAATCAATGATATTCAAGGTGGCCTGTTAGTA
TTGCAACATCCATGTTTGTTTATCTATGGACACCCAGCAGCAACGCATCAACATATTCGATTCATTGATACCAATTTAAA
CCGATTGTTTTCACACCACCAAGCACCAGACGATGCTATTCAAGAAGTCGCTATTGCTAATCAATTAATGTCTTCTGTTG
ATGATTTCTATGCTAAATATTCTGAAAAAGAAAAATGGCATTTAGATCTGCATTGTGCGATTAGGCGTTCTAAACATTAT
ACTTTTGCAATACATCCTTTTAATCGTCATTACCAACGCTCTGAACCATTACTTCAATTTTTAAAACAGAGTCAGATAGA
GGCGTGTTTATATTCAGACGCGCCGGCATCTACTTTTAGTTGGTACAGTGCAGAGCATCATGGAGCACATGCGGCAACGG
TTGAGCTAGGGAAGGTATCTCGAATGGGAGAGAATGATGTTTTGTTGCTGAGTGGTTTTATTCAAGAGTTAAAGCGATTT
ATTTCTTCTTCAGATACGAATGCTATGGAGCCAAGTAATAGAGAGATTGTTGAGTATCAAGTCACTCGAAGCATTATGAA
AAAAAGCGATGAATTTGAGTTCTCTTTTGCAGCGGATTTATCAAATTTTACCTATTTTGAAGAGGGCGAGTCATTAGCTC
TTGATGGTGTTGACCACTACAAAGCAAATAGTGGTGGTGAATCGGTTGTATTTCCTAACGCCAATGTAGAGATTGGCCAT
AGAGCGTGTTTGCTTGTACAAAAGTGTAAATAA

Upstream 100 bases:

>100_bases
TTCAGGTTGTTATCACATATTTGTTTTTAATTTGTTATTGTTTTGTTTTTGTAATGGTACAGTTTTTAGTATTAAGTTTT
ACTAAAAACAGGAAGTGCCG

Downstream 100 bases:

>100_bases
TATGCTTATCTGTCTTATAAATTGAGTCGATGAAGTGGAAGGCTTTACCTTGGACAGTAGCTTGATATGATAGAGAAAAA
ATAAATAAGGGCACTATTAT

Product: succinylglutamate desuccinylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MDRIAFIKDTLDFSKPIKSTTWLLSNGTQVNHLARGIIEIVPKNPSSKAIVLSSGIHGNETSPIEILNDIINDIQGGLLV
LQHPCLFIYGHPAATHQHIRFIDTNLNRLFSHHQAPDDAIQEVAIANQLMSSVDDFYAKYSEKEKWHLDLHCAIRRSKHY
TFAIHPFNRHYQRSEPLLQFLKQSQIEACLYSDAPASTFSWYSAEHHGAHAATVELGKVSRMGENDVLLLSGFIQELKRF
ISSSDTNAMEPSNREIVEYQVTRSIMKKSDEFEFSFAADLSNFTYFEEGESLALDGVDHYKANSGGESVVFPNANVEIGH
RACLLVQKCK

Sequences:

>Translated_330_residues
MDRIAFIKDTLDFSKPIKSTTWLLSNGTQVNHLARGIIEIVPKNPSSKAIVLSSGIHGNETSPIEILNDIINDIQGGLLV
LQHPCLFIYGHPAATHQHIRFIDTNLNRLFSHHQAPDDAIQEVAIANQLMSSVDDFYAKYSEKEKWHLDLHCAIRRSKHY
TFAIHPFNRHYQRSEPLLQFLKQSQIEACLYSDAPASTFSWYSAEHHGAHAATVELGKVSRMGENDVLLLSGFIQELKRF
ISSSDTNAMEPSNREIVEYQVTRSIMKKSDEFEFSFAADLSNFTYFEEGESLALDGVDHYKANSGGESVVFPNANVEIGH
RACLLVQKCK
>Mature_330_residues
MDRIAFIKDTLDFSKPIKSTTWLLSNGTQVNHLARGIIEIVPKNPSSKAIVLSSGIHGNETSPIEILNDIINDIQGGLLV
LQHPCLFIYGHPAATHQHIRFIDTNLNRLFSHHQAPDDAIQEVAIANQLMSSVDDFYAKYSEKEKWHLDLHCAIRRSKHY
TFAIHPFNRHYQRSEPLLQFLKQSQIEACLYSDAPASTFSWYSAEHHGAHAATVELGKVSRMGENDVLLLSGFIQELKRF
ISSSDTNAMEPSNREIVEYQVTRSIMKKSDEFEFSFAADLSNFTYFEEGESLALDGVDHYKANSGGESVVFPNANVEIGH
RACLLVQKCK

Specific function: Transforms N(2)-succinylglutamate into succinate and glutamate [H]

COG id: COG2988

COG function: function code E; Succinylglutamate desuccinylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788040, Length=323, Percent_Identity=34.0557275541796, Blast_Score=191, Evalue=7e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007036
- InterPro:   IPR016681 [H]

Pfam domain/function: PF04952 AstE_AspA [H]

EC number: =3.5.1.96 [H]

Molecular weight: Translated: 37190; Mature: 37190

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIAFIKDTLDFSKPIKSTTWLLSNGTQVNHLARGIIEIVPKNPSSKAIVLSSGIHGNE
CCCEEHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHEEECCCCCCCEEEEECCCCCCC
TSPIEILNDIINDIQGGLLVLQHPCLFIYGHPAATHQHIRFIDTNLNRLFSHHQAPDDAI
CCHHHHHHHHHHHHCCCEEEEECCEEEEECCCCCCCCEEEEEECCHHHHHHHCCCCHHHH
QEVAIANQLMSSVDDFYAKYSEKEKWHLDLHCAIRRSKHYTFAIHPFNRHYQRSEPLLQF
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEECCCHHCCCCCHHHHHH
LKQSQIEACLYSDAPASTFSWYSAEHHGAHAATVELGKVSRMGENDVLLLSGFIQELKRF
HHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEEHHHHHCCCCCCEEHHHHHHHHHHHH
ISSSDTNAMEPSNREIVEYQVTRSIMKKSDEFEFSFAADLSNFTYFEEGESLALDGVDHY
HCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCEEEECCCHHC
KANSGGESVVFPNANVEIGHRACLLVQKCK
CCCCCCCEEEECCCCEEECCCEEEEEECCC
>Mature Secondary Structure
MDRIAFIKDTLDFSKPIKSTTWLLSNGTQVNHLARGIIEIVPKNPSSKAIVLSSGIHGNE
CCCEEHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHEEECCCCCCCEEEEECCCCCCC
TSPIEILNDIINDIQGGLLVLQHPCLFIYGHPAATHQHIRFIDTNLNRLFSHHQAPDDAI
CCHHHHHHHHHHHHCCCEEEEECCEEEEECCCCCCCCEEEEEECCHHHHHHHCCCCHHHH
QEVAIANQLMSSVDDFYAKYSEKEKWHLDLHCAIRRSKHYTFAIHPFNRHYQRSEPLLQF
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEECCCHHCCCCCHHHHHH
LKQSQIEACLYSDAPASTFSWYSAEHHGAHAATVELGKVSRMGENDVLLLSGFIQELKRF
HHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEEHHHHHCCCCCCEEHHHHHHHHHHHH
ISSSDTNAMEPSNREIVEYQVTRSIMKKSDEFEFSFAADLSNFTYFEEGESLALDGVDHY
HCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCEEEECCCHHC
KANSGGESVVFPNANVEIGHRACLLVQKCK
CCCCCCCEEEECCCCEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA