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The map label for this gene is hinT [C]

Identifier: 59711741

GI number: 59711741

Start: 1257351

End: 1257701

Strand: Direct

Name: hinT [C]

Synonym: VF_1134

Alternate gene names: 59711741

Gene position: 1257351-1257701 (Clockwise)

Preceding gene: 59711739

Following gene: 59711742

Centisome position: 43.39

GC content: 39.03

Gene sequence:

>351_bases
ATGGCTGAAGAAACAATTTTTAGTAAGATTATTCGCAAAGAAATTCCTGCGGATGTGGTATATCAAGATGATTTAGTTAC
GGCTTTTCGCGATATTAATCCAAGAGCGCCAAGCCATGTATTGATCATTCCTAATAAATTGATCCCTACTACGAATGACG
TAGAACCAGAAGATGAATTGGTGATGGGACGTTTGTTTACTGTGGCTAGAAAAATTGCACAAGATGAAGGAATTGCTGAA
GATGGTTACCGTTTAATCGTCAATTGTAATCCTCATGGTGGTCAAGAAGTTTACCATATTCATATGCACCTAGTTGGCGG
TCGCCCTTTAGGTCCAATGCTACTAAGCTAA

Upstream 100 bases:

>100_bases
TTTTACTATTTCTCAAGTGATTGTTTTTGAGCTATTTGTAACGCATACTAAGTGAAAGTAAAAAATAAAATAGAATTCTG
GGTATTATTGGAGGCGCTTC

Downstream 100 bases:

>100_bases
TAAATATCATATAGAGGCTCCTGTTTTTGTGGAGCCTTACTTTTCCAACGATGAGTTTCTTATAATAATGAATTCAATAT
TGAAGAAATCCACCATAGTT

Product: purine nucleoside phosphoramidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 115

Protein sequence:

>116_residues
MAEETIFSKIIRKEIPADVVYQDDLVTAFRDINPRAPSHVLIIPNKLIPTTNDVEPEDELVMGRLFTVARKIAQDEGIAE
DGYRLIVNCNPHGGQEVYHIHMHLVGGRPLGPMLLS

Sequences:

>Translated_116_residues
MAEETIFSKIIRKEIPADVVYQDDLVTAFRDINPRAPSHVLIIPNKLIPTTNDVEPEDELVMGRLFTVARKIAQDEGIAE
DGYRLIVNCNPHGGQEVYHIHMHLVGGRPLGPMLLS
>Mature_115_residues
AEETIFSKIIRKEIPADVVYQDDLVTAFRDINPRAPSHVLIIPNKLIPTTNDVEPEDELVMGRLFTVARKIAQDEGIAED
GYRLIVNCNPHGGQEVYHIHMHLVGGRPLGPMLLS

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=107, Percent_Identity=49.5327102803738, Blast_Score=115, Evalue=6e-27,
Organism=Homo sapiens, GI14211923, Length=109, Percent_Identity=47.7064220183486, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787346, Length=114, Percent_Identity=78.9473684210526, Blast_Score=174, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17506713, Length=109, Percent_Identity=44.0366972477064, Blast_Score=108, Evalue=6e-25,
Organism=Drosophila melanogaster, GI28574010, Length=109, Percent_Identity=46.7889908256881, Blast_Score=115, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24581222, Length=109, Percent_Identity=46.7889908256881, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 12982; Mature: 12851

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEETIFSKIIRKEIPADVVYQDDLVTAFRDINPRAPSHVLIIPNKLIPTTNDVEPEDEL
CCHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHH
VMGRLFTVARKIAQDEGIAEDGYRLIVNCNPHGGQEVYHIHMHLVGGRPLGPMLLS
HHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
AEETIFSKIIRKEIPADVVYQDDLVTAFRDINPRAPSHVLIIPNKLIPTTNDVEPEDEL
CHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHH
VMGRLFTVARKIAQDEGIAEDGYRLIVNCNPHGGQEVYHIHMHLVGGRPLGPMLLS
HHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]