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The map label for this gene is lolE [C]

Identifier: 59711712

GI number: 59711712

Start: 1217900

End: 1219129

Strand: Direct

Name: lolE [C]

Synonym: VF_1105

Alternate gene names: 59711712

Gene position: 1217900-1219129 (Clockwise)

Preceding gene: 59711711

Following gene: 59711713

Centisome position: 42.03

GC content: 39.11

Gene sequence:

>1230_bases
ATGCTTATTAAATTAGCTTGGCGAAACCTATGGCGACAGAAAAGAAGAACGATATTAACGGCCTCTGCATTAGCCTTGGC
CTTATTACTTTCGTTGTTGATGCGTAGCATTCAAGAAGGGAGCTATACAGCAAATATCGAGAATGCCGCACGTTTATCAA
CTGGCCTTATTCAACTGCAAAATCCCGAATTTAAAGAAACGCAAAGTATTGATGATTTGTTACCAATGAGTGACGACTTC
ATCGCTCCCACTAAGCAACAACCTAATATCCAATTTACCTTACCTCGAATTGAAACGTTTTCACTTGCTGCCGCAAAAGA
TAAGTCCAAGGGTGTATTAGTTGTTGGTGTCGATCCTCAACCTGAAAATACCTATTCATCTTTGGCAGATAAAGTGGTGC
AAGGAGCGTATTTTACCGCAACGGATAAATCGGTATTGTTATCAGAAGGACTGGCGAGATATTTTCAGTTAAATGTAGGG
GATGAAATTGTTCTTTATGGGCAAGGTTATCGAGGGCAGACTGCAGCAGGCTTATATGTAATAAAAGGCATTGTTCACTT
TCCAATGCCAGATCTAAATAACCAATTAATCTACCTTCCGATTCAAGAAGCGGTTCAACTCTTTAGTACCGAGAATCAAG
TAACGTCATGGGTGTTGCATACACGTGATTTTTCTTTGTTACCACAAACGGTTGATAACCTACAAAAAGGGTATGGGCAA
GTAGTGTCTGTACGTCCGTGGAATGATCTTAGCCCTGAAATGGAACAGCAAATTCAAATCGATAGAGTGAGCGGTATTAT
CATGATGTACATTTTATATGGCATTGTGGGCTTTGGTTTGTTCGCCACATTATTAATGATGACGCTTGAAAGACAGCGCG
AATTTGGTGTGATGTTAGCGACTGGAATGGTTCGGTTTCGATTATTAAAGCTGTTAGTAATTGAATCTTTCTTTATTGGC
TTATTAGGTATTCTTTTAGGCTTAGTTATCGCTATTCCGGTTCTTGGTTATCTTTATATCAATCCAATTACATTAACGGG
TGAAACCGCCAAAGCGATGCTTGAAATGGGGTATGATCCTGTTATTCCAGTATTAATCAGTGGGTGGCTTTTTATAAACC
AAATGTTGATTGTTACAGGTTTACTGCTTTTATGCCTATTATATCCATTATGGCGTGTTTATCACCTCGATATTGTTACT
GCATTAAAAGGAGGTTCTCATGCTGCTTAA

Upstream 100 bases:

>100_bases
AATGATCACCCATAAGGCGCAGTTTAACTTCTTAATTAATGATGAATTCTTCTCTCAAATGCAAATGAAGGCATTACGAT
ACTAACTATAGGTGCTGAAT

Downstream 100 bases:

>100_bases
ATTAGCGTGGCGTAATGTGTGGCGCAATAAAATGAGAACCTCAATCATGCTGGGCGCTATGATCTTCGGTGTCGTAGGCG
TGATTTTAATGATGGGGTTC

Product: transporter

Products: NA

Alternate protein names: Permease Involved In Lipoprotein Release; ABC Transporter Permease Protein; ABC-Type Transport System Permease Component; Lipoprotein-Releasing System Permease Protein; ABC Transporter Permease; Permease Of ABC-Transporter System; Lipoprotein Releasing System Transmembrane Protein LolC; Lipoprotein Release ABC Transporter Permease; Permease Of ABC Transporter System

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MLIKLAWRNLWRQKRRTILTASALALALLLSLLMRSIQEGSYTANIENAARLSTGLIQLQNPEFKETQSIDDLLPMSDDF
IAPTKQQPNIQFTLPRIETFSLAAAKDKSKGVLVVGVDPQPENTYSSLADKVVQGAYFTATDKSVLLSEGLARYFQLNVG
DEIVLYGQGYRGQTAAGLYVIKGIVHFPMPDLNNQLIYLPIQEAVQLFSTENQVTSWVLHTRDFSLLPQTVDNLQKGYGQ
VVSVRPWNDLSPEMEQQIQIDRVSGIIMMYILYGIVGFGLFATLLMMTLERQREFGVMLATGMVRFRLLKLLVIESFFIG
LLGILLGLVIAIPVLGYLYINPITLTGETAKAMLEMGYDPVIPVLISGWLFINQMLIVTGLLLLCLLYPLWRVYHLDIVT
ALKGGSHAA

Sequences:

>Translated_409_residues
MLIKLAWRNLWRQKRRTILTASALALALLLSLLMRSIQEGSYTANIENAARLSTGLIQLQNPEFKETQSIDDLLPMSDDF
IAPTKQQPNIQFTLPRIETFSLAAAKDKSKGVLVVGVDPQPENTYSSLADKVVQGAYFTATDKSVLLSEGLARYFQLNVG
DEIVLYGQGYRGQTAAGLYVIKGIVHFPMPDLNNQLIYLPIQEAVQLFSTENQVTSWVLHTRDFSLLPQTVDNLQKGYGQ
VVSVRPWNDLSPEMEQQIQIDRVSGIIMMYILYGIVGFGLFATLLMMTLERQREFGVMLATGMVRFRLLKLLVIESFFIG
LLGILLGLVIAIPVLGYLYINPITLTGETAKAMLEMGYDPVIPVLISGWLFINQMLIVTGLLLLCLLYPLWRVYHLDIVT
ALKGGSHAA
>Mature_409_residues
MLIKLAWRNLWRQKRRTILTASALALALLLSLLMRSIQEGSYTANIENAARLSTGLIQLQNPEFKETQSIDDLLPMSDDF
IAPTKQQPNIQFTLPRIETFSLAAAKDKSKGVLVVGVDPQPENTYSSLADKVVQGAYFTATDKSVLLSEGLARYFQLNVG
DEIVLYGQGYRGQTAAGLYVIKGIVHFPMPDLNNQLIYLPIQEAVQLFSTENQVTSWVLHTRDFSLLPQTVDNLQKGYGQ
VVSVRPWNDLSPEMEQQIQIDRVSGIIMMYILYGIVGFGLFATLLMMTLERQREFGVMLATGMVRFRLLKLLVIESFFIG
LLGILLGLVIAIPVLGYLYINPITLTGETAKAMLEMGYDPVIPVLISGWLFINQMLIVTGLLLLCLLYPLWRVYHLDIVT
ALKGGSHAA

Specific function: Part Of An ATP-Dependent Transport System Lolcde Responsible For The Release Of Lipoproteins Targeted To The Outer Membrane From The Inner Membrane. Such A Release Is Dependent Of The Sorting-Signal (Absence Of An Asp At Position 2 Of The Mature Lipoprot

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45661; Mature: 45661

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKLAWRNLWRQKRRTILTASALALALLLSLLMRSIQEGSYTANIENAARLSTGLIQLQ
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHCEEEEC
NPEFKETQSIDDLLPMSDDFIAPTKQQPNIQFTLPRIETFSLAAAKDKSKGVLVVGVDPQ
CCCCHHHCCHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCEEEEECCCC
PENTYSSLADKVVQGAYFTATDKSVLLSEGLARYFQLNVGDEIVLYGQGYRGQTAAGLYV
CCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCHHHHHH
IKGIVHFPMPDLNNQLIYLPIQEAVQLFSTENQVTSWVLHTRDFSLLPQTVDNLQKGYGQ
HHHHHHCCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
VVSVRPWNDLSPEMEQQIQIDRVSGIIMMYILYGIVGFGLFATLLMMTLERQREFGVMLA
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGMVRFRLLKLLVIESFFIGLLGILLGLVIAIPVLGYLYINPITLTGETAKAMLEMGYDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHCCCCC
VIPVLISGWLFINQMLIVTGLLLLCLLYPLWRVYHLDIVTALKGGSHAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLIKLAWRNLWRQKRRTILTASALALALLLSLLMRSIQEGSYTANIENAARLSTGLIQLQ
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHCEEEEC
NPEFKETQSIDDLLPMSDDFIAPTKQQPNIQFTLPRIETFSLAAAKDKSKGVLVVGVDPQ
CCCCHHHCCHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCEEEEECCCC
PENTYSSLADKVVQGAYFTATDKSVLLSEGLARYFQLNVGDEIVLYGQGYRGQTAAGLYV
CCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCHHHHHH
IKGIVHFPMPDLNNQLIYLPIQEAVQLFSTENQVTSWVLHTRDFSLLPQTVDNLQKGYGQ
HHHHHHCCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
VVSVRPWNDLSPEMEQQIQIDRVSGIIMMYILYGIVGFGLFATLLMMTLERQREFGVMLA
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGMVRFRLLKLLVIESFFIGLLGILLGLVIAIPVLGYLYINPITLTGETAKAMLEMGYDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHCCCCC
VIPVLISGWLFINQMLIVTGLLLLCLLYPLWRVYHLDIVTALKGGSHAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA