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The map label for this gene is sdcS [H]

Identifier: 59711659

GI number: 59711659

Start: 1160935

End: 1162395

Strand: Direct

Name: sdcS [H]

Synonym: VF_1052

Alternate gene names: 59711659

Gene position: 1160935-1162395 (Clockwise)

Preceding gene: 59711658

Following gene: 59711660

Centisome position: 40.07

GC content: 38.4

Gene sequence:

>1461_bases
ATGGAATTCAACATTTATTGTTCTATGGAAGTCGGAAACGTTATGCGTCAATACATGAAGTATTTAATCCCAACAATTAT
TCCTCTCATCATTTTATTGATGCCATTGTCAGCCTTTCCATTTGAAGGCATGACCATAATCCAACAGCGTGTTATTGCTA
TATTTTTATTAGCAGCGCTATGTTGGGTATTTGAACCGATTCCAATTTATGCCACTTCGGTTGTGATCATCGTTTTAGAA
TTATTAATGGTATCAAATAAAGGTTTTTTCTTATTTAAGATGAACCAAGATTCACCTCAATTTGGTGAGTTGTTGAATTA
CAGCGACATCATGGCGACGTTTGCAAGCCCAATCATTATGCTGTTTTTAGGTGGTTTCTTTCTCGCAATGGCGGCAACGA
AATACCGTTTAGACGTTAACTTAGCACGTGTATTACTAAAGCCGTTTGGCAGTGATCCTAAATTCGTAATGTTAGGCTTA
ATGCTGATCACTGGTATTTTCTCAATGTTCATGTCAAATACGGCGACAACGGCGATGATGCTATCTATCTTAACACCTGT
TATTGCTGTATTTGGTCCTAAAGATCCAGGTCGTGTTGCTTTTGCCTTGTGTATTCCTATTGCAGCGAACATTGGTGGTA
TTGGTACACCAATTGGTACTCCTCCTAATGCAATCGCACTTAAATATTTAGTAGGTGATAATTTAATTACGTTTGGTGAA
TGGATGGTCTTTGGTGTGCCATTTGTTATTGTGATGATGGCGTTAGCATGGTTTTTAATTAACTATTTGTATCCTGCTAA
ACAAACATCCATGAACTTAAATATTAAAGGCAAATTCTTAAAAACGCCGAAAGCCATTACGGTTTATATCACGTTTGCAG
GGACGATTTTGTTATGGTTGATGGGATCAAGCCATGGCATGAATTCGTATACAGTTGCTTTAATTCCTGTAGCCATATTT
TCTATTACAGGGATCATAAACAAAGAAGATCTTAAGAAGATCTCATGGGATGTGTTATGGCTAGTTTCTGGTGGTATCGC
TCTAGGCCTTGCATTAGATAAAACGGGGTTAGCGAAACTGGTTGTTCATAGTATTCCTTTTGACTCTTATTCTCCTTATG
TTGTGCTATTTGGTGCTGCGTTCTTGTGTTTATTAATGGCAAACTTTATGTCGCACACTGCAACAGCAAACTTATTAATG
CCAATTATGGCAGCTCTTGGTACTTCAATGAGCTCGTTAACTCCGCTCGGTGGCGAACTTACGCTAATCTTAATTGTGAC
TTTTGCTGCATCTTTAGGTATGTCTTTGCCTATCAGTACGCCACCTAATGCGTTAGCACACGCAACAGGAAATGTAGAAA
GCAGCCAAATGGCGAAAACCGGTGTTATTTTAGGGATTGTCGGGGTTTTATTAAGTTTTGTTATGGTGTGGGTTCTTCAT
TCAGTAGGTCATATTGGATAG

Upstream 100 bases:

>100_bases
TTTTACGTAATATTTGTCACAAATAGTCATATTTTTAATTATTTCAAAATAATCTTTGATCTAACACGTTATACCGAATA
GCAGTAAAAGTAGATAATCG

Downstream 100 bases:

>100_bases
TTTATGAATCAAGAAAAATTACAGCGATTAATTGGAGCGTATTTTTCTCAACCTGAGCGTCGGGTGACGCTTCCTGCAGG
TGAAACACTACTTGAGCAAG

Product: divalent anion:sodium symporter family protein

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MEFNIYCSMEVGNVMRQYMKYLIPTIIPLIILLMPLSAFPFEGMTIIQQRVIAIFLLAALCWVFEPIPIYATSVVIIVLE
LLMVSNKGFFLFKMNQDSPQFGELLNYSDIMATFASPIIMLFLGGFFLAMAATKYRLDVNLARVLLKPFGSDPKFVMLGL
MLITGIFSMFMSNTATTAMMLSILTPVIAVFGPKDPGRVAFALCIPIAANIGGIGTPIGTPPNAIALKYLVGDNLITFGE
WMVFGVPFVIVMMALAWFLINYLYPAKQTSMNLNIKGKFLKTPKAITVYITFAGTILLWLMGSSHGMNSYTVALIPVAIF
SITGIINKEDLKKISWDVLWLVSGGIALGLALDKTGLAKLVVHSIPFDSYSPYVVLFGAAFLCLLMANFMSHTATANLLM
PIMAALGTSMSSLTPLGGELTLILIVTFAASLGMSLPISTPPNALAHATGNVESSQMAKTGVILGIVGVLLSFVMVWVLH
SVGHIG

Sequences:

>Translated_486_residues
MEFNIYCSMEVGNVMRQYMKYLIPTIIPLIILLMPLSAFPFEGMTIIQQRVIAIFLLAALCWVFEPIPIYATSVVIIVLE
LLMVSNKGFFLFKMNQDSPQFGELLNYSDIMATFASPIIMLFLGGFFLAMAATKYRLDVNLARVLLKPFGSDPKFVMLGL
MLITGIFSMFMSNTATTAMMLSILTPVIAVFGPKDPGRVAFALCIPIAANIGGIGTPIGTPPNAIALKYLVGDNLITFGE
WMVFGVPFVIVMMALAWFLINYLYPAKQTSMNLNIKGKFLKTPKAITVYITFAGTILLWLMGSSHGMNSYTVALIPVAIF
SITGIINKEDLKKISWDVLWLVSGGIALGLALDKTGLAKLVVHSIPFDSYSPYVVLFGAAFLCLLMANFMSHTATANLLM
PIMAALGTSMSSLTPLGGELTLILIVTFAASLGMSLPISTPPNALAHATGNVESSQMAKTGVILGIVGVLLSFVMVWVLH
SVGHIG
>Mature_486_residues
MEFNIYCSMEVGNVMRQYMKYLIPTIIPLIILLMPLSAFPFEGMTIIQQRVIAIFLLAALCWVFEPIPIYATSVVIIVLE
LLMVSNKGFFLFKMNQDSPQFGELLNYSDIMATFASPIIMLFLGGFFLAMAATKYRLDVNLARVLLKPFGSDPKFVMLGL
MLITGIFSMFMSNTATTAMMLSILTPVIAVFGPKDPGRVAFALCIPIAANIGGIGTPIGTPPNAIALKYLVGDNLITFGE
WMVFGVPFVIVMMALAWFLINYLYPAKQTSMNLNIKGKFLKTPKAITVYITFAGTILLWLMGSSHGMNSYTVALIPVAIF
SITGIINKEDLKKISWDVLWLVSGGIALGLALDKTGLAKLVVHSIPFDSYSPYVVLFGAAFLCLLMANFMSHTATANLLM
PIMAALGTSMSSLTPLGGELTLILIVTFAASLGMSLPISTPPNALAHATGNVESSQMAKTGVILGIVGVLLSFVMVWVLH
SVGHIG

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=538, Percent_Identity=26.3940520446097, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI301069349, Length=301, Percent_Identity=24.2524916943522, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI219802232, Length=468, Percent_Identity=24.5726495726496, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI31377715, Length=303, Percent_Identity=25.0825082508251, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI19923838, Length=331, Percent_Identity=23.2628398791541, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI4506979, Length=144, Percent_Identity=32.6388888888889, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI225637552, Length=144, Percent_Identity=32.6388888888889, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI225637549, Length=144, Percent_Identity=32.6388888888889, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1786829, Length=498, Percent_Identity=23.2931726907631, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32565804, Length=427, Percent_Identity=28.3372365339578, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71988385, Length=427, Percent_Identity=28.3372365339578, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71989118, Length=505, Percent_Identity=22.970297029703, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32564681, Length=532, Percent_Identity=24.2481203007519, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324340, Length=440, Percent_Identity=29.0909090909091, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6319885, Length=445, Percent_Identity=28.9887640449438, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6322263, Length=408, Percent_Identity=30.6372549019608, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI281366409, Length=529, Percent_Identity=23.4404536862004, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17737623, Length=529, Percent_Identity=23.4404536862004, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24666468, Length=529, Percent_Identity=23.4404536862004, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI45551633, Length=529, Percent_Identity=23.4404536862004, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281362116, Length=490, Percent_Identity=22.6530612244898, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281362114, Length=489, Percent_Identity=22.6993865030675, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281362112, Length=489, Percent_Identity=22.6993865030675, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 52623; Mature: 52623

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFNIYCSMEVGNVMRQYMKYLIPTIIPLIILLMPLSAFPFEGMTIIQQRVIAIFLLAAL
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
CWVFEPIPIYATSVVIIVLELLMVSNKGFFLFKMNQDSPQFGELLNYSDIMATFASPIIM
HHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCHHHHHHHHHHHHHH
LFLGGFFLAMAATKYRLDVNLARVLLKPFGSDPKFVMLGLMLITGIFSMFMSNTATTAMM
HHHHHHHHHHHHHHHEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
LSILTPVIAVFGPKDPGRVAFALCIPIAANIGGIGTPIGTPPNAIALKYLVGDNLITFGE
HHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCHHHHH
WMVFGVPFVIVMMALAWFLINYLYPAKQTSMNLNIKGKFLKTPKAITVYITFAGTILLWL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCEEEEEEEHHHHHHHHH
MGSSHGMNSYTVALIPVAIFSITGIINKEDLKKISWDVLWLVSGGIALGLALDKTGLAKL
HCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCEEEEEEECCCHHHHH
VVHSIPFDSYSPYVVLFGAAFLCLLMANFMSHTATANLLMPIMAALGTSMSSLTPLGGEL
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCH
TLILIVTFAASLGMSLPISTPPNALAHATGNVESSQMAKTGVILGIVGVLLSFVMVWVLH
HHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVGHIG
HHCCCC
>Mature Secondary Structure
MEFNIYCSMEVGNVMRQYMKYLIPTIIPLIILLMPLSAFPFEGMTIIQQRVIAIFLLAAL
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
CWVFEPIPIYATSVVIIVLELLMVSNKGFFLFKMNQDSPQFGELLNYSDIMATFASPIIM
HHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCHHHHHHHHHHHHHH
LFLGGFFLAMAATKYRLDVNLARVLLKPFGSDPKFVMLGLMLITGIFSMFMSNTATTAMM
HHHHHHHHHHHHHHHEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
LSILTPVIAVFGPKDPGRVAFALCIPIAANIGGIGTPIGTPPNAIALKYLVGDNLITFGE
HHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCHHHHH
WMVFGVPFVIVMMALAWFLINYLYPAKQTSMNLNIKGKFLKTPKAITVYITFAGTILLWL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCEEEEEEEHHHHHHHHH
MGSSHGMNSYTVALIPVAIFSITGIINKEDLKKISWDVLWLVSGGIALGLALDKTGLAKL
HCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCEEEEEEECCCHHHHH
VVHSIPFDSYSPYVVLFGAAFLCLLMANFMSHTATANLLMPIMAALGTSMSSLTPLGGEL
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCH
TLILIVTFAASLGMSLPISTPPNALAHATGNVESSQMAKTGVILGIVGVLLSFVMVWVLH
HHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVGHIG
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA