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The map label for this gene is sohB [H]

Identifier: 59711647

GI number: 59711647

Start: 1146376

End: 1147437

Strand: Direct

Name: sohB [H]

Synonym: VF_1040

Alternate gene names: 59711647

Gene position: 1146376-1147437 (Clockwise)

Preceding gene: 59711645

Following gene: 59711648

Centisome position: 39.56

GC content: 38.23

Gene sequence:

>1062_bases
TTGGAATTTTTGTTTGATTACGGTCTCTTTTTAGCAAAGATCGCCACCGTTGTTGTTTCTATTATTGCCATTTTAGTTGC
AGCTAAAGCAGTGGGTGGTAAATCGACTGGTGCGAAAGGTGAATTAGAGGTAACTAACTTAACTGAGCAGTATAAAGATA
CTGTTGTGGAGTTAGAACATCATTTATTTGATGATGCAGAGTTAAAAGCGCGAGCTAAGGCCGAAAAGAAAGCAGAAAAA
GAAACGGAAAAAGCAAAACAAAAAGAGATTAAGCAAGCTGCAAAATCTGGTGAGCTTGAATTAAAACGTGATGCCCGTTT
ATTTGTCTTAGATTTTAATGGCAGTATCGATGCGAAAGAAGTAGCAGCGCTACGTGAGGAAGTATCAGCTATCTTAGCGG
TTGCTATTGAAGGCGACGAAGTACTTTTACGTCTTGAAAGTGGTGGTGGTATGGTTCATGGTTATGGCCTTGCTTCATCT
CAACTTGATCGCTTACGTGATGCGAATATTAAATTAACGATTTCTGTTGATAAAGTTGCGGCATCAGGTGGTTATATGAT
GGCGTGTATTGGCGAAAAAATCATTGCTGCACCGTTTGCAATCGTTGGCTCGATTGGTGTTGTTGCTCAGTTGCCAAATT
TCAATAAATTATTGAAGAAAAATGATATTGAATTTGAGCAATTAACCGCTGGTGAATACAAACGTACCCTAACAATGTTT
GGCGAAAATAGCGATAAAGCACGTGAAAAATTCCAACTAGAATTGGAAGAAACTCATGTTTTATTTAAAGATTTTATTCG
TGAACATCGTTCAGAGCTAGATCTGGAAAAAGTAGCAACAGGCGAGCATTGGTTTGGTAAACAAGCGTTAGAGTTAGGTC
TAATTGATGAGATTCAAACGTCGGATGATTATTTAACAAAAGCGTGTAAAGATCGTGAAGTTTTAGCGATTCATTACGTT
CAAAAGAAAAAGTTAAGCGATAAAATTGCGGGGATTGCAGGTCAGTCTGCGGAGAACGTATTTATGCGTTTAATTAGCAA
AGGTCAGCGACCGATTGTTTAA

Upstream 100 bases:

>100_bases
ATGTAAAAATGCGCGTTTAGTGCGATTTATTATCATAATGTGAACTAACTTCGAGTTAAGTCGAGTACAATACACGAAAC
ATACTTAAGAGGGTATTACA

Downstream 100 bases:

>100_bases
TTTTTGATGCAAGAAAGCGCATTAATTTAGACCATATCTGTTCAGTGATTTACAGGATAGATATGACAAAAAAGGCTGAG
ATTTCAGTCTTATTTGAGAT

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MEFLFDYGLFLAKIATVVVSIIAILVAAKAVGGKSTGAKGELEVTNLTEQYKDTVVELEHHLFDDAELKARAKAEKKAEK
ETEKAKQKEIKQAAKSGELELKRDARLFVLDFNGSIDAKEVAALREEVSAILAVAIEGDEVLLRLESGGGMVHGYGLASS
QLDRLRDANIKLTISVDKVAASGGYMMACIGEKIIAAPFAIVGSIGVVAQLPNFNKLLKKNDIEFEQLTAGEYKRTLTMF
GENSDKAREKFQLELEETHVLFKDFIREHRSELDLEKVATGEHWFGKQALELGLIDEIQTSDDYLTKACKDREVLAIHYV
QKKKLSDKIAGIAGQSAENVFMRLISKGQRPIV

Sequences:

>Translated_353_residues
MEFLFDYGLFLAKIATVVVSIIAILVAAKAVGGKSTGAKGELEVTNLTEQYKDTVVELEHHLFDDAELKARAKAEKKAEK
ETEKAKQKEIKQAAKSGELELKRDARLFVLDFNGSIDAKEVAALREEVSAILAVAIEGDEVLLRLESGGGMVHGYGLASS
QLDRLRDANIKLTISVDKVAASGGYMMACIGEKIIAAPFAIVGSIGVVAQLPNFNKLLKKNDIEFEQLTAGEYKRTLTMF
GENSDKAREKFQLELEETHVLFKDFIREHRSELDLEKVATGEHWFGKQALELGLIDEIQTSDDYLTKACKDREVLAIHYV
QKKKLSDKIAGIAGQSAENVFMRLISKGQRPIV
>Mature_353_residues
MEFLFDYGLFLAKIATVVVSIIAILVAAKAVGGKSTGAKGELEVTNLTEQYKDTVVELEHHLFDDAELKARAKAEKKAEK
ETEKAKQKEIKQAAKSGELELKRDARLFVLDFNGSIDAKEVAALREEVSAILAVAIEGDEVLLRLESGGGMVHGYGLASS
QLDRLRDANIKLTISVDKVAASGGYMMACIGEKIIAAPFAIVGSIGVVAQLPNFNKLLKKNDIEFEQLTAGEYKRTLTMF
GENSDKAREKFQLELEETHVLFKDFIREHRSELDLEKVATGEHWFGKQALELGLIDEIQTSDDYLTKACKDREVLAIHYV
QKKKLSDKIAGIAGQSAENVFMRLISKGQRPIV

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=353, Percent_Identity=54.6742209631728, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1788064, Length=319, Percent_Identity=26.3322884012539, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 38959; Mature: 38959

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLFDYGLFLAKIATVVVSIIAILVAAKAVGGKSTGAKGELEVTNLTEQYKDTVVELEH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHH
HLFDDAELKARAKAEKKAEKETEKAKQKEIKQAAKSGELELKRDARLFVLDFNGSIDAKE
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCHHH
VAALREEVSAILAVAIEGDEVLLRLESGGGMVHGYGLASSQLDRLRDANIKLTISVDKVA
HHHHHHHHHHHHHEEEECCEEEEEECCCCCEEEECCCCHHHHHHHCCCCEEEEEEEEHEE
ASGGYMMACIGEKIIAAPFAIVGSIGVVAQLPNFNKLLKKNDIEFEQLTAGEYKRTLTMF
CCCCEEEEECCCHHHHHHHHHHHCCHHEEECCCHHHHHHCCCCCHHHHCCHHHHHHHEEE
GENSDKAREKFQLELEETHVLFKDFIREHRSELDLEKVATGEHWFGKQALELGLIDEIQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHCHHHHHHCCHHHHCC
SDDYLTKACKDREVLAIHYVQKKKLSDKIAGIAGQSAENVFMRLISKGQRPIV
CHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEFLFDYGLFLAKIATVVVSIIAILVAAKAVGGKSTGAKGELEVTNLTEQYKDTVVELEH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHH
HLFDDAELKARAKAEKKAEKETEKAKQKEIKQAAKSGELELKRDARLFVLDFNGSIDAKE
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCHHH
VAALREEVSAILAVAIEGDEVLLRLESGGGMVHGYGLASSQLDRLRDANIKLTISVDKVA
HHHHHHHHHHHHHEEEECCEEEEEECCCCCEEEECCCCHHHHHHHCCCCEEEEEEEEHEE
ASGGYMMACIGEKIIAAPFAIVGSIGVVAQLPNFNKLLKKNDIEFEQLTAGEYKRTLTMF
CCCCEEEEECCCHHHHHHHHHHHCCHHEEECCCHHHHHHCCCCCHHHHCCHHHHHHHEEE
GENSDKAREKFQLELEETHVLFKDFIREHRSELDLEKVATGEHWFGKQALELGLIDEIQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHCHHHHHHCCHHHHCC
SDDYLTKACKDREVLAIHYVQKKKLSDKIAGIAGQSAENVFMRLISKGQRPIV
CHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]