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The map label for this gene is nadA [H]

Identifier: 59711572

GI number: 59711572

Start: 1057779

End: 1058828

Strand: Direct

Name: nadA [H]

Synonym: VF_0965

Alternate gene names: 59711572

Gene position: 1057779-1058828 (Clockwise)

Preceding gene: 59711571

Following gene: 59711574

Centisome position: 36.51

GC content: 39.62

Gene sequence:

>1050_bases
ATGGGCCATATTCTAGATCACATCGATACCGTTTATCCTTTCCCTCCAAAGCCAATCGCATTAAGTGCGGAAGAGAAAGT
AGAATACATTTCTAAAATCAAACAATTACTTAGAGATAAAAATGCGGTATTAATTGCCCATTATTATACTGATCCTGAAA
TTCAAGCATTAGCTGAAGAGACTGGTGGTTTTGTTGGTGATTCACTTGAAATGGCTAAATTTGGTAATCGTCATGAAGCA
AAAACATTAGTGATTGCTGGTGTTCGTTTCATGGGAGAATCTGCAAAAATTCTAACGCCTGAAAAAACCATTCTGATGCC
GACATTAGAGGCAGAGTGCTCACTAGATTTAGGCTGTCCAGCAGACAAGTTTACTGAGTTTTGTGACGCGCACCCTGATC
ATACGGTTGTGGTTTACGCTAATACTTCTGCAGCAGTAAAAGCTCGAGCTGATTGGGTGGTAACATCAAGCATTGCTTTA
GAAATCGTAGAGCACCTAGATGATGAAGATAAAAAAATCATTTGGGGACCAGATCGTCATTTAGGCTCATATATTGCGAA
TAAAACTGGCGCAGATATGCTTCTATGGCAAGGTGAGTGTATTGTTCATGATGAATTCTCAGCAAAAGCTTTAAAAGATG
CTAAAGCACTTCACCCTGATGCTGCTGTGTTAGTTCACCCTGAATCACCAGCAAGTGTTGTTGAGTTAGCGGACGCTGTT
GGTTCTACAAGTCAATTAATCAAAGCAGCTAAAGAGCTACCACAACAAAAAATGATTGTTGCAACAGATAAAGGTATTTT
CTTTAAAATGCAGCAAATGGTGCCAGAGAAAGAATTACTTGAAGCACCAACTGCAGGTGCTGGCGCAACATGCCGTAGTT
GTGCTCACTGTCCTTGGATGGCTATGAATGGCTTAGTTGCTATTGAGAAGTCACTTCGAGAAGGTGGGTCTGAGCATGAG
ATTTTCTTAGATGAAGAAACACGTTTAAAATCTCTTATTCCATTAAATCGTATGTTAGATTTTGCTGAGCAATTAAACGC
AAATAGATAA

Upstream 100 bases:

>100_bases
AAAGGAGCCTAAGGCTCCTTTTTTATTTCCCCTAACTTGCTGACTAAATCATTAGGGGTATAATGCTCAAACTATTTGAA
AAAAGTTACTGAGCTGAGCA

Downstream 100 bases:

>100_bases
TGCGATAAATGTTTTATATAAAAATGGCGACCAGTGCGGTCGCCATTTTTGTAATTTTATTTTTGGACTTTATTTATTCG
TCGCGACTTGCTTCTGCTTC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MGHILDHIDTVYPFPPKPIALSAEEKVEYISKIKQLLRDKNAVLIAHYYTDPEIQALAEETGGFVGDSLEMAKFGNRHEA
KTLVIAGVRFMGESAKILTPEKTILMPTLEAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIAL
EIVEHLDDEDKKIIWGPDRHLGSYIANKTGADMLLWQGECIVHDEFSAKALKDAKALHPDAAVLVHPESPASVVELADAV
GSTSQLIKAAKELPQQKMIVATDKGIFFKMQQMVPEKELLEAPTAGAGATCRSCAHCPWMAMNGLVAIEKSLREGGSEHE
IFLDEETRLKSLIPLNRMLDFAEQLNANR

Sequences:

>Translated_349_residues
MGHILDHIDTVYPFPPKPIALSAEEKVEYISKIKQLLRDKNAVLIAHYYTDPEIQALAEETGGFVGDSLEMAKFGNRHEA
KTLVIAGVRFMGESAKILTPEKTILMPTLEAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIAL
EIVEHLDDEDKKIIWGPDRHLGSYIANKTGADMLLWQGECIVHDEFSAKALKDAKALHPDAAVLVHPESPASVVELADAV
GSTSQLIKAAKELPQQKMIVATDKGIFFKMQQMVPEKELLEAPTAGAGATCRSCAHCPWMAMNGLVAIEKSLREGGSEHE
IFLDEETRLKSLIPLNRMLDFAEQLNANR
>Mature_348_residues
GHILDHIDTVYPFPPKPIALSAEEKVEYISKIKQLLRDKNAVLIAHYYTDPEIQALAEETGGFVGDSLEMAKFGNRHEAK
TLVIAGVRFMGESAKILTPEKTILMPTLEAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALE
IVEHLDDEDKKIIWGPDRHLGSYIANKTGADMLLWQGECIVHDEFSAKALKDAKALHPDAAVLVHPESPASVVELADAVG
STSQLIKAAKELPQQKMIVATDKGIFFKMQQMVPEKELLEAPTAGAGATCRSCAHCPWMAMNGLVAIEKSLREGGSEHEI
FLDEETRLKSLIPLNRMLDFAEQLNANR

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=347, Percent_Identity=68.5878962536023, Blast_Score=519, Evalue=1e-148,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38297; Mature: 38166

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHILDHIDTVYPFPPKPIALSAEEKVEYISKIKQLLRDKNAVLIAHYYTDPEIQALAEE
CCCHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHH
TGGFVGDSLEMAKFGNRHEAKTLVIAGVRFMGESAKILTPEKTILMPTLEAECSLDLGCP
HCCCCCCCHHHHHCCCCCCCCEEEEEEHHHCCCCCEEECCCCEEEEECCCCCCCCCCCCC
ADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDDEDKKIIWGPDRH
HHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHCCCCCCEEEECCCHH
LGSYIANKTGADMLLWQGECIVHDEFSAKALKDAKALHPDAAVLVHPESPASVVELADAV
HHHHHHCCCCCCEEEECCCEEEECCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
GSTSQLIKAAKELPQQKMIVATDKGIFFKMQQMVPEKELLEAPTAGAGATCRSCAHCPWM
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCHHHHHCCCCCCCCCHHHHHCCCCHH
AMNGLVAIEKSLREGGSEHEIFLDEETRLKSLIPLNRMLDFAEQLNANR
HHCCHHHHHHHHHCCCCCCEEEECCHHHHHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GHILDHIDTVYPFPPKPIALSAEEKVEYISKIKQLLRDKNAVLIAHYYTDPEIQALAEE
CCHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHH
TGGFVGDSLEMAKFGNRHEAKTLVIAGVRFMGESAKILTPEKTILMPTLEAECSLDLGCP
HCCCCCCCHHHHHCCCCCCCCEEEEEEHHHCCCCCEEECCCCEEEEECCCCCCCCCCCCC
ADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDDEDKKIIWGPDRH
HHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHCCCCCCEEEECCCHH
LGSYIANKTGADMLLWQGECIVHDEFSAKALKDAKALHPDAAVLVHPESPASVVELADAV
HHHHHHCCCCCCEEEECCCEEEECCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
GSTSQLIKAAKELPQQKMIVATDKGIFFKMQQMVPEKELLEAPTAGAGATCRSCAHCPWM
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCHHHHHCCCCCCCCCHHHHHCCCCHH
AMNGLVAIEKSLREGGSEHEIFLDEETRLKSLIPLNRMLDFAEQLNANR
HHCCHHHHHHHHHCCCCCCEEEECCHHHHHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA