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The map label for this gene is tig [H]

Identifier: 59711402

GI number: 59711402

Start: 869840

End: 871138

Strand: Direct

Name: tig [H]

Synonym: VF_0795

Alternate gene names: 59711402

Gene position: 869840-871138 (Clockwise)

Preceding gene: 59711401

Following gene: 59711403

Centisome position: 30.02

GC content: 42.26

Gene sequence:

>1299_bases
ATGCAAGTTACCGTTGAAACTAAAGAAGGCCTAGAGCGCGTTCTAACTATCACTGTTCCAGCAGCAAACATTGAAGATGC
AGTATCTGCTGAGCTTCGTAATATCGCTAAAAATCGTCGCTTCGATGGCTTCCGTAAAGGTAAAGTGCCAATGAAGATGG
TTGCGAAAATGTATGGTCAAGCGGTACGCAATGACGTGATGGGTGAAGTTATGCAACGTCACTTCATCGAAGCTATCGTA
AAAGAGAAAATCAACCCAGCGGGTGCTCCAACTTTTACTCCAGTTGAATTTGCTGAAGGTAAAGATCTAGTTTTCACTGC
TTCTTTTGAAGTTTACCCAGAAGTTGCTCTTCAAGGTCTAGACAAAGTTGTTGTTGAAAAACCACAAGTTGAAGTTAAAG
ACGAAGACGTAGCAGAAATGCTAGAAACTCTACGTAAGCAACAATCTACTTGGGCTGACGCTGATATCGCTGCTGAAGAC
GGTACTCGCGCTACAATCAACTTTGTTGGTTCTATCGACGGTGAAGAGTTTGAAGGCGGTAAAGCTGAAAACTTCCCTCT
AGAAATGGGCCAAGGTCGTATGATCCCTGGTTTTGAAGATGGCATCAAAGGTAAGAAAGCTGGTGAAGAACTAACTATCG
ACGTTAACTTCCCTGAAGAATACCACGCAGAAAACCTAAAAGGTAAAGCTGCACAATTCGCTATCAAAGTAGTGAAAGTT
GAATCTCGTGAGCTTCCTGAGCTAAACGATGAGTTCGTTGCTAAGTTCGGCGCTGAAGGTGGTGTTGAAGGTCTTAAAGC
TGAAGTTCGTAAGAACATGGAGCGTGAACTAGCTCAAGCTGTTAAGAACAAGATCAAAGAACAAGCAATCAACGGTCTAG
TTGAGCAAAACAACATTGACGTACCTTCTGCTCTAATCGATCAAGAAGTTCAAGTTTTACGTCAACAAGCAGTTCAACGT
TTCGGTGGCAACGCTGACACAGCTCCTGAGCTTCCACGTGAACTATTTGAAGAACAAGCTAAACGTCGCGTAGTTGTAGG
TCTTCTTCTTGGTGAAGTTATCAAGTCTGAAGAACTAAAAGCTGATGATGAGAAAGTAAAAGCGCTTATCAACGAAATGG
CTTCTGCATACGAAGATCCAACAGAAGTTGTTGCTTACTACGAAGGCAACGAGCAAATGATGAACAACATGCGTAATGTT
GCTCTAGAAGAACAAGCTGTTGAAGCTATCCTAGCTAAAGCACAAGTTTCTGAAAAAGCATTTGGCTTTAACGAACTAAT
GAATCAACAACCTGCTTAA

Upstream 100 bases:

>100_bases
GTTGCGGTCTATTTTTATAGTCCCGTGACACAAGGATGCGACACGTTTTGTTTTGTCGCAAACTCAGAGAACCTGAGTCG
ATTTTGAGGTTTATATAAAC

Downstream 100 bases:

>100_bases
TTTCTAAATTAATTAAGTAGTTAGTTGACTTAGTTTCACAAGATCTGCTAATAATGGTCCGAATGAAGCGTCATTCGGAC
CATTTATTTTATAAGGGATA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MQVTVETKEGLERVLTITVPAANIEDAVSAELRNIAKNRRFDGFRKGKVPMKMVAKMYGQAVRNDVMGEVMQRHFIEAIV
KEKINPAGAPTFTPVEFAEGKDLVFTASFEVYPEVALQGLDKVVVEKPQVEVKDEDVAEMLETLRKQQSTWADADIAAED
GTRATINFVGSIDGEEFEGGKAENFPLEMGQGRMIPGFEDGIKGKKAGEELTIDVNFPEEYHAENLKGKAAQFAIKVVKV
ESRELPELNDEFVAKFGAEGGVEGLKAEVRKNMERELAQAVKNKIKEQAINGLVEQNNIDVPSALIDQEVQVLRQQAVQR
FGGNADTAPELPRELFEEQAKRRVVVGLLLGEVIKSEELKADDEKVKALINEMASAYEDPTEVVAYYEGNEQMMNNMRNV
ALEEQAVEAILAKAQVSEKAFGFNELMNQQPA

Sequences:

>Translated_432_residues
MQVTVETKEGLERVLTITVPAANIEDAVSAELRNIAKNRRFDGFRKGKVPMKMVAKMYGQAVRNDVMGEVMQRHFIEAIV
KEKINPAGAPTFTPVEFAEGKDLVFTASFEVYPEVALQGLDKVVVEKPQVEVKDEDVAEMLETLRKQQSTWADADIAAED
GTRATINFVGSIDGEEFEGGKAENFPLEMGQGRMIPGFEDGIKGKKAGEELTIDVNFPEEYHAENLKGKAAQFAIKVVKV
ESRELPELNDEFVAKFGAEGGVEGLKAEVRKNMERELAQAVKNKIKEQAINGLVEQNNIDVPSALIDQEVQVLRQQAVQR
FGGNADTAPELPRELFEEQAKRRVVVGLLLGEVIKSEELKADDEKVKALINEMASAYEDPTEVVAYYEGNEQMMNNMRNV
ALEEQAVEAILAKAQVSEKAFGFNELMNQQPA
>Mature_432_residues
MQVTVETKEGLERVLTITVPAANIEDAVSAELRNIAKNRRFDGFRKGKVPMKMVAKMYGQAVRNDVMGEVMQRHFIEAIV
KEKINPAGAPTFTPVEFAEGKDLVFTASFEVYPEVALQGLDKVVVEKPQVEVKDEDVAEMLETLRKQQSTWADADIAAED
GTRATINFVGSIDGEEFEGGKAENFPLEMGQGRMIPGFEDGIKGKKAGEELTIDVNFPEEYHAENLKGKAAQFAIKVVKV
ESRELPELNDEFVAKFGAEGGVEGLKAEVRKNMERELAQAVKNKIKEQAINGLVEQNNIDVPSALIDQEVQVLRQQAVQR
FGGNADTAPELPRELFEEQAKRRVVVGLLLGEVIKSEELKADDEKVKALINEMASAYEDPTEVVAYYEGNEQMMNNMRNV
ALEEQAVEAILAKAQVSEKAFGFNELMNQQPA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=431, Percent_Identity=68.9095127610209, Blast_Score=599, Evalue=1e-172,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 47865; Mature: 47865

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVTVETKEGLERVLTITVPAANIEDAVSAELRNIAKNRRFDGFRKGKVPMKMVAKMYGQ
CEEEECHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
AVRNDVMGEVMQRHFIEAIVKEKINPAGAPTFTPVEFAEGKDLVFTASFEVYPEVALQGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHH
DKVVVEKPQVEVKDEDVAEMLETLRKQQSTWADADIAAEDGTRATINFVGSIDGEEFEGG
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCC
KAENFPLEMGQGRMIPGFEDGIKGKKAGEELTIDVNFPEEYHAENLKGKAAQFAIKVVKV
CCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHEEEE
ESRELPELNDEFVAKFGAEGGVEGLKAEVRKNMERELAQAVKNKIKEQAINGLVEQNNID
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VPSALIDQEVQVLRQQAVQRFGGNADTAPELPRELFEEQAKRRVVVGLLLGEVIKSEELK
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ADDEKVKALINEMASAYEDPTEVVAYYEGNEQMMNNMRNVALEEQAVEAILAKAQVSEKA
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGFNELMNQQPA
CCHHHHHCCCCC
>Mature Secondary Structure
MQVTVETKEGLERVLTITVPAANIEDAVSAELRNIAKNRRFDGFRKGKVPMKMVAKMYGQ
CEEEECHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
AVRNDVMGEVMQRHFIEAIVKEKINPAGAPTFTPVEFAEGKDLVFTASFEVYPEVALQGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHH
DKVVVEKPQVEVKDEDVAEMLETLRKQQSTWADADIAAEDGTRATINFVGSIDGEEFEGG
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCC
KAENFPLEMGQGRMIPGFEDGIKGKKAGEELTIDVNFPEEYHAENLKGKAAQFAIKVVKV
CCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHEEEE
ESRELPELNDEFVAKFGAEGGVEGLKAEVRKNMERELAQAVKNKIKEQAINGLVEQNNID
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VPSALIDQEVQVLRQQAVQRFGGNADTAPELPRELFEEQAKRRVVVGLLLGEVIKSEELK
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ADDEKVKALINEMASAYEDPTEVVAYYEGNEQMMNNMRNVALEEQAVEAILAKAQVSEKA
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGFNELMNQQPA
CCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA