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The map label for this gene is yocR [H]

Identifier: 59711267

GI number: 59711267

Start: 724612

End: 725955

Strand: Direct

Name: yocR [H]

Synonym: VF_0660

Alternate gene names: 59711267

Gene position: 724612-725955 (Clockwise)

Preceding gene: 59711263

Following gene: 59711271

Centisome position: 25.01

GC content: 38.24

Gene sequence:

>1344_bases
ATGAGCAGTAATAGAGAAAGTTTTAGTTCACGATTAGGTTTTATATTGGCAGCAGCAGGGGCTGCGGTTGGCCTTGGTAA
CATTTGGGGCTTCCCTACTCAAGCGGCAAGTAATGGTGGTGGCGCCTTCTTACTTGTTTATTTAATTATGATCTTAGTTG
TTGCTTTTCCTATGTTGGTTGTAGAAATGGCCATTGGTCGTCACGGACAAGCAAACCCTGTTGATAGTATGCGTTCGTTG
ACTTCTAACCCATTAGGAAAGAAATTTGGTGCATTTGTTGGTTGGATTGGATTAAGTGTTCCTAGCGCAGTATTAATGTT
TTATAGCATTGTTGGTGGATGGTTAATCTGTTTTCTACTTGGTGCTATGGCAAATGTTGTTGGATTGAATGACGTTGCTG
AGTGGTTTAAAGGCTTTAGTATTGAGCGTAATCTATTAGGTACGATCCTTTTTTATGTATTAACTATTCTAATCGTACAA
GGTGGAATCAAAGACGGTATTGAGAAATGGTCAACTCGCTTGATGCCTGCATTATTCATATTATTTGGCTTATTGTTTGT
TTATATCATGCTGCAGCAAGGGGCTGTAGAAGGATTGAAGCACTACCTTATTCCTGATTTTGAAAAGGTGATGGATAAGA
AATTAATTTTAGCAGCAATGGGACAGGGCTTTTTCTCTCTGACTATTGGTGGTTGTTCAATGCTGATTTATGGCTCTTAT
TTAAGTAAGAAAGAGAACCTGCCTAAGATGGCTATGAATGTAACCTTAGTGGATACTGCTGTTGCTTTTATTGCTGGTCT
TGTTGTATGCCTGCAATGTTTGTTGCTATGCAAAAAGGCGTCAATTTATGCAGAGGACGGTTCGTTATTAAGTTCTGATA
CTTTAGTATTTACTGTATTACCTATGATGTTTGATAGCTTAGGTTTGTTTGGTGATTTATTTGCTATTGTTTTCTTTGCG
CTGTTAACGATCGCTGCTTTAACTTCGTCGATCTCTATGCTTGAGTGTTCAGTATCGTTAGTAAGTGAGCGATTTGAAAC
AAAAAGAACGCCAACAAGTTGGGTTTTAGGTTCATTAATTGCAGCATTCAGCGTTGTTATTGTATTTAATTTTGGTGAGC
TATTTGGTTTAGTTGCTATGATTGCAACTCAGTATTTACAGCCAATTGCAGCATTATTGTTCTGTGTGTTTGGTGGTTGG
GTATGGAGTCGTCATTCTAAAATTAAAGAACTTGAGCAGGGTTATCCTGAGTTCCAGCAAGGTTTCTTTGGTAAAATTTG
GCCTCTGTATGTGAAATTTGTGTGTCCTATTTTGGTTATCACGGTTTTATGGGCGTCATTCTAG

Upstream 100 bases:

>100_bases
ATCAATAAGAAATAAATCAATTACTTTGATAATTATTTCTGGTTTTTAATGAAATCTGAGGTAATATAATCGCATTGTAC
TAGTTGAGTGATACATTTTA

Downstream 100 bases:

>100_bases
TTAGTTAGAAATACTCAACATTCAAACTGTCTCGTCCTAAAATATAAAAAAAGCCAGCATGTTAATTATGCTGGCTTTTT
ACTTTTGATTGGATTTGTTT

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSSNRESFSSRLGFILAAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLIMILVVAFPMLVVEMAIGRHGQANPVDSMRSL
TSNPLGKKFGAFVGWIGLSVPSAVLMFYSIVGGWLICFLLGAMANVVGLNDVAEWFKGFSIERNLLGTILFYVLTILIVQ
GGIKDGIEKWSTRLMPALFILFGLLFVYIMLQQGAVEGLKHYLIPDFEKVMDKKLILAAMGQGFFSLTIGGCSMLIYGSY
LSKKENLPKMAMNVTLVDTAVAFIAGLVVCLQCLLLCKKASIYAEDGSLLSSDTLVFTVLPMMFDSLGLFGDLFAIVFFA
LLTIAALTSSISMLECSVSLVSERFETKRTPTSWVLGSLIAAFSVVIVFNFGELFGLVAMIATQYLQPIAALLFCVFGGW
VWSRHSKIKELEQGYPEFQQGFFGKIWPLYVKFVCPILVITVLWASF

Sequences:

>Translated_447_residues
MSSNRESFSSRLGFILAAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLIMILVVAFPMLVVEMAIGRHGQANPVDSMRSL
TSNPLGKKFGAFVGWIGLSVPSAVLMFYSIVGGWLICFLLGAMANVVGLNDVAEWFKGFSIERNLLGTILFYVLTILIVQ
GGIKDGIEKWSTRLMPALFILFGLLFVYIMLQQGAVEGLKHYLIPDFEKVMDKKLILAAMGQGFFSLTIGGCSMLIYGSY
LSKKENLPKMAMNVTLVDTAVAFIAGLVVCLQCLLLCKKASIYAEDGSLLSSDTLVFTVLPMMFDSLGLFGDLFAIVFFA
LLTIAALTSSISMLECSVSLVSERFETKRTPTSWVLGSLIAAFSVVIVFNFGELFGLVAMIATQYLQPIAALLFCVFGGW
VWSRHSKIKELEQGYPEFQQGFFGKIWPLYVKFVCPILVITVLWASF
>Mature_446_residues
SSNRESFSSRLGFILAAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLIMILVVAFPMLVVEMAIGRHGQANPVDSMRSLT
SNPLGKKFGAFVGWIGLSVPSAVLMFYSIVGGWLICFLLGAMANVVGLNDVAEWFKGFSIERNLLGTILFYVLTILIVQG
GIKDGIEKWSTRLMPALFILFGLLFVYIMLQQGAVEGLKHYLIPDFEKVMDKKLILAAMGQGFFSLTIGGCSMLIYGSYL
SKKENLPKMAMNVTLVDTAVAFIAGLVVCLQCLLLCKKASIYAEDGSLLSSDTLVFTVLPMMFDSLGLFGDLFAIVFFAL
LTIAALTSSISMLECSVSLVSERFETKRTPTSWVLGSLIAAFSVVIVFNFGELFGLVAMIATQYLQPIAALLFCVFGGWV
WSRHSKIKELEQGYPEFQQGFFGKIWPLYVKFVCPILVITVLWASF

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507043, Length=422, Percent_Identity=24.8815165876777, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI11181770, Length=343, Percent_Identity=24.4897959183673, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI12408638, Length=312, Percent_Identity=26.2820512820513, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI188528618, Length=386, Percent_Identity=24.0932642487047, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4507041, Length=451, Percent_Identity=24.390243902439, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI134304856, Length=408, Percent_Identity=24.0196078431373, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI58219014, Length=306, Percent_Identity=23.8562091503268, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI289191351, Length=411, Percent_Identity=24.0875912408759, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI4557046, Length=411, Percent_Identity=24.0875912408759, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI289191377, Length=411, Percent_Identity=23.8442822384428, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI171184408, Length=389, Percent_Identity=23.3933161953728, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI171184406, Length=389, Percent_Identity=23.3933161953728, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI171184404, Length=389, Percent_Identity=23.3933161953728, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI33354281, Length=302, Percent_Identity=23.841059602649, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI21361581, Length=411, Percent_Identity=23.1143552311436, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI194018524, Length=306, Percent_Identity=23.8562091503268, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI5032097, Length=320, Percent_Identity=26.5625, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI197276623, Length=313, Percent_Identity=23.961661341853, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI54607094, Length=313, Percent_Identity=23.961661341853, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI7657587, Length=470, Percent_Identity=23.8297872340426, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI21361693, Length=114, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI51468073, Length=301, Percent_Identity=21.5946843853821, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI92859670, Length=78, Percent_Identity=42.3076923076923, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI218563756, Length=297, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI6005715, Length=167, Percent_Identity=25.748502994012, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI197276625, Length=65, Percent_Identity=44.6153846153846, Blast_Score=65, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17554804, Length=476, Percent_Identity=25, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71995588, Length=385, Percent_Identity=25.7142857142857, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25146584, Length=403, Percent_Identity=24.317617866005, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI212642127, Length=120, Percent_Identity=32.5, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17535731, Length=120, Percent_Identity=32.5, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17542050, Length=136, Percent_Identity=31.6176470588235, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555248, Length=115, Percent_Identity=33.0434782608696, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19921352, Length=405, Percent_Identity=23.7037037037037, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24584353, Length=405, Percent_Identity=23.7037037037037, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24639514, Length=513, Percent_Identity=23.1968810916179, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI221329674, Length=513, Percent_Identity=23.1968810916179, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI281365034, Length=401, Percent_Identity=23.6907730673317, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24762620, Length=388, Percent_Identity=25.5154639175258, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24639516, Length=529, Percent_Identity=22.8733459357278, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24661428, Length=383, Percent_Identity=23.7597911227154, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24652942, Length=383, Percent_Identity=25.065274151436, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45551088, Length=383, Percent_Identity=25.065274151436, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17136952, Length=390, Percent_Identity=22.8205128205128, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281363702, Length=484, Percent_Identity=23.5537190082645, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24655079, Length=303, Percent_Identity=25.0825082508251, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI19921936, Length=388, Percent_Identity=21.9072164948454, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI281364394, Length=390, Percent_Identity=22.8205128205128, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28574704, Length=390, Percent_Identity=22.8205128205128, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17136950, Length=390, Percent_Identity=22.8205128205128, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28574702, Length=390, Percent_Identity=22.8205128205128, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24639853, Length=401, Percent_Identity=22.1945137157107, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24654186, Length=125, Percent_Identity=33.6, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45550877, Length=64, Percent_Identity=46.875, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45551183, Length=64, Percent_Identity=46.875, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI281364136, Length=124, Percent_Identity=32.258064516129, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48721; Mature: 48590

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSNRESFSSRLGFILAAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLIMILVVAFPMLV
CCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH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CCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]