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The map label for this gene is bglK [H]

Identifier: 59711213

GI number: 59711213

Start: 665634

End: 666569

Strand: Direct

Name: bglK [H]

Synonym: VF_0606

Alternate gene names: 59711213

Gene position: 665634-666569 (Clockwise)

Preceding gene: 59711212

Following gene: 59711214

Centisome position: 22.97

GC content: 31.84

Gene sequence:

>936_bases
ATGGCAACGTACATTTCGTTTGATATTGGTGGTACAGACATAAAGTTTGGCGTGTTAAATGAACAAGGAAAAGTTCTTGA
GCAAGGGAAAGTGAAAACTGAAACTTGCGGAGAAAAAATCATTGCCACTCTTGTGGATATAAAAGAGCAGTGGTCAAAAA
AGTATACGTTCGATGGTGCAGCTTTCTCTCTTCCTGGATTTGTAGATGTAAACACAGGGTATTTAAAAACGGGTGGAGCA
ATTGATGATTTCTACGGTTTTCAATTTAAAGATGAATTAACCAAGAAGTTATCGTTACCTGTTGAATTAGAGAATGATGT
TAACTGTGTAGCGCTTGCTGAAAAATGGCTCGGTAAAGCACAACATGTTGAGAATTTTATCTGTATTACGATAGGCACAG
GTATTGGTGGTGCTATCTATATTAATAATCAAATGGTTCGAGGTCATGGCTTTATGGCTGGAGAGTTTGGTTATATGTTT
ACAAGAAATGTATTTGATATTGAAGATAAAGCAACAGCAAGTATGAGTTTTACTGCATCAGTCAGAGAAGGGTTAAGACG
TCGTTATTCAACATTAAAAAATATTAATAGTATTGATAATATATCAGGAAAAGATATTTTTGAACTCGCATCAACAGGTG
ATGAAGTAGCAATAAAAGTAATTGATGACTTTTATAATAATATTGCTATCGGTTTATATAACCTTACGTTTATTTTAAAT
CCAGAAAAAATAATTATTGGTGGAGCGATAAGTAGTCGAGAAGATTTGATTTCTAATATTGAAAAGAAATTTAATCAGAT
TATTAAAAGCCAAAGTTCAATTAATGAATTTAATGTTAAAGAGTTAGTTTCCATTGAGAAAAGTACATTTAATAATGACA
GTGGATTAATTGGAGCGGTATATCACTTTTTAACAATGAAAAACAAATTTAAATAG

Upstream 100 bases:

>100_bases
GATTGGCTCGTAAGAAAAAAGCATCATTCCACTGGTTTAAAGATGTCATAGCCACTCGTGGTGAAGATATTTAACTGAAA
TAAAGAGAGAAGTTCGCATT

Downstream 100 bases:

>100_bases
GAATAAAGAATATGCTAGTCGGTGAAGAGTTAGAAACTACAGTAATGGAACTTATTATTAATGCAGGTGAATCTAAATCA
TGTGCAATGGAAGCGTTACG

Product: glucokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MATYISFDIGGTDIKFGVLNEQGKVLEQGKVKTETCGEKIIATLVDIKEQWSKKYTFDGAAFSLPGFVDVNTGYLKTGGA
IDDFYGFQFKDELTKKLSLPVELENDVNCVALAEKWLGKAQHVENFICITIGTGIGGAIYINNQMVRGHGFMAGEFGYMF
TRNVFDIEDKATASMSFTASVREGLRRRYSTLKNINSIDNISGKDIFELASTGDEVAIKVIDDFYNNIAIGLYNLTFILN
PEKIIIGGAISSREDLISNIEKKFNQIIKSQSSINEFNVKELVSIEKSTFNNDSGLIGAVYHFLTMKNKFK

Sequences:

>Translated_311_residues
MATYISFDIGGTDIKFGVLNEQGKVLEQGKVKTETCGEKIIATLVDIKEQWSKKYTFDGAAFSLPGFVDVNTGYLKTGGA
IDDFYGFQFKDELTKKLSLPVELENDVNCVALAEKWLGKAQHVENFICITIGTGIGGAIYINNQMVRGHGFMAGEFGYMF
TRNVFDIEDKATASMSFTASVREGLRRRYSTLKNINSIDNISGKDIFELASTGDEVAIKVIDDFYNNIAIGLYNLTFILN
PEKIIIGGAISSREDLISNIEKKFNQIIKSQSSINEFNVKELVSIEKSTFNNDSGLIGAVYHFLTMKNKFK
>Mature_310_residues
ATYISFDIGGTDIKFGVLNEQGKVLEQGKVKTETCGEKIIATLVDIKEQWSKKYTFDGAAFSLPGFVDVNTGYLKTGGAI
DDFYGFQFKDELTKKLSLPVELENDVNCVALAEKWLGKAQHVENFICITIGTGIGGAIYINNQMVRGHGFMAGEFGYMFT
RNVFDIEDKATASMSFTASVREGLRRRYSTLKNINSIDNISGKDIFELASTGDEVAIKVIDDFYNNIAIGLYNLTFILNP
EKIIIGGAISSREDLISNIEKKFNQIIKSQSSINEFNVKELVSIEKSTFNNDSGLIGAVYHFLTMKNKFK

Specific function: Catalyzes the ATP-dependent phosphorylation of a wide variety of beta-D-glucosides, to produce 6-phospho-beta-D- glucosides including cellobiose-6'-P, gentiobiose-6'-P, cellobiitol-6-P, salicin-6-P, and arbutin-6-P. Is not able to phosphorylate alpha-D-gl

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI4885285, Length=269, Percent_Identity=23.4200743494424, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI298566325, Length=269, Percent_Identity=23.4200743494424, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI298566315, Length=269, Percent_Identity=23.4200743494424, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI190014632, Length=267, Percent_Identity=23.5955056179775, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1787363, Length=316, Percent_Identity=22.1518987341772, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081733, Length=312, Percent_Identity=25, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.85 [H]

Molecular weight: Translated: 34537; Mature: 34406

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYISFDIGGTDIKFGVLNEQGKVLEQGKVKTETCGEKIIATLVDIKEQWSKKYTFDGA
CCEEEEEECCCCEEEEEEECCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCC
AFSLPGFVDVNTGYLKTGGAIDDFYGFQFKDELTKKLSLPVELENDVNCVALAEKWLGKA
EECCCCEEECCCCEEECCCCCHHHCCCEEHHHHHHHHCCCEEECCCCCCEEHHHHHCCHH
QHVENFICITIGTGIGGAIYINNQMVRGHGFMAGEFGYMFTRNVFDIEDKATASMSFTAS
HHCCCEEEEEEECCCCEEEEECCEEEECCCCEEECCCCEEECCEECCCCCCCCCEEEHHH
VREGLRRRYSTLKNINSIDNISGKDIFELASTGDEVAIKVIDDFYNNIAIGLYNLTFILN
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHCCEEEEEEEEEEEEC
PEKIIIGGAISSREDLISNIEKKFNQIIKSQSSINEFNVKELVSIEKSTFNNDSGLIGAV
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHH
YHFLTMKNKFK
HHHHHHHCCCC
>Mature Secondary Structure 
ATYISFDIGGTDIKFGVLNEQGKVLEQGKVKTETCGEKIIATLVDIKEQWSKKYTFDGA
CEEEEEECCCCEEEEEEECCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCC
AFSLPGFVDVNTGYLKTGGAIDDFYGFQFKDELTKKLSLPVELENDVNCVALAEKWLGKA
EECCCCEEECCCCEEECCCCCHHHCCCEEHHHHHHHHCCCEEECCCCCCEEHHHHHCCHH
QHVENFICITIGTGIGGAIYINNQMVRGHGFMAGEFGYMFTRNVFDIEDKATASMSFTAS
HHCCCEEEEEEECCCCEEEEECCEEEECCCCEEECCCCEEECCEECCCCCCCCCEEEHHH
VREGLRRRYSTLKNINSIDNISGKDIFELASTGDEVAIKVIDDFYNNIAIGLYNLTFILN
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHCCEEEEEEEEEEEEC
PEKIIIGGAISSREDLISNIEKKFNQIIKSQSSINEFNVKELVSIEKSTFNNDSGLIGAV
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHH
YHFLTMKNKFK
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12110692 [H]