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The map label for this gene is yeiM [C]

Identifier: 59711109

GI number: 59711109

Start: 539290

End: 540546

Strand: Direct

Name: yeiM [C]

Synonym: VF_0502

Alternate gene names: 59711109

Gene position: 539290-540546 (Clockwise)

Preceding gene: 59711108

Following gene: 59711110

Centisome position: 18.61

GC content: 43.6

Gene sequence:

>1257_bases
ATGAGCCTGCTAATGAGTTTGGTTGGGATCGTGGTACTGCTGGGTATAGCTGTACTTCTTTCTGATAACCGTAAAGCAAT
CAATCTACGCACAGTCGGTGGCGCTTTTGCTATCCAATTCTTCTTAGGCGCATTTGTACTTTATGTACCTGTGGGTCGTG
ATGTACTTTATGGTGCATCGGAAGCTGTTGCTAACGTAATTAACTACGGTAACCAAGGTATCGAATTCTTATTCGGTGGT
TTAGTTTCTGGTAAAATGTTCGAAGTATTTGGTGGCGGCGGTTTCGTATTCGCACTACGTGTACTTCCTGTAATCGTATT
CTTTGCTTCTTTAACTGCTGTTCTTTACTACCTAGGTATCATGCAAATCGTGATTAACTTCCTAGGTGGCGCACTGCAGA
AAGCACTTGGCACATCTCGTGCGGAATCACTATCTGCTACAGCTAACATCTTTGTTGGTCAAACAGAAGCGCCGCTAGTT
GTGCGTCCGTTTGTTCCAAAAATGACTCAATCTGAGCTATTTGCAGTAATGTGTGGTGGTCTAGCATCTGTTGCTGGTGG
TGTACTAGCTGGTTATGCATCTATGGGCGTGCCTCTAGAGTACCTAATCGCAGCATCATTCATGGCTGCACCAGGTGGTC
TTCTATTCGCTAAAATTATTAAACCAGAAACAGAGCAACCAATTGAGCAACTAGATGCTCTAAATAACGAAGGTGATGAT
AAACCAGCTAACGTTATTGATGCTGCTGCTGCTGGTGCTGCAACAGGTATGCAACTTGCGTTAAACGTAGGTGCGATGCT
TCTTGCATTCATCGGTTTAATCGCTCTAATCAATGGTATCTTAGGTGGTATCGGTGGTTGGTTCGATATGCCTCATATCA
CTTTAGAACTGATTCTAGGTTACATCTTTGCTCCTTTAGCATTCTTAATCGGTGTTCCATGGGAAGAAGCAACAATTGCT
GGTTCATTCCTTGGTCAAAAACTGGTAGTTAACGAATTCGTTGCATACCTAAACTTTGCACCTTACCTAGCTAATGGCGC
AGAAGTGGTTCTTTCTGAGAAAACAGAAGCAATCATCTCATTCGCACTATGTGGTTTCGCAAACCTTTCTTCTGTAGCGA
TTCTACTTGGTGGTCTAGGTAGCCTTGCACCAGCACGTCGTCATGACATCGCTCGCATGGGTATGAAAGCGGTTGCTGCT
GGTACATTATCAAACCTAATGTCTGCAACAATTGCAGGTCTATTCCTATCTCTATAA

Upstream 100 bases:

>100_bases
ATTATGTGACAACAGCATTACTTTCTTTGTGGTTCAATGAGTATAATCGCCCCCGCTAATTTGAAACACGCCAACAATAA
ATTTAGGGAAAACTTTAACT

Downstream 100 bases:

>100_bases
TCGTATAGAGCAGAACAGATAATCATTATAAAACCCGCATTATGTGCGGGTTTTTTTATGTCTGTTACTCATGAAAAAGT
GTGATGAATAAATGCGCTAA

Product: nucleoside transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSLLMSLVGIVVLLGIAVLLSDNRKAINLRTVGGAFAIQFFLGAFVLYVPVGRDVLYGASEAVANVINYGNQGIEFLFGG
LVSGKMFEVFGGGGFVFALRVLPVIVFFASLTAVLYYLGIMQIVINFLGGALQKALGTSRAESLSATANIFVGQTEAPLV
VRPFVPKMTQSELFAVMCGGLASVAGGVLAGYASMGVPLEYLIAASFMAAPGGLLFAKIIKPETEQPIEQLDALNNEGDD
KPANVIDAAAAGAATGMQLALNVGAMLLAFIGLIALINGILGGIGGWFDMPHITLELILGYIFAPLAFLIGVPWEEATIA
GSFLGQKLVVNEFVAYLNFAPYLANGAEVVLSEKTEAIISFALCGFANLSSVAILLGGLGSLAPARRHDIARMGMKAVAA
GTLSNLMSATIAGLFLSL

Sequences:

>Translated_418_residues
MSLLMSLVGIVVLLGIAVLLSDNRKAINLRTVGGAFAIQFFLGAFVLYVPVGRDVLYGASEAVANVINYGNQGIEFLFGG
LVSGKMFEVFGGGGFVFALRVLPVIVFFASLTAVLYYLGIMQIVINFLGGALQKALGTSRAESLSATANIFVGQTEAPLV
VRPFVPKMTQSELFAVMCGGLASVAGGVLAGYASMGVPLEYLIAASFMAAPGGLLFAKIIKPETEQPIEQLDALNNEGDD
KPANVIDAAAAGAATGMQLALNVGAMLLAFIGLIALINGILGGIGGWFDMPHITLELILGYIFAPLAFLIGVPWEEATIA
GSFLGQKLVVNEFVAYLNFAPYLANGAEVVLSEKTEAIISFALCGFANLSSVAILLGGLGSLAPARRHDIARMGMKAVAA
GTLSNLMSATIAGLFLSL
>Mature_417_residues
SLLMSLVGIVVLLGIAVLLSDNRKAINLRTVGGAFAIQFFLGAFVLYVPVGRDVLYGASEAVANVINYGNQGIEFLFGGL
VSGKMFEVFGGGGFVFALRVLPVIVFFASLTAVLYYLGIMQIVINFLGGALQKALGTSRAESLSATANIFVGQTEAPLVV
RPFVPKMTQSELFAVMCGGLASVAGGVLAGYASMGVPLEYLIAASFMAAPGGLLFAKIIKPETEQPIEQLDALNNEGDDK
PANVIDAAAAGAATGMQLALNVGAMLLAFIGLIALINGILGGIGGWFDMPHITLELILGYIFAPLAFLIGVPWEEATIAG
SFLGQKLVVNEFVAYLNFAPYLANGAEVVLSEKTEAIISFALCGFANLSSVAILLGGLGSLAPARRHDIARMGMKAVAAG
TLSNLMSATIAGLFLSL

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI11545853, Length=368, Percent_Identity=39.945652173913, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI42542381, Length=424, Percent_Identity=37.9716981132075, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI227116277, Length=421, Percent_Identity=36.104513064133, Blast_Score=266, Evalue=4e-71,
Organism=Escherichia coli, GI1788485, Length=418, Percent_Identity=50.4784688995215, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1788488, Length=418, Percent_Identity=50.4784688995215, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1788737, Length=401, Percent_Identity=30.4239401496259, Blast_Score=176, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17560276, Length=399, Percent_Identity=30.0751879699248, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI71991794, Length=401, Percent_Identity=29.925187032419, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI25146537, Length=233, Percent_Identity=29.1845493562232, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45552517, Length=414, Percent_Identity=36.9565217391304, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI19921868, Length=414, Percent_Identity=36.9565217391304, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI45552519, Length=414, Percent_Identity=36.9565217391304, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI281360430, Length=406, Percent_Identity=36.4532019704434, Blast_Score=247, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 43370; Mature: 43239

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLMSLVGIVVLLGIAVLLSDNRKAINLRTVGGAFAIQFFLGAFVLYVPVGRDVLYGAS
CHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHCCH
EAVANVINYGNQGIEFLFGGLVSGKMFEVFGGGGFVFALRVLPVIVFFASLTAVLYYLGI
HHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQIVINFLGGALQKALGTSRAESLSATANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCCCEEEECCCCCCHHHHHHHHHHHH
LASVAGGVLAGYASMGVPLEYLIAASFMAAPGGLLFAKIIKPETEQPIEQLDALNNEGDD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCC
KPANVIDAAAAGAATGMQLALNVGAMLLAFIGLIALINGILGGIGGWFDMPHITLELILG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHH
YIFAPLAFLIGVPWEEATIAGSFLGQKLVVNEFVAYLNFAPYLANGAEVVLSEKTEAIIS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
FALCGFANLSSVAILLGGLGSLAPARRHDIARMGMKAVAAGTLSNLMSATIAGLFLSL
HHHHHHCHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLLMSLVGIVVLLGIAVLLSDNRKAINLRTVGGAFAIQFFLGAFVLYVPVGRDVLYGAS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHCCH
EAVANVINYGNQGIEFLFGGLVSGKMFEVFGGGGFVFALRVLPVIVFFASLTAVLYYLGI
HHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQIVINFLGGALQKALGTSRAESLSATANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCCCEEEECCCCCCHHHHHHHHHHHH
LASVAGGVLAGYASMGVPLEYLIAASFMAAPGGLLFAKIIKPETEQPIEQLDALNNEGDD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCC
KPANVIDAAAAGAATGMQLALNVGAMLLAFIGLIALINGILGGIGGWFDMPHITLELILG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHH
YIFAPLAFLIGVPWEEATIAGSFLGQKLVVNEFVAYLNFAPYLANGAEVVLSEKTEAIIS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
FALCGFANLSSVAILLGGLGSLAPARRHDIARMGMKAVAAGTLSNLMSATIAGLFLSL
HHHHHHCHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]