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The map label for this gene is yjjV [H]

Identifier: 59711108

GI number: 59711108

Start: 538315

End: 539091

Strand: Direct

Name: yjjV [H]

Synonym: VF_0501

Alternate gene names: 59711108

Gene position: 538315-539091 (Clockwise)

Preceding gene: 172087667

Following gene: 59711109

Centisome position: 18.58

GC content: 36.16

Gene sequence:

>777_bases
ATGGTCTTTACGTTCATTGATTCACATTGTCATTTTGATTTTGACCCTTTTAAGAATAATGAAGTGTCCTACTTACAAAT
GGCAAAAGATAAAGGCGTTACAACGCTTGTTGTACCCAGTGTAAATCAATCAAACTGGAATCATGTGAGTAGATTGGCAC
ATCAATTTGATGAGATTTACTACGCATTAGGCATTCATCCACTATTTATTACTCCAAGCTATGAAAGGGAGTTAGAAAAT
CTAGGTGAGTTACTTGATGGAAAAAATAAAAAATGTGTAGCGATTGGTGAATGTGGATTGGATTTTTGGTATCCAGAAAG
TGATATAGAAACACAGATCTCTGTTTTTCGTCAGCATTGTTTGTTGGCTAAACAGCATCAACTTCCTCTGATTGTTCACA
GTCGTAAAAGTCACGATATGGTATTAAAGCTGTTGAGAGAAATTCAGCCAGAGAGAGGTGGAGTAATTCACGGGTTTAGT
GGTAGCTTGCAGCAGGCCAATCAGTTCATTGACTTAGGGTTTTATATTGGTGTTGGTGGCGTGATCAGTTACGAAAGGGC
AAAGAAGACTAAAATGGTTATTTCACAGCTACCTTTAGATAAAATTATATTAGAAACTGACGCACCAGACATGCCATTAT
TTGGCTTTCAAGGTGAAAAAAATAGCCCTGATAAAGTACGAAATGTATTCGAATATCTCTCTTTGATTAGAAAAGAATCA
ATGCAAACGATTTCGGAAACTGTTTATAAAAATACCACCTCTTTGTTTGGGATTTGA

Upstream 100 bases:

>100_bases
TTAAATTATGGATACGAAAGTATGATGCATGGTGTGAGTCATTAGGCTTAACACCAGAAAACAAGCGCAGTTGTGTTCCT
TATAGAAAAGAAGAAGAGTA

Downstream 100 bases:

>100_bases
GTTATCAGTCATTTCTTTAGTTGTAATTGATGATTATTTAGAAACACCTTAGTGATAATGATCACAATTATGGATGAATA
AAGCATGTATCAGCCACGAT

Product: Dnase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MVFTFIDSHCHFDFDPFKNNEVSYLQMAKDKGVTTLVVPSVNQSNWNHVSRLAHQFDEIYYALGIHPLFITPSYERELEN
LGELLDGKNKKCVAIGECGLDFWYPESDIETQISVFRQHCLLAKQHQLPLIVHSRKSHDMVLKLLREIQPERGGVIHGFS
GSLQQANQFIDLGFYIGVGGVISYERAKKTKMVISQLPLDKIILETDAPDMPLFGFQGEKNSPDKVRNVFEYLSLIRKES
MQTISETVYKNTTSLFGI

Sequences:

>Translated_258_residues
MVFTFIDSHCHFDFDPFKNNEVSYLQMAKDKGVTTLVVPSVNQSNWNHVSRLAHQFDEIYYALGIHPLFITPSYERELEN
LGELLDGKNKKCVAIGECGLDFWYPESDIETQISVFRQHCLLAKQHQLPLIVHSRKSHDMVLKLLREIQPERGGVIHGFS
GSLQQANQFIDLGFYIGVGGVISYERAKKTKMVISQLPLDKIILETDAPDMPLFGFQGEKNSPDKVRNVFEYLSLIRKES
MQTISETVYKNTTSLFGI
>Mature_258_residues
MVFTFIDSHCHFDFDPFKNNEVSYLQMAKDKGVTTLVVPSVNQSNWNHVSRLAHQFDEIYYALGIHPLFITPSYERELEN
LGELLDGKNKKCVAIGECGLDFWYPESDIETQISVFRQHCLLAKQHQLPLIVHSRKSHDMVLKLLREIQPERGGVIHGFS
GSLQQANQFIDLGFYIGVGGVISYERAKKTKMVISQLPLDKIILETDAPDMPLFGFQGEKNSPDKVRNVFEYLSLIRKES
MQTISETVYKNTTSLFGI

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=259, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI225903439, Length=239, Percent_Identity=29.7071129707113, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI110349730, Length=265, Percent_Identity=26.7924528301887, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI110349734, Length=265, Percent_Identity=27.5471698113208, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI226061853, Length=271, Percent_Identity=27.3062730627306, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI225903424, Length=221, Percent_Identity=27.1493212669683, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226061595, Length=244, Percent_Identity=27.4590163934426, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI226061614, Length=254, Percent_Identity=25.5905511811024, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=44.1860465116279, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1787342, Length=259, Percent_Identity=29.3436293436293, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI48994985, Length=248, Percent_Identity=26.6129032258064, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17559024, Length=215, Percent_Identity=28.8372093023256, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=25.1908396946565, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=312, Percent_Identity=25, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648690, Length=269, Percent_Identity=26.3940520446097, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221330018, Length=266, Percent_Identity=26.3157894736842, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24586117, Length=266, Percent_Identity=26.3157894736842, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 29475; Mature: 29475

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFTFIDSHCHFDFDPFKNNEVSYLQMAKDKGVTTLVVPSVNQSNWNHVSRLAHQFDEIY
CEEEEEECCCCCCCCCCCCCCHHHEEEHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
YALGIHPLFITPSYERELENLGELLDGKNKKCVAIGECGLDFWYPESDIETQISVFRQHC
HHHCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHH
LLAKQHQLPLIVHSRKSHDMVLKLLREIQPERGGVIHGFSGSLQQANQFIDLGFYIGVGG
HHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCC
VISYERAKKTKMVISQLPLDKIILETDAPDMPLFGFQGEKNSPDKVRNVFEYLSLIRKES
EEEHHHHHHHHHHHHHCCHHHEEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHH
MQTISETVYKNTTSLFGI
HHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MVFTFIDSHCHFDFDPFKNNEVSYLQMAKDKGVTTLVVPSVNQSNWNHVSRLAHQFDEIY
CEEEEEECCCCCCCCCCCCCCHHHEEEHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
YALGIHPLFITPSYERELENLGELLDGKNKKCVAIGECGLDFWYPESDIETQISVFRQHC
HHHCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHH
LLAKQHQLPLIVHSRKSHDMVLKLLREIQPERGGVIHGFSGSLQQANQFIDLGFYIGVGG
HHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCC
VISYERAKKTKMVISQLPLDKIILETDAPDMPLFGFQGEKNSPDKVRNVFEYLSLIRKES
EEEHHHHHHHHHHHHHCCHHHEEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHH
MQTISETVYKNTTSLFGI
HHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]