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The map label for this gene is nlpI [H]

Identifier: 59711098

GI number: 59711098

Start: 528397

End: 529380

Strand: Direct

Name: nlpI [H]

Synonym: VF_0491

Alternate gene names: 59711098

Gene position: 528397-529380 (Clockwise)

Preceding gene: 59711097

Following gene: 59711102

Centisome position: 18.24

GC content: 37.6

Gene sequence:

>984_bases
GTGAATTGGATTCGAGTAGCCTTAGTTGGCGCAGTATTAGTGTTGTCTGGGTGTGCATCTAAAGGGGATACTTCAGGATG
GGGATACCCACCAATGGCGGTTCCTTTACAACCAAGTATCCAACAAGAGATCCAATTATCTCGTTTGGACCAATTGCTAC
AACGCCCCGATGTGGATGATGTAACTCGTGCAAAAATGTACTATGAAAGAGGGTTAATTAAAGACAGTTTAGGTTTACGT
GACTTGGCTCGTGTCGACTTTACTCAATCTTTAACTTTAAAACCTGATCAGAGTGATGTGTTTAATATTCTTGGTGTTTA
CTACACGCAAAATACGGATTTTGATGGAGCGTATGAAGCGTTAGATTCAGCTTTAGAATTAGACCCAAATAATCAATTTG
CTGAACGTAATTTAGCTATCGCTTTGTATTATGGTGAACGTTACGATCAAGCATATGAAATAGCTCAGAAGCATTACAAT
GATGCTCCTCGTGACCCATACCGTGCAATTTGGTTGTATTGGATTGGATTAGAAGTGGATGCGAAAGTGGCAACAGAGAC
CTTCCAGAAACAATATCAACAAAGAACAGATGAAGATTTTGGATGGGATCTTGCAGGGTTAATTTTAAAAGAAACTTCTG
AAGATGAGTTTTTGAAAAAAATCTTAACTACAACTCGTAATAATGTGGCATTGGCAGAAAAACTAACAGAAGGTTATTTT
TATTTAGCTAAACGTTATCAATACGAAGGTGATTATCCAAACGCAATTGCTTTGTATAAGCTAAGTATGTCGAACAACGT
TTATGAGTATGTAGAACATCGATATTCATTTGTGGAACTAGGTAATATCTACAAAGCTTTACGTGATTTGCAAGAGCAAA
AAATAAAAGAGCAGCAAGCACAAGAAGCGAAAGAAGCACCGGTTGCACCACAAGAAAAAAGCACTGAAAAAGAGATGCTA
AAAGAAGAAGCAACAGCAAAATAA

Upstream 100 bases:

>100_bases
TGATTTAAAGCATGTTATAAAGGGAGCAGAAATGCTCCCTTTTCTTTTAATATAGAGTCACTTTTATTAAAAGAATTAGG
TTTATCATAGGAGAAAATGA

Downstream 100 bases:

>100_bases
TTAGCTACATTAGTATAATAAAAAAGCCTTATTCATATGGATAAGGCTTTTTTGTATTCAAAAGAAAATTCAAAATTACA
TTTGAATGTCTAATCCAGCA

Product: lipoprotein NlpI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNWIRVALVGAVLVLSGCASKGDTSGWGYPPMAVPLQPSIQQEIQLSRLDQLLQRPDVDDVTRAKMYYERGLIKDSLGLR
DLARVDFTQSLTLKPDQSDVFNILGVYYTQNTDFDGAYEALDSALELDPNNQFAERNLAIALYYGERYDQAYEIAQKHYN
DAPRDPYRAIWLYWIGLEVDAKVATETFQKQYQQRTDEDFGWDLAGLILKETSEDEFLKKILTTTRNNVALAEKLTEGYF
YLAKRYQYEGDYPNAIALYKLSMSNNVYEYVEHRYSFVELGNIYKALRDLQEQKIKEQQAQEAKEAPVAPQEKSTEKEML
KEEATAK

Sequences:

>Translated_327_residues
MNWIRVALVGAVLVLSGCASKGDTSGWGYPPMAVPLQPSIQQEIQLSRLDQLLQRPDVDDVTRAKMYYERGLIKDSLGLR
DLARVDFTQSLTLKPDQSDVFNILGVYYTQNTDFDGAYEALDSALELDPNNQFAERNLAIALYYGERYDQAYEIAQKHYN
DAPRDPYRAIWLYWIGLEVDAKVATETFQKQYQQRTDEDFGWDLAGLILKETSEDEFLKKILTTTRNNVALAEKLTEGYF
YLAKRYQYEGDYPNAIALYKLSMSNNVYEYVEHRYSFVELGNIYKALRDLQEQKIKEQQAQEAKEAPVAPQEKSTEKEML
KEEATAK
>Mature_327_residues
MNWIRVALVGAVLVLSGCASKGDTSGWGYPPMAVPLQPSIQQEIQLSRLDQLLQRPDVDDVTRAKMYYERGLIKDSLGLR
DLARVDFTQSLTLKPDQSDVFNILGVYYTQNTDFDGAYEALDSALELDPNNQFAERNLAIALYYGERYDQAYEIAQKHYN
DAPRDPYRAIWLYWIGLEVDAKVATETFQKQYQQRTDEDFGWDLAGLILKETSEDEFLKKILTTTRNNVALAEKLTEGYF
YLAKRYQYEGDYPNAIALYKLSMSNNVYEYVEHRYSFVELGNIYKALRDLQEQKIKEQQAQEAKEAPVAPQEKSTEKEML
KEEATAK

Specific function: May be involved in cell division. Overexpression of nlpI results in the loss of the rod morphology and the formation of single prolate ellipsoids and pairs of prolate ellipsoids joined by partial constrictions [H]

COG id: COG4785

COG function: function code R; Lipoprotein NlpI, contains TPR repeats

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789554, Length=290, Percent_Identity=42.7586206896552, Blast_Score=241, Evalue=5e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 37684; Mature: 37684

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWIRVALVGAVLVLSGCASKGDTSGWGYPPMAVPLQPSIQQEIQLSRLDQLLQRPDVDD
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCH
VTRAKMYYERGLIKDSLGLRDLARVDFTQSLTLKPDQSDVFNILGVYYTQNTDFDGAYEA
HHHHHHHHHHCCHHHCCCHHHHHHHCCCCCEECCCCHHHHHHHHHHEEECCCCCCHHHHH
LDSALELDPNNQFAERNLAIALYYGERYDQAYEIAQKHYNDAPRDPYRAIWLYWIGLEVD
HHHHHCCCCCCCHHHCCEEEEEEECCHHHHHHHHHHHHCCCCCCCHHHEEEEEEEEEEEC
AKVATETFQKQYQQRTDEDFGWDLAGLILKETSEDEFLKKILTTTRNNVALAEKLTEGYF
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
YLAKRYQYEGDYPNAIALYKLSMSNNVYEYVEHRYSFVELGNIYKALRDLQEQKIKEQQA
HHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEAKEAPVAPQEKSTEKEMLKEEATAK
HHHHHCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNWIRVALVGAVLVLSGCASKGDTSGWGYPPMAVPLQPSIQQEIQLSRLDQLLQRPDVDD
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCH
VTRAKMYYERGLIKDSLGLRDLARVDFTQSLTLKPDQSDVFNILGVYYTQNTDFDGAYEA
HHHHHHHHHHCCHHHCCCHHHHHHHCCCCCEECCCCHHHHHHHHHHEEECCCCCCHHHHH
LDSALELDPNNQFAERNLAIALYYGERYDQAYEIAQKHYNDAPRDPYRAIWLYWIGLEVD
HHHHHCCCCCCCHHHCCEEEEEEECCHHHHHHHHHHHHCCCCCCCHHHEEEEEEEEEEEC
AKVATETFQKQYQQRTDEDFGWDLAGLILKETSEDEFLKKILTTTRNNVALAEKLTEGYF
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
YLAKRYQYEGDYPNAIALYKLSMSNNVYEYVEHRYSFVELGNIYKALRDLQEQKIKEQQA
HHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEAKEAPVAPQEKSTEKEMLKEEATAK
HHHHHCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]