BacMap

Definition	Vibrio fischeri ES114 chromosome I, complete genome.
Accession	NC_006840
Length	2,897,536

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The map label for this gene is hflB [H]

Identifier: 59711086

GI number: 59711086

Start: 514087

End: 516060

Strand: Direct

Name: hflB [H]

Synonym: VF_0479

Alternate gene names: 59711086

Gene position: 514087-516060 (Clockwise)

Preceding gene: 59711085

Following gene: 59711087

Centisome position: 17.74

GC content: 41.89

Gene sequence:

>1974_bases
ATGGCAAAAAATCTAATATTATGGCTGGTTATCGCTGTTGTTTTAATGTCGGTATTCCAGAGTTTTGGACCAGGTGATAG
CTCTGGTCGTTCAATTGACTATACGACTTTTGTTAAAGAAGTAGGTAATAGTCAAGTACAAGAAGCAACCTTTAATAATC
GTGAGATTAAGGTAATGAAACGTGACGGCACTCGTTACGTCACATATATGCCAGTATTCCAAGATCCTAAGTTGCTTGAT
GACCTAATTAACCAAAATGTAATCGTTAAAGGTACACCACCAGAAGAGCAGAGCTTACTTGAGTCTATCTTCATCTCGTG
GTTCCCAATGATTCTTCTTATTGGTGTTTGGATCTTCTTCATGCGTCAGATGCAAGGTGGCGGTGGCAAAGGAGCTATGT
CCTTTGGCAAGAGTAAAGCCAAGATGATGACTGAAGAGCAAATCAAAACAACATTTGATGATGTTGCTGGCTGTGATGAA
GCAAAAGAAGATGTAAAAGAGTTAGTTGATTACTTGCGCGAACCAAGCCGTTTCCAAAAACTGGGTGGTAAAATTCCAAC
AGGTGTTCTACTAGTTGGTCCTCCTGGTACAGGTAAAACGCTGATTGCAAAAGCGATTGCTGGTGAAGCAAAGGTACCTT
TCTTCTCAATTTCTGGTTCTGATTTTGTTGAGATGTTTGTGGGTGTTGGTGCATCACGTGTTCGTGATATGTTTGAACAA
GCGAAAAAATCATCACCTTGTATTATCTTCATTGATGAAATCGATGCTGTAGGTCGCCAACGTGGTGCGGGTGTTGGTGG
TGGTAATGATGAGCGTGAGCAAACATTGAACCAAATGCTAGTTGAAATGGATGGCTTTGAAGGTAACGAAGGCATCATTG
TTATTGCTGCGACTAACCGTCCAGATGTACTTGATGCAGCATTACTACGTCCAGGTCGTTTCGACCGTCAAGTTGTTGTT
GGTCTACCTGATATCCGTGGTCGTGAGCAGATCCTTCAAGTTCATATGCGTAAAGTACCATTAGGTGCTGGCGTAGAACC
ATCGTTGATTGCTCGTGGTACTCCTGGCTTCTCTGGTGCAGATCTAGCTAACTTAGTAAACGAAGCTGCTTTGTTTGCGG
CGCGCGGCAATAAGCGTGTTGTTTCAATGGTTGAGTTTGAATTAGCGAAAGATAAAATCATGATGGGCGCAGAGCGTAAA
TCAATGGTTATGTCTGAAGAAACTAAAGAATCAACAGCATATCATGAAGCAGGTCATGCGATTGTTGGTCGTTTAGTTCC
TGAACATGATCCAGTATACAAAGTATCTATCATTCCACGTGGTCGAGCGTTGGGTGTAACTATGTATCTACCAGAACAAG
ATCGTATCAGCATGAACCGTCAACATTTAGAATCGATGATTTCGAGTCTATATGGTGGTCGTTTAGCTGAGGAATTGATT
TACGGTGTTGATAAGGTATCAACTGGTGCATCGAACGATATTGAACGCGCAACAGATATTGCTCGTAAAATGGTAACGCA
ATGGGGCTTCTCTGATGCTCTAGGCCCTCTACTTTATGCAGAAGATCAAGGCGACCCGTTCTCTGGTCACGGTGGTTCTC
ATCAACCTAAGCATGTTTCTCCAGAAACACTGCAATTAATTGATGCTGAGATCCGTACTATCATTGATCGTAACTATGCT
CGTGCAAGACAGATCCTTGAAGATAATATGGATATCATGCATGCGATGAAAGATGCGTTGATGAAGTTTGAAACCATTGA
TGCAGGTCAGATTGATGATCTCATGGATCGTAAAGCTGATATTCGTGAGCCACAAGGTTGGGGTGATAATAACCCACAGC
CTCAAGCGAAGACTGAAGCACCAGTAGAAAAAGAAGAAACAGAATCAAAAGCAGAAGAGAAGGTTGAAGAAACAAAAGAA
CAACCAACTTCAACTGATGAAACAAAAAACGATTCTGAATCATCTGAAAAGTAA

Upstream 100 bases:

>100_bases
GGTTACAAAGGATAAGTTTTACGTAGTAGATACAGAATATAAACTGTAGTACTCTGTCTTTCATCTATTTAGTTAACGCG
GGGTTAACACCTTGAGTGAC

Downstream 100 bases:

>100_bases
GATGAAATAAGATAAATGAAACCCCGAGTTATGCTCGGGGTTTTTGTATTTATTAAAGGTGTAGAGTAATGAAACTAATA
AGTAAAAATAAATCCCTTTT

Product: ATP-dependent zinc-metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 656

Protein sequence:

>657_residues
MAKNLILWLVIAVVLMSVFQSFGPGDSSGRSIDYTTFVKEVGNSQVQEATFNNREIKVMKRDGTRYVTYMPVFQDPKLLD
DLINQNVIVKGTPPEEQSLLESIFISWFPMILLIGVWIFFMRQMQGGGGKGAMSFGKSKAKMMTEEQIKTTFDDVAGCDE
AKEDVKELVDYLREPSRFQKLGGKIPTGVLLVGPPGTGKTLIAKAIAGEAKVPFFSISGSDFVEMFVGVGASRVRDMFEQ
AKKSSPCIIFIDEIDAVGRQRGAGVGGGNDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDAALLRPGRFDRQVVV
GLPDIRGREQILQVHMRKVPLGAGVEPSLIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFELAKDKIMMGAERK
SMVMSEETKESTAYHEAGHAIVGRLVPEHDPVYKVSIIPRGRALGVTMYLPEQDRISMNRQHLESMISSLYGGRLAEELI
YGVDKVSTGASNDIERATDIARKMVTQWGFSDALGPLLYAEDQGDPFSGHGGSHQPKHVSPETLQLIDAEIRTIIDRNYA
RARQILEDNMDIMHAMKDALMKFETIDAGQIDDLMDRKADIREPQGWGDNNPQPQAKTEAPVEKEETESKAEEKVEETKE
QPTSTDETKNDSESSEK

Sequences:

>Translated_657_residues
MAKNLILWLVIAVVLMSVFQSFGPGDSSGRSIDYTTFVKEVGNSQVQEATFNNREIKVMKRDGTRYVTYMPVFQDPKLLD
DLINQNVIVKGTPPEEQSLLESIFISWFPMILLIGVWIFFMRQMQGGGGKGAMSFGKSKAKMMTEEQIKTTFDDVAGCDE
AKEDVKELVDYLREPSRFQKLGGKIPTGVLLVGPPGTGKTLIAKAIAGEAKVPFFSISGSDFVEMFVGVGASRVRDMFEQ
AKKSSPCIIFIDEIDAVGRQRGAGVGGGNDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDAALLRPGRFDRQVVV
GLPDIRGREQILQVHMRKVPLGAGVEPSLIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFELAKDKIMMGAERK
SMVMSEETKESTAYHEAGHAIVGRLVPEHDPVYKVSIIPRGRALGVTMYLPEQDRISMNRQHLESMISSLYGGRLAEELI
YGVDKVSTGASNDIERATDIARKMVTQWGFSDALGPLLYAEDQGDPFSGHGGSHQPKHVSPETLQLIDAEIRTIIDRNYA
RARQILEDNMDIMHAMKDALMKFETIDAGQIDDLMDRKADIREPQGWGDNNPQPQAKTEAPVEKEETESKAEEKVEETKE
QPTSTDETKNDSESSEK
>Mature_656_residues
AKNLILWLVIAVVLMSVFQSFGPGDSSGRSIDYTTFVKEVGNSQVQEATFNNREIKVMKRDGTRYVTYMPVFQDPKLLDD
LINQNVIVKGTPPEEQSLLESIFISWFPMILLIGVWIFFMRQMQGGGGKGAMSFGKSKAKMMTEEQIKTTFDDVAGCDEA
KEDVKELVDYLREPSRFQKLGGKIPTGVLLVGPPGTGKTLIAKAIAGEAKVPFFSISGSDFVEMFVGVGASRVRDMFEQA
KKSSPCIIFIDEIDAVGRQRGAGVGGGNDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDAALLRPGRFDRQVVVG
LPDIRGREQILQVHMRKVPLGAGVEPSLIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFELAKDKIMMGAERKS
MVMSEETKESTAYHEAGHAIVGRLVPEHDPVYKVSIIPRGRALGVTMYLPEQDRISMNRQHLESMISSLYGGRLAEELIY
GVDKVSTGASNDIERATDIARKMVTQWGFSDALGPLLYAEDQGDPFSGHGGSHQPKHVSPETLQLIDAEIRTIIDRNYAR
ARQILEDNMDIMHAMKDALMKFETIDAGQIDDLMDRKADIREPQGWGDNNPQPQAKTEAPVEKEETESKAEEKVEETKEQ
PTSTDETKNDSESSEK

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI7657689, Length=453, Percent_Identity=48.3443708609272, Blast_Score=440, Evalue=1e-123,
Organism=Homo sapiens, GI21327685, Length=453, Percent_Identity=48.3443708609272, Blast_Score=439, Evalue=1e-123,
Organism=Homo sapiens, GI300192933, Length=505, Percent_Identity=44.7524752475248, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI4507173, Length=516, Percent_Identity=41.0852713178295, Blast_Score=378, Evalue=1e-104,
Organism=Homo sapiens, GI4506209, Length=254, Percent_Identity=41.3385826771654, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI24497435, Length=262, Percent_Identity=41.6030534351145, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI6005942, Length=226, Percent_Identity=40.7079646017699, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI21361144, Length=235, Percent_Identity=41.2765957446808, Blast_Score=189, Evalue=8e-48,
Organism=Homo sapiens, GI195539395, Length=253, Percent_Identity=37.9446640316205, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI24430151, Length=254, Percent_Identity=37.007874015748, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI45643123, Length=280, Percent_Identity=38.5714285714286, Blast_Score=186, Evalue=7e-47,
Organism=Homo sapiens, GI45643125, Length=280, Percent_Identity=38.5714285714286, Blast_Score=186, Evalue=9e-47,
Organism=Homo sapiens, GI89064750, Length=265, Percent_Identity=37.7358490566038, Blast_Score=179, Evalue=8e-45,
Organism=Homo sapiens, GI5729991, Length=265, Percent_Identity=37.7358490566038, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI24430155, Length=265, Percent_Identity=37.7358490566038, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI40806173, Length=137, Percent_Identity=58.3941605839416, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI157671927, Length=224, Percent_Identity=39.2857142857143, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI4505725, Length=229, Percent_Identity=39.3013100436681, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI229577436, Length=246, Percent_Identity=39.0243902439024, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI24497618, Length=268, Percent_Identity=36.9402985074627, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI153792536, Length=231, Percent_Identity=39.3939393939394, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI5901990, Length=233, Percent_Identity=39.4849785407725, Blast_Score=154, Evalue=4e-37,
Organism=Homo sapiens, GI226371754, Length=234, Percent_Identity=38.034188034188, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI194018488, Length=259, Percent_Identity=37.8378378378378, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI14149767, Length=257, Percent_Identity=36.1867704280156, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI62177112, Length=257, Percent_Identity=36.1867704280156, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI156564401, Length=328, Percent_Identity=31.7073170731707, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI7019569, Length=248, Percent_Identity=35.8870967741936, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI31742536, Length=224, Percent_Identity=38.8392857142857, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI112789543, Length=224, Percent_Identity=38.8392857142857, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI11875211, Length=227, Percent_Identity=40.9691629955947, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI40806170, Length=227, Percent_Identity=40.9691629955947, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI310125282, Length=279, Percent_Identity=33.6917562724014, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI310125280, Length=233, Percent_Identity=36.9098712446352, Blast_Score=134, Evalue=4e-31,
Organism=Homo sapiens, GI17865802, Length=254, Percent_Identity=36.2204724409449, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI31377644, Length=246, Percent_Identity=34.5528455284553, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI64084766, Length=273, Percent_Identity=30.03663003663, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI116292174, Length=280, Percent_Identity=29.6428571428571, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI75677353, Length=194, Percent_Identity=32.9896907216495, Blast_Score=73, Evalue=9e-13,
Organism=Escherichia coli, GI1789568, Length=625, Percent_Identity=78.24, Blast_Score=1006, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71994521, Length=443, Percent_Identity=49.4356659142212, Blast_Score=412, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17554264, Length=472, Percent_Identity=45.7627118644068, Blast_Score=410, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI115534323, Length=460, Percent_Identity=42.8260869565217, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI25144278, Length=262, Percent_Identity=43.1297709923664, Blast_Score=222, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI25144281, Length=262, Percent_Identity=43.1297709923664, Blast_Score=221, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI17554786, Length=262, Percent_Identity=42.7480916030534, Blast_Score=221, Evalue=8e-58,
Organism=Caenorhabditis elegans, GI17563248, Length=261, Percent_Identity=41.3793103448276, Blast_Score=214, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI17532375, Length=247, Percent_Identity=40.4858299595142, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17531535, Length=245, Percent_Identity=41.2244897959184, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71987364, Length=254, Percent_Identity=38.9763779527559, Blast_Score=192, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI71987372, Length=254, Percent_Identity=38.9763779527559, Blast_Score=192, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17508701, Length=235, Percent_Identity=42.1276595744681, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17563250, Length=254, Percent_Identity=37.7952755905512, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17505546, Length=252, Percent_Identity=38.8888888888889, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17508053, Length=243, Percent_Identity=40.3292181069959, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17537217, Length=230, Percent_Identity=40, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17554784, Length=251, Percent_Identity=38.2470119521912, Blast_Score=165, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI133931034, Length=248, Percent_Identity=38.7096774193548, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI193206114, Length=248, Percent_Identity=38.7096774193548, Blast_Score=159, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI193206116, Length=248, Percent_Identity=38.7096774193548, Blast_Score=159, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI25153574, Length=248, Percent_Identity=35.0806451612903, Blast_Score=156, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=45.4545454545455, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=45.4545454545455, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI193209502, Length=225, Percent_Identity=36.4444444444444, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI25146157, Length=230, Percent_Identity=40, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17562804, Length=228, Percent_Identity=38.1578947368421, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI133901662, Length=257, Percent_Identity=36.5758754863813, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI133901658, Length=257, Percent_Identity=36.5758754863813, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI86561515, Length=256, Percent_Identity=35.9375, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32563584, Length=241, Percent_Identity=37.344398340249, Blast_Score=128, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17508421, Length=241, Percent_Identity=37.344398340249, Blast_Score=128, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17541224, Length=281, Percent_Identity=34.5195729537367, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17541226, Length=281, Percent_Identity=34.5195729537367, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17560432, Length=224, Percent_Identity=37.5, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71990294, Length=197, Percent_Identity=29.9492385786802, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325281, Length=444, Percent_Identity=48.4234234234234, Blast_Score=452, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6320854, Length=546, Percent_Identity=43.956043956044, Blast_Score=438, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6323736, Length=499, Percent_Identity=46.2925851703407, Blast_Score=434, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6322704, Length=261, Percent_Identity=42.5287356321839, Blast_Score=219, Evalue=8e-58,
Organism=Saccharomyces cerevisiae, GI6320077, Length=247, Percent_Identity=42.5101214574899, Blast_Score=216, Evalue=9e-57,
Organism=Saccharomyces cerevisiae, GI6321390, Length=254, Percent_Identity=40.9448818897638, Blast_Score=211, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6324833, Length=238, Percent_Identity=42.0168067226891, Blast_Score=191, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6324691, Length=246, Percent_Identity=39.8373983739837, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6320197, Length=245, Percent_Identity=36.734693877551, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6324000, Length=251, Percent_Identity=40.2390438247012, Blast_Score=176, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6320602, Length=251, Percent_Identity=39.8406374501992, Blast_Score=173, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6323429, Length=266, Percent_Identity=38.7218045112782, Blast_Score=170, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6321709, Length=282, Percent_Identity=38.2978723404255, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6322651, Length=245, Percent_Identity=37.5510204081633, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322994, Length=212, Percent_Identity=39.1509433962264, Blast_Score=164, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6325431, Length=232, Percent_Identity=38.3620689655172, Blast_Score=143, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6321465, Length=240, Percent_Identity=38.75, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319554, Length=216, Percent_Identity=39.8148148148148, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6325183, Length=253, Percent_Identity=35.1778656126482, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320887, Length=258, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6320583, Length=257, Percent_Identity=25.6809338521401, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24658770, Length=451, Percent_Identity=49.2239467849224, Blast_Score=447, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24665814, Length=500, Percent_Identity=44.8, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI28574878, Length=500, Percent_Identity=44.8, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24639391, Length=450, Percent_Identity=44.8888888888889, Blast_Score=393, Evalue=1e-109,
Organism=Drosophila melanogaster, GI161076486, Length=285, Percent_Identity=37.8947368421053, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI17137560, Length=285, Percent_Identity=37.8947368421053, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI161076488, Length=285, Percent_Identity=37.8947368421053, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI17137738, Length=254, Percent_Identity=41.7322834645669, Blast_Score=212, Evalue=7e-55,
Organism=Drosophila melanogaster, GI24651451, Length=262, Percent_Identity=41.6030534351145, Blast_Score=210, Evalue=3e-54,
Organism=Drosophila melanogaster, GI19920408, Length=262, Percent_Identity=41.2213740458015, Blast_Score=210, Evalue=3e-54,
Organism=Drosophila melanogaster, GI45554047, Length=163, Percent_Identity=58.8957055214724, Blast_Score=210, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24660075, Length=230, Percent_Identity=43.4782608695652, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI281365776, Length=230, Percent_Identity=43.4782608695652, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI45552965, Length=230, Percent_Identity=43.4782608695652, Blast_Score=195, Evalue=9e-50,
Organism=Drosophila melanogaster, GI24652279, Length=273, Percent_Identity=36.6300366300366, Blast_Score=191, Evalue=9e-49,
Organism=Drosophila melanogaster, GI19921202, Length=225, Percent_Identity=41.3333333333333, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24649446, Length=254, Percent_Identity=37.4015748031496, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24640100, Length=253, Percent_Identity=37.9446640316205, Blast_Score=185, Evalue=9e-47,
Organism=Drosophila melanogaster, GI17738151, Length=246, Percent_Identity=39.8373983739837, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI281361487, Length=244, Percent_Identity=39.7540983606557, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI18860063, Length=251, Percent_Identity=37.4501992031873, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24663015, Length=253, Percent_Identity=37.5494071146245, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24656825, Length=239, Percent_Identity=39.3305439330544, Blast_Score=169, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24656820, Length=239, Percent_Identity=38.9121338912134, Blast_Score=169, Evalue=7e-42,
Organism=Drosophila melanogaster, GI281363136, Length=235, Percent_Identity=38.7234042553192, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI78707192, Length=235, Percent_Identity=38.7234042553192, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI21355121, Length=212, Percent_Identity=36.3207547169811, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI20129529, Length=276, Percent_Identity=36.231884057971, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI18859657, Length=238, Percent_Identity=39.4957983193277, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24581396, Length=232, Percent_Identity=40.0862068965517, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24644145, Length=238, Percent_Identity=35.2941176470588, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17864540, Length=257, Percent_Identity=35.408560311284, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281360136, Length=228, Percent_Identity=35.5263157894737, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24644411, Length=228, Percent_Identity=35.5263157894737, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281360144, Length=228, Percent_Identity=35.5263157894737, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281360140, Length=228, Percent_Identity=35.5263157894737, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281360146, Length=230, Percent_Identity=36.0869565217391, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281360138, Length=230, Percent_Identity=36.0869565217391, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281360142, Length=230, Percent_Identity=36.0869565217391, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21357333, Length=230, Percent_Identity=36.0869565217391, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571849, Length=231, Percent_Identity=39.8268398268398, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28571847, Length=231, Percent_Identity=39.8268398268398, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28573010, Length=257, Percent_Identity=34.6303501945525, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI20129423, Length=239, Percent_Identity=33.4728033472803, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24639486, Length=196, Percent_Identity=35.7142857142857, Blast_Score=106, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 72476; Mature: 72344

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKNLILWLVIAVVLMSVFQSFGPGDSSGRSIDYTTFVKEVGNSQVQEATFNNREIKVMK
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCEEEEEE
RDGTRYVTYMPVFQDPKLLDDLINQNVIVKGTPPEEQSLLESIFISWFPMILLIGVWIFF
CCCCEEEEEECCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MRQMQGGGGKGAMSFGKSKAKMMTEEQIKTTFDDVAGCDEAKEDVKELVDYLREPSRFQK
HHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHH
LGGKIPTGVLLVGPPGTGKTLIAKAIAGEAKVPFFSISGSDFVEMFVGVGASRVRDMFEQ
HCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCHHHHHHHHHH
AKKSSPCIIFIDEIDAVGRQRGAGVGGGNDEREQTLNQMLVEMDGFEGNEGIIVIAATNR
HHCCCCEEEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
PDVLDAALLRPGRFDRQVVVGLPDIRGREQILQVHMRKVPLGAGVEPSLIARGTPGFSGA
CCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCH
DLANLVNEAALFAARGNKRVVSMVEFELAKDKIMMGAERKSMVMSEETKESTAYHEAGHA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IVGRLVPEHDPVYKVSIIPRGRALGVTMYLPEQDRISMNRQHLESMISSLYGGRLAEELI
HHHHCCCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YGVDKVSTGASNDIERATDIARKMVTQWGFSDALGPLLYAEDQGDPFSGHGGSHQPKHVS
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCC
PETLQLIDAEIRTIIDRNYARARQILEDNMDIMHAMKDALMKFETIDAGQIDDLMDRKAD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHC
IREPQGWGDNNPQPQAKTEAPVEKEETESKAEEKVEETKEQPTSTDETKNDSESSEK
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKNLILWLVIAVVLMSVFQSFGPGDSSGRSIDYTTFVKEVGNSQVQEATFNNREIKVMK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCEEEEEE
RDGTRYVTYMPVFQDPKLLDDLINQNVIVKGTPPEEQSLLESIFISWFPMILLIGVWIFF
CCCCEEEEEECCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MRQMQGGGGKGAMSFGKSKAKMMTEEQIKTTFDDVAGCDEAKEDVKELVDYLREPSRFQK
HHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHH
LGGKIPTGVLLVGPPGTGKTLIAKAIAGEAKVPFFSISGSDFVEMFVGVGASRVRDMFEQ
HCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCHHHHHHHHHH
AKKSSPCIIFIDEIDAVGRQRGAGVGGGNDEREQTLNQMLVEMDGFEGNEGIIVIAATNR
HHCCCCEEEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
PDVLDAALLRPGRFDRQVVVGLPDIRGREQILQVHMRKVPLGAGVEPSLIARGTPGFSGA
CCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCH
DLANLVNEAALFAARGNKRVVSMVEFELAKDKIMMGAERKSMVMSEETKESTAYHEAGHA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IVGRLVPEHDPVYKVSIIPRGRALGVTMYLPEQDRISMNRQHLESMISSLYGGRLAEELI
HHHHCCCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YGVDKVSTGASNDIERATDIARKMVTQWGFSDALGPLLYAEDQGDPFSGHGGSHQPKHVS
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCC
PETLQLIDAEIRTIIDRNYARARQILEDNMDIMHAMKDALMKFETIDAGQIDDLMDRKAD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHC
IREPQGWGDNNPQPQAKTEAPVEKEETESKAEEKVEETKEQPTSTDETKNDSESSEK
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA