Click here to switch to the map view.

The map label for this gene is rdgB [C]

Identifier: 59711032

GI number: 59711032

Start: 455296

End: 455892

Strand: Reverse

Name: rdgB [C]

Synonym: VF_0425

Alternate gene names: 59711032

Gene position: 455892-455296 (Counterclockwise)

Preceding gene: 59711033

Following gene: 59711031

Centisome position: 15.73

GC content: 42.21

Gene sequence:

>597_bases
ATGAGTAAAATCGTATTAGCAACGGGCAACCAAGGTAAAGTTCGTGAAATGGCCGACATCCTAGCGGATTTTGGTTTTGA
TGTAGTAGCACAAAGCGAATATAACGTCTCTGATGTAGCTGAAACTGGTACAACATTCATTGAAAACGCTATCATCAAAG
CGCGTCATGCAGCAAAAGAAACGGGCTTACCTGCTATTGCTGATGATTCAGGTTTAGAAGTTGATGCGCTAAATGGCGCA
CCGGGTGTTTACTCTGCTCGTTATTCTGGTGAAGGTGCTACGGATCAAAAGAACATTGATAAAATGCTAGCAGCGATGGA
AGGCATTCCTGCTGAAAAACGTACTGCTCGCTTCCATTGTGTTTTAGTTCTGATGAAACATGAAAACGATCCAACACCAT
TGATTTGTCATGGAACATGGGAAGGTCATATCACGACAGAGCAAAAAGGTGAAAACGGCTTCGGTTATGATCCTATTTTC
TGGGTAAGTGAAGATAACTGTTCATCTGCTGAACTTGAACCTGCACGTAAAAAACAACTATCTCACCGTGGCCAAGCTCT
GAAAAAGCTCTTTGCAGCATTAAAAGAAGGTCAGTAA

Upstream 100 bases:

>100_bases
GAAACCTTTCGCTTTGATATTGATGTCTCTGCTGGCACTAAAGGCGCAGGCAAGTTAAAGTTCAACCAAAAGTTTTACGT
AGAAGAGTAAGAGAACCATT

Downstream 100 bases:

>100_bases
GTAATGCTTATTCCACCACCTCTAAGCCTATATATTCATATTCCTTGGTGCATTCAGAAATGTCCATATTGTGACTTTAA
CTCTCATGCTTTAAAAGCTG

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSKIVLATGNQGKVREMADILADFGFDVVAQSEYNVSDVAETGTTFIENAIIKARHAAKETGLPAIADDSGLEVDALNGA
PGVYSARYSGEGATDQKNIDKMLAAMEGIPAEKRTARFHCVLVLMKHENDPTPLICHGTWEGHITTEQKGENGFGYDPIF
WVSEDNCSSAELEPARKKQLSHRGQALKKLFAALKEGQ

Sequences:

>Translated_198_residues
MSKIVLATGNQGKVREMADILADFGFDVVAQSEYNVSDVAETGTTFIENAIIKARHAAKETGLPAIADDSGLEVDALNGA
PGVYSARYSGEGATDQKNIDKMLAAMEGIPAEKRTARFHCVLVLMKHENDPTPLICHGTWEGHITTEQKGENGFGYDPIF
WVSEDNCSSAELEPARKKQLSHRGQALKKLFAALKEGQ
>Mature_197_residues
SKIVLATGNQGKVREMADILADFGFDVVAQSEYNVSDVAETGTTFIENAIIKARHAAKETGLPAIADDSGLEVDALNGAP
GVYSARYSGEGATDQKNIDKMLAAMEGIPAEKRTARFHCVLVLMKHENDPTPLICHGTWEGHITTEQKGENGFGYDPIFW
VSEDNCSSAELEPARKKQLSHRGQALKKLFAALKEGQ

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=197, Percent_Identity=63.4517766497462, Blast_Score=269, Evalue=1e-73,
Organism=Drosophila melanogaster, GI19920712, Length=192, Percent_Identity=31.25, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21450; Mature: 21319

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIVLATGNQGKVREMADILADFGFDVVAQSEYNVSDVAETGTTFIENAIIKARHAAKE
CCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TGLPAIADDSGLEVDALNGAPGVYSARYSGEGATDQKNIDKMLAAMEGIPAEKRTARFHC
CCCCEEECCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHCEEEE
VLVLMKHENDPTPLICHGTWEGHITTEQKGENGFGYDPIFWVSEDNCSSAELEPARKKQL
EEEEEECCCCCCCEEEECCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHH
SHRGQALKKLFAALKEGQ
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKIVLATGNQGKVREMADILADFGFDVVAQSEYNVSDVAETGTTFIENAIIKARHAAKE
CEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TGLPAIADDSGLEVDALNGAPGVYSARYSGEGATDQKNIDKMLAAMEGIPAEKRTARFHC
CCCCEEECCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHCEEEE
VLVLMKHENDPTPLICHGTWEGHITTEQKGENGFGYDPIFWVSEDNCSSAELEPARKKQL
EEEEEECCCCCCCEEEECCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHH
SHRGQALKKLFAALKEGQ
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA