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The map label for this gene is alr [H]

Identifier: 59710909

GI number: 59710909

Start: 310875

End: 311957

Strand: Direct

Name: alr [H]

Synonym: VF_0302

Alternate gene names: 59710909

Gene position: 310875-311957 (Clockwise)

Preceding gene: 59710908

Following gene: 59710910

Centisome position: 10.73

GC content: 43.21

Gene sequence:

>1083_bases
ATGAGTTATATGAAAGCGGCCACAGCGCAGATTGATATGTCTGCACTTGCCCACAATTTGCAAAAGATTAAACAACAAGC
TCCGAGTAGTAAATTACTGGCTGTTGTAAAAGCAAATGGGTATGGCCATGGATTGCTGAATATCGCTAAAGGAGCTCAAG
GAGCTGATGCATTTGGTGTCGCTCGTATTGAAGAGGCGCTGCAGCTTCGAGCTGGCGGTATTGTAAAACCTATTTTATTA
CTTGAAGGGTTCTACTCAGCAGGTGACTTGCCTATTTTGGTGACTAATAACATTCAAACGGCGATTCATTGTAAAGAGCA
GTTAGAAGCATTAGAAAGTACAGACTTAGAATTTCCAGTCGTTGCTTGGTTAAAAGTAGATTCAGGTATGCACCGTTTAG
GTATTCGTCCTGAAGAGTTTCAAGAATATGTTGATAGACTACATGCTTGTAAGAATGTCGCTAAACCTTTGCGTTATATG
AGCCACTTTGGCTGTGCGGATGAACTTGATAGTTCAACGACAACAGAGCAAATCGATACCTTTATGTCGCTAACAAAAGG
GTGTCAGGGAGAGCGTTCTCTTGCTGCATCTGCAGGCTTATTAGCTTGGCCTGATAGTCGTTTAGATTGGGTTCGTCCTG
GCATTATTATGTATGGCGTTTCTCCATTTGCAGAACAATCAGCACAAGAGTTGGGTTATTTGCCTACGATGACTCTTACC
TCTCACTTGATCGCAGTTCGTGATGTAAAAGCGGGTGAAAGTGTTGGTTATGGTGCCATTTGGACCAGTGAGCGTGATAC
TAAAATTGGTGTTATTGCGATTGGCTATGGTGATGGGTACCCTCGAACGGCTCCAAATGGTACGCCTGTGTTAGTTAATG
GTCGTAAAGTCCCTATTGCGGGTCGAGTGTCTATGGACATGTTGACCGTTGATTTAGGTCCAGATGCTCAAGATAAAGTG
GGAGATGAAGCCATTTTATGGGGACGAGATCTGCCTTCTGAAGAAGTCGCAGAGCATATTGGAACTATTGCCTACGAGTT
AGTGACTAAATTAACATCACGTGTGCAAATGCAATACACCTAA

Upstream 100 bases:

>100_bases
CGGTCCTATCGGTTCTGTTAGCTTGACTTTCCAAGGGCAATTTTCTCGTTTTGATAATTACGCAGGCCCTGCGTTTGATG
ATGAATAATAAGGCTGAATC

Downstream 100 bases:

>100_bases
TGAGAGTCTTCTTGAATTCATTTTCTTTTAAAAGCGCTACTGGTCTAGCGCTTTTTCTTATTTCCCACTTGGCTTTTTCA
GAAAGCGATATTTGGCCAAC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MSYMKAATAQIDMSALAHNLQKIKQQAPSSKLLAVVKANGYGHGLLNIAKGAQGADAFGVARIEEALQLRAGGIVKPILL
LEGFYSAGDLPILVTNNIQTAIHCKEQLEALESTDLEFPVVAWLKVDSGMHRLGIRPEEFQEYVDRLHACKNVAKPLRYM
SHFGCADELDSSTTTEQIDTFMSLTKGCQGERSLAASAGLLAWPDSRLDWVRPGIIMYGVSPFAEQSAQELGYLPTMTLT
SHLIAVRDVKAGESVGYGAIWTSERDTKIGVIAIGYGDGYPRTAPNGTPVLVNGRKVPIAGRVSMDMLTVDLGPDAQDKV
GDEAILWGRDLPSEEVAEHIGTIAYELVTKLTSRVQMQYT

Sequences:

>Translated_360_residues
MSYMKAATAQIDMSALAHNLQKIKQQAPSSKLLAVVKANGYGHGLLNIAKGAQGADAFGVARIEEALQLRAGGIVKPILL
LEGFYSAGDLPILVTNNIQTAIHCKEQLEALESTDLEFPVVAWLKVDSGMHRLGIRPEEFQEYVDRLHACKNVAKPLRYM
SHFGCADELDSSTTTEQIDTFMSLTKGCQGERSLAASAGLLAWPDSRLDWVRPGIIMYGVSPFAEQSAQELGYLPTMTLT
SHLIAVRDVKAGESVGYGAIWTSERDTKIGVIAIGYGDGYPRTAPNGTPVLVNGRKVPIAGRVSMDMLTVDLGPDAQDKV
GDEAILWGRDLPSEEVAEHIGTIAYELVTKLTSRVQMQYT
>Mature_359_residues
SYMKAATAQIDMSALAHNLQKIKQQAPSSKLLAVVKANGYGHGLLNIAKGAQGADAFGVARIEEALQLRAGGIVKPILLL
EGFYSAGDLPILVTNNIQTAIHCKEQLEALESTDLEFPVVAWLKVDSGMHRLGIRPEEFQEYVDRLHACKNVAKPLRYMS
HFGCADELDSSTTTEQIDTFMSLTKGCQGERSLAASAGLLAWPDSRLDWVRPGIIMYGVSPFAEQSAQELGYLPTMTLTS
HLIAVRDVKAGESVGYGAIWTSERDTKIGVIAIGYGDGYPRTAPNGTPVLVNGRKVPIAGRVSMDMLTVDLGPDAQDKVG
DEAILWGRDLPSEEVAEHIGTIAYELVTKLTSRVQMQYT

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=357, Percent_Identity=59.3837535014006, Blast_Score=448, Evalue=1e-127,
Organism=Escherichia coli, GI1787439, Length=349, Percent_Identity=42.6934097421203, Blast_Score=273, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39005; Mature: 38874

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYMKAATAQIDMSALAHNLQKIKQQAPSSKLLAVVKANGYGHGLLNIAKGAQGADAFGV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHCCCCCCCHHHH
ARIEEALQLRAGGIVKPILLLEGFYSAGDLPILVTNNIQTAIHCKEQLEALESTDLEFPV
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCE
VAWLKVDSGMHRLGIRPEEFQEYVDRLHACKNVAKPLRYMSHFGCADELDSSTTTEQIDT
EEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHH
FMSLTKGCQGERSLAASAGLLAWPDSRLDWVRPGIIMYGVSPFAEQSAQELGYLPTMTLT
HHHHHHCCCCCHHHHHCCCEEECCCCCCCHHCCCEEEECCCHHHHHHHHHHCCCCHHHHH
SHLIAVRDVKAGESVGYGAIWTSERDTKIGVIAIGYGDGYPRTAPNGTPVLVNGRKVPIA
HHHHHEEECCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCEEEECCEEECEE
GRVSMDMLTVDLGPDAQDKVGDEAILWGRDLPSEEVAEHIGTIAYELVTKLTSRVQMQYT
CCCEEEEEEEECCCCCHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure 
SYMKAATAQIDMSALAHNLQKIKQQAPSSKLLAVVKANGYGHGLLNIAKGAQGADAFGV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHCCCCCCCHHHH
ARIEEALQLRAGGIVKPILLLEGFYSAGDLPILVTNNIQTAIHCKEQLEALESTDLEFPV
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCE
VAWLKVDSGMHRLGIRPEEFQEYVDRLHACKNVAKPLRYMSHFGCADELDSSTTTEQIDT
EEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHH
FMSLTKGCQGERSLAASAGLLAWPDSRLDWVRPGIIMYGVSPFAEQSAQELGYLPTMTLT
HHHHHHCCCCCHHHHHCCCEEECCCCCCCHHCCCEEEECCCHHHHHHHHHHCCCCHHHHH
SHLIAVRDVKAGESVGYGAIWTSERDTKIGVIAIGYGDGYPRTAPNGTPVLVNGRKVPIA
HHHHHEEECCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCEEEECCEEECEE
GRVSMDMLTVDLGPDAQDKVGDEAILWGRDLPSEEVAEHIGTIAYELVTKLTSRVQMQYT
CCCEEEEEEEECCCCCHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA