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The map label for this gene is glpX [H]

Identifier: 59710816

GI number: 59710816

Start: 232010

End: 233017

Strand: Reverse

Name: glpX [H]

Synonym: VF_0209

Alternate gene names: 59710816

Gene position: 233017-232010 (Counterclockwise)

Preceding gene: 59710818

Following gene: 59710815

Centisome position: 8.04

GC content: 43.75

Gene sequence:

>1008_bases
ATGAAACGCGATTTAGCAATGGCTTTTTCTCGAGTTACTGAAGGTGCCGCACTGGCTGGTTACAAATGGCTTGGCCGTGG
TGATAAAAACGCTGCTGACGGTGCTGCTGTTGAAGTAATGCGTACTCTTCTGAACAAAACTGATATCAGTGGTGAAATTG
TTATTGGTGAAGGTGAGATCGATGATGCACCTATGCTATACATCGGTGAAAACGTAGGTACAGGTGGCGATGCTGTTGAT
ATCGCGGTTGATCCAATCGAAGGCACTCGTATGACAGCAATGGGTCAATCAAACGCACTTGCCGTATTGGCTGCTGGTGA
AAAAGGTAGCTTCTTAAAAGCACCTGATATGTACATGGAAAAATTGGTGGTTGGTCCTGGTGCAAAAGGCGCAATTGATT
TAAGTCTTTCTCTAGAAGACAACCTAGTAAATATTGCAAAAGCATTAGGTAAACCATTAGAAACGCTTGTTGTGACAACA
CTGGCTAAACCTCGTCATGATGAAGTAATTGCAAACATGCAGAAAATGGGTGTTCGTGTATTTGCTGTGCCAGATGGTGA
TGTTGCAGCTTCTATTCTAACTTGTATGCCTGATAGCGAAGTGGACGTTATGTACTGTATCGGTGGAGCACCTGAAGGTG
TAGTTTCTGCTGCAGTTATCCGTGCACTAGATGGCGACATGCAAGCACGCCTTCTTCCTCGTCATGAAGTTAAAGGCGAT
ACAGAAGAAAACCGTATCCACGGTGAAGCTGAACTAAAACGCTGCGAAGAAATGGGCGTAAAAGCGAACGTTATCTTAAA
GATGACAGACATGGCACGCAGTGATGATGTTGTATTTGCAGCAACTGGTATCACTAAAGGTGACCTACTAGAAGGCATTA
CTCGCCAAGGTAATATTGCGACAACTGAAACGCTACTTATCCGTGGTCGTTGTCGTACGATTCGTCGTATTAAGTCGATT
CACTACTTAGAGCGTAAAGACGCTGAAGTTAGAGATATTATTCTTTAA

Upstream 100 bases:

>100_bases
AAAAAATTTCATTCTCGCCTGAAAAAGCAAACGTTTCCCTTTTTGTTATGCTAAAATCCCCCTCGATTTTTACTTATTCA
TCGATTTATTCGGAGCAATT

Downstream 100 bases:

>100_bases
GAGCAGGGACTAGAGGCGAGGACGCTTCGCTTAAGGAGCGAGGAAGAGCCGAGGTCTGCGATAAATTTGAAACCGTGGAT
GTGAAAGCATCTGCGGTTTT

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKRDLAMAFSRVTEGAALAGYKWLGRGDKNAADGAAVEVMRTLLNKTDISGEIVIGEGEIDDAPMLYIGENVGTGGDAVD
IAVDPIEGTRMTAMGQSNALAVLAAGEKGSFLKAPDMYMEKLVVGPGAKGAIDLSLSLEDNLVNIAKALGKPLETLVVTT
LAKPRHDEVIANMQKMGVRVFAVPDGDVAASILTCMPDSEVDVMYCIGGAPEGVVSAAVIRALDGDMQARLLPRHEVKGD
TEENRIHGEAELKRCEEMGVKANVILKMTDMARSDDVVFAATGITKGDLLEGITRQGNIATTETLLIRGRCRTIRRIKSI
HYLERKDAEVRDIIL

Sequences:

>Translated_335_residues
MKRDLAMAFSRVTEGAALAGYKWLGRGDKNAADGAAVEVMRTLLNKTDISGEIVIGEGEIDDAPMLYIGENVGTGGDAVD
IAVDPIEGTRMTAMGQSNALAVLAAGEKGSFLKAPDMYMEKLVVGPGAKGAIDLSLSLEDNLVNIAKALGKPLETLVVTT
LAKPRHDEVIANMQKMGVRVFAVPDGDVAASILTCMPDSEVDVMYCIGGAPEGVVSAAVIRALDGDMQARLLPRHEVKGD
TEENRIHGEAELKRCEEMGVKANVILKMTDMARSDDVVFAATGITKGDLLEGITRQGNIATTETLLIRGRCRTIRRIKSI
HYLERKDAEVRDIIL
>Mature_335_residues
MKRDLAMAFSRVTEGAALAGYKWLGRGDKNAADGAAVEVMRTLLNKTDISGEIVIGEGEIDDAPMLYIGENVGTGGDAVD
IAVDPIEGTRMTAMGQSNALAVLAAGEKGSFLKAPDMYMEKLVVGPGAKGAIDLSLSLEDNLVNIAKALGKPLETLVVTT
LAKPRHDEVIANMQKMGVRVFAVPDGDVAASILTCMPDSEVDVMYCIGGAPEGVVSAAVIRALDGDMQARLLPRHEVKGD
TEENRIHGEAELKRCEEMGVKANVILKMTDMARSDDVVFAATGITKGDLLEGITRQGNIATTETLLIRGRCRTIRRIKSI
HYLERKDAEVRDIIL

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=336, Percent_Identity=77.6785714285714, Blast_Score=526, Evalue=1e-151,
Organism=Escherichia coli, GI1789298, Length=318, Percent_Identity=57.5471698113208, Blast_Score=343, Evalue=8e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35806; Mature: 35806

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRDLAMAFSRVTEGAALAGYKWLGRGDKNAADGAAVEVMRTLLNKTDISGEIVIGEGEI
CCCHHHHHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
DDAPMLYIGENVGTGGDAVDIAVDPIEGTRMTAMGQSNALAVLAAGEKGSFLKAPDMYME
CCCCEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEECCCCCEECCCHHHHH
KLVVGPGAKGAIDLSLSLEDNLVNIAKALGKPLETLVVTTLAKPRHDEVIANMQKMGVRV
HHEECCCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCEEE
FAVPDGDVAASILTCMPDSEVDVMYCIGGAPEGVVSAAVIRALDGDMQARLLPRHEVKGD
EEECCCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEECCCHHCCCC
TEENRIHGEAELKRCEEMGVKANVILKMTDMARSDDVVFAATGITKGDLLEGITRQGNIA
CCHHCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHCCCCCCE
TTETLLIRGRCRTIRRIKSIHYLERKDAEVRDIIL
EEEEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MKRDLAMAFSRVTEGAALAGYKWLGRGDKNAADGAAVEVMRTLLNKTDISGEIVIGEGEI
CCCHHHHHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
DDAPMLYIGENVGTGGDAVDIAVDPIEGTRMTAMGQSNALAVLAAGEKGSFLKAPDMYME
CCCCEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEECCCCCEECCCHHHHH
KLVVGPGAKGAIDLSLSLEDNLVNIAKALGKPLETLVVTTLAKPRHDEVIANMQKMGVRV
HHEECCCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCEEE
FAVPDGDVAASILTCMPDSEVDVMYCIGGAPEGVVSAAVIRALDGDMQARLLPRHEVKGD
EEECCCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEECCCHHCCCC
TEENRIHGEAELKRCEEMGVKANVILKMTDMARSDDVVFAATGITKGDLLEGITRQGNIA
CCHHCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHCCCCCCE
TTETLLIRGRCRTIRRIKSIHYLERKDAEVRDIIL
EEEEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]