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The map label for this gene is uspA [H]

Identifier: 59710690

GI number: 59710690

Start: 96523

End: 96948

Strand: Reverse

Name: uspA [H]

Synonym: VF_0083

Alternate gene names: 59710690

Gene position: 96948-96523 (Counterclockwise)

Preceding gene: 59710695

Following gene: 59710688

Centisome position: 3.35

GC content: 38.73

Gene sequence:

>426_bases
ATGAGTTACCAACACATTCTTGTTGCTGTTGATTTAACAGAAGAGAGCAAGGCACTAGTAAGTAAAGCCGTTGGTCTTGC
AAAAGCGTTAGATGCTAAAGTTTCTTTTATTCATATTGATGTTAGCTATGCAGAGCTTTATACCGGTCTGATTGATATCA
ACCTAGCAGAAACACAACACCAAGCGATGGAAGCATCAAAAGAAGCGATGAAGCATCTGGTGGAATTTGCAGATTACCCT
ATCCACAAAACATTGGTAAGTAGTGGTGATTTAAGCAATGAATTAACCGAAGCTATCGAGAACCTTGATGTGAATCTAGT
GGTCTGTGGGCACCACCAGGATTTCTGGAGTAAATTACTGTCATCAACCAGACAAGTTATTAATACCTGTCCAATTGATG
TATTAGTGGTTCCGTTTAAAGATTAA

Upstream 100 bases:

>100_bases
CTATCAATCAGAACGAGATCTAAACGACAAAAAAAGAACAATTCTGGTGCTAATCTATAGTTATCAAATAATTCAATTTT
GAATTTAAAGGAGATATATC

Downstream 100 bases:

>100_bases
GCCATTGCGGCATTTACGTAGACATCGAAACGGTTCTTTTTCGTTTCAATCGCCATCGATGGTTTTTGATTATCTAACCA
CTCTGCGTAATCAGGGCGTT

Product: universal stress global response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MSYQHILVAVDLTEESKALVSKAVGLAKALDAKVSFIHIDVSYAELYTGLIDINLAETQHQAMEASKEAMKHLVEFADYP
IHKTLVSSGDLSNELTEAIENLDVNLVVCGHHQDFWSKLLSSTRQVINTCPIDVLVVPFKD

Sequences:

>Translated_141_residues
MSYQHILVAVDLTEESKALVSKAVGLAKALDAKVSFIHIDVSYAELYTGLIDINLAETQHQAMEASKEAMKHLVEFADYP
IHKTLVSSGDLSNELTEAIENLDVNLVVCGHHQDFWSKLLSSTRQVINTCPIDVLVVPFKD
>Mature_140_residues
SYQHILVAVDLTEESKALVSKAVGLAKALDAKVSFIHIDVSYAELYTGLIDINLAETQHQAMEASKEAMKHLVEFADYPI
HKTLVSSGDLSNELTEAIENLDVNLVVCGHHQDFWSKLLSSTRQVINTCPIDVLVVPFKD

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1789909, Length=141, Percent_Identity=56.7375886524823, Blast_Score=172, Evalue=7e-45,
Organism=Escherichia coli, GI1790358, Length=141, Percent_Identity=34.0425531914894, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI1788205, Length=140, Percent_Identity=35, Blast_Score=85, Evalue=2e-18,

Paralogues:

None

Copy number: 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 290 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4003 Molecules/Cell In: Growth Phase, G

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 15594; Mature: 15463

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQHILVAVDLTEESKALVSKAVGLAKALDAKVSFIHIDVSYAELYTGLIDINLAETQH
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEEEEEHHHHHHHHHHEEEHHHHHH
QAMEASKEAMKHLVEFADYPIHKTLVSSGDLSNELTEAIENLDVNLVVCGHHQDFWSKLL
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHH
SSTRQVINTCPIDVLVVPFKD
HHHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure 
SYQHILVAVDLTEESKALVSKAVGLAKALDAKVSFIHIDVSYAELYTGLIDINLAETQH
CCCEEEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEEEEEHHHHHHHHHHEEEHHHHHH
QAMEASKEAMKHLVEFADYPIHKTLVSSGDLSNELTEAIENLDVNLVVCGHHQDFWSKLL
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHH
SSTRQVINTCPIDVLVVPFKD
HHHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]