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The map label for this gene is tatD [H]

Identifier: 59710659

GI number: 59710659

Start: 59230

End: 59991

Strand: Reverse

Name: tatD [H]

Synonym: VF_0052

Alternate gene names: 59710659

Gene position: 59991-59230 (Counterclockwise)

Preceding gene: 59710661

Following gene: 59710650

Centisome position: 2.07

GC content: 39.37

Gene sequence:

>762_bases
ATGATAGATACTCACGCTCATATTTATGCAAAAGAATTTGATGAAGATAGAGATGCGGTTGTTCAGCGCGCACTAGAACA
AGGTATTAGCAAAATTCTACTACCTAACATCGATTTAGAATCTATCGAACCAATGCTCAAAACGGAAGCCGCATATCCTG
AGGTTTGCCATTCAATGATGGGATTACACCCTTGTTATGTGAACGCTGACGTGAAAGAAACCTTGGCAATCATTCACTCA
TGGTTTGAAAAGCATAATTTCATTGCGGTAGGTGAAATAGGTATTGACCTATACTGGGACAAAACCTTTAAAGCAGAACA
AGAGATGGCATTCATTACCCAATTAAATTGGGCAAAAGAGATGAAACTACCTGTTGTGATTCACACTCGTGACTCTATTG
AAGAAACATTAAGTCTATTAAAACAAGAACAAGATGGTTCATTATCTGGTGTTTTCCACTGCTTTGGTGGCTCAGTTGAT
GAAGCAAAAGCCATTAATGATTTAGGGTTTCATTTAGGCCTTGGTGGTGTGTCTACCTTTAAAAATGGCGGGATGGATAA
GATTATTCCTCATCTTGATATGGATTATTTAATCCTAGAAACCGATTGTCCTTATTTAGCACCGGTGCCACATCGTGGTA
AGCGAAATGAGCCTGCGTATACGCAGTTAGTTGCTCAAAGAGTGGCAGATTTACGTGAAATTAGTTTGGCTGATGTGGAT
GCAATTACGACGGCGAATGCGATGAAATTGTTTGGGGTTTAA

Upstream 100 bases:

>100_bases
GGCTAATCGTAGTCTTTCAAGTGACTTTTTCGTATAGATCTGATTTTTACTTTGAACTTGGTATGATAGAAGCCATTATT
TTTTGTTTTAGGGTTTCACC

Downstream 100 bases:

>100_bases
GAGATCGCTTTGCTTGAAGGTTTCAGGTTTCAGGTTTCAGGTTTCAGGTTTCAGGTTTCAGGTTTCAGGAAGAGCTTATA
CGCTTCGTTAACTAGAGACT

Product: DNase, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MIDTHAHIYAKEFDEDRDAVVQRALEQGISKILLPNIDLESIEPMLKTEAAYPEVCHSMMGLHPCYVNADVKETLAIIHS
WFEKHNFIAVGEIGIDLYWDKTFKAEQEMAFITQLNWAKEMKLPVVIHTRDSIEETLSLLKQEQDGSLSGVFHCFGGSVD
EAKAINDLGFHLGLGGVSTFKNGGMDKIIPHLDMDYLILETDCPYLAPVPHRGKRNEPAYTQLVAQRVADLREISLADVD
AITTANAMKLFGV

Sequences:

>Translated_253_residues
MIDTHAHIYAKEFDEDRDAVVQRALEQGISKILLPNIDLESIEPMLKTEAAYPEVCHSMMGLHPCYVNADVKETLAIIHS
WFEKHNFIAVGEIGIDLYWDKTFKAEQEMAFITQLNWAKEMKLPVVIHTRDSIEETLSLLKQEQDGSLSGVFHCFGGSVD
EAKAINDLGFHLGLGGVSTFKNGGMDKIIPHLDMDYLILETDCPYLAPVPHRGKRNEPAYTQLVAQRVADLREISLADVD
AITTANAMKLFGV
>Mature_253_residues
MIDTHAHIYAKEFDEDRDAVVQRALEQGISKILLPNIDLESIEPMLKTEAAYPEVCHSMMGLHPCYVNADVKETLAIIHS
WFEKHNFIAVGEIGIDLYWDKTFKAEQEMAFITQLNWAKEMKLPVVIHTRDSIEETLSLLKQEQDGSLSGVFHCFGGSVD
EAKAINDLGFHLGLGGVSTFKNGGMDKIIPHLDMDYLILETDCPYLAPVPHRGKRNEPAYTQLVAQRVADLREISLADVD
AITTANAMKLFGV

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=28.8389513108614, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=27.3408239700375, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=28.1021897810219, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI226061614, Length=252, Percent_Identity=26.1904761904762, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI14042943, Length=270, Percent_Identity=24.8148148148148, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI226061595, Length=231, Percent_Identity=26.4069264069264, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI225903439, Length=227, Percent_Identity=25.1101321585903, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=30.7392996108949, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=31.2741312741313, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=30.8880308880309, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=27.0992366412214, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=26.6903914590747, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24648690, Length=287, Percent_Identity=25.7839721254355, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586117, Length=269, Percent_Identity=26.0223048327138, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221330018, Length=269, Percent_Identity=26.0223048327138, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 28313; Mature: 28313

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTHAHIYAKEFDEDRDAVVQRALEQGISKILLPNIDLESIEPMLKTEAAYPEVCHSMM
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHH
GLHPCYVNADVKETLAIIHSWFEKHNFIAVGEIGIDLYWDKTFKAEQEMAFITQLNWAKE
CCCCEEECCCHHHHHHHHHHHHHHCCCEEEEEECEEEEECCCCCHHHHHHHHHHHHHHHH
MKLPVVIHTRDSIEETLSLLKQEQDGSLSGVFHCFGGSVDEAKAINDLGFHLGLGGVSTF
CCCCEEEECHHHHHHHHHHHHHCCCCCHHHHHEECCCCCHHHHHHHHHHHHHCCCCHHHH
KNGGMDKIIPHLDMDYLILETDCPYLAPVPHRGKRNEPAYTQLVAQRVADLREISLADVD
CCCCHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AITTANAMKLFGV
HHHHCCHHHCCCC
>Mature Secondary Structure
MIDTHAHIYAKEFDEDRDAVVQRALEQGISKILLPNIDLESIEPMLKTEAAYPEVCHSMM
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHH
GLHPCYVNADVKETLAIIHSWFEKHNFIAVGEIGIDLYWDKTFKAEQEMAFITQLNWAKE
CCCCEEECCCHHHHHHHHHHHHHHCCCEEEEEECEEEEECCCCCHHHHHHHHHHHHHHHH
MKLPVVIHTRDSIEETLSLLKQEQDGSLSGVFHCFGGSVDEAKAINDLGFHLGLGGVSTF
CCCCEEEECHHHHHHHHHHHHHCCCCCHHHHHEECCCCCHHHHHHHHHHHHHCCCCHHHH
KNGGMDKIIPHLDMDYLILETDCPYLAPVPHRGKRNEPAYTQLVAQRVADLREISLADVD
CCCCHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AITTANAMKLFGV
HHHHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]