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The map label for this gene is map [H]

Identifier: 58617582

GI number: 58617582

Start: 1367280

End: 1368080

Strand: Reverse

Name: map [H]

Synonym: ERGA_CDS_08550

Alternate gene names: 58617582

Gene position: 1368080-1367280 (Counterclockwise)

Preceding gene: 58617584

Following gene: 58617581

Centisome position: 91.21

GC content: 33.08

Gene sequence:

>801_bases
ATGAGTAATTTTAATTCTGATATAACTATTTATAGCAAGGAAGATTTTCAATATATGCATAATGCTGGAAGACTTGCAGC
TAAAGTTTTGGATTTTATTATTCCGTATGTACAGCCTGGAGTTTCTACTAATAAACTAAATGATTTATGTCATGATTTTA
TTATCAATTCTGGAGCAATTCCAGCACCATTGGGATATAGAGGATATCCGAAGTCCATATGTACTTCCAAGAATTTTGTT
GTATGTCACGGAATACCAGATGATTTACCTTTAAAAGATGGTGATATTTTGAACATAGATGTTACTGTTATATTAGATGG
TTGGTATGGAGATACCAGTAGAATGTATTGGGTTGGTGAACCATCAATTAAAGCAAAACGTCTATGTGAAGCTACATATA
ATGCGTTAAATGTAGCAATTGCTCAAGTATTTCCTGGGCAAAAGCTTAATCAAATTGGATTGGCTATCGAAAGAGAAATA
AAAAAATATGGGTATTCAATAGTAAGAGATTACTGTGGTCATGGTTTAGGTCGTGTGTTTCATGATAAGCCTAGTGTGGT
ACATTATTATGATGAAAATGATCCAGTTGTCATTAGAGAGGGAATGTTTTTTACGATAGAACCAATGATCAATCTTGGTA
AACACCATACTGTTCTTAGTAAGGAAGATGGTTGGACTGTTAGAACAAGAGATTTTTCTTTATCTGCTCAGTTCGAACAT
TCTTTAGGTGTAACTGAGAATGGTGTAGAAATATTTACCTTATCTCCAAAGAATTTGCATTATCCACCTTATGTATGTTG
A

Upstream 100 bases:

>100_bases
ATGAGTAGTTCGTGTTTTTGAGAAAATGATTATTTTTATGAAGTAAATAATTATATTATTGAGTATTATGATATTAACAA
AAAAAATTTGTTAGGAAATT

Downstream 100 bases:

>100_bases
TTTATAATGAATACTATAGCCTCTTTATTTAATAATGCTGTTGATTTTTTAAATAACCATAATATAGACAATCCAAAGCG
TGATGTAGAAGTCATTATAA

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MSNFNSDITIYSKEDFQYMHNAGRLAAKVLDFIIPYVQPGVSTNKLNDLCHDFIINSGAIPAPLGYRGYPKSICTSKNFV
VCHGIPDDLPLKDGDILNIDVTVILDGWYGDTSRMYWVGEPSIKAKRLCEATYNALNVAIAQVFPGQKLNQIGLAIEREI
KKYGYSIVRDYCGHGLGRVFHDKPSVVHYYDENDPVVIREGMFFTIEPMINLGKHHTVLSKEDGWTVRTRDFSLSAQFEH
SLGVTENGVEIFTLSPKNLHYPPYVC

Sequences:

>Translated_266_residues
MSNFNSDITIYSKEDFQYMHNAGRLAAKVLDFIIPYVQPGVSTNKLNDLCHDFIINSGAIPAPLGYRGYPKSICTSKNFV
VCHGIPDDLPLKDGDILNIDVTVILDGWYGDTSRMYWVGEPSIKAKRLCEATYNALNVAIAQVFPGQKLNQIGLAIEREI
KKYGYSIVRDYCGHGLGRVFHDKPSVVHYYDENDPVVIREGMFFTIEPMINLGKHHTVLSKEDGWTVRTRDFSLSAQFEH
SLGVTENGVEIFTLSPKNLHYPPYVC
>Mature_265_residues
SNFNSDITIYSKEDFQYMHNAGRLAAKVLDFIIPYVQPGVSTNKLNDLCHDFIINSGAIPAPLGYRGYPKSICTSKNFVV
CHGIPDDLPLKDGDILNIDVTVILDGWYGDTSRMYWVGEPSIKAKRLCEATYNALNVAIAQVFPGQKLNQIGLAIEREIK
KYGYSIVRDYCGHGLGRVFHDKPSVVHYYDENDPVVIREGMFFTIEPMINLGKHHTVLSKEDGWTVRTRDFSLSAQFEHS
LGVTENGVEIFTLSPKNLHYPPYVC

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=249, Percent_Identity=42.9718875502008, Blast_Score=210, Evalue=8e-55,
Organism=Homo sapiens, GI40385867, Length=255, Percent_Identity=40, Blast_Score=187, Evalue=1e-47,
Organism=Escherichia coli, GI1786364, Length=249, Percent_Identity=55.8232931726908, Blast_Score=287, Evalue=5e-79,
Organism=Caenorhabditis elegans, GI71996291, Length=247, Percent_Identity=41.2955465587045, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6323273, Length=253, Percent_Identity=43.0830039525692, Blast_Score=215, Evalue=7e-57,
Organism=Drosophila melanogaster, GI21355531, Length=257, Percent_Identity=43.579766536965, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24583427, Length=244, Percent_Identity=42.6229508196721, Blast_Score=201, Evalue=5e-52,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29972; Mature: 29840

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFNSDITIYSKEDFQYMHNAGRLAAKVLDFIIPYVQPGVSTNKLNDLCHDFIINSGAI
CCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
PAPLGYRGYPKSICTSKNFVVCHGIPDDLPLKDGDILNIDVTVILDGWYGDTSRMYWVGE
CCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEECC
PSIKAKRLCEATYNALNVAIAQVFPGQKLNQIGLAIEREIKKYGYSIVRDYCGHGLGRVF
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHC
HDKPSVVHYYDENDPVVIREGMFFTIEPMINLGKHHTVLSKEDGWTVRTRDFSLSAQFEH
CCCCCEEEEECCCCCEEEECCCEEEEEHHHCCCCCCEEEECCCCCEEEEECEEEEEEECC
SLGVTENGVEIFTLSPKNLHYPPYVC
CCCCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SNFNSDITIYSKEDFQYMHNAGRLAAKVLDFIIPYVQPGVSTNKLNDLCHDFIINSGAI
CCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
PAPLGYRGYPKSICTSKNFVVCHGIPDDLPLKDGDILNIDVTVILDGWYGDTSRMYWVGE
CCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEECC
PSIKAKRLCEATYNALNVAIAQVFPGQKLNQIGLAIEREIKKYGYSIVRDYCGHGLGRVF
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHC
HDKPSVVHYYDENDPVVIREGMFFTIEPMINLGKHHTVLSKEDGWTVRTRDFSLSAQFEH
CCCCCEEEEECCCCCEEEECCCEEEEEHHHCCCCCCEEEECCCCCEEEEECEEEEEEECC
SLGVTENGVEIFTLSPKNLHYPPYVC
CCCCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]