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The map label for this gene is rnd [H]

Identifier: 58617449

GI number: 58617449

Start: 1144604

End: 1145773

Strand: Reverse

Name: rnd [H]

Synonym: ERGA_CDS_07220

Alternate gene names: 58617449

Gene position: 1145773-1144604 (Counterclockwise)

Preceding gene: 58617450

Following gene: 58617443

Centisome position: 76.39

GC content: 27.69

Gene sequence:

>1170_bases
ATGAAAAGTATGTTGATTGATACTACTGGTAAATTGCAGGATGTATGTAGTCAATTGCTTATGTCATGTCCTAAATTTAT
TGCAGTAGATACTGAATTTATCAGAAATTGTAATGAATACTATCCTAGATTATCTTTGATACAAATTGCCTGGAGTAAAG
GAAAATGTGTTATTGATGTTCTGGCAGATGATATAGATTTATCTGTTTTGGAATCTATTTTTTATAATAAAGAGATAGTC
AAGATCTTTCATGATTGTAAACAAGATATAGATGCATTATTAACAAAATTTCCAAGAATTCCTTATCCTATTTTTGATAG
TCAAATTGCTGCTATGTTTTGTGCCTATTATGATAATGCTGTGGGATATTCAAAGTTAGTTGCACAATTTTTAGATGTTT
CATTAGATAAATTAACTCTAAAACGATCTAACTGGCTAATGCGTCCGTTATCTGATGATAAGATTCAGTATGCACTTGAT
GATGTTGTATATTTATATGAGTTATACCAGGTACTATATGATAATCTTATATCTTCTAAAAGGTTGTTATGGTTTTTAGA
AGAAATGAGTAATATTGTCAAACAGGAGGCAAGTTATGGTAACATATATGACATTTCTGATTTTCCTTCAGAAGTGACAA
AGGATGAGATTATTATTAGTTGGTCTATTGTTGAATGGAGAGAAAAGTTAGCAAAGTATTTTAATGTTAATCGTGATTTT
GTATTAAAAAATAAAGCAATACCATACTTAGCTAAAGATCTTGTCGGAAAAAGTGATATTAGTATTTTAAAGAAGTACAT
TAAAAAAGAGTATTTATTGCATGATACAACGTTTGATGTTTTTCAAATTATTAGTAATAATCAATCTATTGATGTTGGTG
GTTTGTCTAGTGTAACTTCTAATAATAATAAGTCAGTTTTAAATATACTCTTAATATTATTATACAATATTTGTTATGAG
AATAATATATCACAAAAGTTGGTGTGTTCTAAAGGTAGTTTAATCAGGTTTCTTAATGGTAAGTCTAGTTATGTAATGAC
AGGTTGGAGATATGAGTTTTTTGGGTGTAAAATTGAAAAATTTATGCAAGGAAAATCAAAAATTATAGTATCTGCTCAAG
CATTAAATAATCAGTGTGTAGACATTGTTACTACTTTATCAGAGATGTAA

Upstream 100 bases:

>100_bases
TAATTATTTTATAAAAATTTAGATCAGTGTGTATGTAAATTAGTTGTATGTAGTGAAATTGCATTATAGATAATAAGTGT
ATGTTAAATGATAAAGAGGA

Downstream 100 bases:

>100_bases
ATAAGTAATTGATTATGTAAATTAATTGTTTTAGCAGTTTCCAGTTTAGGTAAATGAATAAGGTTTTTATTATTGCTGTT
CTTAAGGTTGTTTAAATTTT

Product: ribonuclease D

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKSMLIDTTGKLQDVCSQLLMSCPKFIAVDTEFIRNCNEYYPRLSLIQIAWSKGKCVIDVLADDIDLSVLESIFYNKEIV
KIFHDCKQDIDALLTKFPRIPYPIFDSQIAAMFCAYYDNAVGYSKLVAQFLDVSLDKLTLKRSNWLMRPLSDDKIQYALD
DVVYLYELYQVLYDNLISSKRLLWFLEEMSNIVKQEASYGNIYDISDFPSEVTKDEIIISWSIVEWREKLAKYFNVNRDF
VLKNKAIPYLAKDLVGKSDISILKKYIKKEYLLHDTTFDVFQIISNNQSIDVGGLSSVTSNNNKSVLNILLILLYNICYE
NNISQKLVCSKGSLIRFLNGKSSYVMTGWRYEFFGCKIEKFMQGKSKIIVSAQALNNQCVDIVTTLSEM

Sequences:

>Translated_389_residues
MKSMLIDTTGKLQDVCSQLLMSCPKFIAVDTEFIRNCNEYYPRLSLIQIAWSKGKCVIDVLADDIDLSVLESIFYNKEIV
KIFHDCKQDIDALLTKFPRIPYPIFDSQIAAMFCAYYDNAVGYSKLVAQFLDVSLDKLTLKRSNWLMRPLSDDKIQYALD
DVVYLYELYQVLYDNLISSKRLLWFLEEMSNIVKQEASYGNIYDISDFPSEVTKDEIIISWSIVEWREKLAKYFNVNRDF
VLKNKAIPYLAKDLVGKSDISILKKYIKKEYLLHDTTFDVFQIISNNQSIDVGGLSSVTSNNNKSVLNILLILLYNICYE
NNISQKLVCSKGSLIRFLNGKSSYVMTGWRYEFFGCKIEKFMQGKSKIIVSAQALNNQCVDIVTTLSEM
>Mature_389_residues
MKSMLIDTTGKLQDVCSQLLMSCPKFIAVDTEFIRNCNEYYPRLSLIQIAWSKGKCVIDVLADDIDLSVLESIFYNKEIV
KIFHDCKQDIDALLTKFPRIPYPIFDSQIAAMFCAYYDNAVGYSKLVAQFLDVSLDKLTLKRSNWLMRPLSDDKIQYALD
DVVYLYELYQVLYDNLISSKRLLWFLEEMSNIVKQEASYGNIYDISDFPSEVTKDEIIISWSIVEWREKLAKYFNVNRDF
VLKNKAIPYLAKDLVGKSDISILKKYIKKEYLLHDTTFDVFQIISNNQSIDVGGLSSVTSNNNKSVLNILLILLYNICYE
NNISQKLVCSKGSLIRFLNGKSSYVMTGWRYEFFGCKIEKFMQGKSKIIVSAQALNNQCVDIVTTLSEM

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=380, Percent_Identity=25, Blast_Score=104, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6324574, Length=273, Percent_Identity=24.9084249084249, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 44876; Mature: 44876

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSMLIDTTGKLQDVCSQLLMSCPKFIAVDTEFIRNCNEYYPRLSLIQIAWSKGKCVIDV
CCCCEECCCCHHHHHHHHHHHHCCHHEEECHHHHHHHHHHCCCCEEEEEEECCCCEEEEE
LADDIDLSVLESIFYNKEIVKIFHDCKQDIDALLTKFPRIPYPIFDSQIAAMFCAYYDNA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
VGYSKLVAQFLDVSLDKLTLKRSNWLMRPLSDDKIQYALDDVVYLYELYQVLYDNLISSK
CCHHHHHHHHHCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLWFLEEMSNIVKQEASYGNIYDISDFPSEVTKDEIIISWSIVEWREKLAKYFNVNRDF
HHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCE
VLKNKAIPYLAKDLVGKSDISILKKYIKKEYLLHDTTFDVFQIISNNQSIDVGGLSSVTS
EEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCC
NNNKSVLNILLILLYNICYENNISQKLVCSKGSLIRFLNGKSSYVMTGWRYEFFGCKIEK
CCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEEECCCCCEEEECCEEEECCCHHHH
FMQGKSKIIVSAQALNNQCVDIVTTLSEM
HHCCCCEEEEEHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MKSMLIDTTGKLQDVCSQLLMSCPKFIAVDTEFIRNCNEYYPRLSLIQIAWSKGKCVIDV
CCCCEECCCCHHHHHHHHHHHHCCHHEEECHHHHHHHHHHCCCCEEEEEEECCCCEEEEE
LADDIDLSVLESIFYNKEIVKIFHDCKQDIDALLTKFPRIPYPIFDSQIAAMFCAYYDNA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
VGYSKLVAQFLDVSLDKLTLKRSNWLMRPLSDDKIQYALDDVVYLYELYQVLYDNLISSK
CCHHHHHHHHHCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLWFLEEMSNIVKQEASYGNIYDISDFPSEVTKDEIIISWSIVEWREKLAKYFNVNRDF
HHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCE
VLKNKAIPYLAKDLVGKSDISILKKYIKKEYLLHDTTFDVFQIISNNQSIDVGGLSSVTS
EEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCC
NNNKSVLNILLILLYNICYENNISQKLVCSKGSLIRFLNGKSSYVMTGWRYEFFGCKIEK
CCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEEECCCCCEEEECCEEEECCCHHHH
FMQGKSKIIVSAQALNNQCVDIVTTLSEM
HHCCCCEEEEEHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]