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The map label for this gene is ubiA [H]

Identifier: 58617326

GI number: 58617326

Start: 969242

End: 970129

Strand: Reverse

Name: ubiA [H]

Synonym: ERGA_CDS_05990

Alternate gene names: 58617326

Gene position: 970129-969242 (Counterclockwise)

Preceding gene: 58617330

Following gene: 58617325

Centisome position: 64.68

GC content: 29.84

Gene sequence:

>888_bases
ATGTATATGTTATGTAAACTTAAGGATGTTCTTTCAGATTTTAAAGGATATTATTTTTTATTAAGATTACATAGTGTGTG
GATAATTTGTTTATTAGTTTTTCCTAGTTGTACAAGTATACTTTTAGTATCTAATAATCTGTTGCGTGATACTTTATATA
TGTTTCTATGTCTTGTAGGTTCATTCCTTATGAGATCTGCTGGTTGTATAATTAATGACATTTGTGATAGAAAAATAGAT
ATAGCGGTTGAACGAACTAAAAGTAGACCGTTAGCTAATGGTAGTTTGAGTGTTTTTCAAGCATTAAAAGTGTTAGCAGT
ATTGTTACTATGTGCAAGTGTTTTACTTGTGTTTACTAATATGTATACAGTAAAAATAAGCCTTGTGACTATGGTTCTCA
TAATTTTATATCCACTGGCTAAAAGGTGTTTTTCTTGGCCACAATTATTATTAGGAATAGTGTTTAATAGTGGAGTATTG
ATGGGATGTACTATGGTTATTGGGCATTTAGCATTGAGTAGTGTTTTGCTTTATATTGGATGTATTTTTTGGACATTGGG
TTACGATACTATATATGCTGCACAGGATAAAAAATATGATATGCAACTAGGTTTAAAATCTACTGCTATAGAATTTGGTG
ATAATATCAGGTCATGGATTAAAAGATTGTACATTATTGTTATAACAATGTGGGTATCAGCTGGTATTATTGCTGTATTG
CATCCTATATTTTATCTCGCTATGCTTATTATAGCTGGGGTTTTCTATTATCAATATAAAAAATCAGATTTTGACAATCC
AGGAAAATGTATGTATATGTTTAAAATCAATATATATGTAGGGATGATCTTGTTCCTGGGTGCTTTGCTTGGTAGGATTA
TGAGATAA

Upstream 100 bases:

>100_bases
AGGTTATCTAATCAAAAAGTATTTTAAAGAATAATTATATATTTAATATACATGTATTTCTACTTTTGATAAATATATGT
AGTGTGTGTAGTGTTAGGAG

Downstream 100 bases:

>100_bases
TGTTTGTGAAAAATTACTTTAGTTTCTTGATTGTTGTTAAGGTATATAGGTAAATGCAAGTAGGTGGTTTTTCTAAAGCT
TATCTTAAGTCTTGCTTAGG

Product: 4-hydroxybenzoate polyprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MYMLCKLKDVLSDFKGYYFLLRLHSVWIICLLVFPSCTSILLVSNNLLRDTLYMFLCLVGSFLMRSAGCIINDICDRKID
IAVERTKSRPLANGSLSVFQALKVLAVLLLCASVLLVFTNMYTVKISLVTMVLIILYPLAKRCFSWPQLLLGIVFNSGVL
MGCTMVIGHLALSSVLLYIGCIFWTLGYDTIYAAQDKKYDMQLGLKSTAIEFGDNIRSWIKRLYIIVITMWVSAGIIAVL
HPIFYLAMLIIAGVFYYQYKKSDFDNPGKCMYMFKINIYVGMILFLGALLGRIMR

Sequences:

>Translated_295_residues
MYMLCKLKDVLSDFKGYYFLLRLHSVWIICLLVFPSCTSILLVSNNLLRDTLYMFLCLVGSFLMRSAGCIINDICDRKID
IAVERTKSRPLANGSLSVFQALKVLAVLLLCASVLLVFTNMYTVKISLVTMVLIILYPLAKRCFSWPQLLLGIVFNSGVL
MGCTMVIGHLALSSVLLYIGCIFWTLGYDTIYAAQDKKYDMQLGLKSTAIEFGDNIRSWIKRLYIIVITMWVSAGIIAVL
HPIFYLAMLIIAGVFYYQYKKSDFDNPGKCMYMFKINIYVGMILFLGALLGRIMR
>Mature_295_residues
MYMLCKLKDVLSDFKGYYFLLRLHSVWIICLLVFPSCTSILLVSNNLLRDTLYMFLCLVGSFLMRSAGCIINDICDRKID
IAVERTKSRPLANGSLSVFQALKVLAVLLLCASVLLVFTNMYTVKISLVTMVLIILYPLAKRCFSWPQLLLGIVFNSGVL
MGCTMVIGHLALSSVLLYIGCIFWTLGYDTIYAAQDKKYDMQLGLKSTAIEFGDNIRSWIKRLYIIVITMWVSAGIIAVL
HPIFYLAMLIIAGVFYYQYKKSDFDNPGKCMYMFKINIYVGMILFLGALLGRIMR

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=276, Percent_Identity=36.231884057971, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI1790473, Length=258, Percent_Identity=33.7209302325581, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17553718, Length=285, Percent_Identity=37.5438596491228, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI32565247, Length=286, Percent_Identity=36.013986013986, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17553720, Length=343, Percent_Identity=30.3206997084548, Blast_Score=134, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI32565245, Length=141, Percent_Identity=43.2624113475177, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI32565243, Length=140, Percent_Identity=42.8571428571429, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6324370, Length=273, Percent_Identity=34.4322344322344, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21355567, Length=291, Percent_Identity=37.8006872852234, Blast_Score=184, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 33488; Mature: 33488

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
8.8 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
8.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYMLCKLKDVLSDFKGYYFLLRLHSVWIICLLVFPSCTSILLVSNNLLRDTLYMFLCLVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFLMRSAGCIINDICDRKIDIAVERTKSRPLANGSLSVFQALKVLAVLLLCASVLLVFTN
HHHHHHCCHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MYTVKISLVTMVLIILYPLAKRCFSWPQLLLGIVFNSGVLMGCTMVIGHLALSSVLLYIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
CIFWTLGYDTIYAAQDKKYDMQLGLKSTAIEFGDNIRSWIKRLYIIVITMWVSAGIIAVL
HHHHHHCCHHEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HPIFYLAMLIIAGVFYYQYKKSDFDNPGKCMYMFKINIYVGMILFLGALLGRIMR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA