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The map label for this gene is ppiD [H]

Identifier: 58617080

GI number: 58617080

Start: 583094

End: 584986

Strand: Reverse

Name: ppiD [H]

Synonym: ERGA_CDS_03530

Alternate gene names: 58617080

Gene position: 584986-583094 (Counterclockwise)

Preceding gene: 58617081

Following gene: 58617078

Centisome position: 39.0

GC content: 27.95

Gene sequence:

>1893_bases
ATGAAATCTAAGGCTTTTTTTGCAAAGTTACTTCTTATAGTATTAATATGTTCTCTAATTTCTGTATCAGTAGGAGTGCC
ATTATTTTCTAATCATTTTAGTAATAAGCAATATGTAGCAAAAATTGGGCAAGAAAAATTATCAATAGAGGACTTTACAA
CTGCTTATCATGATGAATTAAGATATATACAACAACTCCTAAATCGTCCTTTAACACCTGAACAAATTGTGCAGTTTAAT
GTGAAATTTTCCGTATTAAACAGGCTTATTGAAAATAAAGTACTTACAAAATTTGCTAATTCATTGAACCTTAAAGTTGG
TGAAGAAAGTGTAATAAATTTTATAAAAAGTATAAAATATTTCCAAGATGAGAATGGAAACTTTGATAAAAAGAAGTTCA
ACGCTGGGTTATCAAATGCAGGATTAACAGAAAGACTATATATCAGTAAATTAGAATCAGCTTTTCCTATTTCCATCATG
ATGAACTGTTTATTTGGTGGACCACAAAATAATTACTTACAATATTATCCAGATTTAACAAAAAAAATCTTACAGAATCT
TCATCAATCTCGTACCGTCGATATCATTGAAATATCACCTGTAATAAACGATATTTCCATTCCTAACATGGAAGAACTTA
AAAGTCTATATGAAGAAAAAAAGAAAAACAATAGCCTGGTTTTCCCAGAAAGTCGTGATATAGAGTATGTTACTATTAAC
TATGAAAACTTTACAACTAAAGCAACAGTCTCACAAGAAGAAATAGATAGTGAAATAAAAGCTGAAGGCCTAGATGATCA
AATAGATATACTAAATTTAGTATTTAGTGCTAAATCTGATGCTGAAAATGCATTAAGTGAACTCAACAATGGTAAAACTT
TTGACAGTATAGTAACAGACCTTGCACACAGTACTTTAGATAAAATTACATTAAAAAACATTACAAAAAATACTCTTCCT
GACGATATAAGAAATCAGGTTTTTTCTTTAAAAGAAGGTGAGATAAGCCCTATACTACATAGTATGTTTGGCTGGCATAT
AATAAAAGTGACAAGTGTTCATAAAATATCAGAACATGATTTACAAGAATTAAACAAAAAAATAAGCCAAAGTATCAAGA
AGAAAAAGGCTACTGATTTATTACTCGCAGAAATTGAAATCATAAATGACAAAATTAATCATGGCACTTCGATTAAAGAA
ATAGCAAAATTATATAACTTACCAATAAAAACTATCACAACAGATATATCAGGGTATAATTTATTAGGTAAAAAAGTAAG
TATTTCAGAAGCAAACTCTAATTCAATAATACTTACTGGCTTTTCATCACAGTTAAATCAAACCTCTAACTTTATTGACA
ATGAAGATTACTTTTTTAGTGTAAGAGTCATAAAAATTGATCAAGCAAGAGAAAAAACTTTTGATGAAAGTAAGCAAGAG
TTAGTAGATGAATGGCAAAATAATTTCAAGAGCAAAAAGCTATCTAAACTTACACAAGAAATACTAATAAAACTCAAATC
AGGTATAGATATACAAAATATTGATGGTGTATTGCTAAAGCCTAATCAGGTAGTATATAGAAATAGTGTAGCTTCCATAG
ATAATCCAGGTCAGAACTACCCTAGTAATCTAGTTAATGAAATCTTTAACTTAAAAAAAGGAGAAATTAGTAAAAACTAT
TATGATGAGCAAAATCCTTCTGAACAAAAAATGCTCATAGCCGTAGTTAAAGATATAAAAAATCCAGAACAAGTAAGCAC
TGTAGACTTAAAAGCTACACAAGAAAAGTTAAGTAATAATAATACAGAATCTTTAAAAAATCAGCTTATAACATACTTAA
CTAATAAATACTCAGTAAAAATCAATAGAAAGCTTATTGAGAATATAGAATAG

Upstream 100 bases:

>100_bases
TGTTAAAGTAAAATATTGTATATAGCTATAATGAAAAGATTTGCATGAGCGTTTTTGTTTGGTATATTAAGCATGTTTTA
TACTTACATGTACATATATC

Downstream 100 bases:

>100_bases
TTTTTTATAACTCACAAATATATGATTCCATCATGATAATAATGTGAAAATCTAACTCATAAATATTAGTTTGTTATATA
ATGCATTTTTAATAATTAAT

Product: putative peptidyl-prolyl cis-trans isomerase D

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MKSKAFFAKLLLIVLICSLISVSVGVPLFSNHFSNKQYVAKIGQEKLSIEDFTTAYHDELRYIQQLLNRPLTPEQIVQFN
VKFSVLNRLIENKVLTKFANSLNLKVGEESVINFIKSIKYFQDENGNFDKKKFNAGLSNAGLTERLYISKLESAFPISIM
MNCLFGGPQNNYLQYYPDLTKKILQNLHQSRTVDIIEISPVINDISIPNMEELKSLYEEKKKNNSLVFPESRDIEYVTIN
YENFTTKATVSQEEIDSEIKAEGLDDQIDILNLVFSAKSDAENALSELNNGKTFDSIVTDLAHSTLDKITLKNITKNTLP
DDIRNQVFSLKEGEISPILHSMFGWHIIKVTSVHKISEHDLQELNKKISQSIKKKKATDLLLAEIEIINDKINHGTSIKE
IAKLYNLPIKTITTDISGYNLLGKKVSISEANSNSIILTGFSSQLNQTSNFIDNEDYFFSVRVIKIDQAREKTFDESKQE
LVDEWQNNFKSKKLSKLTQEILIKLKSGIDIQNIDGVLLKPNQVVYRNSVASIDNPGQNYPSNLVNEIFNLKKGEISKNY
YDEQNPSEQKMLIAVVKDIKNPEQVSTVDLKATQEKLSNNNTESLKNQLITYLTNKYSVKINRKLIENIE

Sequences:

>Translated_630_residues
MKSKAFFAKLLLIVLICSLISVSVGVPLFSNHFSNKQYVAKIGQEKLSIEDFTTAYHDELRYIQQLLNRPLTPEQIVQFN
VKFSVLNRLIENKVLTKFANSLNLKVGEESVINFIKSIKYFQDENGNFDKKKFNAGLSNAGLTERLYISKLESAFPISIM
MNCLFGGPQNNYLQYYPDLTKKILQNLHQSRTVDIIEISPVINDISIPNMEELKSLYEEKKKNNSLVFPESRDIEYVTIN
YENFTTKATVSQEEIDSEIKAEGLDDQIDILNLVFSAKSDAENALSELNNGKTFDSIVTDLAHSTLDKITLKNITKNTLP
DDIRNQVFSLKEGEISPILHSMFGWHIIKVTSVHKISEHDLQELNKKISQSIKKKKATDLLLAEIEIINDKINHGTSIKE
IAKLYNLPIKTITTDISGYNLLGKKVSISEANSNSIILTGFSSQLNQTSNFIDNEDYFFSVRVIKIDQAREKTFDESKQE
LVDEWQNNFKSKKLSKLTQEILIKLKSGIDIQNIDGVLLKPNQVVYRNSVASIDNPGQNYPSNLVNEIFNLKKGEISKNY
YDEQNPSEQKMLIAVVKDIKNPEQVSTVDLKATQEKLSNNNTESLKNQLITYLTNKYSVKINRKLIENIE
>Mature_630_residues
MKSKAFFAKLLLIVLICSLISVSVGVPLFSNHFSNKQYVAKIGQEKLSIEDFTTAYHDELRYIQQLLNRPLTPEQIVQFN
VKFSVLNRLIENKVLTKFANSLNLKVGEESVINFIKSIKYFQDENGNFDKKKFNAGLSNAGLTERLYISKLESAFPISIM
MNCLFGGPQNNYLQYYPDLTKKILQNLHQSRTVDIIEISPVINDISIPNMEELKSLYEEKKKNNSLVFPESRDIEYVTIN
YENFTTKATVSQEEIDSEIKAEGLDDQIDILNLVFSAKSDAENALSELNNGKTFDSIVTDLAHSTLDKITLKNITKNTLP
DDIRNQVFSLKEGEISPILHSMFGWHIIKVTSVHKISEHDLQELNKKISQSIKKKKATDLLLAEIEIINDKINHGTSIKE
IAKLYNLPIKTITTDISGYNLLGKKVSISEANSNSIILTGFSSQLNQTSNFIDNEDYFFSVRVIKIDQAREKTFDESKQE
LVDEWQNNFKSKKLSKLTQEILIKLKSGIDIQNIDGVLLKPNQVVYRNSVASIDNPGQNYPSNLVNEIFNLKKGEISKNY
YDEQNPSEQKMLIAVVKDIKNPEQVSTVDLKATQEKLSNNNTESLKNQLITYLTNKYSVKINRKLIENIE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=412, Percent_Identity=23.7864077669903, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 71752; Mature: 71752

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKAFFAKLLLIVLICSLISVSVGVPLFSNHFSNKQYVAKIGQEKLSIEDFTTAYHDEL
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHCHHHCCHHHHHHHHHHHH
RYIQQLLNRPLTPEQIVQFNVKFSVLNRLIENKVLTKFANSLNLKVGEESVINFIKSIKY
HHHHHHHCCCCCHHHHHEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FQDENGNFDKKKFNAGLSNAGLTERLYISKLESAFPISIMMNCLFGGPQNNYLQYYPDLT
HHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEECHHHH
KKILQNLHQSRTVDIIEISPVINDISIPNMEELKSLYEEKKKNNSLVFPESRDIEYVTIN
HHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCEEEEEEE
YENFTTKATVSQEEIDSEIKAEGLDDQIDILNLVFSAKSDAENALSELNNGKTFDSIVTD
CCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHH
LAHSTLDKITLKNITKNTLPDDIRNQVFSLKEGEISPILHSMFGWHIIKVTSVHKISEHD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCEEEEEEHHHHHHHHH
LQELNKKISQSIKKKKATDLLLAEIEIINDKINHGTSIKEIAKLYNLPIKTITTDISGYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHEEECCCCCE
LLGKKVSISEANSNSIILTGFSSQLNQTSNFIDNEDYFFSVRVIKIDQAREKTFDESKQE
ECCCEEEEECCCCCEEEEECCCHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHHHHH
LVDEWQNNFKSKKLSKLTQEILIKLKSGIDIQNIDGVLLKPNQVVYRNSVASIDNPGQNY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCEEEEECCCCCCCCCCCCC
PSNLVNEIFNLKKGEISKNYYDEQNPSEQKMLIAVVKDIKNPEQVSTVDLKATQEKLSNN
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHEEEHHHHHHHHHCCC
NTESLKNQLITYLTNKYSVKINRKLIENIE
CHHHHHHHHHHHHHCCEEEEECHHHHCCCC
>Mature Secondary Structure
MKSKAFFAKLLLIVLICSLISVSVGVPLFSNHFSNKQYVAKIGQEKLSIEDFTTAYHDEL
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHCHHHCCHHHHHHHHHHHH
RYIQQLLNRPLTPEQIVQFNVKFSVLNRLIENKVLTKFANSLNLKVGEESVINFIKSIKY
HHHHHHHCCCCCHHHHHEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FQDENGNFDKKKFNAGLSNAGLTERLYISKLESAFPISIMMNCLFGGPQNNYLQYYPDLT
HHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEECHHHH
KKILQNLHQSRTVDIIEISPVINDISIPNMEELKSLYEEKKKNNSLVFPESRDIEYVTIN
HHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCEEEEEEE
YENFTTKATVSQEEIDSEIKAEGLDDQIDILNLVFSAKSDAENALSELNNGKTFDSIVTD
CCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHH
LAHSTLDKITLKNITKNTLPDDIRNQVFSLKEGEISPILHSMFGWHIIKVTSVHKISEHD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCEEEEEEHHHHHHHHH
LQELNKKISQSIKKKKATDLLLAEIEIINDKINHGTSIKEIAKLYNLPIKTITTDISGYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHEEECCCCCE
LLGKKVSISEANSNSIILTGFSSQLNQTSNFIDNEDYFFSVRVIKIDQAREKTFDESKQE
ECCCEEEEECCCCCEEEEECCCHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHHHHH
LVDEWQNNFKSKKLSKLTQEILIKLKSGIDIQNIDGVLLKPNQVVYRNSVASIDNPGQNY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCEEEEECCCCCCCCCCCCC
PSNLVNEIFNLKKGEISKNYYDEQNPSEQKMLIAVVKDIKNPEQVSTVDLKATQEKLSNN
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHEEEHHHHHHHHHCCC
NTESLKNQLITYLTNKYSVKINRKLIENIE
CHHHHHHHHHHHHHCCEEEEECHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]