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The map label for this gene is trxB [H]

Identifier: 58617077

GI number: 58617077

Start: 578328

End: 579287

Strand: Reverse

Name: trxB [H]

Synonym: ERGA_CDS_03500

Alternate gene names: 58617077

Gene position: 579287-578328 (Counterclockwise)

Preceding gene: 58617078

Following gene: 58617075

Centisome position: 38.62

GC content: 35.0

Gene sequence:

>960_bases
ATGACACAAATATATAAAACTCAAGTTTTAATTTTAGGATCTGGAGCAGCAGGATGTACTGCTGCTATATATGCTGCGCG
TGCAAATTTACAACCCATATTAATTACGGGAATGTGCCCTGGAGGTCAACTCACAATTACTACAGATGTAGAAAATTTTC
CAGGATTTGCACATGCAGTACAAGGTCCAAATCTTATGGAACAAATGCAACAACAAGCTTATAACTCTGGAGCTAAAATT
ATCTCTGATGAAATTAAAGAAATACGTACAGACATGTATCCATTTGAATGTATAGGAATATTTGATGATCATTACATTGC
AAATAGTATAATTATTGCTACAGGAGCTCAAGCCAAGTGGCTAAATATAGAAAGCGAAGAAGCTTTTAAAGGTAAGGGAG
TTTCAGCATGTGCTACATGTGATGGAGTTTTTTTTAGCGGAAGTGATGTTGCTGTAGTAGGAGGAGGTAATACTGCTGTA
GAAGAAGCACTATATTTAACCAGACATGCAACAAAAGTATTCTTAATACACAGACGTGATAAATTACGTGCTGAACCCAT
ACTACAAAAACGGTTATTCAGTAACGACAAAATACAAGTTATATGGAACAGTAGTGTTAAAGAAATACTAGGTAATAAAG
AAAATGGCACTGTTGAAAAAGTAATATTAGAATCTACAAACACTGGAAATACTACTACTCTTCCAGTAAAAGGAGTGTTT
ATTGCTATAGGACATGCTCCAAATACTAAGATTCTAAAGAAACCAGACAATACAAATATAGTAAGTCTAGATGATGAAGG
ATATATTATTACTAATCCAAATAGCACAGTAACTAGTTGTCCAGGAATTTTTGCTGCAGGTGATGTACAAGATAAAATAT
ATAGGCAGGCTGTTGTTGCAGCAGGTTCAGGGTGTATGGCAGCAATAGAAGCTGCAAAGTTTCTTTCACAACTAAAGTAG

Upstream 100 bases:

>100_bases
GATAAAGGGAGATCCAGCAATGGAAGCTTCTCAACATGGCATCGAGGACTATTTAAAATCACATATAGATAATCTTGAAA
AAAGTATTATGGACAAATAA

Downstream 100 bases:

>100_bases
TTATAACATTCTTAACTAGATGTATTATTATCACAATGTGTTACGCGTTTTTATACTAATGGCACATAGATATTACAAAA
CATCTCTGATACAATATTTA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTQIYKTQVLILGSGAAGCTAAIYAARANLQPILITGMCPGGQLTITTDVENFPGFAHAVQGPNLMEQMQQQAYNSGAKI
ISDEIKEIRTDMYPFECIGIFDDHYIANSIIIATGAQAKWLNIESEEAFKGKGVSACATCDGVFFSGSDVAVVGGGNTAV
EEALYLTRHATKVFLIHRRDKLRAEPILQKRLFSNDKIQVIWNSSVKEILGNKENGTVEKVILESTNTGNTTTLPVKGVF
IAIGHAPNTKILKKPDNTNIVSLDDEGYIITNPNSTVTSCPGIFAAGDVQDKIYRQAVVAAGSGCMAAIEAAKFLSQLK

Sequences:

>Translated_319_residues
MTQIYKTQVLILGSGAAGCTAAIYAARANLQPILITGMCPGGQLTITTDVENFPGFAHAVQGPNLMEQMQQQAYNSGAKI
ISDEIKEIRTDMYPFECIGIFDDHYIANSIIIATGAQAKWLNIESEEAFKGKGVSACATCDGVFFSGSDVAVVGGGNTAV
EEALYLTRHATKVFLIHRRDKLRAEPILQKRLFSNDKIQVIWNSSVKEILGNKENGTVEKVILESTNTGNTTTLPVKGVF
IAIGHAPNTKILKKPDNTNIVSLDDEGYIITNPNSTVTSCPGIFAAGDVQDKIYRQAVVAAGSGCMAAIEAAKFLSQLK
>Mature_318_residues
TQIYKTQVLILGSGAAGCTAAIYAARANLQPILITGMCPGGQLTITTDVENFPGFAHAVQGPNLMEQMQQQAYNSGAKII
SDEIKEIRTDMYPFECIGIFDDHYIANSIIIATGAQAKWLNIESEEAFKGKGVSACATCDGVFFSGSDVAVVGGGNTAVE
EALYLTRHATKVFLIHRRDKLRAEPILQKRLFSNDKIQVIWNSSVKEILGNKENGTVEKVILESTNTGNTTTLPVKGVFI
AIGHAPNTKILKKPDNTNIVSLDDEGYIITNPNSTVTSCPGIFAAGDVQDKIYRQAVVAAGSGCMAAIEAAKFLSQLK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=325, Percent_Identity=50.1538461538461, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI87081763, Length=320, Percent_Identity=31.5625, Blast_Score=121, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6320560, Length=322, Percent_Identity=44.4099378881988, Blast_Score=273, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6321898, Length=326, Percent_Identity=42.0245398773006, Blast_Score=256, Evalue=4e-69,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34208; Mature: 34076

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQIYKTQVLILGSGAAGCTAAIYAARANLQPILITGMCPGGQLTITTDVENFPGFAHAV
CCEEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHC
QGPNLMEQMQQQAYNSGAKIISDEIKEIRTDMYPFECIGIFDDHYIANSIIIATGAQAKW
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEEECEEEEEECCCEEE
LNIESEEAFKGKGVSACATCDGVFFSGSDVAVVGGGNTAVEEALYLTRHATKVFLIHRRD
EECCCCHHHCCCCCEEEEEECCEEECCCCEEEEECCCHHHHHHHHHHHCCEEEEEEEECC
KLRAEPILQKRLFSNDKIQVIWNSSVKEILGNKENGTVEKVILESTNTGNTTTLPVKGVF
CCCCCHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEEEEE
IAIGHAPNTKILKKPDNTNIVSLDDEGYIITNPNSTVTSCPGIFAAGDVQDKIYRQAVVA
EEEECCCCCCEEECCCCCCEEEECCCCEEEECCCCCEECCCCCEEECCHHHHHHHHHHHH
AGSGCMAAIEAAKFLSQLK
CCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQIYKTQVLILGSGAAGCTAAIYAARANLQPILITGMCPGGQLTITTDVENFPGFAHAV
CEEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHC
QGPNLMEQMQQQAYNSGAKIISDEIKEIRTDMYPFECIGIFDDHYIANSIIIATGAQAKW
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEEECEEEEEECCCEEE
LNIESEEAFKGKGVSACATCDGVFFSGSDVAVVGGGNTAVEEALYLTRHATKVFLIHRRD
EECCCCHHHCCCCCEEEEEECCEEECCCCEEEEECCCHHHHHHHHHHHCCEEEEEEEECC
KLRAEPILQKRLFSNDKIQVIWNSSVKEILGNKENGTVEKVILESTNTGNTTTLPVKGVF
CCCCCHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEEEEE
IAIGHAPNTKILKKPDNTNIVSLDDEGYIITNPNSTVTSCPGIFAAGDVQDKIYRQAVVA
EEEECCCCCCEEECCCCCCEEEECCCCEEEECCCCCEECCCCCEEECCHHHHHHHHHHHH
AGSGCMAAIEAAKFLSQLK
CCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]