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The map label for this gene is argD [H]

Identifier: 58616935

GI number: 58616935

Start: 338235

End: 339410

Strand: Reverse

Name: argD [H]

Synonym: ERGA_CDS_02080

Alternate gene names: 58616935

Gene position: 339410-338235 (Counterclockwise)

Preceding gene: 58616939

Following gene: 58616934

Centisome position: 22.63

GC content: 34.86

Gene sequence:

>1176_bases
ATGCATAATTCACCAATCTTACAGGTTTATGATCCTTCAACTGTTACTTTTTCACATGGGAAGGGAGTATACTTATATGG
TCATGATGGGAAAAAATATATAGATTTTCACTCAGGAATTGCAACAAGTTCTTTAGGGCATGCACATCCTGTATTAGTTG
AAACCTTAAAAAGACAAGGTGAAAAATTATGGCACCTATCAAATTTACACACAATACCTGAAGCTATAAAGCTAGCACAA
AAACTAGTAGATATCAGCTTTGCAGATAAGGTTTTTTTCAATAACTCAGGAGCCGAATCTGTAGAGTGTGCACTAAAAAT
AGCACGATCATACCAATGTGGTAAAGGTAATACTCAACGTTACAGGTTTATAACACTAAGGCGTTCTTTTCATGGTAGAA
CTTATACTGCATGTTCAGCAAATGAGCCAAATAATTTCTCTCCTCTGTTAAAACCATACGTTGAATGGTTTGATAGTGCA
GAACCTGATATCAACTCTATAAAAAATGCACTGACTGAGAATACAGGTGCAATATTAATAGAACCCATTCAGGGAGAAGG
AGGAATTAATGTACTTGATGCCTCATTTATTAAAGAGCTACGCACAATCTGTGATCAAAATGATATATTATTAATTTTTG
ATTGTGTACAATGTGGAGCTGGAAGGACAGGAAAGTTTTTTGCCCACGAACATATCAATGTAACCCCTGACATATGTACT
CTTGCAAAAGGATTAGGTGGCGGTTTCCCAGTATCAGCATGTTTATCAACTAATAATGCTTCTCAATTTATGACACCTGG
AATGCATGGATCTACATTTGGAGGAAACCCTCTAGCTACTACTATTGCAGGAGCTGTTGTTGATGAAATCTTAAAGGATG
GATTCTTAGAGAATGTCACGAAAAATGGTCAGTACTTACATAAAAAGCTAGAAGACTTATCTAACAAATTCTCGGTAATT
GAACAAATAAAAGGAAAAGGGCTACTAATCGGGGTAAAAGTTAATACCGATAGTAGAGCATTAATGAAAGATTTATTAAA
TTATGGGTTATTACTCAGTACCGCATCTGGCAATGTTTTAAGAATAATGCCACCTTTAATAATAACCCAACAAGAAATTG
ATGAAGGTATTAGCCTTTTGGAAAGCTATCTACAAGAAAATAAGAATAAATTGTAG

Upstream 100 bases:

>100_bases
TTTCTTAGTTGACATATAACAATATTATGCTAAATTACGCGTTAGCTGATATTTTAGTACACTATCTCACAGGTTTCAAA
AATTTTGAGGAGTAGTTTTT

Downstream 100 bases:

>100_bases
ACAGCAAGTAATTGGTTTATACTTTACTAAGTTTGCTTGAAAAAGTTCTTATTATTTATCTGAAAGTTATGGGGGTAATA
TTATGTTAACTTCAGGTTTT

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MHNSPILQVYDPSTVTFSHGKGVYLYGHDGKKYIDFHSGIATSSLGHAHPVLVETLKRQGEKLWHLSNLHTIPEAIKLAQ
KLVDISFADKVFFNNSGAESVECALKIARSYQCGKGNTQRYRFITLRRSFHGRTYTACSANEPNNFSPLLKPYVEWFDSA
EPDINSIKNALTENTGAILIEPIQGEGGINVLDASFIKELRTICDQNDILLIFDCVQCGAGRTGKFFAHEHINVTPDICT
LAKGLGGGFPVSACLSTNNASQFMTPGMHGSTFGGNPLATTIAGAVVDEILKDGFLENVTKNGQYLHKKLEDLSNKFSVI
EQIKGKGLLIGVKVNTDSRALMKDLLNYGLLLSTASGNVLRIMPPLIITQQEIDEGISLLESYLQENKNKL

Sequences:

>Translated_391_residues
MHNSPILQVYDPSTVTFSHGKGVYLYGHDGKKYIDFHSGIATSSLGHAHPVLVETLKRQGEKLWHLSNLHTIPEAIKLAQ
KLVDISFADKVFFNNSGAESVECALKIARSYQCGKGNTQRYRFITLRRSFHGRTYTACSANEPNNFSPLLKPYVEWFDSA
EPDINSIKNALTENTGAILIEPIQGEGGINVLDASFIKELRTICDQNDILLIFDCVQCGAGRTGKFFAHEHINVTPDICT
LAKGLGGGFPVSACLSTNNASQFMTPGMHGSTFGGNPLATTIAGAVVDEILKDGFLENVTKNGQYLHKKLEDLSNKFSVI
EQIKGKGLLIGVKVNTDSRALMKDLLNYGLLLSTASGNVLRIMPPLIITQQEIDEGISLLESYLQENKNKL
>Mature_391_residues
MHNSPILQVYDPSTVTFSHGKGVYLYGHDGKKYIDFHSGIATSSLGHAHPVLVETLKRQGEKLWHLSNLHTIPEAIKLAQ
KLVDISFADKVFFNNSGAESVECALKIARSYQCGKGNTQRYRFITLRRSFHGRTYTACSANEPNNFSPLLKPYVEWFDSA
EPDINSIKNALTENTGAILIEPIQGEGGINVLDASFIKELRTICDQNDILLIFDCVQCGAGRTGKFFAHEHINVTPDICT
LAKGLGGGFPVSACLSTNNASQFMTPGMHGSTFGGNPLATTIAGAVVDEILKDGFLENVTKNGQYLHKKLEDLSNKFSVI
EQIKGKGLLIGVKVNTDSRALMKDLLNYGLLLSTASGNVLRIMPPLIITQQEIDEGISLLESYLQENKNKL

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=384, Percent_Identity=33.8541666666667, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI13994255, Length=445, Percent_Identity=28.0898876404494, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI284507298, Length=296, Percent_Identity=33.7837837837838, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI37574042, Length=431, Percent_Identity=26.4501160092807, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI24119277, Length=424, Percent_Identity=24.2924528301887, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI226442709, Length=385, Percent_Identity=27.012987012987, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI226442705, Length=431, Percent_Identity=25.5220417633411, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI188536080, Length=411, Percent_Identity=24.0875912408759, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI38679950, Length=411, Percent_Identity=24.0875912408759, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI38679946, Length=411, Percent_Identity=24.0875912408759, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI1789759, Length=380, Percent_Identity=40.5263157894737, Blast_Score=305, Evalue=4e-84,
Organism=Escherichia coli, GI1788044, Length=380, Percent_Identity=39.2105263157895, Blast_Score=297, Evalue=7e-82,
Organism=Escherichia coli, GI145693181, Length=384, Percent_Identity=32.5520833333333, Blast_Score=187, Evalue=9e-49,
Organism=Escherichia coli, GI1789016, Length=394, Percent_Identity=31.9796954314721, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1787560, Length=391, Percent_Identity=33.7595907928389, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1786991, Length=398, Percent_Identity=31.1557788944724, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786349, Length=314, Percent_Identity=26.4331210191083, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI25144271, Length=382, Percent_Identity=32.9842931937173, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI32564660, Length=441, Percent_Identity=29.7052154195011, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI25144274, Length=377, Percent_Identity=29.4429708222812, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=430, Percent_Identity=27.906976744186, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17541228, Length=218, Percent_Identity=30.2752293577982, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=390, Percent_Identity=35.1282051282051, Blast_Score=239, Evalue=4e-64,
Organism=Saccharomyces cerevisiae, GI6323470, Length=398, Percent_Identity=32.4120603015075, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324386, Length=421, Percent_Identity=27.0783847980998, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321456, Length=361, Percent_Identity=27.1468144044321, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21357415, Length=381, Percent_Identity=34.1207349081365, Blast_Score=207, Evalue=9e-54,
Organism=Drosophila melanogaster, GI28574759, Length=441, Percent_Identity=30.1587301587302, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI161085790, Length=445, Percent_Identity=29.6629213483146, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI21356575, Length=411, Percent_Identity=26.5206812652068, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281366494, Length=410, Percent_Identity=26.8292682926829, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24667139, Length=410, Percent_Identity=26.8292682926829, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24667143, Length=410, Percent_Identity=26.8292682926829, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42846; Mature: 42846

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNSPILQVYDPSTVTFSHGKGVYLYGHDGKKYIDFHSGIATSSLGHAHPVLVETLKRQG
CCCCCEEEEECCCEEEEECCCEEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCC
EKLWHLSNLHTIPEAIKLAQKLVDISFADKVFFNNSGAESVECALKIARSYQCGKGNTQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCCCCE
YRFITLRRSFHGRTYTACSANEPNNFSPLLKPYVEWFDSAEPDINSIKNALTENTGAILI
EEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEE
EPIQGEGGINVLDASFIKELRTICDQNDILLIFDCVQCGAGRTGKFFAHEHINVTPDICT
EEECCCCCCEEECHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCCCEEEECCCCCCHHHHH
LAKGLGGGFPVSACLSTNNASQFMTPGMHGSTFGGNPLATTIAGAVVDEILKDGFLENVT
HHHHCCCCCCHHHEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KNGQYLHKKLEDLSNKFSVIEQIKGKGLLIGVKVNTDSRALMKDLLNYGLLLSTASGNVL
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHCCEEEEECCCCEE
RIMPPLIITQQEIDEGISLLESYLQENKNKL
EECCCHHEEHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHNSPILQVYDPSTVTFSHGKGVYLYGHDGKKYIDFHSGIATSSLGHAHPVLVETLKRQG
CCCCCEEEEECCCEEEEECCCEEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCC
EKLWHLSNLHTIPEAIKLAQKLVDISFADKVFFNNSGAESVECALKIARSYQCGKGNTQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCCCCE
YRFITLRRSFHGRTYTACSANEPNNFSPLLKPYVEWFDSAEPDINSIKNALTENTGAILI
EEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEE
EPIQGEGGINVLDASFIKELRTICDQNDILLIFDCVQCGAGRTGKFFAHEHINVTPDICT
EEECCCCCCEEECHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCCCEEEECCCCCCHHHHH
LAKGLGGGFPVSACLSTNNASQFMTPGMHGSTFGGNPLATTIAGAVVDEILKDGFLENVT
HHHHCCCCCCHHHEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KNGQYLHKKLEDLSNKFSVIEQIKGKGLLIGVKVNTDSRALMKDLLNYGLLLSTASGNVL
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHCCEEEEECCCCEE
RIMPPLIITQQEIDEGISLLESYLQENKNKL
EECCCHHEEHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]