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The map label for this gene is rnhB

Identifier: 58616897

GI number: 58616897

Start: 276941

End: 277603

Strand: Reverse

Name: rnhB

Synonym: ERGA_CDS_01700

Alternate gene names: 58616897

Gene position: 277603-276941 (Counterclockwise)

Preceding gene: 58616899

Following gene: 58616880

Centisome position: 18.51

GC content: 29.56

Gene sequence:

>663_bases
ATGCATAATTACTTAGATAATATTATGCCAGATTTTTCTATAGAAAATGAAATATTAAAATTAAAAAATAATAAAGAGTG
TATAATTGTGGGAGTTGACGAAGTAGGATATGGTTCATTAGCTGGTCCTGTAGTATCAGCAGCAGTTTTTTTCCCAAACT
ATAATAATGAGACAACACAAGATATTAACGATTCAAAAAAACTAACACCAAAAACACGACAAAAAATCTATAACAAAATT
ATTACAAGAGTAAAATGGAGTATAGGATTTGCACATATATTTGAAATAGATGAGTATAACATATTAAATGCTACACATAT
TGCAATGAAACGAGCACTTACAGGTCTAAATGCTCACATAGATATAGATTACGTCATAATAGATGGCAACAAAATACCAA
ACATACCATGGAATGCACAAGCAATAATAGGAGGTGATACTATCAGTACATCAATTGCCGCAGCATCTATAATAGCAAAA
GTTACACGAGATAGACTTATGGAAACACTTCATATACAGTACCCACAATATAATTGGAACAAAAACAAAGGGTACGGTAC
TAAAGACCATATAACATCTCTATACAAATATGGAAAAACTATACATCACAGAAATACATTTACTCCAATATCAAAAATTA
GTTATATGTTCAAAAACTCATAA

Upstream 100 bases:

>100_bases
GATAACAATATATGTAGGCATACATATATCACTTGATATTATTTGATCAATGATATTACATTATATAATGATGTTTAGCC
TTACAAAGATATGCATATAG

Downstream 100 bases:

>100_bases
TTTTATACAAAACTAACTAAACACAATTGAAATTTTAGAAATACATACCATTAAATGACTTATTTCTTACTACAATAATC
AATATAATTAAGGTTATATC

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MHNYLDNIMPDFSIENEILKLKNNKECIIVGVDEVGYGSLAGPVVSAAVFFPNYNNETTQDINDSKKLTPKTRQKIYNKI
ITRVKWSIGFAHIFEIDEYNILNATHIAMKRALTGLNAHIDIDYVIIDGNKIPNIPWNAQAIIGGDTISTSIAAASIIAK
VTRDRLMETLHIQYPQYNWNKNKGYGTKDHITSLYKYGKTIHHRNTFTPISKISYMFKNS

Sequences:

>Translated_220_residues
MHNYLDNIMPDFSIENEILKLKNNKECIIVGVDEVGYGSLAGPVVSAAVFFPNYNNETTQDINDSKKLTPKTRQKIYNKI
ITRVKWSIGFAHIFEIDEYNILNATHIAMKRALTGLNAHIDIDYVIIDGNKIPNIPWNAQAIIGGDTISTSIAAASIIAK
VTRDRLMETLHIQYPQYNWNKNKGYGTKDHITSLYKYGKTIHHRNTFTPISKISYMFKNS
>Mature_220_residues
MHNYLDNIMPDFSIENEILKLKNNKECIIVGVDEVGYGSLAGPVVSAAVFFPNYNNETTQDINDSKKLTPKTRQKIYNKI
ITRVKWSIGFAHIFEIDEYNILNATHIAMKRALTGLNAHIDIDYVIIDGNKIPNIPWNAQAIIGGDTISTSIAAASIIAK
VTRDRLMETLHIQYPQYNWNKNKGYGTKDHITSLYKYGKTIHHRNTFTPISKISYMFKNS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=186, Percent_Identity=46.7741935483871, Blast_Score=171, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_EHRRG (Q5FFD4)

Other databases:

- EMBL:   CR925677
- RefSeq:   YP_196096.1
- ProteinModelPortal:   Q5FFD4
- SMR:   Q5FFD4
- STRING:   Q5FFD4
- GeneID:   3268147
- GenomeReviews:   CR925677_GR
- KEGG:   erg:ERGA_CDS_01700
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK00015
- BioCyc:   ERUM302409:ERGA_CDS_01700-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 25009; Mature: 25009

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNYLDNIMPDFSIENEILKLKNNKECIIVGVDEVGYGSLAGPVVSAAVFFPNYNNETTQ
CCCCHHHHCCCCCCCCHHEEECCCCCEEEEECCCCCCCCHHHHHHEEEEECCCCCCCCCC
DINDSKKLTPKTRQKIYNKIITRVKWSIGFAHIFEIDEYNILNATHIAMKRALTGLNAHI
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEE
DIDYVIIDGNKIPNIPWNAQAIIGGDTISTSIAAASIIAKVTRDRLMETLHIQYPQYNWN
EEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
KNKGYGTKDHITSLYKYGKTIHHRNTFTPISKISYMFKNS
CCCCCCCHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MHNYLDNIMPDFSIENEILKLKNNKECIIVGVDEVGYGSLAGPVVSAAVFFPNYNNETTQ
CCCCHHHHCCCCCCCCHHEEECCCCCEEEEECCCCCCCCHHHHHHEEEEECCCCCCCCCC
DINDSKKLTPKTRQKIYNKIITRVKWSIGFAHIFEIDEYNILNATHIAMKRALTGLNAHI
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEE
DIDYVIIDGNKIPNIPWNAQAIIGGDTISTSIAAASIIAKVTRDRLMETLHIQYPQYNWN
EEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
KNKGYGTKDHITSLYKYGKTIHHRNTFTPISKISYMFKNS
CCCCCCCHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA