Definition Ehrlichia ruminantium str. Gardel, complete genome.
Accession NC_006831
Length 1,499,920

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The map label for this gene is sucC

Identifier: 58616871

GI number: 58616871

Start: 240366

End: 241526

Strand: Reverse

Name: sucC

Synonym: ERGA_CDS_01440

Alternate gene names: 58616871

Gene position: 241526-240366 (Counterclockwise)

Preceding gene: 161986612

Following gene: 58616870

Centisome position: 16.1

GC content: 31.44

Gene sequence:

>1161_bases
ATGAATATTCATGAATATCAAGCAAAACAAATATTAAAAAGGTTTGGTATAAGTGTTCCAGAAGGAGTTATAGTACACTC
ATTAAATGAAGTTAATGATGCAATAAATAAGATCAACTCAAAGGTTATTGTAGTCAAAGCACAAATCCATGCAGGAGGTA
GAGGAAAAGCAGGAGGAGTTATAGTTTCACGTACATTAGATGAAGCAAAAACTGCAATAAAAAATATGTTGGGGTCAACT
CTAGTCACACATCAAACCTCAAAAGATGGACAAAAAGTAAGAAAAGTATATTTAGAAGAAGGATGTGATATAAAAAAAGA
ATATTACATCAGTGCTATTGTTAACCGTAAACATGGGCAAATTAGTATTATATTTTCAACAGAAGGTGGTGTTGATATAG
AAGAAGTAGCTGCAAACTCTCCAGAAAAGGTTGTTACATGTAATATTGATCCAATATTTGGGTTTCAAGGATTTCATGGA
CGTAATTTATGTTTTGATAGCAATTTAAGTGTAGATCAGACACGTAAAATTACTTCTATAGCTAAAAAAATATACAAAAC
AATGCTGGAAACAGATGCAAGTCAAATAGAAATTAATCCATTAATAGAAACATCATCTGGAGATTTTATTGCACTCGATG
CAAAGATGAATTTTGATGATAATGCAATATATCGTCATCCTGAAATTTTAGAGTTGCGAGATTATGATGAAGAAATTCCA
GAAGAAATAGAAGCTTCAAAACATGGCTTAAGTTATATTAAGATGGATGGTAATATTGGATGTATGGTTAATGGAGCAGG
ACTTGCTATGGCTACCATGGACATTATCAAATATTATGGAGCTGAACCTGCAAATTTTCTAGATGTAGGTGGTGGAGCAA
GTCAACAAACCGTAACTGAAGCATTTAAAATTATCTTATCAGACAATGTTGATGGGATATTAGTTAATATATTTGGTGGA
ATAATGCGTTGTGATATAATTGCTAATGGTATTATTGCTGCCATACAAGAAATAGGTATTAACGTTCCACTTGTTGTAAG
GTTATCAGGAACAAACTTTGAGCTTGGTAAAAAATTACTTGATAATTCCAAGTTAAATATCATAACAGCACATGATTTAA
GTGAAGCAGCATATGATATAGTTAATATAGTTAAGAAATAG

Upstream 100 bases:

>100_bases
CACTGAAAATAATGTGTGATAACAACCACTCTATCGTTTGTTATAATTCCTCTGTGAAGTATATGTTAAAATTAATAATT
ATGACAGGAAGGTATACTGT

Downstream 100 bases:

>100_bases
AGGCAGCATGTCCATTTTAGTAAATAGTAATACAAAAGTTATCTGCCAGGGGTTTACTGGTGCTCATGGTACATTTCATT
CAGAACAAGCTATTGCTTAT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNIHEYQAKQILKRFGISVPEGVIVHSLNEVNDAINKINSKVIVVKAQIHAGGRGKAGGVIVSRTLDEAKTAIKNMLGST
LVTHQTSKDGQKVRKVYLEEGCDIKKEYYISAIVNRKHGQISIIFSTEGGVDIEEVAANSPEKVVTCNIDPIFGFQGFHG
RNLCFDSNLSVDQTRKITSIAKKIYKTMLETDASQIEINPLIETSSGDFIALDAKMNFDDNAIYRHPEILELRDYDEEIP
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASQQTVTEAFKIILSDNVDGILVNIFGG
IMRCDIIANGIIAAIQEIGINVPLVVRLSGTNFELGKKLLDNSKLNIITAHDLSEAAYDIVNIVKK

Sequences:

>Translated_386_residues
MNIHEYQAKQILKRFGISVPEGVIVHSLNEVNDAINKINSKVIVVKAQIHAGGRGKAGGVIVSRTLDEAKTAIKNMLGST
LVTHQTSKDGQKVRKVYLEEGCDIKKEYYISAIVNRKHGQISIIFSTEGGVDIEEVAANSPEKVVTCNIDPIFGFQGFHG
RNLCFDSNLSVDQTRKITSIAKKIYKTMLETDASQIEINPLIETSSGDFIALDAKMNFDDNAIYRHPEILELRDYDEEIP
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASQQTVTEAFKIILSDNVDGILVNIFGG
IMRCDIIANGIIAAIQEIGINVPLVVRLSGTNFELGKKLLDNSKLNIITAHDLSEAAYDIVNIVKK
>Mature_386_residues
MNIHEYQAKQILKRFGISVPEGVIVHSLNEVNDAINKINSKVIVVKAQIHAGGRGKAGGVIVSRTLDEAKTAIKNMLGST
LVTHQTSKDGQKVRKVYLEEGCDIKKEYYISAIVNRKHGQISIIFSTEGGVDIEEVAANSPEKVVTCNIDPIFGFQGFHG
RNLCFDSNLSVDQTRKITSIAKKIYKTMLETDASQIEINPLIETSSGDFIALDAKMNFDDNAIYRHPEILELRDYDEEIP
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASQQTVTEAFKIILSDNVDGILVNIFGG
IMRCDIIANGIIAAIQEIGINVPLVVRLSGTNFELGKKLLDNSKLNIITAHDLSEAAYDIVNIVKK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=43.7340153452685, Blast_Score=317, Evalue=1e-86,
Organism=Homo sapiens, GI157779135, Length=387, Percent_Identity=44.4444444444444, Blast_Score=309, Evalue=3e-84,
Organism=Homo sapiens, GI294862256, Length=366, Percent_Identity=44.5355191256831, Blast_Score=292, Evalue=4e-79,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=50, Blast_Score=373, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17539378, Length=400, Percent_Identity=43.75, Blast_Score=329, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI17567829, Length=392, Percent_Identity=42.8571428571429, Blast_Score=305, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=39.8989898989899, Blast_Score=306, Evalue=3e-84,
Organism=Drosophila melanogaster, GI21356231, Length=401, Percent_Identity=43.142144638404, Blast_Score=310, Evalue=2e-84,
Organism=Drosophila melanogaster, GI161078106, Length=385, Percent_Identity=43.8961038961039, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24645208, Length=385, Percent_Identity=43.8961038961039, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI281361397, Length=386, Percent_Identity=44.300518134715, Blast_Score=306, Evalue=2e-83,
Organism=Drosophila melanogaster, GI281361395, Length=386, Percent_Identity=44.300518134715, Blast_Score=306, Evalue=2e-83,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_EHRRG (Q5FH54)

Other databases:

- EMBL:   CR925677
- RefSeq:   YP_196070.1
- HSSP:   P0A836
- ProteinModelPortal:   Q5FH54
- SMR:   Q5FH54
- STRING:   Q5FH54
- GeneID:   3268791
- GenomeReviews:   CR925677_GR
- KEGG:   erg:ERGA_CDS_01440
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- ProtClustDB:   PRK00696
- BioCyc:   ERUM302409:ERGA_CDS_01440-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42160; Mature: 42160

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNIHEYQAKQILKRFGISVPEGVIVHSLNEVNDAINKINSKVIVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
IVSRTLDEAKTAIKNMLGSTLVTHQTSKDGQKVRKVYLEEGCDIKKEYYISAIVNRKHGQ
EEECCHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHCCCCCCHHHEEEEEEECCCCE
ISIIFSTEGGVDIEEVAANSPEKVVTCNIDPIFGFQGFHGRNLCFDSNLSVDQTRKITSI
EEEEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCHHHHHHHHHH
AKKIYKTMLETDASQIEINPLIETSSGDFIALDAKMNFDDNAIYRHPEILELRDYDEEIP
HHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEEEECCCCCCEECCCCEEEECCCCHHHH
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASQQTVTE
HHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILSDNVDGILVNIFGGIMRCDIIANGIIAAIQEIGINVPLVVRLSGTNFELGKKLL
HHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
DNSKLNIITAHDLSEAAYDIVNIVKK
CCCCEEEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKQILKRFGISVPEGVIVHSLNEVNDAINKINSKVIVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
IVSRTLDEAKTAIKNMLGSTLVTHQTSKDGQKVRKVYLEEGCDIKKEYYISAIVNRKHGQ
EEECCHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHCCCCCCHHHEEEEEEECCCCE
ISIIFSTEGGVDIEEVAANSPEKVVTCNIDPIFGFQGFHGRNLCFDSNLSVDQTRKITSI
EEEEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCHHHHHHHHHH
AKKIYKTMLETDASQIEINPLIETSSGDFIALDAKMNFDDNAIYRHPEILELRDYDEEIP
HHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEEEECCCCCCEECCCCEEEECCCCHHHH
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASQQTVTE
HHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILSDNVDGILVNIFGGIMRCDIIANGIIAAIQEIGINVPLVVRLSGTNFELGKKLL
HHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
DNSKLNIITAHDLSEAAYDIVNIVKK
CCCCEEEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA