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The map label for this gene is sucD [H]

Identifier: 58616870

GI number: 58616870

Start: 239471

End: 240358

Strand: Reverse

Name: sucD [H]

Synonym: ERGA_CDS_01430

Alternate gene names: 58616870

Gene position: 240358-239471 (Counterclockwise)

Preceding gene: 58616871

Following gene: 58616868

Centisome position: 16.02

GC content: 37.27

Gene sequence:

>888_bases
ATGTCCATTTTAGTAAATAGTAATACAAAAGTTATCTGCCAGGGGTTTACTGGTGCTCATGGTACATTTCATTCAGAACA
AGCTATTGCTTATGGAACAAAAATGGTTGGTGGAGTAACTCCTGGTAAAGGTGGGACATATCACCTTAACTTACCAGTTT
TTAACACTGTGAAACAGGCAAAATTACAAGTCGGAGCTAATGCTACAGTAATTTATGTCCCTGCTCCGTACGCAGCTGAT
GCTATATTAGAAGCAATTGAGGCTGAAATTGAACTTATTATTTGTATTACAGAAGGTATCCCTACTTTAGATATGGTACA
AGTAAAGCGTGCTTTATGCAATTCCAAGAGTATCTTAATAGGACCTAACTGCCCAGGAATTATTACTCCAGAAGAGTGTA
AAATTGGTATTATGCCTGGATATATACACAAACGTGGTCATATAGGTGTAATTTCACGATCTGGTACATTAACATATGAA
GCAGTAGCACAAACTACAGAAGCAGGATTAGGACAATCAACATGTATTGGTATTGGTGGAGATCCTATACACGGTATGTC
TTTTACAGACTGTTTAAAATTATTTATCAATGATCCAGATACACATGGTATCATCATGATTGGAGAAATTGGTGGTTCAG
AAGAAGAAGAGGCAGCAGAATTTATTAAATTATCAGGAACAACTAAACCTATTGTTGGTTTTGTTGCTGGAAAAACCGCA
CCTCCTGGCAGGCGTATGGGACATGCTGGAGCAATCTCATCAGGTAGCTCAGGTAGTGCTGAAAGCAAGATACAAATCAT
GAAAAGTGCCGGTATTATCATTGCTGAAACTCCAGCAGTAATAGGTAAAACAATGTTTGAAGCCATGAGTAATATTACAA
AAAATTAA

Upstream 100 bases:

>100_bases
AAAAAATTACTTGATAATTCCAAGTTAAATATCATAACAGCACATGATTTAAGTGAAGCAGCATATGATATAGTTAATAT
AGTTAAGAAATAGAGGCAGC

Downstream 100 bases:

>100_bases
TAGTTTTTTAGTATCTATATTTAAATGTACACATAACATTATTATGTACAATAGCACTTACTAACAAATATGATGTAATT
ATTATTACCTAGTACTTATC

Product: succinyl-CoA synthetase alpha chain

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSILVNSNTKVICQGFTGAHGTFHSEQAIAYGTKMVGGVTPGKGGTYHLNLPVFNTVKQAKLQVGANATVIYVPAPYAAD
AILEAIEAEIELIICITEGIPTLDMVQVKRALCNSKSILIGPNCPGIITPEECKIGIMPGYIHKRGHIGVISRSGTLTYE
AVAQTTEAGLGQSTCIGIGGDPIHGMSFTDCLKLFINDPDTHGIIMIGEIGGSEEEEAAEFIKLSGTTKPIVGFVAGKTA
PPGRRMGHAGAISSGSSGSAESKIQIMKSAGIIIAETPAVIGKTMFEAMSNITKN

Sequences:

>Translated_295_residues
MSILVNSNTKVICQGFTGAHGTFHSEQAIAYGTKMVGGVTPGKGGTYHLNLPVFNTVKQAKLQVGANATVIYVPAPYAAD
AILEAIEAEIELIICITEGIPTLDMVQVKRALCNSKSILIGPNCPGIITPEECKIGIMPGYIHKRGHIGVISRSGTLTYE
AVAQTTEAGLGQSTCIGIGGDPIHGMSFTDCLKLFINDPDTHGIIMIGEIGGSEEEEAAEFIKLSGTTKPIVGFVAGKTA
PPGRRMGHAGAISSGSSGSAESKIQIMKSAGIIIAETPAVIGKTMFEAMSNITKN
>Mature_294_residues
SILVNSNTKVICQGFTGAHGTFHSEQAIAYGTKMVGGVTPGKGGTYHLNLPVFNTVKQAKLQVGANATVIYVPAPYAADA
ILEAIEAEIELIICITEGIPTLDMVQVKRALCNSKSILIGPNCPGIITPEECKIGIMPGYIHKRGHIGVISRSGTLTYEA
VAQTTEAGLGQSTCIGIGGDPIHGMSFTDCLKLFINDPDTHGIIMIGEIGGSEEEEAAEFIKLSGTTKPIVGFVAGKTAP
PGRRMGHAGAISSGSSGSAESKIQIMKSAGIIIAETPAVIGKTMFEAMSNITKN

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=289, Percent_Identity=64.7058823529412, Blast_Score=332, Evalue=3e-91,
Organism=Homo sapiens, GI38569421, Length=298, Percent_Identity=28.1879194630872, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI38569423, Length=298, Percent_Identity=28.1879194630872, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1786949, Length=294, Percent_Identity=64.6258503401361, Blast_Score=377, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17550194, Length=292, Percent_Identity=58.9041095890411, Blast_Score=337, Evalue=4e-93,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=59.5890410958904, Blast_Score=333, Evalue=7e-92,
Organism=Caenorhabditis elegans, GI17557344, Length=264, Percent_Identity=25.7575757575758, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17551266, Length=225, Percent_Identity=27.1111111111111, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6324716, Length=299, Percent_Identity=50.1672240802676, Blast_Score=280, Evalue=2e-76,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=57.8767123287671, Blast_Score=350, Evalue=6e-97,
Organism=Drosophila melanogaster, GI28574296, Length=295, Percent_Identity=61.3559322033898, Blast_Score=332, Evalue=1e-91,
Organism=Drosophila melanogaster, GI281363477, Length=230, Percent_Identity=27.8260869565217, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI281363475, Length=230, Percent_Identity=27.8260869565217, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI281363473, Length=230, Percent_Identity=27.8260869565217, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30671; Mature: 30540

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVNSNTKVICQGFTGAHGTFHSEQAIAYGTKMVGGVTPGKGGTYHLNLPVFNTVKQA
CEEEEECCCEEEEECCCCCCCCCCCCCHHHHCCHHHCCCCCCCCCEEEEECCHHHHHHHH
KLQVGANATVIYVPAPYAADAILEAIEAEIELIICITEGIPTLDMVQVKRALCNSKSILI
HEEECCCEEEEEECCCHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEE
GPNCPGIITPEECKIGIMPGYIHKRGHIGVISRSGTLTYEAVAQTTEAGLGQSTCIGIGG
CCCCCCCCCCCCCEEEECCCCEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIHGMSFTDCLKLFINDPDTHGIIMIGEIGGSEEEEAAEFIKLSGTTKPIVGFVAGKTA
CCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHEEEECCCCCCEEEEEECCCC
PPGRRMGHAGAISSGSSGSAESKIQIMKSAGIIIAETPAVIGKTMFEAMSNITKN
CCCCCCCCCCCCCCCCCCCCHHEEEEEECCCEEEEECCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SILVNSNTKVICQGFTGAHGTFHSEQAIAYGTKMVGGVTPGKGGTYHLNLPVFNTVKQA
EEEEECCCEEEEECCCCCCCCCCCCCHHHHCCHHHCCCCCCCCCEEEEECCHHHHHHHH
KLQVGANATVIYVPAPYAADAILEAIEAEIELIICITEGIPTLDMVQVKRALCNSKSILI
HEEECCCEEEEEECCCHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEE
GPNCPGIITPEECKIGIMPGYIHKRGHIGVISRSGTLTYEAVAQTTEAGLGQSTCIGIGG
CCCCCCCCCCCCCEEEECCCCEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIHGMSFTDCLKLFINDPDTHGIIMIGEIGGSEEEEAAEFIKLSGTTKPIVGFVAGKTA
CCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHEEEECCCCCCEEEEEECCCC
PPGRRMGHAGAISSGSSGSAESKIQIMKSAGIIIAETPAVIGKTMFEAMSNITKN
CCCCCCCCCCCCCCCCCCCCHHEEEEEECCCEEEEECCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]