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The map label for this gene is mraY

Identifier: 57650294

GI number: 57650294

Start: 1200166

End: 1201131

Strand: Direct

Name: mraY

Synonym: SACOL1195

Alternate gene names: 57650294

Gene position: 1200166-1201131 (Clockwise)

Preceding gene: 57650293

Following gene: 57650295

Centisome position: 42.72

GC content: 32.19

Gene sequence:

>966_bases
ATGATTTTTGTATATGCGTTATTAGCGCTAGTGATTACATTTGTTTTGGTACCTGTTTTAATACCTACATTAAAAAGGAT
GAAATTTGGTCAAAGTATTCGAGAAGAAGGTCCACAAAGCCATATGAAGAAGACTGGTACACCAACGATGGGTGGACTAA
CATTTCTATTAAGTATTGTGATAACGTCTTTGGTGGCTATTATATTTGTAGATCAAGCTAATCCAATCATACTGTTATTA
TTTGTGACGATTGGTTTTGGGTTAATTGGTTTTATAGATGATTATATTATTGTTGTTAAAAAGAATAACCAAGGTTTAAC
AAGTAAACAGAAGTTTTTGGCGCAAATTGGTATTGCGATTATATTCTTTGTTTTAAGTAATGTGTTTCATTTGGTGAATT
TTTCTACGAGCATACATATTCCATTTACGAATGTAGCAATCCCACTATCATTTGCATATGTTATTTTCATTGTTTTTTGG
CAAGTAGGTTTTTCTAATGCAGTAAATTTAACAGATGGTTTAGATGGATTAGCAACTGGACTGTCAATTATCGGATTTAC
AATGTATGCCATCATGAGCTTTGTGTTAGGAGAAACGGCAATTGGTATTTTCTGTATCATTATGTTGTTTGCACTTTTAG
GATTTTTACCATATAACATTAACCCTGCTAAAGTGTTTATGGGAGATACAGGTAGCTTAGCTTTAGGTGGTATATTTGCT
ACCATTTCAATCATGCTTAATCAGGAATTATCATTAATTTTTATAGGTTTAGTATTCGTAATTGAAACATTATCTGTTAT
GTTACAAGTCGCTAGCTTTAAATTGACTGGAAAGCGTATATTTAAAATGAGTCCGATTCATCATCATTTTGAATTGATAG
GATGGAGCGAATGGAAAGTAGTTACAGTATTTTGGGCTGTTGGTCTGATTTCAGGTTTAATCGGTTTATGGATTGGAGTG
CATTAA

Upstream 100 bases:

>100_bases
AGAAAAATTATAAATTTTGATTACAACTTTGTTTATTTAATTGAAAAATTGATAATATATTAGTGGTTAAAAAAGTCTGG
ATTAAGAAGAGGAGATAGTT

Downstream 100 bases:

>100_bases
GATGCTTAATTATACAGGGTTAGAAAATAAAAATGTATTAGTTGTCGGTTTGGCAAAAAGTGGTTATGAAGCAGCTAAAT
TATTAAGTAAATTAGGTGCG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIVITSLVAIIFVDQANPIILLL
FVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFW
QVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFA
TISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGV
H

Sequences:

>Translated_321_residues
MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIVITSLVAIIFVDQANPIILLL
FVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFW
QVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFA
TISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGV
H
>Mature_321_residues
MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIVITSLVAIIFVDQANPIILLL
FVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFW
QVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFA
TISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGV
H

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=331, Percent_Identity=41.9939577039275, Blast_Score=225, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_STAA1 (A7X1C2)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441762.1
- STRING:   A7X1C2
- EnsemblBacteria:   EBSTAT00000005223
- GeneID:   5559384
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1172
- eggNOG:   COG0472
- GeneTree:   EBGT00050000024846
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   SAUR418127:SAHV_1172-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 35233; Mature: 35233

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcd56b14)-; HASH(0xe4e8cbc)-; HASH(0xe114080)-; HASH(0xe1142a8)-; HASH(0xdad01b8)-; HASH(0xb5da6e4)-; HASH(0xc846324)-; HASH(0xb75d46c)-; HASH(0xc8462c4)-; HASH(0xd4ec398)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHH
ITSLVAIIFVDQANPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHH
IFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFWQVGFSNAVNLTDGLDGLATG
HHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCHHHHHHHH
TISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCHHHHHEECCCCHHH
VTVFWAVGLISGLIGLWIGVH
HHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHH
ITSLVAIIFVDQANPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHH
IFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFWQVGFSNAVNLTDGLDGLATG
HHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCHHHHHHHH
TISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCHHHHHEECCCCHHH
VTVFWAVGLISGLIGLWIGVH
HHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA