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The map label for this gene is btuC [C]

Identifier: 57238628

GI number: 57238628

Start: 1684085

End: 1685071

Strand: Direct

Name: btuC [C]

Synonym: CJE1787

Alternate gene names: 57238628

Gene position: 1684085-1685071 (Clockwise)

Preceding gene: 57238627

Following gene: 57238629

Centisome position: 94.73

GC content: 32.52

Gene sequence:

>987_bases
ATGTTGAATTTAAATACGCATTCTAAAATTTTAGTGATTATAGGGCTTTTGGTAGCTTATATAATCGCTTCTTTTATAGC
ACTTTGCTTAGGAGATGAGAATTTAAACCCAAAAGAACTTTTTTCATATATCTTTAGCCAAGATGAAATTTTAAGACAAA
TCATCATAGATGGACGCTTACCACGCATTATAATGGCGATTTTAATCGGTATGCTTTTAGCTAGTAGTGGGGCTATCACT
CAAAATGTATTTTCAAATCCTATAGCTGATCCTTATATCATAGGTATAGCTTCTGCGGCAACCTTTGGAGCGGTTTTGGC
GTATTTGTTAAAATTGAATGATTATTATTATGGAATTTTAGGTTTTGTTTGCTCTGCCTTTTTTGCCCTAGGAGTTTTTA
AAATTTCTTCTAAAGCTTCTATAGCAACTTTACTCATTATCGGCATAGCAGCTTCATCTTTTTTAGGGGCTTTTACTTCT
TTTTTCACTTATCTTATAGGCGAGGATTCTTTTAAAATAGTCGCTTGGCTTATGGGAAATATAGGCAATGCTTCTTGGTT
TCGTGTGGGAATTTTAATCTTACCTTTAATTTTTTGTTTGTTTTATTTTTACGCTCATAAAAACGAATTAAACATACTTT
TAAGCGGAGATGATGAAGCTAGAAATCTAGGGGTAAATGCTCAAAAATTAAAGATAAATTTACTCATTGTCTCATCCTTG
GCTGTATCTTTTGCGGTTGCTTTTAGCGGACTTATAGGCTTTGTTGGACTCATCATTCCTCATACTATAAGACTTTTGCT
TAAAAATTATGACAATGCCTTGGTTATCCCTTTATGTACAGCATTTGGAGGATTATTTTTACTTATTTGTGATACTTTAG
CAAGAACTCTTTTAACCCCTGTACAAATTCCGATTGGAATTTTAACTGCATTTTTTGGAGCTCCTATTTTTTTATACTTG
GCTTTAAGTGCTAGGAGATTTTTATAA

Upstream 100 bases:

>100_bases
CAAATTTTAGCAGGAATTCGCAATCTTTTCGATAAAAGATACTACACCTATCAAGACAGTATAAATGATCAATACCTAGT
TGGGAATGGCAGAAACTACT

Downstream 100 bases:

>100_bases
TGCTAAAAATACAAGATTTAAGCTTTGCTTATCACCAAAAAGATTTACTAAAAAACATTCATTTAGAACTTAAAAATCGG
GCTTTTATAGGAATTTTAGG

Product: hemin ABC transporter permease

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MLNLNTHSKILVIIGLLVAYIIASFIALCLGDENLNPKELFSYIFSQDEILRQIIIDGRLPRIIMAILIGMLLASSGAIT
QNVFSNPIADPYIIGIASAATFGAVLAYLLKLNDYYYGILGFVCSAFFALGVFKISSKASIATLLIIGIAASSFLGAFTS
FFTYLIGEDSFKIVAWLMGNIGNASWFRVGILILPLIFCLFYFYAHKNELNILLSGDDEARNLGVNAQKLKINLLIVSSL
AVSFAVAFSGLIGFVGLIIPHTIRLLLKNYDNALVIPLCTAFGGLFLLICDTLARTLLTPVQIPIGILTAFFGAPIFLYL
ALSARRFL

Sequences:

>Translated_328_residues
MLNLNTHSKILVIIGLLVAYIIASFIALCLGDENLNPKELFSYIFSQDEILRQIIIDGRLPRIIMAILIGMLLASSGAIT
QNVFSNPIADPYIIGIASAATFGAVLAYLLKLNDYYYGILGFVCSAFFALGVFKISSKASIATLLIIGIAASSFLGAFTS
FFTYLIGEDSFKIVAWLMGNIGNASWFRVGILILPLIFCLFYFYAHKNELNILLSGDDEARNLGVNAQKLKINLLIVSSL
AVSFAVAFSGLIGFVGLIIPHTIRLLLKNYDNALVIPLCTAFGGLFLLICDTLARTLLTPVQIPIGILTAFFGAPIFLYL
ALSARRFL
>Mature_328_residues
MLNLNTHSKILVIIGLLVAYIIASFIALCLGDENLNPKELFSYIFSQDEILRQIIIDGRLPRIIMAILIGMLLASSGAIT
QNVFSNPIADPYIIGIASAATFGAVLAYLLKLNDYYYGILGFVCSAFFALGVFKISSKASIATLLIIGIAASSFLGAFTS
FFTYLIGEDSFKIVAWLMGNIGNASWFRVGILILPLIFCLFYFYAHKNELNILLSGDDEARNLGVNAQKLKINLLIVSSL
AVSFAVAFSGLIGFVGLIIPHTIRLLLKNYDNALVIPLCTAFGGLFLLICDTLARTLLTPVQIPIGILTAFFGAPIFLYL
ALSARRFL

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=303, Percent_Identity=31.6831683168317, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790740, Length=275, Percent_Identity=30.5454545454545, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790741, Length=274, Percent_Identity=32.1167883211679, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786347, Length=317, Percent_Identity=29.3375394321767, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786804, Length=320, Percent_Identity=26.875, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786805, Length=282, Percent_Identity=27.6595744680851, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35687; Mature: 35687

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLNTHSKILVIIGLLVAYIIASFIALCLGDENLNPKELFSYIFSQDEILRQIIIDGRL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHCCCH
PRIIMAILIGMLLASSGAITQNVFSNPIADPYIIGIASAATFGAVLAYLLKLNDYYYGIL
HHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFVCSAFFALGVFKISSKASIATLLIIGIAASSFLGAFTSFFTYLIGEDSFKIVAWLMGN
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
IGNASWFRVGILILPLIFCLFYFYAHKNELNILLSGDDEARNLGVNAQKLKINLLIVSSL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCHHHEEEEEEHHHHH
AVSFAVAFSGLIGFVGLIIPHTIRLLLKNYDNALVIPLCTAFGGLFLLICDTLARTLLTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCH
VQIPIGILTAFFGAPIFLYLALSARRFL
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNLNTHSKILVIIGLLVAYIIASFIALCLGDENLNPKELFSYIFSQDEILRQIIIDGRL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHCCCH
PRIIMAILIGMLLASSGAITQNVFSNPIADPYIIGIASAATFGAVLAYLLKLNDYYYGIL
HHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFVCSAFFALGVFKISSKASIATLLIIGIAASSFLGAFTSFFTYLIGEDSFKIVAWLMGN
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
IGNASWFRVGILILPLIFCLFYFYAHKNELNILLSGDDEARNLGVNAQKLKINLLIVSSL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCHHHEEEEEEHHHHH
AVSFAVAFSGLIGFVGLIIPHTIRLLLKNYDNALVIPLCTAFGGLFLLICDTLARTLLTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCH
VQIPIGILTAFFGAPIFLYLALSARRFL
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]