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The map label for this gene is putA [H]

Identifier: 57238526

GI number: 57238526

Start: 1574114

End: 1577602

Strand: Reverse

Name: putA [H]

Synonym: CJE1676

Alternate gene names: 57238526

Gene position: 1577602-1574114 (Counterclockwise)

Preceding gene: 57238527

Following gene: 57238525

Centisome position: 88.74

GC content: 30.21

Gene sequence:

>3489_bases
ATGATACAAAAAGCTTTAGCCTTAGCTGAAGAATTGCAAGGACAAATAGAAGCCAATATTTCAAATTCTGAAAAAGAATT
TCATGCTAAAATGCAAAAACTTCTTAACAATCCCAAAAATAAAGTTATGCTTATAGAACTTTTAGATCGTTCTTTTAGAT
GTAAAGATAAAAATGCAAGTTTTGAGCTTATAGAATATACTTTGAGTAAATATGGCATAGCGGATTTTTTTAGCACTTTT
GAAAAATTCCTACTTTTTAGCTTTTTAAATTTTGGCAAATTTGCTCCTAATTTAAGTGTGCCTTTTTTTGTCAAACATTT
AAGAGAAGATACTAAAGCTATGGTTCTAGATGCAAACCCTAGTGTTTTAGAGCCGCATATTAATAAAAGAAAAGAGCAAG
ATAAAATTATCTTAAATGTGAATTTAATCGGCGAAGAGGTTTTAGGTGAAGCTGAGAGCAAATATCGTATGCAAAAATAT
GAAGAAGCTTTAAAATCAAGTTATATCACTTATATTTCCATAAAAATTACTACTATTTTTTCACAAATTAATATTATAGA
TTTTGATTATTCCAAAGAAGAGGTAGTAAAAAGACTAGATTATCTTTATGCTTTAGCCTTAGAAGAAGAGAAAAAACAAG
GTGTATCTAAATTTATCAATCTGGATATGGAAGAATTTAGGGATTTAGAGCTCACCGTTGCAGCTTTTATGGAAAGTGTG
GCTAAATTTGATATTAAAGCAGGGATTGTTTTGCAAGCTTATATTCCTGATTCTTATAAGTATCTTAAAAAACTTTTTGC
TTTTTCAAAAGAGAGGGTTTTAAAAGGTATGAAGCCTATTAAGATCCGTTTTGTTAAGGGTGCTAATATGGAAAGTGAAG
AAACTATTGCATCTCAAAAAGGCTGGGAGCTTCCTACTTTTTACAAAAAAATAGATACTGATAGCAATTATAATAAAATG
CTTGATTTTATTCTTGAAGGAGATAATTATAAATACATCAACATAGGAATTGCAAGTCATAATATCTTTGAGATTACTTA
TGCTTATACACGCATAAGTGAAGCGGGTGCTTTAGATTCTTTTACTTTTGAAATGCTTGAAGGTATGAGTTTACAATGTT
CTTATCAATTATCCAAAATGCATGATTTAATCCTTTATGCCCCAGTTTGTGATGAAGCACATTTTAACAATGCTATTGCT
TATCTTGTAAGACGCCTTGATGAAAATACAAGTGAAGATAATTTTATGCGTTATTTTTTCAATCTTAAAGTAGGAGATAA
AAACTGGAATATCCAAAAAGAACTTTTTTTAAAATCTTTAGAAGGTATAAAAACTCTTGATAATACTACACATCGTAAGC
AAGATAGAAATAAAGAGCAAAATATCACAAGTTCTTACGAGAGTAAAAAATTTAGCAATGAAAGTGATACAGATTTTATT
TTAGCGCAAAATAGAGTTTGGGCTAAAGAAATTAAAGCTAAATATGAAAATTTAAAAGATTATGATGTTTATCCTGTTAT
AGGTGAGCTTGATTTTAAAGCAGAAAATTTAAATGTTTTAGAAGTTAAAGATAAGATTGAAGATAGAGTGATAGGAAAGG
CTTATTTAGCAGGAGAAAAAGAAATCAAACAAGCTTTAGAAGTAGCTAAAAATTCCAAATTTACACAAAAAAGTCATGAT
GAAATTTATCAAATTTTAGCCAAAAGCGCAAAACTTATGAGAGAAAGAAGGGGAGATTTAATAGGTTTGGCAGCTTTAGA
AGTGGGCAAAACCTTTTTAGAGATCGATCCTGAAGTAAGTGAGGCTATTGATTTTATAGAGTTTTATCCGCACTCTTTAG
AAGAGCTTAAAAAACAAAATCCAAAAGTTAAATTCGCACCTAAGGGCATAGGGGTTACCATAGCTCCTTGGAATTTTCCT
GTAGGGATTTCAGTGGGCACCATAGCTGCACCACTAGCTGCAGGTAATGTGGTGATTTACAAACCTTCTTCACTTTCAAC
TCTAACAGGTTATATGCTTTGTAAGTGTTTTTGGGATGCAGGTATTCCAAAAGACGCTTTGATTTTCTTACCTTCAAAAG
GAAGTGATATTTCTAAATATTTACTTGTTGATGAAGCGATTAAATTTTCAATTCTTACAGGAGGAGAGGATACTGCTTAT
GCTATGTTAAAAGCTAATCCAACCTTGCTTTTAAGTGCTGAAACGGGCGGAAAGAATGCGACTATAGTTTCTAAATTTGC
TGATCGTGATAGTGCGATTAAAAATATCATTCATTCTGCTTTTAGCAATAGCGGTCAAAAATGTTCAGCTACTTCTTTGC
TAGTCTTAGAAGAAGAAGTTTATCATGATGAAGAATTTAAAAAGACTTTAGTAGATGCTGCAAGTTCTATGGCAGTAGGC
AATCCTTTTGAATTTAAAAATAAATTGGGTTCTTTAGCTGATAAGCCAAGTTCTAAAGTTCAAAAGGCCTTAGATGAATT
ACAACCTTATGAAGAATGGGCATTAAAACCTAAGTTTTTAGAGGATAATCCTTATTTGATGACTCCAGGCATAAAATATG
GCACTAAAAAGGGTGATTTTACTCATATGAATGAACTTTTTGTACCGATTTTAAGTGTAATGAAGGCTAAAGACTTAAAA
GAAGCTATTGATATAGTAAATTCCACAGGTTATGGTTTAACTGCAGGTTTTGAAAGCTTAGATGAAAGAGAATGGGAGTA
TTTTCACACTCACATAGAAGCAGGAAATATTTATATTAACAAACCAACCACAGGGGCTATAGTGCTGCGTCAACCTTTTG
GTGGGATTAAAAAATCTGCCATAGGTTTGGGTAGAAAAGTGGGAATTTATAATTATATCACTCAATTTTTAGAGATTAAG
CAAGAAGATTTTGATGATCATTTAATTGAAGATAAATTTTCAAAAAAATTAGCACAAATAGATTTAAAAGAAGCACAAGA
TTTTATGAACGATTTAATTAAAATGTCTCAATCTTATGCTTATCATTATAAAAATGAGTTTAGTGTTTCAAAAGATTATG
TCAATATTCGTGGAGAAGATAATCTTTTTTCTTATACTAAAATAAAGAATATGGTTTTAAGACTTTGTGGAAATGAAAGC
TTAAAAGATGTTTTAGGTGTGGTTTTAGGTGCAAATATTGCAAATATTGATCTAAGTATCAGTTATGATGAACAAGATGT
TAGTATGATAGAACGAATTGTTCAAAGCATAGGAGCAAAAGTATTGTTTTTAAAAGAAAATAAAGAAAATTTTATCAAGA
GTATTAAAGAATATGAAAGAGTGCGTTATTTAGCAAAGCCAGATGTAAATGATGAGATTTATAAAGAGGCTGCAAAGCTT
GCTAAAATCATTATAAGAGAAAAGCCATTATTAAATGGTCGTTTTGAACTTTTAAATTATTTTAATGAAAAAGCTTTAAG
TATATCTTTTCATCGTTATGGAAATTTAGGCATTAGAGCAATATCTTAA

Upstream 100 bases:

>100_bases
TTTTTATCATTTTTTATACATTTTCTATGATTTAAAATATTATTTTTATCTTATTTATATATTATTTATTAAAATTTAAT
TTTATCTTAGGAGATGCGAA

Downstream 100 bases:

>100_bases
TGATCAAGGAGAGATTGATGGAAGTGGTTCAAATTAATACCCCAATAGCAGTGATGTTTGTAGTGTATGCCTTATTAATG
CTTTATATAGGTTTTTATTT

Product: bifunctional putA protein

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1162; Mature: 1162

Protein sequence:

>1162_residues
MIQKALALAEELQGQIEANISNSEKEFHAKMQKLLNNPKNKVMLIELLDRSFRCKDKNASFELIEYTLSKYGIADFFSTF
EKFLLFSFLNFGKFAPNLSVPFFVKHLREDTKAMVLDANPSVLEPHINKRKEQDKIILNVNLIGEEVLGEAESKYRMQKY
EEALKSSYITYISIKITTIFSQINIIDFDYSKEEVVKRLDYLYALALEEEKKQGVSKFINLDMEEFRDLELTVAAFMESV
AKFDIKAGIVLQAYIPDSYKYLKKLFAFSKERVLKGMKPIKIRFVKGANMESEETIASQKGWELPTFYKKIDTDSNYNKM
LDFILEGDNYKYINIGIASHNIFEITYAYTRISEAGALDSFTFEMLEGMSLQCSYQLSKMHDLILYAPVCDEAHFNNAIA
YLVRRLDENTSEDNFMRYFFNLKVGDKNWNIQKELFLKSLEGIKTLDNTTHRKQDRNKEQNITSSYESKKFSNESDTDFI
LAQNRVWAKEIKAKYENLKDYDVYPVIGELDFKAENLNVLEVKDKIEDRVIGKAYLAGEKEIKQALEVAKNSKFTQKSHD
EIYQILAKSAKLMRERRGDLIGLAALEVGKTFLEIDPEVSEAIDFIEFYPHSLEELKKQNPKVKFAPKGIGVTIAPWNFP
VGISVGTIAAPLAAGNVVIYKPSSLSTLTGYMLCKCFWDAGIPKDALIFLPSKGSDISKYLLVDEAIKFSILTGGEDTAY
AMLKANPTLLLSAETGGKNATIVSKFADRDSAIKNIIHSAFSNSGQKCSATSLLVLEEEVYHDEEFKKTLVDAASSMAVG
NPFEFKNKLGSLADKPSSKVQKALDELQPYEEWALKPKFLEDNPYLMTPGIKYGTKKGDFTHMNELFVPILSVMKAKDLK
EAIDIVNSTGYGLTAGFESLDEREWEYFHTHIEAGNIYINKPTTGAIVLRQPFGGIKKSAIGLGRKVGIYNYITQFLEIK
QEDFDDHLIEDKFSKKLAQIDLKEAQDFMNDLIKMSQSYAYHYKNEFSVSKDYVNIRGEDNLFSYTKIKNMVLRLCGNES
LKDVLGVVLGANIANIDLSISYDEQDVSMIERIVQSIGAKVLFLKENKENFIKSIKEYERVRYLAKPDVNDEIYKEAAKL
AKIIIREKPLLNGRFELLNYFNEKALSISFHRYGNLGIRAIS

Sequences:

>Translated_1162_residues
MIQKALALAEELQGQIEANISNSEKEFHAKMQKLLNNPKNKVMLIELLDRSFRCKDKNASFELIEYTLSKYGIADFFSTF
EKFLLFSFLNFGKFAPNLSVPFFVKHLREDTKAMVLDANPSVLEPHINKRKEQDKIILNVNLIGEEVLGEAESKYRMQKY
EEALKSSYITYISIKITTIFSQINIIDFDYSKEEVVKRLDYLYALALEEEKKQGVSKFINLDMEEFRDLELTVAAFMESV
AKFDIKAGIVLQAYIPDSYKYLKKLFAFSKERVLKGMKPIKIRFVKGANMESEETIASQKGWELPTFYKKIDTDSNYNKM
LDFILEGDNYKYINIGIASHNIFEITYAYTRISEAGALDSFTFEMLEGMSLQCSYQLSKMHDLILYAPVCDEAHFNNAIA
YLVRRLDENTSEDNFMRYFFNLKVGDKNWNIQKELFLKSLEGIKTLDNTTHRKQDRNKEQNITSSYESKKFSNESDTDFI
LAQNRVWAKEIKAKYENLKDYDVYPVIGELDFKAENLNVLEVKDKIEDRVIGKAYLAGEKEIKQALEVAKNSKFTQKSHD
EIYQILAKSAKLMRERRGDLIGLAALEVGKTFLEIDPEVSEAIDFIEFYPHSLEELKKQNPKVKFAPKGIGVTIAPWNFP
VGISVGTIAAPLAAGNVVIYKPSSLSTLTGYMLCKCFWDAGIPKDALIFLPSKGSDISKYLLVDEAIKFSILTGGEDTAY
AMLKANPTLLLSAETGGKNATIVSKFADRDSAIKNIIHSAFSNSGQKCSATSLLVLEEEVYHDEEFKKTLVDAASSMAVG
NPFEFKNKLGSLADKPSSKVQKALDELQPYEEWALKPKFLEDNPYLMTPGIKYGTKKGDFTHMNELFVPILSVMKAKDLK
EAIDIVNSTGYGLTAGFESLDEREWEYFHTHIEAGNIYINKPTTGAIVLRQPFGGIKKSAIGLGRKVGIYNYITQFLEIK
QEDFDDHLIEDKFSKKLAQIDLKEAQDFMNDLIKMSQSYAYHYKNEFSVSKDYVNIRGEDNLFSYTKIKNMVLRLCGNES
LKDVLGVVLGANIANIDLSISYDEQDVSMIERIVQSIGAKVLFLKENKENFIKSIKEYERVRYLAKPDVNDEIYKEAAKL
AKIIIREKPLLNGRFELLNYFNEKALSISFHRYGNLGIRAIS
>Mature_1162_residues
MIQKALALAEELQGQIEANISNSEKEFHAKMQKLLNNPKNKVMLIELLDRSFRCKDKNASFELIEYTLSKYGIADFFSTF
EKFLLFSFLNFGKFAPNLSVPFFVKHLREDTKAMVLDANPSVLEPHINKRKEQDKIILNVNLIGEEVLGEAESKYRMQKY
EEALKSSYITYISIKITTIFSQINIIDFDYSKEEVVKRLDYLYALALEEEKKQGVSKFINLDMEEFRDLELTVAAFMESV
AKFDIKAGIVLQAYIPDSYKYLKKLFAFSKERVLKGMKPIKIRFVKGANMESEETIASQKGWELPTFYKKIDTDSNYNKM
LDFILEGDNYKYINIGIASHNIFEITYAYTRISEAGALDSFTFEMLEGMSLQCSYQLSKMHDLILYAPVCDEAHFNNAIA
YLVRRLDENTSEDNFMRYFFNLKVGDKNWNIQKELFLKSLEGIKTLDNTTHRKQDRNKEQNITSSYESKKFSNESDTDFI
LAQNRVWAKEIKAKYENLKDYDVYPVIGELDFKAENLNVLEVKDKIEDRVIGKAYLAGEKEIKQALEVAKNSKFTQKSHD
EIYQILAKSAKLMRERRGDLIGLAALEVGKTFLEIDPEVSEAIDFIEFYPHSLEELKKQNPKVKFAPKGIGVTIAPWNFP
VGISVGTIAAPLAAGNVVIYKPSSLSTLTGYMLCKCFWDAGIPKDALIFLPSKGSDISKYLLVDEAIKFSILTGGEDTAY
AMLKANPTLLLSAETGGKNATIVSKFADRDSAIKNIIHSAFSNSGQKCSATSLLVLEEEVYHDEEFKKTLVDAASSMAVG
NPFEFKNKLGSLADKPSSKVQKALDELQPYEEWALKPKFLEDNPYLMTPGIKYGTKKGDFTHMNELFVPILSVMKAKDLK
EAIDIVNSTGYGLTAGFESLDEREWEYFHTHIEAGNIYINKPTTGAIVLRQPFGGIKKSAIGLGRKVGIYNYITQFLEIK
QEDFDDHLIEDKFSKKLAQIDLKEAQDFMNDLIKMSQSYAYHYKNEFSVSKDYVNIRGEDNLFSYTKIKNMVLRLCGNES
LKDVLGVVLGANIANIDLSISYDEQDVSMIERIVQSIGAKVLFLKENKENFIKSIKEYERVRYLAKPDVNDEIYKEAAKL
AKIIIREKPLLNGRFELLNYFNEKALSISFHRYGNLGIRAIS

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=465, Percent_Identity=26.6666666666667, Blast_Score=141, Evalue=4e-33,
Organism=Homo sapiens, GI115387104, Length=444, Percent_Identity=25.4504504504505, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI238859541, Length=423, Percent_Identity=30.0236406619385, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI153266822, Length=415, Percent_Identity=27.9518072289157, Blast_Score=134, Evalue=6e-31,
Organism=Homo sapiens, GI25777736, Length=423, Percent_Identity=30.0236406619385, Blast_Score=134, Evalue=7e-31,
Organism=Homo sapiens, GI25777734, Length=423, Percent_Identity=30.0236406619385, Blast_Score=134, Evalue=7e-31,
Organism=Homo sapiens, GI25777730, Length=450, Percent_Identity=27.3333333333333, Blast_Score=133, Evalue=9e-31,
Organism=Homo sapiens, GI25777732, Length=341, Percent_Identity=27.5659824046921, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI21361176, Length=342, Percent_Identity=28.6549707602339, Blast_Score=121, Evalue=4e-27,
Organism=Homo sapiens, GI25777724, Length=495, Percent_Identity=25.6565656565657, Blast_Score=120, Evalue=7e-27,
Organism=Homo sapiens, GI25777728, Length=417, Percent_Identity=26.8585131894484, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI238814322, Length=425, Percent_Identity=24.7058823529412, Blast_Score=117, Evalue=7e-26,
Organism=Homo sapiens, GI21614513, Length=442, Percent_Identity=24.2081447963801, Blast_Score=117, Evalue=8e-26,
Organism=Homo sapiens, GI25952152, Length=454, Percent_Identity=23.568281938326, Blast_Score=106, Evalue=2e-22,
Organism=Homo sapiens, GI25777726, Length=491, Percent_Identity=25.2545824847251, Blast_Score=105, Evalue=4e-22,
Organism=Homo sapiens, GI4507229, Length=426, Percent_Identity=26.5258215962441, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI25777721, Length=439, Percent_Identity=25.7403189066059, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI11095441, Length=427, Percent_Identity=23.6533957845433, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI188035924, Length=406, Percent_Identity=26.1083743842365, Blast_Score=82, Evalue=4e-15,
Organism=Homo sapiens, GI301500698, Length=282, Percent_Identity=26.5957446808511, Blast_Score=81, Evalue=5e-15,
Organism=Homo sapiens, GI310128103, Length=406, Percent_Identity=26.1083743842365, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI310128093, Length=406, Percent_Identity=26.1083743842365, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI310128091, Length=385, Percent_Identity=26.2337662337662, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI206597441, Length=409, Percent_Identity=23.4718826405868, Blast_Score=75, Evalue=5e-13,
Organism=Homo sapiens, GI206597439, Length=409, Percent_Identity=23.4718826405868, Blast_Score=75, Evalue=5e-13,
Organism=Homo sapiens, GI22907049, Length=409, Percent_Identity=23.4718826405868, Blast_Score=75, Evalue=5e-13,
Organism=Homo sapiens, GI73466520, Length=406, Percent_Identity=22.4137931034483, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI4557303, Length=406, Percent_Identity=22.4137931034483, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI73695881, Length=332, Percent_Identity=23.7951807228916, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI73695879, Length=332, Percent_Identity=23.7951807228916, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4502043, Length=332, Percent_Identity=23.7951807228916, Blast_Score=72, Evalue=3e-12,
Organism=Homo sapiens, GI238814371, Length=332, Percent_Identity=23.7951807228916, Blast_Score=72, Evalue=3e-12,
Organism=Homo sapiens, GI71773324, Length=332, Percent_Identity=23.7951807228916, Blast_Score=72, Evalue=4e-12,
Organism=Escherichia coli, GI1787250, Length=844, Percent_Identity=27.0142180094787, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI1788042, Length=436, Percent_Identity=27.7522935779816, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1789015, Length=463, Percent_Identity=27.2138228941685, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1786504, Length=478, Percent_Identity=26.3598326359833, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI87081926, Length=441, Percent_Identity=24.2630385487528, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1787558, Length=482, Percent_Identity=25.7261410788382, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI87081896, Length=343, Percent_Identity=27.4052478134111, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI87082295, Length=484, Percent_Identity=25.4132231404959, Blast_Score=106, Evalue=8e-24,
Organism=Escherichia coli, GI1787684, Length=407, Percent_Identity=25.0614250614251, Blast_Score=100, Evalue=9e-22,
Organism=Escherichia coli, GI1787715, Length=343, Percent_Identity=24.4897959183673, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25143874, Length=432, Percent_Identity=27.7777777777778, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25143876, Length=432, Percent_Identity=28.4722222222222, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17551164, Length=427, Percent_Identity=28.3372365339578, Blast_Score=124, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17562198, Length=445, Percent_Identity=25.8426966292135, Blast_Score=123, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI133930964, Length=443, Percent_Identity=25.7336343115124, Blast_Score=119, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25144435, Length=482, Percent_Identity=23.2365145228216, Blast_Score=111, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32564736, Length=426, Percent_Identity=24.6478873239437, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17534447, Length=468, Percent_Identity=28.2051282051282, Blast_Score=104, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71986308, Length=490, Percent_Identity=23.6734693877551, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI115534176, Length=398, Percent_Identity=27.1356783919598, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17534119, Length=447, Percent_Identity=24.8322147651007, Blast_Score=97, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71995606, Length=469, Percent_Identity=24.0938166311301, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115532534, Length=406, Percent_Identity=27.8325123152709, Blast_Score=94, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17564084, Length=345, Percent_Identity=25.5072463768116, Blast_Score=90, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI32564151, Length=403, Percent_Identity=26.7990074441687, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25146391, Length=386, Percent_Identity=24.0932642487047, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25146394, Length=386, Percent_Identity=24.0932642487047, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32566756, Length=386, Percent_Identity=24.0932642487047, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71995613, Length=422, Percent_Identity=23.9336492890995, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71990744, Length=269, Percent_Identity=29.368029739777, Blast_Score=79, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320917, Length=337, Percent_Identity=30.8605341246291, Blast_Score=135, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6321826, Length=442, Percent_Identity=28.7330316742081, Blast_Score=134, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6325196, Length=477, Percent_Identity=25.3668763102725, Blast_Score=130, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6323821, Length=458, Percent_Identity=26.8558951965066, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6323822, Length=440, Percent_Identity=26.5909090909091, Blast_Score=124, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324950, Length=463, Percent_Identity=25.9179265658747, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319478, Length=454, Percent_Identity=24.8898678414097, Blast_Score=105, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6321828, Length=354, Percent_Identity=26.271186440678, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323757, Length=370, Percent_Identity=26.4864864864865, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24668425, Length=515, Percent_Identity=28.3495145631068, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24668417, Length=515, Percent_Identity=28.3495145631068, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24668413, Length=515, Percent_Identity=28.3495145631068, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24585660, Length=461, Percent_Identity=25.1626898047722, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI20129399, Length=474, Percent_Identity=24.6835443037975, Blast_Score=122, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24650465, Length=424, Percent_Identity=27.3584905660377, Blast_Score=117, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28571806, Length=483, Percent_Identity=23.3954451345756, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571802, Length=485, Percent_Identity=23.5051546391753, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571800, Length=485, Percent_Identity=23.5051546391753, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571798, Length=485, Percent_Identity=23.5051546391753, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571796, Length=485, Percent_Identity=23.5051546391753, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571794, Length=485, Percent_Identity=23.5051546391753, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281362580, Length=465, Percent_Identity=24.9462365591398, Blast_Score=114, Evalue=4e-25,
Organism=Drosophila melanogaster, GI62472918, Length=465, Percent_Identity=24.9462365591398, Blast_Score=114, Evalue=4e-25,
Organism=Drosophila melanogaster, GI62472926, Length=465, Percent_Identity=24.9462365591398, Blast_Score=114, Evalue=4e-25,
Organism=Drosophila melanogaster, GI62472936, Length=465, Percent_Identity=24.9462365591398, Blast_Score=114, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21356737, Length=465, Percent_Identity=24.9462365591398, Blast_Score=114, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24666674, Length=486, Percent_Identity=24.2798353909465, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24638878, Length=429, Percent_Identity=24.009324009324, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24638876, Length=429, Percent_Identity=24.009324009324, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574525, Length=341, Percent_Identity=23.4604105571848, Blast_Score=68, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 132518; Mature: 132518

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQKALALAEELQGQIEANISNSEKEFHAKMQKLLNNPKNKVMLIELLDRSFRCKDKNAS
CCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEHEECCCCCCCCCCCCC
FELIEYTLSKYGIADFFSTFEKFLLFSFLNFGKFAPNLSVPFFVKHLREDTKAMVLDANP
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCC
SVLEPHINKRKEQDKIILNVNLIGEEVLGEAESKYRMQKYEEALKSSYITYISIKITTIF
CCCCCCHHCCCCCCEEEEEEEECCHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEEE
SQINIIDFDYSKEEVVKRLDYLYALALEEEKKQGVSKFINLDMEEFRDLELTVAAFMESV
HHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHH
AKFDIKAGIVLQAYIPDSYKYLKKLFAFSKERVLKGMKPIKIRFVKGANMESEETIASQK
HHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCC
GWELPTFYKKIDTDSNYNKMLDFILEGDNYKYINIGIASHNIFEITYAYTRISEAGALDS
CCCCCHHHHHCCCCCCHHHHHHHEEECCCEEEEEEEEECCCEEEEEEHHHHHHHCCCCHH
FTFEMLEGMSLQCSYQLSKMHDLILYAPVCDEAHFNNAIAYLVRRLDENTSEDNFMRYFF
HHHHHHCCCCEEEEEEHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEE
NLKVGDKNWNIQKELFLKSLEGIKTLDNTTHRKQDRNKEQNITSSYESKKFSNESDTDFI
EEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHCCHHHHHHHCCCCCCCCCEE
LAQNRVWAKEIKAKYENLKDYDVYPVIGELDFKAENLNVLEVKDKIEDRVIGKAYLAGEK
EECCCHHHHHHHHHHHCCCCCCCEEEEECCEECCCCCEEEEEHHHHHHHHHHHHHHCCHH
EIKQALEVAKNSKFTQKSHDEIYQILAKSAKLMRERRGDLIGLAALEVGKTFLEIDPEVS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCHHEECCCCHH
EAIDFIEFYPHSLEELKKQNPKVKFAPKGIGVTIAPWNFPVGISVGTIAAPLAAGNVVIY
HHHHHHHHCCHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEEEE
KPSSLSTLTGYMLCKCFWDAGIPKDALIFLPSKGSDISKYLLVDEAIKFSILTGGEDTAY
CCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCEEEEEEECCCCCEE
AMLKANPTLLLSAETGGKNATIVSKFADRDSAIKNIIHSAFSNSGQKCSATSLLVLEEEV
EEEECCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHH
YHDEEFKKTLVDAASSMAVGNPFEFKNKLGSLADKPSSKVQKALDELQPYEEWALKPKFL
HCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCCCEE
EDNPYLMTPGIKYGTKKGDFTHMNELFVPILSVMKAKDLKEAIDIVNSTGYGLTAGFESL
CCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
DEREWEYFHTHIEAGNIYINKPTTGAIVLRQPFGGIKKSAIGLGRKVGIYNYITQFLEIK
HHHHHHHHHEEEEECEEEEECCCCCEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHH
QEDFDDHLIEDKFSKKLAQIDLKEAQDFMNDLIKMSQSYAYHYKNEFSVSKDYVNIRGED
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCC
NLFSYTKIKNMVLRLCGNESLKDVLGVVLGANIANIDLSISYDEQDVSMIERIVQSIGAK
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHCCCE
VLFLKENKENFIKSIKEYERVRYLAKPDVNDEIYKEAAKLAKIIIREKPLLNGRFELLNY
EEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
FNEKALSISFHRYGNLGIRAIS
HCCCCEEEEEEECCCCCEEEEC
>Mature Secondary Structure
MIQKALALAEELQGQIEANISNSEKEFHAKMQKLLNNPKNKVMLIELLDRSFRCKDKNAS
CCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEHEECCCCCCCCCCCCC
FELIEYTLSKYGIADFFSTFEKFLLFSFLNFGKFAPNLSVPFFVKHLREDTKAMVLDANP
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCC
SVLEPHINKRKEQDKIILNVNLIGEEVLGEAESKYRMQKYEEALKSSYITYISIKITTIF
CCCCCCHHCCCCCCEEEEEEEECCHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEEE
SQINIIDFDYSKEEVVKRLDYLYALALEEEKKQGVSKFINLDMEEFRDLELTVAAFMESV
HHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHH
AKFDIKAGIVLQAYIPDSYKYLKKLFAFSKERVLKGMKPIKIRFVKGANMESEETIASQK
HHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCC
GWELPTFYKKIDTDSNYNKMLDFILEGDNYKYINIGIASHNIFEITYAYTRISEAGALDS
CCCCCHHHHHCCCCCCHHHHHHHEEECCCEEEEEEEEECCCEEEEEEHHHHHHHCCCCHH
FTFEMLEGMSLQCSYQLSKMHDLILYAPVCDEAHFNNAIAYLVRRLDENTSEDNFMRYFF
HHHHHHCCCCEEEEEEHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEE
NLKVGDKNWNIQKELFLKSLEGIKTLDNTTHRKQDRNKEQNITSSYESKKFSNESDTDFI
EEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHCCHHHHHHHCCCCCCCCCEE
LAQNRVWAKEIKAKYENLKDYDVYPVIGELDFKAENLNVLEVKDKIEDRVIGKAYLAGEK
EECCCHHHHHHHHHHHCCCCCCCEEEEECCEECCCCCEEEEEHHHHHHHHHHHHHHCCHH
EIKQALEVAKNSKFTQKSHDEIYQILAKSAKLMRERRGDLIGLAALEVGKTFLEIDPEVS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCHHEECCCCHH
EAIDFIEFYPHSLEELKKQNPKVKFAPKGIGVTIAPWNFPVGISVGTIAAPLAAGNVVIY
HHHHHHHHCCHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEEEE
KPSSLSTLTGYMLCKCFWDAGIPKDALIFLPSKGSDISKYLLVDEAIKFSILTGGEDTAY
CCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCEEEEEEECCCCCEE
AMLKANPTLLLSAETGGKNATIVSKFADRDSAIKNIIHSAFSNSGQKCSATSLLVLEEEV
EEEECCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHH
YHDEEFKKTLVDAASSMAVGNPFEFKNKLGSLADKPSSKVQKALDELQPYEEWALKPKFL
HCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCCCEE
EDNPYLMTPGIKYGTKKGDFTHMNELFVPILSVMKAKDLKEAIDIVNSTGYGLTAGFESL
CCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
DEREWEYFHTHIEAGNIYINKPTTGAIVLRQPFGGIKKSAIGLGRKVGIYNYITQFLEIK
HHHHHHHHHEEEEECEEEEECCCCCEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHH
QEDFDDHLIEDKFSKKLAQIDLKEAQDFMNDLIKMSQSYAYHYKNEFSVSKDYVNIRGED
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCC
NLFSYTKIKNMVLRLCGNESLKDVLGVVLGANIANIDLSISYDEQDVSMIERIVQSIGAK
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHCCCE
VLFLKENKENFIKSIKEYERVRYLAKPDVNDEIYKEAAKLAKIIIREKPLLNGRFELLNY
EEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
FNEKALSISFHRYGNLGIRAIS
HCCCCEEEEEEECCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]