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The map label for this gene is gcp [H]

Identifier: 57238387

GI number: 57238387

Start: 1429176

End: 1430183

Strand: Reverse

Name: gcp [H]

Synonym: CJE1533

Alternate gene names: 57238387

Gene position: 1430183-1429176 (Counterclockwise)

Preceding gene: 57238388

Following gene: 57238386

Centisome position: 80.45

GC content: 31.55

Gene sequence:

>1008_bases
ATGAAAAATCTTATCCTAGCTATAGAAAGTTCTTGTGATGATAGTTCTATAGCTATCATTGATAAAAATACATTAGAATG
TAAATTTCATAAAAAAATTTCCCAAGAATTAGATCATAGTATCTATGGGGGAGTGGTACCTGAACTTGCTGCAAGACTTC
ATAGCGAGGCTTTACCAAAGATGCTTAAGCAATGCAAAGAGCATTTTAAAAATCTTTGTGCCATAGCTGTGACAAATGAA
CCTGGACTTAGTGTTTCTTTGCTCAGTGGAATTTCTATGGCAAAAACCTTAGCAAGTGCGCTAAATTTACCCTTAATCCC
TATAAATCATCTTAAAGGTCATATTTATAGTCTTTTTTTGGAAGAAAAAATTTCTTTAGATATGGGAATTTTGCTTGTTA
GTGGTGGGCATACCATGGTGCTTTATCTTAAAGATGACGCAAGTTTAGAGCTTTTAGCAAGTACAAATGATGATAGCTTT
GGAGAAAGTTTTGATAAAGTGGCTAAAATGATGAATTTAGGTTACCCTGGTGGGGTCATCATAGAAAATTTAGCAAAAAA
TGCCAAACTTAAAAATATCTCTTTTAACACACCTTTAAAGCATTCTAAAGAACTCGCTTTCAGTTTTTCAGGGCTTAAAA
ATGCAGTGCGTTTGGAAATTTTAAAACATGAAAATTTAAATGAAGACACAAAAGCAGAAATAGCTTATGCCTTTGAAAAT
ACAGCTTGTGATCATATCATGGATAAATTAGAAAAAATTTTTAATCTTTATAAATTTAAAAATTTTGGCGTTGTAGGTGG
AGCTAGTGCAAATCTTAACTTGCGTTCGCGTTTGCAAAATTTATGTCAAAAATATAATGCAAATTTAAAACTAGCTCCTT
TAAAATTCTGCTCTGATAATGCTTTGATGATAGCAAGAGCCGCAGTTGATGCTTATGAAAAAAAGGAATTTGTAAGTGTA
GAAGAAGATATTTTAAGCCCTAAAAATAAAAATTTTTCAAGGATATAG

Upstream 100 bases:

>100_bases
ATAGCAAGTTGATCAAAAACGCTAAAAATTTGGATTTAAATACTCTTAAAATGGCAAGATCAAAAGATAAATTCTTAGGT
TCTATTTTAGTGGAATTTGA

Downstream 100 bases:

>100_bases
ATGAAAAAAGCTTTTACTATATTAGAACTTGTTTTTGTGATCGTTATTTTGGGAATTTTAGCCGCTATTGCTTTGCCAAA
AATGAGTTCAAGTAAGGATG

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKNLILAIESSCDDSSIAIIDKNTLECKFHKKISQELDHSIYGGVVPELAARLHSEALPKMLKQCKEHFKNLCAIAVTNE
PGLSVSLLSGISMAKTLASALNLPLIPINHLKGHIYSLFLEEKISLDMGILLVSGGHTMVLYLKDDASLELLASTNDDSF
GESFDKVAKMMNLGYPGGVIIENLAKNAKLKNISFNTPLKHSKELAFSFSGLKNAVRLEILKHENLNEDTKAEIAYAFEN
TACDHIMDKLEKIFNLYKFKNFGVVGGASANLNLRSRLQNLCQKYNANLKLAPLKFCSDNALMIARAAVDAYEKKEFVSV
EEDILSPKNKNFSRI

Sequences:

>Translated_335_residues
MKNLILAIESSCDDSSIAIIDKNTLECKFHKKISQELDHSIYGGVVPELAARLHSEALPKMLKQCKEHFKNLCAIAVTNE
PGLSVSLLSGISMAKTLASALNLPLIPINHLKGHIYSLFLEEKISLDMGILLVSGGHTMVLYLKDDASLELLASTNDDSF
GESFDKVAKMMNLGYPGGVIIENLAKNAKLKNISFNTPLKHSKELAFSFSGLKNAVRLEILKHENLNEDTKAEIAYAFEN
TACDHIMDKLEKIFNLYKFKNFGVVGGASANLNLRSRLQNLCQKYNANLKLAPLKFCSDNALMIARAAVDAYEKKEFVSV
EEDILSPKNKNFSRI
>Mature_335_residues
MKNLILAIESSCDDSSIAIIDKNTLECKFHKKISQELDHSIYGGVVPELAARLHSEALPKMLKQCKEHFKNLCAIAVTNE
PGLSVSLLSGISMAKTLASALNLPLIPINHLKGHIYSLFLEEKISLDMGILLVSGGHTMVLYLKDDASLELLASTNDDSF
GESFDKVAKMMNLGYPGGVIIENLAKNAKLKNISFNTPLKHSKELAFSFSGLKNAVRLEILKHENLNEDTKAEIAYAFEN
TACDHIMDKLEKIFNLYKFKNFGVVGGASANLNLRSRLQNLCQKYNANLKLAPLKFCSDNALMIARAAVDAYEKKEFVSV
EEDILSPKNKNFSRI

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=338, Percent_Identity=29.585798816568, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI8923380, Length=280, Percent_Identity=26.4285714285714, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI1789445, Length=312, Percent_Identity=36.5384615384615, Blast_Score=202, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17557464, Length=321, Percent_Identity=29.595015576324, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71995670, Length=323, Percent_Identity=26.0061919504644, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320099, Length=353, Percent_Identity=31.4447592067989, Blast_Score=135, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6322891, Length=298, Percent_Identity=24.8322147651007, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI20129063, Length=356, Percent_Identity=29.7752808988764, Blast_Score=147, Evalue=9e-36,
Organism=Drosophila melanogaster, GI21357207, Length=345, Percent_Identity=25.7971014492754, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37066; Mature: 37066

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLILAIESSCDDSSIAIIDKNTLECKFHKKISQELDHSIYGGVVPELAARLHSEALPK
CCCEEEEEECCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
MLKQCKEHFKNLCAIAVTNEPGLSVSLLSGISMAKTLASALNLPLIPINHLKGHIYSLFL
HHHHHHHHHHHHEEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
EEKISLDMGILLVSGGHTMVLYLKDDASLELLASTNDDSFGESFDKVAKMMNLGYPGGVI
HHHHCCCEEEEEEECCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHH
IENLAKNAKLKNISFNTPLKHSKELAFSFSGLKNAVRLEILKHENLNEDTKAEIAYAFEN
HHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCHHHEEEEECCCCCCCCCHHHEEEEHHC
TACDHIMDKLEKIFNLYKFKNFGVVGGASANLNLRSRLQNLCQKYNANLKLAPLKFCSDN
CCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCC
ALMIARAAVDAYEKKEFVSVEEDILSPKNKNFSRI
CEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKNLILAIESSCDDSSIAIIDKNTLECKFHKKISQELDHSIYGGVVPELAARLHSEALPK
CCCEEEEEECCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
MLKQCKEHFKNLCAIAVTNEPGLSVSLLSGISMAKTLASALNLPLIPINHLKGHIYSLFL
HHHHHHHHHHHHEEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
EEKISLDMGILLVSGGHTMVLYLKDDASLELLASTNDDSFGESFDKVAKMMNLGYPGGVI
HHHHCCCEEEEEEECCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHH
IENLAKNAKLKNISFNTPLKHSKELAFSFSGLKNAVRLEILKHENLNEDTKAEIAYAFEN
HHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCHHHEEEEECCCCCCCCCHHHEEEEHHC
TACDHIMDKLEKIFNLYKFKNFGVVGGASANLNLRSRLQNLCQKYNANLKLAPLKFCSDN
CCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCC
ALMIARAAVDAYEKKEFVSVEEDILSPKNKNFSRI
CEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA