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The map label for this gene is clpB [H]

Identifier: 57238288

GI number: 57238288

Start: 553086

End: 555659

Strand: Reverse

Name: clpB [H]

Synonym: CJE0616

Alternate gene names: 57238288

Gene position: 555659-553086 (Counterclockwise)

Preceding gene: 57238287

Following gene: 57238292

Centisome position: 31.25

GC content: 32.4

Gene sequence:

>2574_bases
ATGGCAAATATACAAGATTTTTTAACTGATAATATGCTTTCAAACCTTGAAAGTGCAGCATCTTTAGCTATACATTCTAA
AAATACTGAAGTCGTACCTTTGCACCTTTTATGGGCTTTAAGCGTAGATAGTACAAGTATTTTAAATCAAATTTTAAATA
AATTAAATATTTCTAAAGAAGCCTTAGAACTTGAAATTAAAAGCAGAATTTCAAAACTTGCAACGAGTTCAAATGTAAAC
CGTGAAAATATACGCTTTTCCAATGAACTTATAAATTCATTAGAAAATGCTAAAGGATTAATGAGTGCTAATGGAGATAG
TTATTTAAGTGTGGATACTTGGCTTATAAGTGAAAGTCAAAAAAGTCCTATTAAAGAAATTTTGGCGCAATTTTTAGATT
TAAGAGAATTTCAAAAAGAGCTTGAAAGTCTAAGAGCGGGACGAAAAATGGATAGCAAAACAAGCGATGAAACTTTAGAT
AGCTTAAATAAATTTGGTATAGATTTAACCTTAAAGGCAAGCGAGGGTAAACTTGATCCTGTTATAGGCAGAGAAGAAGA
AATCGAACGTTTGATGCAAATTTTAATACGCAAAACCAAAAACAACCCTATACTTTTAGGTGAACCAGGCGTAGGAAAAA
CAGCTATAGTAGAAGCTTTAGCACAAAGAATTATTAAAAAAGATGTTCCAAAATCTTTGCAAAATAAAAAAGTCATCGCT
CTTGATATGAGTGCTTTAATTGCAGGTGCAAAATACAGAGGAGAATTTGAAGATAGATTAAAAGCTGTGGTTAATGAAGT
GATAAAAAGTGAAAATATCATTCTTTTTATCGATGAAATTCACACTATAGTAGGAGCTGGAGCGAGTGAAGGCAGCATGG
ATGCGGCAAATATTTTAAAACCTGCTCTTGCAAGAGGTGAACTCCATACCATAGGCGCAACTACTTTAAAAGAATATCGT
AAATATTTTGAAAAAGATGCAGCCTTGCAACGCCGTTTTCAACCTGTAAATGTAGGTGAGCCAAGTGTTAATGAGGCTTT
GGCTATGTTAAGGGGTATAAAAGAAAAGCTTGAAATTCATCATAATGTAACCATAAATGATAGTGCTTTAGTAGCCGCAG
CTAAACTTTCAAAGCGTTATATAACAGATCGTTTTTTACCTGATAAGGCCATTGATTTAATCGATGAAGCTGCAGCTGAA
CTAAAAATGCAAATTGAAAGCGAACCAAGTTCTTTAAGAAAAGTACGCAAAGATATAGAAACTTTAGAAGTTGAAAATGA
AGCTTTAAAAATGGAAAATGATGAAAAAAATCAAAAAAGACTCGATGAAATCGCAAAAGAACTAGCTAATTTAAAAGAAA
AACAAAATGCCCTAAATTCACAGTTTGAAAATGAAAAAAGTGTTTTTGATGGCATAAGTGCTAAGAAAAAAGAAATTGAT
CTGCTTAAAAATGAAGCTTCTTTGGCTAAAGCTAGAGGTGAATTTCAAAAAGCAGCCGAGCTAGAGTATGGAAAAATTCC
AAGTCTTGAAAAAGAAGTAGAAATTTTAGAAGATAAATGGAAAAAAATGAGTGAAAATGGAGTTTTACTTAAAAATCAAG
TGGATGAGGATTTGGTTGCTGGAATTTTAAGCAAATGGACGGGTATTAGCGTGCAAAAAATGTTAACTTCTGAAAAACAA
AAATTCTTAGAAGTGGAAAAACATTTAAAAGAAAGTGTCATAGGACAAGATAAGGCCTTAAGTGCTTTAGCTAGAGCCAT
TAAACGTAATAAAGCGGGGCTTAATGCGGACAATAAACCTATAGGAAGCTTTTTATTTTTAGGGCCAACAGGGGTAGGAA
AAACACAATCGGCTAAAGCTTTGGCAAAATTTTTATTTGATGATGAAAAAGCAATGATTCGCTTTGATATGAGTGAATTT
ATGGAAAAACATAGTGTTTCAAGACTCTTAGGTGCGCCTCCAGGATATATAGGACATGAAGAAGGTGGAGAGCTTACTGA
AGCCGTACGAAGAAAACCTTATAGCGTGCTTTTGTTTGATGAAGTTGAAAAAGCACATAAAGATGTATTTAATGTGCTTT
TAGGGATTTTAGATGATAGTAGAGCAACCGATAGTAAAGGTGTAACAGTGGATTTTAAAAATACCATTATCATTTTAACT
TCTAATATCGCCTCAAGCGCCATTATGAATTTAAGCGGAAAAGAACAAGAAGATGCGGTAAAAAATGAGTTAAAAAATTT
CTTTAAACCTGAGTTTTTAAACCGTTTAGATGATATTATCACCTTTAATCCACTTGGAAAAGATGAAGCTTATGAAATAG
TCAAGCTTTTATTTAAAGATTTACAAATGAGCTTAGAAAACAAGGGAATAAAAGCAAGTTTAAGCGAAAATGCAGCCCTT
TTAATCGCTAAAGATGGTTTTGACCCTGATTTTGGTGCTAGACCTTTAAGAAGAGCTATTTATGATCTTATAGAAGATAA
ATTAAGCGATATGATACTTGCTGATGAACTTCATGAAAATGATAGCATTATCATTGATGCAAAAGATGATGAAATAATCA
TCAAAAAAGCTTAA

Upstream 100 bases:

>100_bases
TCATTTGTCTTATTATTTAAAAAATTTTACTCAATTAACTTGACATTATATGACTAAAGTTATATAATAGCAAGTATATA
AACTAAATAAAGGATAAAAC

Downstream 100 bases:

>100_bases
TCATTTTGAAAGTAGATCTTTCTACTTTCAAAATATAATCTCGCTTTCATTAAATTTCATATTTGCTTTTGGTAATGGTG
ATTTGGTGGTATAATAAGCA

Product: ATP-dependent chaperone protein ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 857; Mature: 856

Protein sequence:

>857_residues
MANIQDFLTDNMLSNLESAASLAIHSKNTEVVPLHLLWALSVDSTSILNQILNKLNISKEALELEIKSRISKLATSSNVN
RENIRFSNELINSLENAKGLMSANGDSYLSVDTWLISESQKSPIKEILAQFLDLREFQKELESLRAGRKMDSKTSDETLD
SLNKFGIDLTLKASEGKLDPVIGREEEIERLMQILIRKTKNNPILLGEPGVGKTAIVEALAQRIIKKDVPKSLQNKKVIA
LDMSALIAGAKYRGEFEDRLKAVVNEVIKSENIILFIDEIHTIVGAGASEGSMDAANILKPALARGELHTIGATTLKEYR
KYFEKDAALQRRFQPVNVGEPSVNEALAMLRGIKEKLEIHHNVTINDSALVAAAKLSKRYITDRFLPDKAIDLIDEAAAE
LKMQIESEPSSLRKVRKDIETLEVENEALKMENDEKNQKRLDEIAKELANLKEKQNALNSQFENEKSVFDGISAKKKEID
LLKNEASLAKARGEFQKAAELEYGKIPSLEKEVEILEDKWKKMSENGVLLKNQVDEDLVAGILSKWTGISVQKMLTSEKQ
KFLEVEKHLKESVIGQDKALSALARAIKRNKAGLNADNKPIGSFLFLGPTGVGKTQSAKALAKFLFDDEKAMIRFDMSEF
MEKHSVSRLLGAPPGYIGHEEGGELTEAVRRKPYSVLLFDEVEKAHKDVFNVLLGILDDSRATDSKGVTVDFKNTIIILT
SNIASSAIMNLSGKEQEDAVKNELKNFFKPEFLNRLDDIITFNPLGKDEAYEIVKLLFKDLQMSLENKGIKASLSENAAL
LIAKDGFDPDFGARPLRRAIYDLIEDKLSDMILADELHENDSIIIDAKDDEIIIKKA

Sequences:

>Translated_857_residues
MANIQDFLTDNMLSNLESAASLAIHSKNTEVVPLHLLWALSVDSTSILNQILNKLNISKEALELEIKSRISKLATSSNVN
RENIRFSNELINSLENAKGLMSANGDSYLSVDTWLISESQKSPIKEILAQFLDLREFQKELESLRAGRKMDSKTSDETLD
SLNKFGIDLTLKASEGKLDPVIGREEEIERLMQILIRKTKNNPILLGEPGVGKTAIVEALAQRIIKKDVPKSLQNKKVIA
LDMSALIAGAKYRGEFEDRLKAVVNEVIKSENIILFIDEIHTIVGAGASEGSMDAANILKPALARGELHTIGATTLKEYR
KYFEKDAALQRRFQPVNVGEPSVNEALAMLRGIKEKLEIHHNVTINDSALVAAAKLSKRYITDRFLPDKAIDLIDEAAAE
LKMQIESEPSSLRKVRKDIETLEVENEALKMENDEKNQKRLDEIAKELANLKEKQNALNSQFENEKSVFDGISAKKKEID
LLKNEASLAKARGEFQKAAELEYGKIPSLEKEVEILEDKWKKMSENGVLLKNQVDEDLVAGILSKWTGISVQKMLTSEKQ
KFLEVEKHLKESVIGQDKALSALARAIKRNKAGLNADNKPIGSFLFLGPTGVGKTQSAKALAKFLFDDEKAMIRFDMSEF
MEKHSVSRLLGAPPGYIGHEEGGELTEAVRRKPYSVLLFDEVEKAHKDVFNVLLGILDDSRATDSKGVTVDFKNTIIILT
SNIASSAIMNLSGKEQEDAVKNELKNFFKPEFLNRLDDIITFNPLGKDEAYEIVKLLFKDLQMSLENKGIKASLSENAAL
LIAKDGFDPDFGARPLRRAIYDLIEDKLSDMILADELHENDSIIIDAKDDEIIIKKA
>Mature_856_residues
ANIQDFLTDNMLSNLESAASLAIHSKNTEVVPLHLLWALSVDSTSILNQILNKLNISKEALELEIKSRISKLATSSNVNR
ENIRFSNELINSLENAKGLMSANGDSYLSVDTWLISESQKSPIKEILAQFLDLREFQKELESLRAGRKMDSKTSDETLDS
LNKFGIDLTLKASEGKLDPVIGREEEIERLMQILIRKTKNNPILLGEPGVGKTAIVEALAQRIIKKDVPKSLQNKKVIAL
DMSALIAGAKYRGEFEDRLKAVVNEVIKSENIILFIDEIHTIVGAGASEGSMDAANILKPALARGELHTIGATTLKEYRK
YFEKDAALQRRFQPVNVGEPSVNEALAMLRGIKEKLEIHHNVTINDSALVAAAKLSKRYITDRFLPDKAIDLIDEAAAEL
KMQIESEPSSLRKVRKDIETLEVENEALKMENDEKNQKRLDEIAKELANLKEKQNALNSQFENEKSVFDGISAKKKEIDL
LKNEASLAKARGEFQKAAELEYGKIPSLEKEVEILEDKWKKMSENGVLLKNQVDEDLVAGILSKWTGISVQKMLTSEKQK
FLEVEKHLKESVIGQDKALSALARAIKRNKAGLNADNKPIGSFLFLGPTGVGKTQSAKALAKFLFDDEKAMIRFDMSEFM
EKHSVSRLLGAPPGYIGHEEGGELTEAVRRKPYSVLLFDEVEKAHKDVFNVLLGILDDSRATDSKGVTVDFKNTIIILTS
NIASSAIMNLSGKEQEDAVKNELKNFFKPEFLNRLDDIITFNPLGKDEAYEIVKLLFKDLQMSLENKGIKASLSENAALL
IAKDGFDPDFGARPLRRAIYDLIEDKLSDMILADELHENDSIIIDAKDDEIIIKKA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=329, Percent_Identity=33.7386018237082, Blast_Score=191, Evalue=2e-48,
Organism=Escherichia coli, GI1788943, Length=858, Percent_Identity=47.7855477855478, Blast_Score=805, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=265, Percent_Identity=48.3018867924528, Blast_Score=261, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6320464, Length=716, Percent_Identity=47.2067039106145, Blast_Score=649, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=860, Percent_Identity=39.8837209302326, Blast_Score=600, Evalue=1e-172,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95565; Mature: 95434

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIQDFLTDNMLSNLESAASLAIHSKNTEVVPLHLLWALSVDSTSILNQILNKLNISKE
CCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCHH
ALELEIKSRISKLATSSNVNRENIRFSNELINSLENAKGLMSANGDSYLSVDTWLISESQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCEEEEEEEEECCCC
KSPIKEILAQFLDLREFQKELESLRAGRKMDSKTSDETLDSLNKFGIDLTLKASEGKLDP
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCC
VIGREEEIERLMQILIRKTKNNPILLGEPGVGKTAIVEALAQRIIKKDVPKSLQNKKVIA
CCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCCEEEE
LDMSALIAGAKYRGEFEDRLKAVVNEVIKSENIILFIDEIHTIVGAGASEGSMDAANILK
EEHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHH
PALARGELHTIGATTLKEYRKYFEKDAALQRRFQPVNVGEPSVNEALAMLRGIKEKLEIH
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
HNVTINDSALVAAAKLSKRYITDRFLPDKAIDLIDEAAAELKMQIESEPSSLRKVRKDIE
CCEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TLEVENEALKMENDEKNQKRLDEIAKELANLKEKQNALNSQFENEKSVFDGISAKKKEID
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHH
LLKNEASLAKARGEFQKAAELEYGKIPSLEKEVEILEDKWKKMSENGVLLKNQVDEDLVA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHH
GILSKWTGISVQKMLTSEKQKFLEVEKHLKESVIGQDKALSALARAIKRNKAGLNADNKP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCC
IGSFLFLGPTGVGKTQSAKALAKFLFDDEKAMIRFDMSEFMEKHSVSRLLGAPPGYIGHE
CCCEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCC
EGGELTEAVRRKPYSVLLFDEVEKAHKDVFNVLLGILDDSRATDSKGVTVDFKNTIIILT
CCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEE
SNIASSAIMNLSGKEQEDAVKNELKNFFKPEFLNRLDDIITFNPLGKDEAYEIVKLLFKD
CCHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHH
LQMSLENKGIKASLSENAALLIAKDGFDPDFGARPLRRAIYDLIEDKLSDMILADELHEN
HHHHHHCCCCEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
DSIIIDAKDDEIIIKKA
CCEEEECCCCCEEEECC
>Mature Secondary Structure 
ANIQDFLTDNMLSNLESAASLAIHSKNTEVVPLHLLWALSVDSTSILNQILNKLNISKE
CCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCHH
ALELEIKSRISKLATSSNVNRENIRFSNELINSLENAKGLMSANGDSYLSVDTWLISESQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCEEEEEEEEECCCC
KSPIKEILAQFLDLREFQKELESLRAGRKMDSKTSDETLDSLNKFGIDLTLKASEGKLDP
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCC
VIGREEEIERLMQILIRKTKNNPILLGEPGVGKTAIVEALAQRIIKKDVPKSLQNKKVIA
CCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCCEEEE
LDMSALIAGAKYRGEFEDRLKAVVNEVIKSENIILFIDEIHTIVGAGASEGSMDAANILK
EEHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHH
PALARGELHTIGATTLKEYRKYFEKDAALQRRFQPVNVGEPSVNEALAMLRGIKEKLEIH
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
HNVTINDSALVAAAKLSKRYITDRFLPDKAIDLIDEAAAELKMQIESEPSSLRKVRKDIE
CCEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TLEVENEALKMENDEKNQKRLDEIAKELANLKEKQNALNSQFENEKSVFDGISAKKKEID
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHH
LLKNEASLAKARGEFQKAAELEYGKIPSLEKEVEILEDKWKKMSENGVLLKNQVDEDLVA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHH
GILSKWTGISVQKMLTSEKQKFLEVEKHLKESVIGQDKALSALARAIKRNKAGLNADNKP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCC
IGSFLFLGPTGVGKTQSAKALAKFLFDDEKAMIRFDMSEFMEKHSVSRLLGAPPGYIGHE
CCCEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCC
EGGELTEAVRRKPYSVLLFDEVEKAHKDVFNVLLGILDDSRATDSKGVTVDFKNTIIILT
CCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEE
SNIASSAIMNLSGKEQEDAVKNELKNFFKPEFLNRLDDIITFNPLGKDEAYEIVKLLFKD
CCHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHH
LQMSLENKGIKASLSENAALLIAKDGFDPDFGARPLRRAIYDLIEDKLSDMILADELHEN
HHHHHHCCCCEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
DSIIIDAKDDEIIIKKA
CCEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]