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The map label for this gene is yisQ [H]

Identifier: 57238186

GI number: 57238186

Start: 654687

End: 656003

Strand: Direct

Name: yisQ [H]

Synonym: CJE0722

Alternate gene names: 57238186

Gene position: 654687-656003 (Clockwise)

Preceding gene: 57238188

Following gene: 57238185

Centisome position: 36.83

GC content: 32.35

Gene sequence:

>1317_bases
ATGGCAAAAAAACAACTCTCCTTAACAAGACTTAGTTTTCCTATATTTTGGGATTTGCTTTCTAAGTATTTAACTGTGAT
TATCAATACCGCTATGGTGTCGCATTATTCTAATTTTCTTGTTGGTGCTATGGGCGCTGGAAATCAAATTTTAGATCTTT
TTATCACTATTTTTTCATTTTTAAGTGTGGGTTGTAGTGTGCTGATCGCACAAGCAATTGGTGCAAAAGATCATGTTTTA
GCAAGAAAAGTGATTCATCAAAGTTTGTTCTTAAATGCACTTTTAGGCTTTGTATGCGGTGTGCTTATTTTATGGCATGG
GGAGTATTTGCTTTATCTTTTAAAAATTCCACAAGAATTGCTCAAAGATAGCGAAATTTACTTACATATGCTTGCAATTT
GTTTGTTTTTTGATGCCATAGGTATTGTTTTAGCTGCTATTGTAAGGGTTTATAATATGGCTTATTGGGTCATGTTTATA
GGTTTTTTGATGGATATAGTGGTGATTTGCGGAAATTATTATGTTTTGCATTATACAAAGTCAGAACTTTTTGGAATAGG
GCTTAGTAATATTTTTGCTCGCATTGTTGCTATAGTTGCTTTGTTTGCGATACTTTTTTATAAACTTAAAATTCATCTTA
AAATCAAAGAAATGATAAAACTTGAAAAAGAAGTTTTAAAAAAGGTTTTAAATATAGGTGGATTTTCAGCAGGGGAAAAT
CTTTTGTGGATAGTCCAATACACTATAGCTTTTGCTTTTGTAGCAAGTTTAGGTGAGGCGAGTTTGAGTGTGCAAACGAT
TTATTTTCAAATTTCAATGCTTATCATGCTTATAGGACAAGCTACGAGCATAGCTAATGAAATTATAGTAGGTAAATTAA
TCGGTGCTAGATATGAAAATATAGCTTATAAACACGCTTGGCGTGCTTTATATTTTAGTGTAATAGCGAGTGCTTTAGTG
GCACTTTTGAACTATCTTTGTCAAGATTTTACTATGCAAATTTTAGGGCTTAAAGAAGAGTTAAAAAATTTAATGATACC
TTTATTTGCTCTTTCAATCTTTCTTGAAATTTCACGAACTTTTAATATAGTTATGGTAAATTCCTTGCGCGCAAGTGGCG
ATGCTAAGTTTCCATTTTTTAGCGGACTTGTTTTTATGATGGGGGTATCTTTACCTGTGGGTTATGTGCTTTGTTTTCAT
TTTAATCTTGGAATTTTAGGGGTTTGGATAGGATTTTGTGCAGATGAGTTTTTGCGTGGAATGGTAAATTCATACAGATG
GAAAAGCAAAAAATGGCAAGGCAAAGCTCTAGTTTAA

Upstream 100 bases:

>100_bases
TAACAAATTGAGTATATTAAATATTTATATTTAAAAAAGTAATTTTTAAGTAGAATTGTTTTTTAAAAGAAATATTTAAA
AAAAGAGATAAGATAATATC

Downstream 100 bases:

>100_bases
AATCATTTATTTATAAAGATGAGTGCTATTTTTATTCTAAAAAACGCATAAAAACTTTAAGATTAAGGCTCAATGAAAGG
GGTGAATTTGTTCTTAGCAT

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MAKKQLSLTRLSFPIFWDLLSKYLTVIINTAMVSHYSNFLVGAMGAGNQILDLFITIFSFLSVGCSVLIAQAIGAKDHVL
ARKVIHQSLFLNALLGFVCGVLILWHGEYLLYLLKIPQELLKDSEIYLHMLAICLFFDAIGIVLAAIVRVYNMAYWVMFI
GFLMDIVVICGNYYVLHYTKSELFGIGLSNIFARIVAIVALFAILFYKLKIHLKIKEMIKLEKEVLKKVLNIGGFSAGEN
LLWIVQYTIAFAFVASLGEASLSVQTIYFQISMLIMLIGQATSIANEIIVGKLIGARYENIAYKHAWRALYFSVIASALV
ALLNYLCQDFTMQILGLKEELKNLMIPLFALSIFLEISRTFNIVMVNSLRASGDAKFPFFSGLVFMMGVSLPVGYVLCFH
FNLGILGVWIGFCADEFLRGMVNSYRWKSKKWQGKALV

Sequences:

>Translated_438_residues
MAKKQLSLTRLSFPIFWDLLSKYLTVIINTAMVSHYSNFLVGAMGAGNQILDLFITIFSFLSVGCSVLIAQAIGAKDHVL
ARKVIHQSLFLNALLGFVCGVLILWHGEYLLYLLKIPQELLKDSEIYLHMLAICLFFDAIGIVLAAIVRVYNMAYWVMFI
GFLMDIVVICGNYYVLHYTKSELFGIGLSNIFARIVAIVALFAILFYKLKIHLKIKEMIKLEKEVLKKVLNIGGFSAGEN
LLWIVQYTIAFAFVASLGEASLSVQTIYFQISMLIMLIGQATSIANEIIVGKLIGARYENIAYKHAWRALYFSVIASALV
ALLNYLCQDFTMQILGLKEELKNLMIPLFALSIFLEISRTFNIVMVNSLRASGDAKFPFFSGLVFMMGVSLPVGYVLCFH
FNLGILGVWIGFCADEFLRGMVNSYRWKSKKWQGKALV
>Mature_437_residues
AKKQLSLTRLSFPIFWDLLSKYLTVIINTAMVSHYSNFLVGAMGAGNQILDLFITIFSFLSVGCSVLIAQAIGAKDHVLA
RKVIHQSLFLNALLGFVCGVLILWHGEYLLYLLKIPQELLKDSEIYLHMLAICLFFDAIGIVLAAIVRVYNMAYWVMFIG
FLMDIVVICGNYYVLHYTKSELFGIGLSNIFARIVAIVALFAILFYKLKIHLKIKEMIKLEKEVLKKVLNIGGFSAGENL
LWIVQYTIAFAFVASLGEASLSVQTIYFQISMLIMLIGQATSIANEIIVGKLIGARYENIAYKHAWRALYFSVIASALVA
LLNYLCQDFTMQILGLKEELKNLMIPLFALSIFLEISRTFNIVMVNSLRASGDAKFPFFSGLVFMMGVSLPVGYVLCFHF
NLGILGVWIGFCADEFLRGMVNSYRWKSKKWQGKALV

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=439, Percent_Identity=23.0068337129841, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49270; Mature: 49139

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AKKQLSLTRLSFPIFWDLLSKYLTVIINTAMVSHYSNFLVGAMGAGNQILDLFITIFSF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LSVGCSVLIAQAIGAKDHVLARKVIHQSLFLNALLGFVCGVLILWHGEYLLYLLKIPQEL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKDSEIYLHMLAICLFFDAIGIVLAAIVRVYNMAYWVMFIGFLMDIVVICGNYYVLHYTK
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEH
SELFGIGLSNIFARIVAIVALFAILFYKLKIHLKIKEMIKLEKEVLKKVLNIGGFSAGEN
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LLWIVQYTIAFAFVASLGEASLSVQTIYFQISMLIMLIGQATSIANEIIVGKLIGARYEN
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAYKHAWRALYFSVIASALVALLNYLCQDFTMQILGLKEELKNLMIPLFALSIFLEISRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNIVMVNSLRASGDAKFPFFSGLVFMMGVSLPVGYVLCFHFNLGILGVWIGFCADEFLRG
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVNSYRWKSKKWQGKALV
HHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]