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The map label for this gene is hypD [H]

Identifier: 57238180

GI number: 57238180

Start: 661443

End: 662534

Strand: Direct

Name: hypD [H]

Synonym: CJE0728

Alternate gene names: 57238180

Gene position: 661443-662534 (Clockwise)

Preceding gene: 57238181

Following gene: 57238179

Centisome position: 37.21

GC content: 35.26

Gene sequence:

>1092_bases
ATGAATTTCATCGATGAATTTAGAGATAAAGAAAGCATTTTAGCTTTAAAAAAACTTATAGAACAAGAACTTAAAAATCC
TATCAATATCATGGAAATTTGCGGTGGGCATACGCATAGTATTATGAAATATGCCCTGCCTTCTATTTTGCCAAAGGAAA
TTAACTTTATCCATGGGCCAGGATGTCCTGTTTGTGTTATGCCAAGAGTTCGCATTGATACAGCTATTAAGCTAGCCTCC
ATGAAAGATACGATTTTTTGTACCTTAGGGGATCTTTTAAGGGTGCCTGGAAGTGAAATTTCTTTACTGGATTTAAGAGC
TAAAGGGGCTGATGTTAGAGCACTTTATTCTCCGCTTGAAGTTTTGGAAATCGCTAAGCAAAATTTAAACAAAAATATCA
TCTTTTTTGCTATAGGTTTTGAAACCACTACGCCTATGAGTGCTTTACTTCTTCAAAAGGTTATAGAAGAAAAAATAAAT
AATGTCTTTTTTCATATCAATCATATCACGGTTCCAGCACCTGTGGAAGCGATCATGAATGATGAAAATGTAAAAATCAA
TGCTTTTTTAGGCCCTTCTCATGTGAGTGTGATAACAGGTTATGGTATTTATGAGCCTTTAGCAGCAAAGTTTAAAACCC
CTATAGCGGTGAGTGGTTTTGAGCCAGTTGATATTTTAGAAAGTGTGTTAAATATCATAAAACAAAGCAATGAAGGCACT
TTTAAAGTGTATAATCAATACAAAAGAGCCGTAAGCAAAGAAGGCAATGTTAAAGCACAAAATTTAGTAAAAAAATACTT
TAGGGTGTGTGATTTTGAATTTCGTGGCTTAGGACTTATTAAAAATGGAGGCTTGGAGTTAAAAGAAGAATTTAGCGCTT
ACGATGCGAGTAAAAAATTTGATTGTACGGTGCAAAGTAAAAATGAAAGCAAAGCCTGTATTTGTGGGCAAATTTTAAGA
GGTTTGGCCAAGCCTTATGATTGTAAAGTTTTTGGCAAGGCTTGTACGCCAAGAAGTCCTATAGGAAGTTGTATGGTTTC
TGGCGAGGGTGCTTGTGCGGCGTATTATAAATACTCAAAGGTGAATGCATGA

Upstream 100 bases:

>100_bases
GACAAAGAAGCTGCACTAGAAAGCATTAAAACCTATCAAGAAATAGTAGAAAAAATGAATAGTGGAGAGATAAAAAGTGA
TGAGGGAGATTTGGGTTTAA

Downstream 100 bases:

>100_bases
AAAATATTTCCTTAGCCCACGGAGGCGGTGGAGAAGAGATGAATGAGCTTTTAACTAAGCTTTTTAAGATCTTTGATAAT
GAAATTTTAAACGCAAATAA

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNFIDEFRDKESILALKKLIEQELKNPINIMEICGGHTHSIMKYALPSILPKEINFIHGPGCPVCVMPRVRIDTAIKLAS
MKDTIFCTLGDLLRVPGSEISLLDLRAKGADVRALYSPLEVLEIAKQNLNKNIIFFAIGFETTTPMSALLLQKVIEEKIN
NVFFHINHITVPAPVEAIMNDENVKINAFLGPSHVSVITGYGIYEPLAAKFKTPIAVSGFEPVDILESVLNIIKQSNEGT
FKVYNQYKRAVSKEGNVKAQNLVKKYFRVCDFEFRGLGLIKNGGLELKEEFSAYDASKKFDCTVQSKNESKACICGQILR
GLAKPYDCKVFGKACTPRSPIGSCMVSGEGACAAYYKYSKVNA

Sequences:

>Translated_363_residues
MNFIDEFRDKESILALKKLIEQELKNPINIMEICGGHTHSIMKYALPSILPKEINFIHGPGCPVCVMPRVRIDTAIKLAS
MKDTIFCTLGDLLRVPGSEISLLDLRAKGADVRALYSPLEVLEIAKQNLNKNIIFFAIGFETTTPMSALLLQKVIEEKIN
NVFFHINHITVPAPVEAIMNDENVKINAFLGPSHVSVITGYGIYEPLAAKFKTPIAVSGFEPVDILESVLNIIKQSNEGT
FKVYNQYKRAVSKEGNVKAQNLVKKYFRVCDFEFRGLGLIKNGGLELKEEFSAYDASKKFDCTVQSKNESKACICGQILR
GLAKPYDCKVFGKACTPRSPIGSCMVSGEGACAAYYKYSKVNA
>Mature_363_residues
MNFIDEFRDKESILALKKLIEQELKNPINIMEICGGHTHSIMKYALPSILPKEINFIHGPGCPVCVMPRVRIDTAIKLAS
MKDTIFCTLGDLLRVPGSEISLLDLRAKGADVRALYSPLEVLEIAKQNLNKNIIFFAIGFETTTPMSALLLQKVIEEKIN
NVFFHINHITVPAPVEAIMNDENVKINAFLGPSHVSVITGYGIYEPLAAKFKTPIAVSGFEPVDILESVLNIIKQSNEGT
FKVYNQYKRAVSKEGNVKAQNLVKKYFRVCDFEFRGLGLIKNGGLELKEEFSAYDASKKFDCTVQSKNESKACICGQILR
GLAKPYDCKVFGKACTPRSPIGSCMVSGEGACAAYYKYSKVNA

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=368, Percent_Identity=41.304347826087, Blast_Score=338, Evalue=4e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 40204; Mature: 40204

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFIDEFRDKESILALKKLIEQELKNPINIMEICGGHTHSIMKYALPSILPKEINFIHGP
CCCHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHCHHHCCEEECC
GCPVCVMPRVRIDTAIKLASMKDTIFCTLGDLLRVPGSEISLLDLRAKGADVRALYSPLE
CCCEEECCCEEHHHHEEEECCCCCEEEEHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHH
VLEIAKQNLNKNIIFFAIGFETTTPMSALLLQKVIEEKINNVFFHINHITVPAPVEAIMN
HHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHCC
DENVKINAFLGPSHVSVITGYGIYEPLAAKFKTPIAVSGFEPVDILESVLNIIKQSNEGT
CCCEEEEEEECCCCEEEEECCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCH
FKVYNQYKRAVSKEGNVKAQNLVKKYFRVCDFEFRGLGLIKNGGLELKEEFSAYDASKKF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCE
DCTVQSKNESKACICGQILRGLAKPYDCKVFGKACTPRSPIGSCMVSGEGACAAYYKYSK
EEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEECCCCCEEEEEEECC
VNA
CCC
>Mature Secondary Structure
MNFIDEFRDKESILALKKLIEQELKNPINIMEICGGHTHSIMKYALPSILPKEINFIHGP
CCCHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHCHHHCCEEECC
GCPVCVMPRVRIDTAIKLASMKDTIFCTLGDLLRVPGSEISLLDLRAKGADVRALYSPLE
CCCEEECCCEEHHHHEEEECCCCCEEEEHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHH
VLEIAKQNLNKNIIFFAIGFETTTPMSALLLQKVIEEKINNVFFHINHITVPAPVEAIMN
HHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHCC
DENVKINAFLGPSHVSVITGYGIYEPLAAKFKTPIAVSGFEPVDILESVLNIIKQSNEGT
CCCEEEEEEECCCCEEEEECCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCH
FKVYNQYKRAVSKEGNVKAQNLVKKYFRVCDFEFRGLGLIKNGGLELKEEFSAYDASKKF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCE
DCTVQSKNESKACICGQILRGLAKPYDCKVFGKACTPRSPIGSCMVSGEGACAAYYKYSK
EEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEECCCCCEEEEEEECC
VNA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275; 8510650 [H]