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The map label for this gene is mrdB [H]

Identifier: 57238153

GI number: 57238153

Start: 1334487

End: 1335587

Strand: Direct

Name: mrdB [H]

Synonym: CJE1417

Alternate gene names: 57238153

Gene position: 1334487-1335587 (Clockwise)

Preceding gene: 57238135

Following gene: 57238154

Centisome position: 75.06

GC content: 28.25

Gene sequence:

>1101_bases
TTGTTTAGATTAGATAGAAGAATTTTAACTCATTTTGACTATATGCAACCCATTTTATTTTTACCCATAATTCTTATTTC
ATTTTTCTTAATCTTTGAAGCTAATCCTTTTTTAGCAGAAAAACAGTTTGTTTATGCCTGTGTGGGATTGTTTGCTTTTA
TGGTTTTTTTCTTCTTTCCCATAAGGAAATTTATTTGGATTATTCCTGTTGCTTATTGGATTAATATTTTTTTATTGCTA
AGCGTAGATATTTTTGGGGTTGAAAAATTAGGTGCTAAAAGATGGCTTGAAATTCCTTTTACTCACTTTACTATACAACC
TTCTGAAATTTTTAAACCTAGTTTTATTTTAATGCTTGCCTATCTTATTTATCAAAATCCTCCTCCAAAAAATGGATACA
AACTTAAACAATTCATCAAACTTAGCTTTTACATCATCTTGCCTTTTTTGCTAATTGCAAAAGAACCTGATTTAGGAAGT
GCTATGGTTTTACTACTTGTTGGTTTTGGAGTGCTTTTTATCATGGGAGTTCATTATAAAATTTGGTTAAGTATTGTTAT
AGCTATAAGCGTTAGCTCTCCTATTATTTATACACATCTTTTAAAGCCCTACCAAAAGCAAAGAATTCATGATTTTATTT
CAGAAAAACCAAGTTATCAAGTAACCCAATCAATGATAGCTATTGGAAATGGTGGTTTAACTGGAAAATCTCAAGATGAA
GCTACACAAACTCATTTTAAATTTTTACCTATTTCAACTAGCGATTTTATCTTCGCTTACATGATAGAAAGATTTGGATT
TATTGGGGGATTAACATTAATTATATTTTATATTTTACTTATTTTTCATCTACTTAGTTTAAATTATAAACTTAAAGATG
ATTATTTTGCTAGAGTTGCTATTAATTGCGTTGCATTATTTATTTTTATTTACGCGGCAGTAAATATCTCAATGACTATA
GGTTTTGCACCAGTAGTTGGGATCCCTTTGCCTTTTTTTAGTTATGGTGGAAGTTCTTTTACTATTTTTATGATTTTTTT
TGGAATTTTACAGCATTTAATCACTTTTAGATATTTTTGGACGGATATAAAGGCTAAATAA

Upstream 100 bases:

>100_bases
TCATCTACTAAAAAAGTTTGCATTTTTTCCTTAGAGGTTTTGATAAATTTAAAATTTTAGTTTATAATTATAGCTTTATA
TTACCAACTGAAGGCAAATT

Downstream 100 bases:

>100_bases
AATATTTTTAAGCATTAATAAGATATAATTTTATCTTTTAATTCAACTTAGGCGGATTTATAGCTCAGTTGGTTAGAGCA
ACCGGCTCATAACCGGTTGG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MFRLDRRILTHFDYMQPILFLPIILISFFLIFEANPFLAEKQFVYACVGLFAFMVFFFFPIRKFIWIIPVAYWINIFLLL
SVDIFGVEKLGAKRWLEIPFTHFTIQPSEIFKPSFILMLAYLIYQNPPPKNGYKLKQFIKLSFYIILPFLLIAKEPDLGS
AMVLLLVGFGVLFIMGVHYKIWLSIVIAISVSSPIIYTHLLKPYQKQRIHDFISEKPSYQVTQSMIAIGNGGLTGKSQDE
ATQTHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKDDYFARVAINCVALFIFIYAAVNISMTI
GFAPVVGIPLPFFSYGGSSFTIFMIFFGILQHLITFRYFWTDIKAK

Sequences:

>Translated_366_residues
MFRLDRRILTHFDYMQPILFLPIILISFFLIFEANPFLAEKQFVYACVGLFAFMVFFFFPIRKFIWIIPVAYWINIFLLL
SVDIFGVEKLGAKRWLEIPFTHFTIQPSEIFKPSFILMLAYLIYQNPPPKNGYKLKQFIKLSFYIILPFLLIAKEPDLGS
AMVLLLVGFGVLFIMGVHYKIWLSIVIAISVSSPIIYTHLLKPYQKQRIHDFISEKPSYQVTQSMIAIGNGGLTGKSQDE
ATQTHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKDDYFARVAINCVALFIFIYAAVNISMTI
GFAPVVGIPLPFFSYGGSSFTIFMIFFGILQHLITFRYFWTDIKAK
>Mature_366_residues
MFRLDRRILTHFDYMQPILFLPIILISFFLIFEANPFLAEKQFVYACVGLFAFMVFFFFPIRKFIWIIPVAYWINIFLLL
SVDIFGVEKLGAKRWLEIPFTHFTIQPSEIFKPSFILMLAYLIYQNPPPKNGYKLKQFIKLSFYIILPFLLIAKEPDLGS
AMVLLLVGFGVLFIMGVHYKIWLSIVIAISVSSPIIYTHLLKPYQKQRIHDFISEKPSYQVTQSMIAIGNGGLTGKSQDE
ATQTHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKDDYFARVAINCVALFIFIYAAVNISMTI
GFAPVVGIPLPFFSYGGSSFTIFMIFFGILQHLITFRYFWTDIKAK

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=325, Percent_Identity=36.9230769230769, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1786277, Length=276, Percent_Identity=31.1594202898551, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42436; Mature: 42436

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRLDRRILTHFDYMQPILFLPIILISFFLIFEANPFLAEKQFVYACVGLFAFMVFFFFP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IRKFIWIIPVAYWINIFLLLSVDIFGVEKLGAKRWLEIPFTHFTIQPSEIFKPSFILMLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCEEEEECHHHHHCHHHHHHHH
YLIYQNPPPKNGYKLKQFIKLSFYIILPFLLIAKEPDLGSAMVLLLVGFGVLFIMGVHYK
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IWLSIVIAISVSSPIIYTHLLKPYQKQRIHDFISEKPSYQVTQSMIAIGNGGLTGKSQDE
HHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCH
ATQTHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKDDYFARVA
HHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHH
INCVALFIFIYAAVNISMTIGFAPVVGIPLPFFSYGGSSFTIFMIFFGILQHLITFRYFW
HHHHHHHHHHHHHHHHHEEECCHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
TDIKAK
HHHCCC
>Mature Secondary Structure
MFRLDRRILTHFDYMQPILFLPIILISFFLIFEANPFLAEKQFVYACVGLFAFMVFFFFP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IRKFIWIIPVAYWINIFLLLSVDIFGVEKLGAKRWLEIPFTHFTIQPSEIFKPSFILMLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCEEEEECHHHHHCHHHHHHHH
YLIYQNPPPKNGYKLKQFIKLSFYIILPFLLIAKEPDLGSAMVLLLVGFGVLFIMGVHYK
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IWLSIVIAISVSSPIIYTHLLKPYQKQRIHDFISEKPSYQVTQSMIAIGNGGLTGKSQDE
HHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCH
ATQTHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKDDYFARVA
HHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHH
INCVALFIFIYAAVNISMTIGFAPVVGIPLPFFSYGGSSFTIFMIFFGILQHLITFRYFW
HHHHHHHHHHHHHHHHHEEECCHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
TDIKAK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]